Selected Article


Determination of Antimicrobial and Biological Activities of Salvia sclarea L. (Lamiaceae) Extracts


In the present study, Salvia sclarea L. was collected duringto flowering stage in 2016, Sarıcakaya (Eskişehir/Turkey) and dried medicinalplant materials were macerated with 70% MeOH. The antimicrobial activity of Salvia sclarea extracts was determinedwith minimum inhibitory concentration (MIC) assay against Escherichia coli ATCC 35218, Staphylococcusaureus ATCC 29213 and Candidaalbicans ATCC 90028. The antibiofilm activity of Salvia sclarea extracts was determined against Staphylococcusaureus ATCC 29213 and Staphylococcus epidermidis ATCC 14990. And the preliminary cytotoxicity assessment of extracts was tested withBrine Shrimp Lethality Assay against model organism Artemia salina nauplii. As aresult, Salvia sclarea extract showedremarkably antibacterial activity while it showed no effect on Candida albicans ATCC 90028. Moreover,antibiofilm activity could not be determined. The lethalityeffect also could not be determined due to high dose concentrations.