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Title
OBJECTIVE: Observational evidence supports independent associations of 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) with cardiovascular risk. A plausible hypothesis for these associations is accelerated development of atherosclerosis. A...
OBJECTIVE: Observational evidence supports independent associations of 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) with cardiovascular risk. A plausible hypothesis for these associations is accelerated development of atherosclerosis. A...
OBJECTIVE: Observational evidence supports independent associations of 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) with cardiovascular risk. A plausible hypothesis for these associations is accelerated development of atherosclerosis. A...
OBJECTIVE: Observational evidence supports independent associations of 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) with cardiovascular risk. A plausible hypothesis for these associations is accelerated development of atherosclerosis. A...
Holmes, Michael V;Dale, Caroline E;Zuccolo, Luisa;Silverwood, Richard J;Guo, Yiran;Ye, Zheng;Prieto-Merino, David;Dehghan, Abbas;Trompet, Stella;Wong, Andrew;Cavadino, Alana;Drogan, Dagmar;Padmanabhan, Sandosh;Li, Shanshan;Yesupriya, Ajay;Leusink, Maarten;Sundstrom, Johan;Hubacek, Jaroslav A;Pikhart, Hynek;Swerdlow, Daniel I;Panayiotou, Andrie G;Borinskaya, Svetlana A;Finan, Chris;Shah, Sonia;Kuchenbaecker, Karoline Bernhardine;Shah, Tina;Engmann, Jorgen;Folkersen, Lasse;Eriksson, Per;Ricceri, Fulvio;Melander, Olle;Sacerdote, Carlotta;Gamble, Dale M;Rayaprolu, Sruti;Ross, Owen A;McLachlan, Stela;Vikhireva, Olga;Sluijs, Ivonne;Scott, Robert;Adamkova, Vera;Flicker, Leon;Bockxmeer, Frank M van;Power, Christine;Marques-Vidal, Pedro;Meade, Tom;Marmot, Michael G;Ferro, Jose M;Paulos-Pinheiro, Sofia;Humphries, Steve E;Talmud, Philippa J;Mateo Leach, Irene;Verweij, Niek;Linneberg, Allan;Skaaby, Tea;Doevendans, Pieter A;Cramer, Maarten J;van der Harst, Pim;Klungel, Olaf H;Dowling, Nicole F;Dominiczak, Anna F;Kumari, Meena;Nicolaides, Andrew N;Weikert, Cornelia;Boeing, Heiner;Ebrahim, Shah;Gaunt, Tom R;Price, Jackie F;Lannfelt, Lars;Peasey, Anne;Kubinova, Ruzena;Pajak, Andrzej;Malyutina, Sofia;Voevoda, Mikhail I;Tamosiunas, Abdonas;Maitland-van der Zee, Anke H;Norman, Paul E;Hankey, Graeme J;Bergmann, Manuela M;Hofman, Albert;Franco, Oscar H;Cooper, Jackie;Palmen, Jutta;Spiering, Wilko;de Jong, Pim A;Kuh, Diana;Hardy, Rebecca;Uitterlinden, Andre G;Ikram, M Arfan;Ford, Ian;Hyppönen, Elina;Almeida, Osvaldo P;Wareham, Nicholas John;Khaw, Kay-Tee;Hamsten, Anders;Husemoen, Lise Lotte N;Tjønneland, Anne;Tolstrup, Janne S;Rimm, Eric;Beulens, Joline WJ;Verschuren, WM Monique;Onland-Moret, N Charlotte;Hofker, Marten H;Wannamethee, S Goya;Whincup, Peter H;Morris, Richard;Vicente, Astrid M;Watkins, Hugh;Farrall, Martin;Jukema, J Wouter;Meschia, James;Cupples, L Adrienne;Sharp, Stephen John;Fornage, Myriam;Kooperberg, Charles;LaCroix, Andrea Z;Dai, James Y;Lanktree, Matthew B;Siscovick, David S;Jorgenson, Eric;Spring, Bonnie;Coresh, Josef;Li, Yun R;Buxbaum, Sarah G;Schreiner, Pamela J;Ellison, R Curtis;Tsai, Michael Y;Patel, Sanjay R;Redline, Susan;Johnson, Andrew D;Hoogeveen, Ron C;Hakonarson, Hakon;Rotter, Jerome I;Boerwinkle, Eric;de Bakker, Paul IW;Kivimaki, Mika;Asselbergs, Folkert W;Sattar, Naveed;Lawlor, Debbie A;Whittaker, John;Davey Smith, George;Mukamal, Kenneth;Psaty, Bruce M;Wilson, James G;Lange, Leslie A;Hamidovic, Ajna;Hingorani, Aroon D;Nordestgaard, Børge G;Bobak, Martin;Leon, David A;Langenberg, Claudia;Palmer, Tom M;Reiner, Alex P;Keating, Brendan J;Dudbridge, Frank;Casas, Juan P;InterAct Consortium,
OBJECTIVE: To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. DESIGN: Mendelian randomisation meta-analysis of 56 epidemiological studies. PA...
OBJECTIVE: Observational evidence supports independent associations of 25-hydroxyvitamin D (25-OHD) and parathyroid hormone (PTH) with cardiovascular risk. A plausible hypothesis for these associations is accelerated development of atherosclerosis. A...
Holmes, Michael V;Dale, Caroline E;Zuccolo, Luisa;Silverwood, Richard J;Guo, Yiran;Ye, Zheng;Prieto-Merino, David;Dehghan, Abbas;Trompet, Stella;Wong, Andrew;Cavadino, Alana;Drogan, Dagmar;Padmanabhan, Sandosh;Li, Shanshan;Yesupriya, Ajay;Leusink, Maarten;Sundstrom, Johan;Hubacek, Jaroslav A;Pikhart, Hynek;Swerdlow, Daniel I;Panayiotou, Andrie G;Borinskaya, Svetlana A;Finan, Chris;Shah, Sonia;Kuchenbaecker, Karoline Bernhardine;Shah, Tina;Engmann, Jorgen;Folkersen, Lasse;Eriksson, Per;Ricceri, Fulvio;Melander, Olle;Sacerdote, Carlotta;Gamble, Dale M;Rayaprolu, Sruti;Ross, Owen A;McLachlan, Stela;Vikhireva, Olga;Sluijs, Ivonne;Scott, Robert;Adamkova, Vera;Flicker, Leon;Bockxmeer, Frank M van;Power, Christine;Marques-Vidal, Pedro;Meade, Tom;Marmot, Michael G;Ferro, Jose M;Paulos-Pinheiro, Sofia;Humphries, Steve E;Talmud, Philippa J;Mateo Leach, Irene;Verweij, Niek;Linneberg, Allan;Skaaby, Tea;Doevendans, Pieter A;Cramer, Maarten J;van der Harst, Pim;Klungel, Olaf H;Dowling, Nicole F;Dominiczak, Anna F;Kumari, Meena;Nicolaides, Andrew N;Weikert, Cornelia;Boeing, Heiner;Ebrahim, Shah;Gaunt, Tom R;Price, Jackie F;Lannfelt, Lars;Peasey, Anne;Kubinova, Ruzena;Pajak, Andrzej;Malyutina, Sofia;Voevoda, Mikhail I;Tamosiunas, Abdonas;Maitland-van der Zee, Anke H;Norman, Paul E;Hankey, Graeme J;Bergmann, Manuela M;Hofman, Albert;Franco, Oscar H;Cooper, Jackie;Palmen, Jutta;Spiering, Wilko;de Jong, Pim A;Kuh, Diana;Hardy, Rebecca;Uitterlinden, Andre G;Ikram, M Arfan;Ford, Ian;Hyppönen, Elina;Almeida, Osvaldo P;Wareham, Nicholas John;Khaw, Kay-Tee;Hamsten, Anders;Husemoen, Lise Lotte N;Tjønneland, Anne;Tolstrup, Janne S;Rimm, Eric;Beulens, Joline WJ;Verschuren, WM Monique;Onland-Moret, N Charlotte;Hofker, Marten H;Wannamethee, S Goya;Whincup, Peter H;Morris, Richard;Vicente, Astrid M;Watkins, Hugh;Farrall, Martin;Jukema, J Wouter;Meschia, James;Cupples, L Adrienne;Sharp, Stephen John;Fornage, Myriam;Kooperberg, Charles;LaCroix, Andrea Z;Dai, James Y;Lanktree, Matthew B;Siscovick, David S;Jorgenson, Eric;Spring, Bonnie;Coresh, Josef;Li, Yun R;Buxbaum, Sarah G;Schreiner, Pamela J;Ellison, R Curtis;Tsai, Michael Y;Patel, Sanjay R;Redline, Susan;Johnson, Andrew D;Hoogeveen, Ron C;Hakonarson, Hakon;Rotter, Jerome I;Boerwinkle, Eric;de Bakker, Paul IW;Kivimaki, Mika;Asselbergs, Folkert W;Sattar, Naveed;Lawlor, Debbie A;Whittaker, John;Davey Smith, George;Mukamal, Kenneth;Psaty, Bruce M;Wilson, James G;Lange, Leslie A;Hamidovic, Ajna;Hingorani, Aroon D;Nordestgaard, Børge G;Bobak, Martin;Leon, David A;Langenberg, Claudia;Palmer, Tom M;Reiner, Alex P;Keating, Brendan J;Dudbridge, Frank;Casas, Juan P;InterAct Consortium,
OBJECTIVE: To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. DESIGN: Mendelian randomisation meta-analysis of 56 epidemiological studies. PA...
Background: Odd-numbered chain saturated fatty acids (OCSFA) have been associated with potential health benefits. Although some OCSFA (e.g., C15:0 and C17:0) are found in meats and dairy products, sources and metabolism of C19:0 and C23:0 are relativ...
Background: Environments conducive to walking may help people avoid sedentary lifestyles and associated diseases. Recent studies developed walkability models combining several built environment characteristics to optimally predict walking. Developing...
Wheeler, Eleanor;Leong, Aaron;Liu, Ching-Ti;Hivert, Marie-France;Strawbridge, Rona J.;Podmore, Clara;Li, Man;Yao, Jie;Sim, Xueling;Hong, Jaeyoung;Chu, Audrey Y.;Zhang, Weihua;Wang, Xu;Chen, Peng;Maruthur, Nisa M.;Porneala, Bianca C.;Sharp, Stephen J.;Jia, Yucheng;Kabagambe, Edmond K.;Chang, Li-Ching;Chen, Wei-Min;Elks, Cathy E.;Evans, Daniel S.;Fan, Qiao;Giulianini, Franco;Go, Min Jin;Hottenga, Jouke-Jan;Hu, Yao;Jackson, Anne U.;Kanoni, Stavroula;Kim, Young Jin;Kleber, Marcus E.;Ladenvall, Claes;Lecoeur, Cecile;Lim, Sing-Hui;Lu, Yingchang;Mahajan, Anubha;Marzi, Carola;Nalls, Mike A.;Navarro, Pau;Nolte, Ilja M.;Rose, Lynda M.;Rybin, Denis V.;Sanna, Serena;Shi, Yuan;Stram, Daniel O.;Takeuchi, Fumihiko;Tan, Shu Pei;van der Most, Peter J.;Van Vliet-Ostaptchouk, Jana V.;Wong, Andrew;Yengo, Loic;Zhao, Wanting;Goel, Anuj;Martinez Larrad, Maria Teresa;Radke, Dörte;Salo, Perttu;Tanaka, Toshiko;van Iperen, Erik P. A.;Abecasis, Goncalo;Afaq, Saima;Alizadeh, Behrooz Z.;Bertoni, Alain G.;Bonnefond, Amelie;Böttcher, Yvonne;Bottinger, Erwin P.;Campbell, Harry;Carlson, Olga D.;Chen, Chien-Hsiun;Cho, Yoon Shin;Garvey, W. Timothy;Gieger, Christian;Goodarzi, Mark O.;Grallert, Harald;Hamsten, Anders;Hartman, Catharina A.;Herder, Christian;Hsiung, Chao Agnes;Huang, Jie;Igase, Michiya;Isono, Masato;Katsuya, Tomohiro;Khor, Chiea-Chuen;Kiess, Wieland;Kohara, Katsuhiko;Kovacs, Peter;Lee, Juyoung;Lee, Wen-Jane;Lehne, Benjamin;Li, Huaixing;Liu, Jianjun;Lobbens, Stephane;Luan, Jian'an;Lyssenko, Valeriya;Meitinger, Thomas;Miki, Tetsuro;Miljkovic, Iva;Moon, Sanghoon;Mulas, Antonella;Müller, Gabriele;Müller-Nurasyid, Martina;Nagaraja, Ramaiah;Nauck, Matthias;Pankow, James S.;Polasek, Ozren;Prokopenko, Inga;Ramos, Paula S.;Rasmussen-Torvik, Laura;Rathmann, Wolfgang;Rich, Stephen S.;Robertson, Neil R.;Roden, Michael;Roussel, Ronan;Rudan, Igor;Scott, Robert A.;Scott, William R.;Sennblad, Bengt;Siscovick, David S.;Strauch, Konstantin;Sun, Liang;Swertz, Morris;Tajuddin, Salman M.;Taylor, Kent D.;Teo, Yik-Ying;Tham, Yih Chung;Tönjes, Anke;Wareham, Nicholas J.;Willemsen, Gonneke;Wilsgaard, Tom;Hingorani, Aroon D.;Egan, Josephine;Ferrucci, Luigi;Hovingh, G. Kees;Jula, Antti;Kivimaki, Mika;Kumari, Meena;Njølstad, Inger;Palmer, Colin N. A.;Serrano Ríos, Manuel;Stumvoll, Michael;Watkins, Hugh;Aung, Tin;Blüher, Matthias;Boehnke, Michael;Boomsma, Dorret I.;Bornstein, Stefan R.;Chambers, John C.;Chasman, Daniel I.;Chen, Yii-Der Ida;Chen, Yduan-Tsong;Cheng, Ching-Yu;Cucca, Francesco;de Geus, Eco J. C.;Deloukas, Panos;Evans, Michele K.;Fornage, Myriam;Friedlander, Yechiel;Froguel, Philippe;Groop, Leif;Gross, Myron D.;Harris, Tamara B.;Hayward, Caroline;Heng, Chew-Kiat;Ingelsson, Erik;Kato, Norihiro;Kim, Bong-Jo;Koh, Woon-Puay;Kooner, Jaspal S.;Körner, Antje;Kuh, Diana;Kuusisto, Johanna;Laakso, Markku;Lin, Xu;Liu, Yongmei;Loos, Ruth J. F.;Magnusson, Patrik K. E.;März, Winfried;McCarthy, Mark I.;Oldehinkel, Albertine J.;Ong, Ken K.;Pedersen, Nancy L.;Pereira, Mark A.;Peters, Annette;Ridker, Paul M.;Sabanayagam, Charumathi;Sale, Michele;Saleheen, Danish;Saltevo, Juha;Schwarz, Peter EH.;Sheu, Wayne H. H.;Snieder, Harold;Spector, Timothy D.;Tabara, Yasuharu;Tuomilehto, Jaakko;van Dam, Rob M.;Wilson, James G.;Wilson, James F.;Wolffenbuttel, Bruce H. R.;Wong, Tien Yin;Wu, Jer-Yuarn;Yuan, Jian-Min;Zonderman, Alan B.;Soranzo, Nicole;Guo, Xiuqing;Roberts, David J.;Florez, Jose C.;Sladek, Robert;Dupuis, Josée;Morris, Andrew P.;Tai, E-Shyong;Selvin, Elizabeth;Rotter, Jerome I.;Langenberg, Claudia;Barroso, Inês;Meigs, James B.
Background: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These varia...