ARTICLES
7 Article(s)
Document(s)
Title
Graff, Mariaelisa;Scott, Robert A.;Justice, Anne E.;Young, Kristin L.;Feitosa, Mary F.;Barata, Llilda;Winkler, Thomas W.;Chu, Audrey Y.;Mahajan, Anubha;Hadley, David;Xue, Luting;Workalemahu, Tsegaselassie;Heard-Costa, Nancy L.;den Hoed, Marcel;Ahluwalia, Tarunveer S.;Qi, Qibin;Ngwa, Julius S.;Renström, Frida;Quaye, Lydia;Eicher, John D.;Hayes, James E.;Cornelis, Marilyn;Kutalik, Zoltan;Lim, Elise;Luan, Jian’an;Huffman, Jennifer E.;Zhang, Weihua;Zhao, Wei;Griffin, Paula J.;Haller, Toomas;Ahmad, Shafqat;Marques-Vidal, Pedro M.;Bien, Stephanie;Yengo, Loic;Teumer, Alexander;Smith, Albert Vernon;Kumari, Meena;Harder, Marie Neergaard;Justesen, Johanne Marie;Kleber, Marcus E.;Hollensted, Mette;Lohman, Kurt;Rivera, Natalia V.;Whitfield, John B.;Zhao, Jing Hua;Stringham, Heather M.;Lyytikäinen, Leo-Pekka;Huppertz, Charlotte;Willemsen, Gonneke;Peyrot, Wouter J.;Wu, Ying;Kristiansson, Kati;Demirkan, Ayse;Fornage, Myriam;Hassinen, Maija;Bielak, Lawrence F.;Cadby, Gemma;Tanaka, Toshiko;Mägi, Reedik;van der Most, Peter J.;Jackson, Anne U.;Bragg-Gresham, Jennifer L.;Vitart, Veronique;Marten, Jonathan;Navarro, Pau;Bellis, Claire;Pasko, Dorota;Johansson, Åsa;Snitker, Søren;Cheng, Yu-Ching;Eriksson, Joel;Lim, Unhee;Aadahl, Mette;Adair, Linda S.;Amin, Najaf;Balkau, Beverley;Auvinen, Juha;Beilby, John;Bergman, Richard N.;Bergmann, Sven;Bertoni, Alain G.;Blangero, John;Bonnefond, Amélie;Bonnycastle, Lori L.;Borja, Judith B.;Brage, Søren;Busonero, Fabio;Buyske, Steve;Campbell, Harry;Chines, Peter S.;Collins, Francis S.;Corre, Tanguy;Smith, George Davey;Delgado, Graciela E.;Dueker, Nicole;Dörr, Marcus;Ebeling, Tapani;Eiriksdottir, Gudny;Esko, Tõnu;Faul, Jessica D.;Fu, Mao;Færch, Kristine;Gieger, Christian;Gläser, Sven;Gong, Jian;Gordon-Larsen, Penny;Grallert, Harald;Grammer, Tanja B.;Grarup, Niels;van Grootheest, Gerard;Harald, Kennet;Hastie, Nicholas D.;Havulinna, Aki S.;Hernandez, Dena;Hindorff, Lucia;Hocking, Lynne J.;Holmens, Oddgeir L.;Holzapfel, Christina;Hottenga, Jouke Jan;Huang, Jie;Huang, Tao;Hui, Jennie;Huth, Cornelia;Hutri-Kähönen, Nina;James, Alan L.;Jansson, John-Olov;Jhun, Min A.;Juonala, Markus;Kinnunen, Leena;Koistinen, Heikki A.;Kolcic, Ivana;Komulainen, Pirjo;Kuusisto, Johanna;Kvaløy, Kirsti;Kähönen, Mika;Lakka, Timo A.;Launer, Lenore J.;Lehne, Benjamin;Lindgren, Cecilia M.;Lorentzon, Mattias;Luben, Robert;Marre, Michel;Milaneschi, Yuri;Monda, Keri L.;Montgomery, Grant W.;De Moor, Marleen H. M.;Mulas, Antonella;Müller-Nurasyid, Martina;Musk, A. W.;Männikkö, Reija;Männistö, Satu;Narisu, Narisu;Nauck, Matthias;Nettleton, Jennifer A.;Nolte, Ilja M.;Oldehinkel, Albertine J.;Olden, Matthias;Ong, Ken K.;Padmanabhan, Sandosh;Paternoster, Lavinia;Perez, Jeremiah;Perola, Markus;Peters, Annette;Peters, Ulrike;Peyser, Patricia A.;Prokopenko, Inga;Puolijoki, Hannu;Raitakari, Olli T.;Rankinen, Tuomo;Rasmussen-Torvik, Laura J.;Rawal, Rajesh;Ridker, Paul M.;Rose, Lynda M.;Rudan, Igor;Sarti, Cinzia;Sarzynski, Mark A.;Savonen, Kai;Scott, William R.;Sanna, Serena;Shuldiner, Alan R.;Sidney, Steve;Silbernagel, Günther;Smith, Blair H.;Smith, Jennifer A.;Snieder, Harold;Stančáková, Alena;Sternfeld, Barbara;Swift, Amy J.;Tammelin, Tuija;Tan, Sian-Tsung;Thorand, Barbara;Thuillier, Dorothée;Vandenput, Liesbeth;Vestergaard, Henrik;van Vliet-Ostaptchouk, Jana V.;Vohl, Marie-Claude;Völker, Uwe;Waeber, Gérard;Walker, Mark;Wild, Sarah;Wong, Andrew;Wright, Alan F.;Zillikens, M. Carola;Zubair, Niha;Haiman, Christopher A.;Lemarchand, Loic;Gyllensten, Ulf;Ohlsson, Claes;Hofman, Albert;Rivadeneira, Fernando;Uitterlinden, André G.;Pérusse, Louis;Wilson, James F.;Hayward, Caroline;Polasek, Ozren;Cucca, Francesco;Hveem, Kristian;Hartman, Catharina A.;Tönjes, Anke;Bandinelli, Stefania;Palmer, Lyle J.;Kardia, Sharon L. R.;Rauramaa, Rainer;Sørensen, Thorkild I. A.;Tuomilehto, Jaakko;Salomaa, Veikko;Penninx, Brenda W. J. H.;de Geus, Eco J. C.;Boomsma, Dorret I.;Lehtimäki, Terho;Mangino, Massimo;Laakso, Markku;Bouchard, Claude;Martin, Nicholas G.;Kuh, Diana;Liu, Yongmei;Linneberg, Allan;März, Winfried;Strauch, Konstantin;Kivimäki, Mika;Harris, Tamara B.;Gudnason, Vilmundur;Völzke, Henry;Qi, Lu;Järvelin, Marjo-Riitta;Chambers, John C.;Kooner, Jaspal S.;Froguel, Philippe;Kooperberg, Charles;Vollenweider, Peter;Hallmans, Göran;Hansen, Torben;Pedersen, Oluf;Metspalu, Andres;Wareham, Nicholas J.;Langenberg, Claudia;Weir, David R.;Porteous, David J.;Boerwinkle, Eric;Chasman, Daniel I.;Abecasis, Gonçalo R.;Barroso, Inês;McCarthy, Mark I.;Frayling, Timothy M.;O’Connell, Jeffrey R.;van Duijn, Cornelia M.;Boehnke, Michael;Heid, Iris M.;Mohlke, Karen L.;Strachan, David P.;Fox, Caroline S.;Liu, Ching-Ti;Hirschhorn, Joel N.;Klein, Robert J.;Johnson, Andrew D.;Borecki, Ingrid B.;Franks, Paul W.;North, Kari E.;Cupples, L. Adrienne;Loos, Ruth J. F.;Kilpeläinen, Tuomas O.
Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumfer...
An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associa...
Graff, Mariaelisa;Scott, Robert A.;Justice, Anne E.;Young, Kristin L.;Feitosa, Mary F.;Barata, Llilda;Winkler, Thomas W.;Chu, Audrey Y.;Mahajan, Anubha;Hadley, David;Xue, Luting;Workalemahu, Tsegaselassie;Heard-Costa, Nancy L.;den Hoed, Marcel;Ahluwalia, Tarunveer S.;Qi, Qibin;Ngwa, Julius S.;Renström, Frida;Quaye, Lydia;Eicher, John D.;Hayes, James E.;Cornelis, Marilyn;Kutalik, Zoltan;Lim, Elise;Luan, Jian’an;Huffman, Jennifer E.;Zhang, Weihua;Zhao, Wei;Griffin, Paula J.;Haller, Toomas;Ahmad, Shafqat;Marques-Vidal, Pedro M.;Bien, Stephanie;Yengo, Loic;Teumer, Alexander;Smith, Albert Vernon;Kumari, Meena;Harder, Marie Neergaard;Justesen, Johanne Marie;Kleber, Marcus E.;Hollensted, Mette;Lohman, Kurt;Rivera, Natalia V.;Whitfield, John B.;Zhao, Jing Hua;Stringham, Heather M.;Lyytikäinen, Leo-Pekka;Huppertz, Charlotte;Willemsen, Gonneke;Peyrot, Wouter J.;Wu, Ying;Kristiansson, Kati;Demirkan, Ayse;Fornage, Myriam;Hassinen, Maija;Bielak, Lawrence F.;Cadby, Gemma;Tanaka, Toshiko;Mägi, Reedik;van der Most, Peter J.;Jackson, Anne U.;Bragg-Gresham, Jennifer L.;Vitart, Veronique;Marten, Jonathan;Navarro, Pau;Bellis, Claire;Pasko, Dorota;Johansson, Åsa;Snitker, Søren;Cheng, Yu-Ching;Eriksson, Joel;Lim, Unhee;Aadahl, Mette;Adair, Linda S.;Amin, Najaf;Balkau, Beverley;Auvinen, Juha;Beilby, John;Bergman, Richard N.;Bergmann, Sven;Bertoni, Alain G.;Blangero, John;Bonnefond, Amélie;Bonnycastle, Lori L.;Borja, Judith B.;Brage, Søren;Busonero, Fabio;Buyske, Steve;Campbell, Harry;Chines, Peter S.;Collins, Francis S.;Corre, Tanguy;Smith, George Davey;Delgado, Graciela E.;Dueker, Nicole;Dörr, Marcus;Ebeling, Tapani;Eiriksdottir, Gudny;Esko, Tõnu;Faul, Jessica D.;Fu, Mao;Færch, Kristine;Gieger, Christian;Gläser, Sven;Gong, Jian;Gordon-Larsen, Penny;Grallert, Harald;Grammer, Tanja B.;Grarup, Niels;van Grootheest, Gerard;Harald, Kennet;Hastie, Nicholas D.;Havulinna, Aki S.;Hernandez, Dena;Hindorff, Lucia;Hocking, Lynne J.;Holmens, Oddgeir L.;Holzapfel, Christina;Hottenga, Jouke Jan;Huang, Jie;Huang, Tao;Hui, Jennie;Huth, Cornelia;Hutri-Kähönen, Nina;James, Alan L.;Jansson, John-Olov;Jhun, Min A.;Juonala, Markus;Kinnunen, Leena;Koistinen, Heikki A.;Kolcic, Ivana;Komulainen, Pirjo;Kuusisto, Johanna;Kvaløy, Kirsti;Kähönen, Mika;Lakka, Timo A.;Launer, Lenore J.;Lehne, Benjamin;Lindgren, Cecilia M.;Lorentzon, Mattias;Luben, Robert;Marre, Michel;Milaneschi, Yuri;Monda, Keri L.;Montgomery, Grant W.;De Moor, Marleen H. M.;Mulas, Antonella;Müller-Nurasyid, Martina;Musk, A. W.;Männikkö, Reija;Männistö, Satu;Narisu, Narisu;Nauck, Matthias;Nettleton, Jennifer A.;Nolte, Ilja M.;Oldehinkel, Albertine J.;Olden, Matthias;Ong, Ken K.;Padmanabhan, Sandosh;Paternoster, Lavinia;Perez, Jeremiah;Perola, Markus;Peters, Annette;Peters, Ulrike;Peyser, Patricia A.;Prokopenko, Inga;Puolijoki, Hannu;Raitakari, Olli T.;Rankinen, Tuomo;Rasmussen-Torvik, Laura J.;Rawal, Rajesh;Ridker, Paul M.;Rose, Lynda M.;Rudan, Igor;Sarti, Cinzia;Sarzynski, Mark A.;Savonen, Kai;Scott, William R.;Sanna, Serena;Shuldiner, Alan R.;Sidney, Steve;Silbernagel, Günther;Smith, Blair H.;Smith, Jennifer A.;Snieder, Harold;Stančáková, Alena;Sternfeld, Barbara;Swift, Amy J.;Tammelin, Tuija;Tan, Sian-Tsung;Thorand, Barbara;Thuillier, Dorothée;Vandenput, Liesbeth;Vestergaard, Henrik;van Vliet-Ostaptchouk, Jana V.;Vohl, Marie-Claude;Völker, Uwe;Waeber, Gérard;Walker, Mark;Wild, Sarah;Wong, Andrew;Wright, Alan F.;Zillikens, M. Carola;Zubair, Niha;Haiman, Christopher A.;Lemarchand, Loic;Gyllensten, Ulf;Ohlsson, Claes;Hofman, Albert;Rivadeneira, Fernando;Uitterlinden, André G.;Pérusse, Louis;Wilson, James F.;Hayward, Caroline;Polasek, Ozren;Cucca, Francesco;Hveem, Kristian;Hartman, Catharina A.;Tönjes, Anke;Bandinelli, Stefania;Palmer, Lyle J.;Kardia, Sharon L. R.;Rauramaa, Rainer;Sørensen, Thorkild I. A.;Tuomilehto, Jaakko;Salomaa, Veikko;Penninx, Brenda W. J. H.;de Geus, Eco J. C.;Boomsma, Dorret I.;Lehtimäki, Terho;Mangino, Massimo;Laakso, Markku;Bouchard, Claude;Martin, Nicholas G.;Kuh, Diana;Liu, Yongmei;Linneberg, Allan;März, Winfried;Strauch, Konstantin;Kivimäki, Mika;Harris, Tamara B.;Gudnason, Vilmundur;Völzke, Henry;Qi, Lu;Järvelin, Marjo-Riitta;Chambers, John C.;Kooner, Jaspal S.;Froguel, Philippe;Kooperberg, Charles;Vollenweider, Peter;Hallmans, Göran;Hansen, Torben;Pedersen, Oluf;Metspalu, Andres;Wareham, Nicholas J.;Langenberg, Claudia;Weir, David R.;Porteous, David J.;Boerwinkle, Eric;Chasman, Daniel I.;Abecasis, Gonçalo R.;Barroso, Inês;McCarthy, Mark I.;Frayling, Timothy M.;O’Connell, Jeffrey R.;van Duijn, Cornelia M.;Boehnke, Michael;Heid, Iris M.;Mohlke, Karen L.;Strachan, David P.;Fox, Caroline S.;Liu, Ching-Ti;Hirschhorn, Joel N.;Klein, Robert J.;Johnson, Andrew D.;Borecki, Ingrid B.;Franks, Paul W.;North, Kari E.;Cupples, L. Adrienne;Loos, Ruth J. F.;Kilpeläinen, Tuomas O.
Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumfer...
Nejentsev, Sergey;Howson, Joanna M. M.;Walker, Neil M.;Szeszko, Jeffrey;Field, Sarah F.;Stevens, Helen E.;Reynolds, Pamela;Hardy, Matthew;King, Erna;Masters, Jennifer;Hulme, John;Maier, Lisa M.;Smyth, Deborah;Bailey, Rebecca;Cooper, Jason D.;Ribas, Gloria;Campbell, R. Duncan;Clayton, David G.;Todd, John A.;Burton, Paul R.;Clayton, David G.;Cardon, Lon R.;Craddock, Nick;Deloukas, Panos;Duncanson, Audrey;Kwiatkowski, Dominic P.;McCarthy, Mark I.;Ouwehand, Willem H.;Samani, Nilesh J.;Todd, John A.;Donnelly, Peter;Barrett, Jeffrey C.;Burton, Paul R.;Davison, Dan;Donnelly, Peter;Easton, Doug;Evans, David;Leung, Hin-Tak;Marchini, Jonathan L.;Morris, Andrew P.;Spencer, Chris C. A.;Tobin, Martin D.;Cardon, Lon R.;Clayton, David G.;Attwood, Antony P.;Boorman, James P.;Cant, Barbara;Everson, Ursula;Hussey, Judith M.;Jolley, Jennifer D.;Knight, Alexandra S.;Koch, Kerstin;Meech, Elizabeth;Nutland, Sarah;Prowse, Christopher V.;Stevens, Helen E.;Taylor, Niall C.;Walters, Graham R.;Walker, Neil M.;Watkins, Nicholas A.;Winzer, Thilo;Todd, John A.;Ouwehand, Willem H.;Jones, Richard W.;McArdle, Wendy L.;Ring, Susan M.;Strachan, David P.;Pembrey, Marcus;Breen, Gerome;St Clair, David;Caesar, Sian;Gordon-Smith, Katherine;Jones, Lisa;Fraser, Christine;Green, Elaine K.;Grozeva, Detelina;Hamshere, Marian L.;Holmans, Peter A.;Jones, Ian R.;Kirov, George;Moskvina, Valentina;Nikolov, Ivan;O’Donovan, Michael C.;Owen, Michael J.;Craddock, Nick;Collier, David A.;Elkin, Amanda;Farmer, Anne;Williamson, Richard;McGuffin, Peter;Young, Allan H.;Nicol Ferrier, I.;Ball, Stephen G.;Balmforth, Anthony J.;Barrett, Jennifer H.;Bishop, D. Timothy;Iles, Mark M.;Maqbool, Azhar;Yuldasheva, Nadira;Hall, Alistair S.;Braund, Peter S.;Burton, Paul R.;Dixon, Richard J.;Mangino, Massimo;Stevens, Suzanne;Tobin, Martin D.;Thompson, John R.;Samani, Nilesh J.;Bredin, Francesca;Tremelling, Mark;Parkes, Miles;Drummond, Hazel;Lees, Charles W.;Nimmo, Elaine R.;Satsangi, Jack;Fisher, Sheila A.;Forbes, Alastair;Lewis, Cathryn M.;Onnie, Clive M.;Prescott, Natalie J.;Sanderson, Jeremy;Mathew, Christopher G.;Barbour, Jamie;Khalid Mohiuddin, M.;Todhunter, Catherine E.;Mansfield, John C.;Ahmad, Tariq;Cummings, Fraser R.;Jewell, Derek P.;Webster, John;Brown, Morris J.;Clayton, David G.;Lathrop, G. Mark;Connell, John;Dominiczak, Anna;Samani, Nilesh J.;Braga, Carolina A.;Burke, Beverley;Dobson, Richard;Gungadoo, Johannie;Lee, Kate L.;Munroe, Patricia B.;Newhouse, Stephen J.;Onipinla, Abiodun;Wallace, Chris;Xue, Mingzhan;Caulfield, Mark;Farrall, Martin;Barton, Anne;Bruce, Ian N.;Donovan, Hannah;Eyre, Steve;Gilbert, Paul D.;Hider, Samantha L.;Hinks, Anne M.;John, Sally L.;Potter, Catherine;Silman, Alan J.;Symmons, Deborah P. M.;Thomson, Wendy;Worthington, Jane;Clayton, David G.;Dunger, David B.;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Widmer, Barry;Todd, John A.;Frayling, Timothy M.;Freathy, Rachel M.;Lango, Hana;Perry, John R. B.;Shields, Beverley M.;Weedon, Michael N.;Hattersley, Andrew T.;Hitman, Graham A.;Walker, Mark;Elliott, Kate S.;Groves, Christopher J.;Lindgren, Cecilia M.;Rayner, Nigel W.;Timpson, Nicholas J.;Zeggini, Eleftheria;McCarthy, Mark I.;Newport, Melanie;Sirugo, Giorgio;Lyons, Emily;Vannberg, Fredrik;Hill, Adrian V. S.;Bradbury, Linda A.;Farrar, Claire;Pointon, Jennifer J.;Wordsworth, Paul;Brown, Matthew A.;Franklyn, Jayne A.;Heward, Joanne M.;Simmonds, Matthew J.;Gough, Stephen C. L.;Seal, Sheila;Stratton, Michael R.;Rahman, Nazneen;Ban, Maria;Goris, An;Sawcer, Stephen J.;Compston, Alastair;Conway, David;Jallow, Muminatou;Newport, Melanie;Sirugo, Giorgio;Rockett, Kirk A.;Kwiatkowski, Dominic P.;Bryan, Claire;Bumpstead, Suzannah J.;Chaney, Amy;Downes, Kate;Ghori, Jilur;Gwilliam, Rhian;Hunt, Sarah E.;Inouye, Michael;Keniry, Andrew;King, Emma;McGinnis, Ralph;Potter, Simon;Ravindrarajah, Rathi;Whittaker, Pamela;Withers, David;Deloukas, Panos;Leung, Hin-Tak;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Todd, John A.;Easton, Doug;Clayton, David G.;Burton, Paul R.;Tobin, Martin D.;Barrett, Jeffrey C.;Evans, David;Morris, Andrew P.;Cardon, Lon R.;Cardin, Niall J.;Davison, Dan;Ferreira, Teresa;Pereira-Gale, Joanne;Hallgrimsdóttir, Ingeleif B.;Howie, Bryan N.;Marchini, Jonathan L.;Spencer, Chris C. A.;Su, Zhan;Ying Teo, Yik;Vukcevic, Damjan;Donnelly, Peter;Bentley, David;Brown, Matthew A.;Cardon, Lon R.;Caulfield, Mark;Clayton, David G.;Compston, Alistair;Craddock, Nick;Deloukas, Panos;Donnelly, Peter;Farrall, Martin;Gough, Stephen C. L.;Hall, Alistair S.;Hattersley, Andrew T.;Hill, Adrian V. S.;Kwiatkowski, Dominic P.;Mathew, Christopher G.;McCarthy, Mark I.;Ouwehand, Willem H.;Parkes, Miles;Pembrey, Marcus;Rahman, Nazneen;Samani, Nilesh J.;Stratton, Michael R.;Todd, John A.;Worthington, Jane
The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. In type 1 diabetes the major gene...
Ikram, M. Arfan;Fornage, Myriam;Smith, Albert V.;Seshadri, Sudha;Schmidt, Reinhold;Debette, Stéphanie;Vrooman, Henri A.;Sigurdsson, Sigurdur;Ropele, Stefan;Taal, H. Rob;Mook-Kanamori, Dennis O.;Coker, Laura H.;Longstreth, W. T.;Niessen, Wiro J.;DeStefano, Anita L.;Beiser, Alexa;Zijdenbos, Alex P.;Struchalin, Maksim;Jack, Clifford R.;Rivadeneira, Fernando;Uitterlinden, Andre G.;Knopman, David S.;Hartikainen, Anna-Liisa;Pennell, Craig E.;Thiering, Elisabeth;Steegers, Eric A. P.;Hakonarson, Hakon;Heinrich, Joachim;Palmer, Lyle J.;Jarvelin, Marjo-Riitta;McCarthy, Mark I.;Grant, Struan F. A.;Pourcain, Beate St;Timpson, Nicholas J.;Smith, George Davey;Sovio, Ulla;Nalls, Mike A.;Au, Rhoda;Hofman, Albert;Gudnason, Haukur;van der Lugt, Aad;Harris, Tamara B.;Meeks, William M.;Vernooij, Meike W.;van Buchem, Mark A.;Catellier, Diane;Jaddoe, Vincent W. V.;Gudnason, Vilmundur;Windham, B. Gwen;Wolf, Philip A.;van Duijn, Cornelia M.;Mosley, Thomas H.;Schmidt, Helena;Launer, Lenore J.;Breteler, Monique M. B.;DeCarli, Charles;Adair, Linda S.;Ang, Wei;Atalay, Mustafa;van Beijsterveldt, Toos;Bergen, Nienke;Benke, Kelly;Berry, Diane;Coin, Lachlan;Davis, Oliver S. P.;Elliott, Paul;Flexeder, Claudia;Frayling, Tim;Gaillard, Romy;Groen-Blokhuis, Maria;Goh, Liang-Kee;Haworth, Claire M. A.;Hadley, Dexter;Hedebrand, Johannes;Hinney, Anke;Hirschhorn, Joel N.;Holloway, John W.;Holst, Claus;Jan Hottenga, Jouke;Horikoshi, Momoko;Huikari, Ville;Hypponen, Elina;Kilpeläinen, Tuomas O.;Kirin, Mirna;Kowgier, Matthew;Lakka, Hanna-Maaria;Lange, Leslie A.;Lawlor, Debbie A.;Lehtimäki, Terho;Lewin, Alex;Lindgren, Cecilia;Lindi, Virpi;Maggi, Reedik;Marsh, Julie;Middeldorp, Christel;Millwood, Iona;Murray, Jeffrey C.;Nivard, Michel;Nohr, Ellen Aagaard;Ntalla, Ioanna;Oken, Emily;Panoutsopoulou, Kalliope;Pararajasingham, Jennifer;Rodriguez, Alina;Salem, Rany M.;Sebert, Sylvain;Siitonen, Niina;Strachan, David P.;Teo, Yik-Ying;Valcárcel, Beatriz;Willemsen, Gonneke;Zeggini, Eleftheria;Boomsma, Dorret I.;Cooper, Cyrus;Gillman, Matthew;Hocher, Berthold;Lakka, Timo A.;Mohlke, Karen L.;Dedoussis, George V.;Ong, Ken K.;Pearson, Ewan R.;Price, Thomas S.;Power, Chris;Raitakari, Olli T.;Saw, Seang-Mei;Scherag, Andre;Simell, Olli;Sørensen, Thorkild I. A.;Wilson, James F.
During aging, intracranial volume remains unchanged and represents maximally attained brain size, while various interacting biological phenomena lead to brain volume loss. Consequently, intracranial volume and brain volume in late life reflect differ...
Nejentsev, Sergey;Howson, Joanna M. M.;Walker, Neil M.;Szeszko, Jeffrey;Field, Sarah F.;Stevens, Helen E.;Reynolds, Pamela;Hardy, Matthew;King, Erna;Masters, Jennifer;Hulme, John;Maier, Lisa M.;Smyth, Deborah;Bailey, Rebecca;Cooper, Jason D.;Ribas, Gloria;Campbell, R. Duncan;Clayton, David G.;Todd, John A.;Burton, Paul R.;Clayton, David G.;Cardon, Lon R.;Craddock, Nick;Deloukas, Panos;Duncanson, Audrey;Kwiatkowski, Dominic P.;McCarthy, Mark I.;Ouwehand, Willem H.;Samani, Nilesh J.;Todd, John A.;Donnelly, Peter;Barrett, Jeffrey C.;Burton, Paul R.;Davison, Dan;Donnelly, Peter;Easton, Doug;Evans, David;Leung, Hin-Tak;Marchini, Jonathan L.;Morris, Andrew P.;Spencer, Chris C. A.;Tobin, Martin D.;Cardon, Lon R.;Clayton, David G.;Attwood, Antony P.;Boorman, James P.;Cant, Barbara;Everson, Ursula;Hussey, Judith M.;Jolley, Jennifer D.;Knight, Alexandra S.;Koch, Kerstin;Meech, Elizabeth;Nutland, Sarah;Prowse, Christopher V.;Stevens, Helen E.;Taylor, Niall C.;Walters, Graham R.;Walker, Neil M.;Watkins, Nicholas A.;Winzer, Thilo;Todd, John A.;Ouwehand, Willem H.;Jones, Richard W.;McArdle, Wendy L.;Ring, Susan M.;Strachan, David P.;Pembrey, Marcus;Breen, Gerome;St Clair, David;Caesar, Sian;Gordon-Smith, Katherine;Jones, Lisa;Fraser, Christine;Green, Elaine K.;Grozeva, Detelina;Hamshere, Marian L.;Holmans, Peter A.;Jones, Ian R.;Kirov, George;Moskvina, Valentina;Nikolov, Ivan;O’Donovan, Michael C.;Owen, Michael J.;Craddock, Nick;Collier, David A.;Elkin, Amanda;Farmer, Anne;Williamson, Richard;McGuffin, Peter;Young, Allan H.;Nicol Ferrier, I.;Ball, Stephen G.;Balmforth, Anthony J.;Barrett, Jennifer H.;Bishop, D. Timothy;Iles, Mark M.;Maqbool, Azhar;Yuldasheva, Nadira;Hall, Alistair S.;Braund, Peter S.;Burton, Paul R.;Dixon, Richard J.;Mangino, Massimo;Stevens, Suzanne;Tobin, Martin D.;Thompson, John R.;Samani, Nilesh J.;Bredin, Francesca;Tremelling, Mark;Parkes, Miles;Drummond, Hazel;Lees, Charles W.;Nimmo, Elaine R.;Satsangi, Jack;Fisher, Sheila A.;Forbes, Alastair;Lewis, Cathryn M.;Onnie, Clive M.;Prescott, Natalie J.;Sanderson, Jeremy;Mathew, Christopher G.;Barbour, Jamie;Khalid Mohiuddin, M.;Todhunter, Catherine E.;Mansfield, John C.;Ahmad, Tariq;Cummings, Fraser R.;Jewell, Derek P.;Webster, John;Brown, Morris J.;Clayton, David G.;Lathrop, G. Mark;Connell, John;Dominiczak, Anna;Samani, Nilesh J.;Braga, Carolina A.;Burke, Beverley;Dobson, Richard;Gungadoo, Johannie;Lee, Kate L.;Munroe, Patricia B.;Newhouse, Stephen J.;Onipinla, Abiodun;Wallace, Chris;Xue, Mingzhan;Caulfield, Mark;Farrall, Martin;Barton, Anne;Bruce, Ian N.;Donovan, Hannah;Eyre, Steve;Gilbert, Paul D.;Hider, Samantha L.;Hinks, Anne M.;John, Sally L.;Potter, Catherine;Silman, Alan J.;Symmons, Deborah P. M.;Thomson, Wendy;Worthington, Jane;Clayton, David G.;Dunger, David B.;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Widmer, Barry;Todd, John A.;Frayling, Timothy M.;Freathy, Rachel M.;Lango, Hana;Perry, John R. B.;Shields, Beverley M.;Weedon, Michael N.;Hattersley, Andrew T.;Hitman, Graham A.;Walker, Mark;Elliott, Kate S.;Groves, Christopher J.;Lindgren, Cecilia M.;Rayner, Nigel W.;Timpson, Nicholas J.;Zeggini, Eleftheria;McCarthy, Mark I.;Newport, Melanie;Sirugo, Giorgio;Lyons, Emily;Vannberg, Fredrik;Hill, Adrian V. S.;Bradbury, Linda A.;Farrar, Claire;Pointon, Jennifer J.;Wordsworth, Paul;Brown, Matthew A.;Franklyn, Jayne A.;Heward, Joanne M.;Simmonds, Matthew J.;Gough, Stephen C. L.;Seal, Sheila;Stratton, Michael R.;Rahman, Nazneen;Ban, Maria;Goris, An;Sawcer, Stephen J.;Compston, Alastair;Conway, David;Jallow, Muminatou;Newport, Melanie;Sirugo, Giorgio;Rockett, Kirk A.;Kwiatkowski, Dominic P.;Bryan, Claire;Bumpstead, Suzannah J.;Chaney, Amy;Downes, Kate;Ghori, Jilur;Gwilliam, Rhian;Hunt, Sarah E.;Inouye, Michael;Keniry, Andrew;King, Emma;McGinnis, Ralph;Potter, Simon;Ravindrarajah, Rathi;Whittaker, Pamela;Withers, David;Deloukas, Panos;Leung, Hin-Tak;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Todd, John A.;Easton, Doug;Clayton, David G.;Burton, Paul R.;Tobin, Martin D.;Barrett, Jeffrey C.;Evans, David;Morris, Andrew P.;Cardon, Lon R.;Cardin, Niall J.;Davison, Dan;Ferreira, Teresa;Pereira-Gale, Joanne;Hallgrimsdóttir, Ingeleif B.;Howie, Bryan N.;Marchini, Jonathan L.;Spencer, Chris C. A.;Su, Zhan;Ying Teo, Yik;Vukcevic, Damjan;Donnelly, Peter;Bentley, David;Brown, Matthew A.;Cardon, Lon R.;Caulfield, Mark;Clayton, David G.;Compston, Alistair;Craddock, Nick;Deloukas, Panos;Donnelly, Peter;Farrall, Martin;Gough, Stephen C. L.;Hall, Alistair S.;Hattersley, Andrew T.;Hill, Adrian V. S.;Kwiatkowski, Dominic P.;Mathew, Christopher G.;McCarthy, Mark I.;Ouwehand, Willem H.;Parkes, Miles;Pembrey, Marcus;Rahman, Nazneen;Samani, Nilesh J.;Stratton, Michael R.;Todd, John A.;Worthington, Jane
The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. In type 1 diabetes the major gene...
Imputation using external reference panels is a widely used approach for increasing power in GWAS and meta-analysis. Existing HMM-based imputation approaches require individual-level genotypes. Here, we develop a new method for Gaussian imputation fr...