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Document(s)
Title
Little is known regarding the epigenetic basis of atherosclerosis. Here we present the CD14+ blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis. The transcriptome signature includes transcription coactivator, ...
Little is known regarding the epigenetic basis of atherosclerosis. Here we present the CD14+ blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis. The transcriptome signature includes transcription coactivator, ...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios;LifeLines Cohort Study
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Holmes, Michael V;Dale, Caroline E;Zuccolo, Luisa;Silverwood, Richard J;Guo, Yiran;Ye, Zheng;Prieto-Merino, David;Dehghan, Abbas;Trompet, Stella;Wong, Andrew;Cavadino, Alana;Drogan, Dagmar;Padmanabhan, Sandosh;Li, Shanshan;Yesupriya, Ajay;Leusink, Maarten;Sundstrom, Johan;Hubacek, Jaroslav A;Pikhart, Hynek;Swerdlow, Daniel I;Panayiotou, Andrie G;Borinskaya, Svetlana A;Finan, Chris;Shah, Sonia;Kuchenbaecker, Karoline Bernhardine;Shah, Tina;Engmann, Jorgen;Folkersen, Lasse;Eriksson, Per;Ricceri, Fulvio;Melander, Olle;Sacerdote, Carlotta;Gamble, Dale M;Rayaprolu, Sruti;Ross, Owen A;McLachlan, Stela;Vikhireva, Olga;Sluijs, Ivonne;Scott, Robert;Adamkova, Vera;Flicker, Leon;Bockxmeer, Frank M van;Power, Christine;Marques-Vidal, Pedro;Meade, Tom;Marmot, Michael G;Ferro, Jose M;Paulos-Pinheiro, Sofia;Humphries, Steve E;Talmud, Philippa J;Mateo Leach, Irene;Verweij, Niek;Linneberg, Allan;Skaaby, Tea;Doevendans, Pieter A;Cramer, Maarten J;van der Harst, Pim;Klungel, Olaf H;Dowling, Nicole F;Dominiczak, Anna F;Kumari, Meena;Nicolaides, Andrew N;Weikert, Cornelia;Boeing, Heiner;Ebrahim, Shah;Gaunt, Tom R;Price, Jackie F;Lannfelt, Lars;Peasey, Anne;Kubinova, Ruzena;Pajak, Andrzej;Malyutina, Sofia;Voevoda, Mikhail I;Tamosiunas, Abdonas;Maitland-van der Zee, Anke H;Norman, Paul E;Hankey, Graeme J;Bergmann, Manuela M;Hofman, Albert;Franco, Oscar H;Cooper, Jackie;Palmen, Jutta;Spiering, Wilko;de Jong, Pim A;Kuh, Diana;Hardy, Rebecca;Uitterlinden, Andre G;Ikram, M Arfan;Ford, Ian;Hyppönen, Elina;Almeida, Osvaldo P;Wareham, Nicholas John;Khaw, Kay-Tee;Hamsten, Anders;Husemoen, Lise Lotte N;Tjønneland, Anne;Tolstrup, Janne S;Rimm, Eric;Beulens, Joline WJ;Verschuren, WM Monique;Onland-Moret, N Charlotte;Hofker, Marten H;Wannamethee, S Goya;Whincup, Peter H;Morris, Richard;Vicente, Astrid M;Watkins, Hugh;Farrall, Martin;Jukema, J Wouter;Meschia, James;Cupples, L Adrienne;Sharp, Stephen John;Fornage, Myriam;Kooperberg, Charles;LaCroix, Andrea Z;Dai, James Y;Lanktree, Matthew B;Siscovick, David S;Jorgenson, Eric;Spring, Bonnie;Coresh, Josef;Li, Yun R;Buxbaum, Sarah G;Schreiner, Pamela J;Ellison, R Curtis;Tsai, Michael Y;Patel, Sanjay R;Redline, Susan;Johnson, Andrew D;Hoogeveen, Ron C;Hakonarson, Hakon;Rotter, Jerome I;Boerwinkle, Eric;de Bakker, Paul IW;Kivimaki, Mika;Asselbergs, Folkert W;Sattar, Naveed;Lawlor, Debbie A;Whittaker, John;Davey Smith, George;Mukamal, Kenneth;Psaty, Bruce M;Wilson, James G;Lange, Leslie A;Hamidovic, Ajna;Hingorani, Aroon D;Nordestgaard, Børge G;Bobak, Martin;Leon, David A;Langenberg, Claudia;Palmer, Tom M;Reiner, Alex P;Keating, Brendan J;Dudbridge, Frank;Casas, Juan P;InterAct Consortium,
OBJECTIVE: To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. DESIGN: Mendelian randomisation meta-analysis of 56 epidemiological studies. PA...
Holmes, Michael V;Dale, Caroline E;Zuccolo, Luisa;Silverwood, Richard J;Guo, Yiran;Ye, Zheng;Prieto-Merino, David;Dehghan, Abbas;Trompet, Stella;Wong, Andrew;Cavadino, Alana;Drogan, Dagmar;Padmanabhan, Sandosh;Li, Shanshan;Yesupriya, Ajay;Leusink, Maarten;Sundstrom, Johan;Hubacek, Jaroslav A;Pikhart, Hynek;Swerdlow, Daniel I;Panayiotou, Andrie G;Borinskaya, Svetlana A;Finan, Chris;Shah, Sonia;Kuchenbaecker, Karoline Bernhardine;Shah, Tina;Engmann, Jorgen;Folkersen, Lasse;Eriksson, Per;Ricceri, Fulvio;Melander, Olle;Sacerdote, Carlotta;Gamble, Dale M;Rayaprolu, Sruti;Ross, Owen A;McLachlan, Stela;Vikhireva, Olga;Sluijs, Ivonne;Scott, Robert;Adamkova, Vera;Flicker, Leon;Bockxmeer, Frank M van;Power, Christine;Marques-Vidal, Pedro;Meade, Tom;Marmot, Michael G;Ferro, Jose M;Paulos-Pinheiro, Sofia;Humphries, Steve E;Talmud, Philippa J;Mateo Leach, Irene;Verweij, Niek;Linneberg, Allan;Skaaby, Tea;Doevendans, Pieter A;Cramer, Maarten J;van der Harst, Pim;Klungel, Olaf H;Dowling, Nicole F;Dominiczak, Anna F;Kumari, Meena;Nicolaides, Andrew N;Weikert, Cornelia;Boeing, Heiner;Ebrahim, Shah;Gaunt, Tom R;Price, Jackie F;Lannfelt, Lars;Peasey, Anne;Kubinova, Ruzena;Pajak, Andrzej;Malyutina, Sofia;Voevoda, Mikhail I;Tamosiunas, Abdonas;Maitland-van der Zee, Anke H;Norman, Paul E;Hankey, Graeme J;Bergmann, Manuela M;Hofman, Albert;Franco, Oscar H;Cooper, Jackie;Palmen, Jutta;Spiering, Wilko;de Jong, Pim A;Kuh, Diana;Hardy, Rebecca;Uitterlinden, Andre G;Ikram, M Arfan;Ford, Ian;Hyppönen, Elina;Almeida, Osvaldo P;Wareham, Nicholas John;Khaw, Kay-Tee;Hamsten, Anders;Husemoen, Lise Lotte N;Tjønneland, Anne;Tolstrup, Janne S;Rimm, Eric;Beulens, Joline WJ;Verschuren, WM Monique;Onland-Moret, N Charlotte;Hofker, Marten H;Wannamethee, S Goya;Whincup, Peter H;Morris, Richard;Vicente, Astrid M;Watkins, Hugh;Farrall, Martin;Jukema, J Wouter;Meschia, James;Cupples, L Adrienne;Sharp, Stephen John;Fornage, Myriam;Kooperberg, Charles;LaCroix, Andrea Z;Dai, James Y;Lanktree, Matthew B;Siscovick, David S;Jorgenson, Eric;Spring, Bonnie;Coresh, Josef;Li, Yun R;Buxbaum, Sarah G;Schreiner, Pamela J;Ellison, R Curtis;Tsai, Michael Y;Patel, Sanjay R;Redline, Susan;Johnson, Andrew D;Hoogeveen, Ron C;Hakonarson, Hakon;Rotter, Jerome I;Boerwinkle, Eric;de Bakker, Paul IW;Kivimaki, Mika;Asselbergs, Folkert W;Sattar, Naveed;Lawlor, Debbie A;Whittaker, John;Davey Smith, George;Mukamal, Kenneth;Psaty, Bruce M;Wilson, James G;Lange, Leslie A;Hamidovic, Ajna;Hingorani, Aroon D;Nordestgaard, Børge G;Bobak, Martin;Leon, David A;Langenberg, Claudia;Palmer, Tom M;Reiner, Alex P;Keating, Brendan J;Dudbridge, Frank;Casas, Juan P;InterAct Consortium,
OBJECTIVE: To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. DESIGN: Mendelian randomisation meta-analysis of 56 epidemiological studies. PA...
Feitosa, Mary F.;Kraja, Aldi T.;Chasman, Daniel I.;Sung, Yun J.;Winkler, Thomas W.;Ntalla, Ioanna;Guo, Xiuqing;Franceschini, Nora;Cheng, Ching-Yu;Sim, Xueling;Vojinovic, Dina;Marten, Jonathan;Musani, Solomon K.;Li, Changwei;Bentley, Amy R.;Brown, Michael R.;Schwander, Karen;Richard, Melissa A.;Noordam, Raymond;Aschard, Hugues;Bartz, Traci M.;Bielak, Lawrence F.;Dorajoo, Rajkumar;Fisher, Virginia;Hartwig, Fernando P.;Horimoto, Andrea R. V. R.;Lohman, Kurt K.;Manning, Alisa K.;Rankinen, Tuomo;Smith, Albert V.;Tajuddin, Salman M.;Wojczynski, Mary K.;Alver, Maris;Boissel, Mathilde;Cai, Qiuyin;Campbell, Archie;Chai, Jin Fang;Chen, Xu;Divers, Jasmin;Gao, Chuan;Goel, Anuj;Hagemeijer, Yanick;Harris, Sarah E.;He, Meian;Hsu, Fang-Chi;Jackson, Anne U.;Kähönen, Mika;Kasturiratne, Anuradhani;Komulainen, Pirjo;Kühnel, Brigitte;Laguzzi, Federica;Luan, Jian'an;Matoba, Nana;Nolte, Ilja M.;Padmanabhan, Sandosh;Riaz, Muhammad;Rueedi, Rico;Robino, Antonietta;Said, M. Abdullah;Scott, Robert A.;Sofer, Tamar;Stančáková, Alena;Takeuchi, Fumihiko;Tayo, Bamidele O.;van der Most, Peter J.;Varga, Tibor V.;Vitart, Veronique;Wang, Yajuan;Ware, Erin B.;Warren, Helen R.;Weiss, Stefan;Wen, Wanqing;Yanek, Lisa R.;Zhang, Weihua;Zhao, Jing Hua;Afaq, Saima;Amin, Najaf;Amini, Marzyeh;Arking, Dan E.;Aung, Tin;Boerwinkle, Eric;Borecki, Ingrid;Broeckel, Ulrich;Brown, Morris;Brumat, Marco;Burke, Gregory L.;Canouil, Mickaël;Chakravarti, Aravinda;Charumathi, Sabanayagam;Ida Chen, Yii-Der;Connell, John M.;Correa, Adolfo;de las Fuentes, Lisa;de Mutsert, Renée;de Silva, H. Janaka;Deng, Xuan;Ding, Jingzhong;Duan, Qing;Eaton, Charles B.;Ehret, Georg;Eppinga, Ruben N.;Evangelou, Evangelos;Faul, Jessica D.;Felix, Stephan B.;Forouhi, Nita G.;Forrester, Terrence;Franco, Oscar H.;Friedlander, Yechiel;Gandin, Ilaria;Gao, He;Ghanbari, Mohsen;Gigante, Bruna;Gu, C. Charles;Gu, Dongfeng;Hagenaars, Saskia P.;Hallmans, Göran;Harris, Tamara B.;He, Jiang;Heikkinen, Sami;Heng, Chew-Kiat;Hirata, Makoto;Howard, Barbara V.;Ikram, M. Arfan;John, Ulrich;Katsuya, Tomohiro;Khor, Chiea Chuen;Kilpeläinen, Tuomas O.;Koh, Woon-Puay;Krieger, José E.;Kritchevsky, Stephen B.;Kubo, Michiaki;Kuusisto, Johanna;Lakka, Timo A.;Langefeld, Carl D.;Langenberg, Claudia;Launer, Lenore J.;Lehne, Benjamin;Lewis, Cora E.;Li, Yize;Lin, Shiow;Liu, Jianjun;Liu, Jingmin;Loh, Marie;Louie, Tin;Mägi, Reedik;McKenzie, Colin A.;Meitinger, Thomas;Metspalu, Andres;Milaneschi, Yuri;Milani, Lili;Mohlke, Karen L.;Momozawa, Yukihide;Nalls, Mike A.;Nelson, Christopher P.;Sotoodehnia, Nona;Norris, Jill M.;O'Connell, Jeff R.;Palmer, Nicholette D.;Perls, Thomas;Pedersen, Nancy L.;Peters, Annette;Peyser, Patricia A.;Poulter, Neil;Raffel, Leslie J.;Raitakari, Olli T.;Roll, Kathryn;Rose, Lynda M.;Rosendaal, Frits R.;Rotter, Jerome I.;Schmidt, Carsten O.;Schreiner, Pamela J.;Schupf, Nicole;Scott, William R.;Sever, Peter S.;Shi, Yuan;Sidney, Stephen;Sims, Mario;Sitlani, Colleen M.;Smith, Jennifer A.;Snieder, Harold;Starr, John M.;Strauch, Konstantin;Stringham, Heather M.;Tan, Nicholas Y. Q.;Tang, Hua;Taylor, Kent D.;Teo, Yik Ying;Tham, Yih Chung;Turner, Stephen T.;Uitterlinden, André G.;Vollenweider, Peter;Waldenberger, Melanie;Wang, Lihua;Wang, Ya Xing;Wei, Wen Bin;Williams, Christine;Yao, Jie;Yu, Caizheng;Yuan, Jian-Min;Zhao, Wei;Zonderman, Alan B.;Becker, Diane M.;Boehnke, Michael;Bowden, Donald W.;Chambers, John C.;Deary, Ian J.;Esko, Tõnu;Farrall, Martin;Franks, Paul W.;Freedman, Barry I.;Froguel, Philippe;Gasparini, Paolo;Gieger, Christian;Jonas, Jost Bruno;Kamatani, Yoichiro;Kato, Norihiro;Kooner, Jaspal S.;Kutalik, Zoltán;Laakso, Markku;Laurie, Cathy C.;Leander, Karin;Lehtimäki, Terho;Study, Lifelines Cohort;Magnusson, Patrik K. E.;Oldehinkel, Albertine J.;Penninx, Brenda W. J. H.;Polasek, Ozren;Porteous, David J.;Rauramaa, Rainer;Samani, Nilesh J.;Scott, James;Shu, Xiao-Ou;van der Harst, Pim;Wagenknecht, Lynne E.;Wareham, Nicholas J.;Watkins, Hugh;Weir, David R.;Wickremasinghe, Ananda R.;Wu, Tangchun;Zheng, Wei;Bouchard, Claude;Christensen, Kaare;Evans, Michele K.;Gudnason, Vilmundur;Horta, Bernardo L.;Kardia, Sharon L. R.;Liu, Yongmei;Pereira, Alexandre C.;Psaty, Bruce M.;Ridker, Paul M.;van Dam, Rob M.;Gauderman, W. James;Zhu, Xiaofeng;Mook-Kanamori, Dennis O.;Fornage, Myriam;Rotimi, Charles N.;Cupples, L. Adrienne;Kelly, Tanika N.;Fox, Ervin R.;Hayward, Caroline;van Duijn, Cornelia M.;Tai, E Shyong;Wong, Tien Yin;Kooperberg, Charles;Palmas, Walter;Rice, Kenneth;Morrison, Alanna C.;Elliott, Paul;Caulfield, Mark J.;Munroe, Patricia B.;Rao, Dabeeru C.;Province, Michael A.;Levy, Daniel
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcoh...
Feitosa, Mary F.;Kraja, Aldi T.;Chasman, Daniel I.;Sung, Yun J.;Winkler, Thomas W.;Ntalla, Ioanna;Guo, Xiuqing;Franceschini, Nora;Cheng, Ching-Yu;Sim, Xueling;Vojinovic, Dina;Marten, Jonathan;Musani, Solomon K.;Li, Changwei;Bentley, Amy R.;Brown, Michael R.;Schwander, Karen;Richard, Melissa A.;Noordam, Raymond;Aschard, Hugues;Bartz, Traci M.;Bielak, Lawrence F.;Dorajoo, Rajkumar;Fisher, Virginia;Hartwig, Fernando P.;Horimoto, Andrea R. V. R.;Lohman, Kurt K.;Manning, Alisa K.;Rankinen, Tuomo;Smith, Albert V.;Tajuddin, Salman M.;Wojczynski, Mary K.;Alver, Maris;Boissel, Mathilde;Cai, Qiuyin;Campbell, Archie;Chai, Jin Fang;Chen, Xu;Divers, Jasmin;Gao, Chuan;Goel, Anuj;Hagemeijer, Yanick;Harris, Sarah E.;He, Meian;Hsu, Fang-Chi;Jackson, Anne U.;Kähönen, Mika;Kasturiratne, Anuradhani;Komulainen, Pirjo;Kühnel, Brigitte;Laguzzi, Federica;Luan, Jian'an;Matoba, Nana;Nolte, Ilja M.;Padmanabhan, Sandosh;Riaz, Muhammad;Rueedi, Rico;Robino, Antonietta;Said, M. Abdullah;Scott, Robert A.;Sofer, Tamar;Stančáková, Alena;Takeuchi, Fumihiko;Tayo, Bamidele O.;van der Most, Peter J.;Varga, Tibor V.;Vitart, Veronique;Wang, Yajuan;Ware, Erin B.;Warren, Helen R.;Weiss, Stefan;Wen, Wanqing;Yanek, Lisa R.;Zhang, Weihua;Zhao, Jing Hua;Afaq, Saima;Amin, Najaf;Amini, Marzyeh;Arking, Dan E.;Aung, Tin;Boerwinkle, Eric;Borecki, Ingrid;Broeckel, Ulrich;Brown, Morris;Brumat, Marco;Burke, Gregory L.;Canouil, Mickaël;Chakravarti, Aravinda;Charumathi, Sabanayagam;Ida Chen, Yii-Der;Connell, John M.;Correa, Adolfo;de las Fuentes, Lisa;de Mutsert, Renée;de Silva, H. Janaka;Deng, Xuan;Ding, Jingzhong;Duan, Qing;Eaton, Charles B.;Ehret, Georg;Eppinga, Ruben N.;Evangelou, Evangelos;Faul, Jessica D.;Felix, Stephan B.;Forouhi, Nita G.;Forrester, Terrence;Franco, Oscar H.;Friedlander, Yechiel;Gandin, Ilaria;Gao, He;Ghanbari, Mohsen;Gigante, Bruna;Gu, C. Charles;Gu, Dongfeng;Hagenaars, Saskia P.;Hallmans, Göran;Harris, Tamara B.;He, Jiang;Heikkinen, Sami;Heng, Chew-Kiat;Hirata, Makoto;Howard, Barbara V.;Ikram, M. Arfan;John, Ulrich;Katsuya, Tomohiro;Khor, Chiea Chuen;Kilpeläinen, Tuomas O.;Koh, Woon-Puay;Krieger, José E.;Kritchevsky, Stephen B.;Kubo, Michiaki;Kuusisto, Johanna;Lakka, Timo A.;Langefeld, Carl D.;Langenberg, Claudia;Launer, Lenore J.;Lehne, Benjamin;Lewis, Cora E.;Li, Yize;Lin, Shiow;Liu, Jianjun;Liu, Jingmin;Loh, Marie;Louie, Tin;Mägi, Reedik;McKenzie, Colin A.;Meitinger, Thomas;Metspalu, Andres;Milaneschi, Yuri;Milani, Lili;Mohlke, Karen L.;Momozawa, Yukihide;Nalls, Mike A.;Nelson, Christopher P.;Sotoodehnia, Nona;Norris, Jill M.;O'Connell, Jeff R.;Palmer, Nicholette D.;Perls, Thomas;Pedersen, Nancy L.;Peters, Annette;Peyser, Patricia A.;Poulter, Neil;Raffel, Leslie J.;Raitakari, Olli T.;Roll, Kathryn;Rose, Lynda M.;Rosendaal, Frits R.;Rotter, Jerome I.;Schmidt, Carsten O.;Schreiner, Pamela J.;Schupf, Nicole;Scott, William R.;Sever, Peter S.;Shi, Yuan;Sidney, Stephen;Sims, Mario;Sitlani, Colleen M.;Smith, Jennifer A.;Snieder, Harold;Starr, John M.;Strauch, Konstantin;Stringham, Heather M.;Tan, Nicholas Y. Q.;Tang, Hua;Taylor, Kent D.;Teo, Yik Ying;Tham, Yih Chung;Turner, Stephen T.;Uitterlinden, André G.;Vollenweider, Peter;Waldenberger, Melanie;Wang, Lihua;Wang, Ya Xing;Wei, Wen Bin;Williams, Christine;Yao, Jie;Yu, Caizheng;Yuan, Jian-Min;Zhao, Wei;Zonderman, Alan B.;Becker, Diane M.;Boehnke, Michael;Bowden, Donald W.;Chambers, John C.;Deary, Ian J.;Esko, Tõnu;Farrall, Martin;Franks, Paul W.;Freedman, Barry I.;Froguel, Philippe;Gasparini, Paolo;Gieger, Christian;Jonas, Jost Bruno;Kamatani, Yoichiro;Kato, Norihiro;Kooner, Jaspal S.;Kutalik, Zoltán;Laakso, Markku;Laurie, Cathy C.;Leander, Karin;Lehtimäki, Terho;Study, Lifelines Cohort;Magnusson, Patrik K. E.;Oldehinkel, Albertine J.;Penninx, Brenda W. J. H.;Polasek, Ozren;Porteous, David J.;Rauramaa, Rainer;Samani, Nilesh J.;Scott, James;Shu, Xiao-Ou;van der Harst, Pim;Wagenknecht, Lynne E.;Wareham, Nicholas J.;Watkins, Hugh;Weir, David R.;Wickremasinghe, Ananda R.;Wu, Tangchun;Zheng, Wei;Bouchard, Claude;Christensen, Kaare;Evans, Michele K.;Gudnason, Vilmundur;Horta, Bernardo L.;Kardia, Sharon L. R.;Liu, Yongmei;Pereira, Alexandre C.;Psaty, Bruce M.;Ridker, Paul M.;van Dam, Rob M.;Gauderman, W. James;Zhu, Xiaofeng;Mook-Kanamori, Dennis O.;Fornage, Myriam;Rotimi, Charles N.;Cupples, L. Adrienne;Kelly, Tanika N.;Fox, Ervin R.;Hayward, Caroline;van Duijn, Cornelia M.;Tai, E Shyong;Wong, Tien Yin;Kooperberg, Charles;Palmas, Walter;Rice, Kenneth;Morrison, Alanna C.;Elliott, Paul;Caulfield, Mark J.;Munroe, Patricia B.;Rao, Dabeeru C.;Province, Michael A.;Levy, Daniel
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcoh...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...