ARTICLES
7 Article(s)
Document(s)
Title
An increasing number of genome-wide association (GWA) studies are now using the higher resolution 1000 Genomes Project reference panel (1000G) for imputation, with the expectation that 1000G imputation will lead to the discovery of additional associa...
Ng, Maggie C. Y.;Graff, Mariaelisa;Lu, Yingchang;Justice, Anne E.;Mudgal, Poorva;Liu, Ching-Ti;Young, Kristin;Yanek, Lisa R.;Feitosa, Mary F.;Wojczynski, Mary K.;Rand, Kristin;Brody, Jennifer A.;Cade, Brian E.;Dimitrov, Latchezar;Duan, Qing;Guo, Xiuqing;Lange, Leslie A.;Nalls, Michael A.;Okut, Hayrettin;Tajuddin, Salman M.;Tayo, Bamidele O.;Vedantam, Sailaja;Bradfield, Jonathan P.;Chen, Guanjie;Chen, Wei-Min;Chesi, Alessandra;Irvin, Marguerite R.;Padhukasahasram, Badri;Smith, Jennifer A.;Zheng, Wei;Allison, Matthew A.;Ambrosone, Christine B.;Bandera, Elisa V.;Bartz, Traci M.;Berndt, Sonja I.;Bernstein, Leslie;Blot, William J.;Bottinger, Erwin P.;Carpten, John;Chanock, Stephen J.;Chen, Yii-Der Ida;Conti, David V.;Cooper, Richard S.;Fornage, Myriam;Freedman, Barry I.;Garcia, Melissa;Goodman, Phyllis J.;Hsu, Yu-Han H.;Hu, Jennifer;Huff, Chad D.;Ingles, Sue A.;John, Esther M.;Kittles, Rick;Klein, Eric;Li, Jin;McKnight, Barbara;Nayak, Uma;Nemesure, Barbara;Ogunniyi, Adesola;Olshan, Andrew;Press, Michael F.;Rohde, Rebecca;Rybicki, Benjamin A.;Salako, Babatunde;Sanderson, Maureen;Shao, Yaming;Siscovick, David S.;Stanford, Janet L.;Stevens, Victoria L.;Stram, Alex;Strom, Sara S.;Vaidya, Dhananjay;Witte, John S.;Yao, Jie;Zhu, Xiaofeng;Ziegler, Regina G.;Zonderman, Alan B.;Adeyemo, Adebowale;Ambs, Stefan;Cushman, Mary;Faul, Jessica D.;Hakonarson, Hakon;Levin, Albert M.;Nathanson, Katherine L.;Ware, Erin B.;Weir, David R.;Zhao, Wei;Zhi, Degui;Arnett, Donna K.;Grant, Struan F. A.;Kardia, Sharon L. R.;Oloapde, Olufunmilayo I.;Rao, D. C.;Rotimi, Charles N.;Sale, Michele M.;Williams, L. Keoki;Zemel, Babette S.;Becker, Diane M.;Borecki, Ingrid B.;Evans, Michele K.;Harris, Tamara B.;Hirschhorn, Joel N.;Li, Yun;Patel, Sanjay R.;Psaty, Bruce M.;Rotter, Jerome I.;Wilson, James G.;Bowden, Donald W.;Cupples, L. Adrienne;Haiman, Christopher A.;Loos, Ruth J. F.;North, Kari E.
Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African...
Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify...
Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify...
Ng, Maggie C. Y.;Graff, Mariaelisa;Lu, Yingchang;Justice, Anne E.;Mudgal, Poorva;Liu, Ching-Ti;Young, Kristin;Yanek, Lisa R.;Feitosa, Mary F.;Wojczynski, Mary K.;Rand, Kristin;Brody, Jennifer A.;Cade, Brian E.;Dimitrov, Latchezar;Duan, Qing;Guo, Xiuqing;Lange, Leslie A.;Nalls, Michael A.;Okut, Hayrettin;Tajuddin, Salman M.;Tayo, Bamidele O.;Vedantam, Sailaja;Bradfield, Jonathan P.;Chen, Guanjie;Chen, Wei-Min;Chesi, Alessandra;Irvin, Marguerite R.;Padhukasahasram, Badri;Smith, Jennifer A.;Zheng, Wei;Allison, Matthew A.;Ambrosone, Christine B.;Bandera, Elisa V.;Bartz, Traci M.;Berndt, Sonja I.;Bernstein, Leslie;Blot, William J.;Bottinger, Erwin P.;Carpten, John;Chanock, Stephen J.;Chen, Yii-Der Ida;Conti, David V.;Cooper, Richard S.;Fornage, Myriam;Freedman, Barry I.;Garcia, Melissa;Goodman, Phyllis J.;Hsu, Yu-Han H.;Hu, Jennifer;Huff, Chad D.;Ingles, Sue A.;John, Esther M.;Kittles, Rick;Klein, Eric;Li, Jin;McKnight, Barbara;Nayak, Uma;Nemesure, Barbara;Ogunniyi, Adesola;Olshan, Andrew;Press, Michael F.;Rohde, Rebecca;Rybicki, Benjamin A.;Salako, Babatunde;Sanderson, Maureen;Shao, Yaming;Siscovick, David S.;Stanford, Janet L.;Stevens, Victoria L.;Stram, Alex;Strom, Sara S.;Vaidya, Dhananjay;Witte, John S.;Yao, Jie;Zhu, Xiaofeng;Ziegler, Regina G.;Zonderman, Alan B.;Adeyemo, Adebowale;Ambs, Stefan;Cushman, Mary;Faul, Jessica D.;Hakonarson, Hakon;Levin, Albert M.;Nathanson, Katherine L.;Ware, Erin B.;Weir, David R.;Zhao, Wei;Zhi, Degui;Arnett, Donna K.;Grant, Struan F. A.;Kardia, Sharon L. R.;Oloapde, Olufunmilayo I.;Rao, D. C.;Rotimi, Charles N.;Sale, Michele M.;Williams, L. Keoki;Zemel, Babette S.;Becker, Diane M.;Borecki, Ingrid B.;Evans, Michele K.;Harris, Tamara B.;Hirschhorn, Joel N.;Li, Yun;Patel, Sanjay R.;Psaty, Bruce M.;Rotter, Jerome I.;Wilson, James G.;Bowden, Donald W.;Cupples, L. Adrienne;Haiman, Christopher A.;Loos, Ruth J. F.;North, Kari E.
Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African...
Background: Data are limited on genome-wide association studies (GWAS) for incident coronary heart disease (CHD). Moreover, it is not known whether genetic variants identified to date also associate with risk of CHD in a prospective setting. Methods:...
Escott-Price, Valentina;Bellenguez, Céline;Wang, Li-San;Choi, Seung-Hoan;Harold, Denise;Jones, Lesley;Holmans, Peter;Gerrish, Amy;Vedernikov, Alexey;Richards, Alexander;DeStefano, Anita L.;Lambert, Jean-Charles;Ibrahim-Verbaas, Carla A.;Naj, Adam C.;Sims, Rebecca;Jun, Gyungah;Bis, Joshua C.;Beecham, Gary W.;Grenier-Boley, Benjamin;Russo, Giancarlo;Thornton-Wells, Tricia A.;Denning, Nicola;Smith, Albert V.;Chouraki, Vincent;Thomas, Charlene;Ikram, M. Arfan;Zelenika, Diana;Vardarajan, Badri N.;Kamatani, Yoichiro;Lin, Chiao-Feng;Schmidt, Helena;Kunkle, Brian;Dunstan, Melanie L.;Vronskaya, Maria;Johnson, Andrew D.;Ruiz, Agustin;Bihoreau, Marie-Thérèse;Reitz, Christiane;Pasquier, Florence;Hollingworth, Paul;Hanon, Olivier;Fitzpatrick, Annette L.;Buxbaum, Joseph D.;Campion, Dominique;Crane, Paul K.;Baldwin, Clinton;Becker, Tim;Gudnason, Vilmundur;Cruchaga, Carlos;Craig, David;Amin, Najaf;Berr, Claudine;Lopez, Oscar L.;De Jager, Philip L.;Deramecourt, Vincent;Johnston, Janet A.;Evans, Denis;Lovestone, Simon;Letenneur, Luc;Hernández, Isabel;Rubinsztein, David C.;Eiriksdottir, Gudny;Sleegers, Kristel;Goate, Alison M.;Fiévet, Nathalie;Huentelman, Matthew J.;Gill, Michael;Brown, Kristelle;Kamboh, M. Ilyas;Keller, Lina;Barberger-Gateau, Pascale;McGuinness, Bernadette;Larson, Eric B.;Myers, Amanda J.;Dufouil, Carole;Todd, Stephen;Wallon, David;Love, Seth;Rogaeva, Ekaterina;Gallacher, John;George-Hyslop, Peter St;Clarimon, Jordi;Lleo, Alberto;Bayer, Anthony;Tsuang, Debby W.;Yu, Lei;Tsolaki, Magda;Bossù, Paola;Spalletta, Gianfranco;Proitsi, Petra;Collinge, John;Sorbi, Sandro;Garcia, Florentino Sanchez;Fox, Nick C.;Hardy, John;Naranjo, Maria Candida Deniz;Bosco, Paolo;Clarke, Robert;Brayne, Carol;Galimberti, Daniela;Scarpini, Elio;Bonuccelli, Ubaldo;Mancuso, Michelangelo;Siciliano, Gabriele;Moebus, Susanne;Mecocci, Patrizia;Zompo, Maria Del;Maier, Wolfgang;Hampel, Harald;Pilotto, Alberto;Frank-García, Ana;Panza, Francesco;Solfrizzi, Vincenzo;Caffarra, Paolo;Nacmias, Benedetta;Perry, William;Mayhaus, Manuel;Lannfelt, Lars;Hakonarson, Hakon;Pichler, Sabrina;Carrasquillo, Minerva M.;Ingelsson, Martin;Beekly, Duane;Alvarez, Victoria;Zou, Fanggeng;Valladares, Otto;Younkin, Steven G.;Coto, Eliecer;Hamilton-Nelson, Kara L.;Gu, Wei;Razquin, Cristina;Pastor, Pau;Mateo, Ignacio;Owen, Michael J.;Faber, Kelley M.;Jonsson, Palmi V.;Combarros, Onofre;O'Donovan, Michael C.;Cantwell, Laura B.;Soininen, Hilkka;Blacker, Deborah;Mead, Simon;Mosley, Thomas H.;Bennett, David A.;Harris, Tamara B.;Fratiglioni, Laura;Holmes, Clive;de Bruijn, Renee F. A. G.;Passmore, Peter;Montine, Thomas J.;Bettens, Karolien;Rotter, Jerome I.;Brice, Alexis;Morgan, Kevin;Foroud, Tatiana M.;Kukull, Walter A.;Hannequin, Didier;Powell, John F.;Nalls, Michael A.;Ritchie, Karen;Lunetta, Kathryn L.;Kauwe, John S. K.;Boerwinkle, Eric;Riemenschneider, Matthias;Boada, Mercè;Hiltunen, Mikko;Martin, Eden R.;Schmidt, Reinhold;Rujescu, Dan;Dartigues, Jean-François;Mayeux, Richard;Tzourio, Christophe;Hofman, Albert;Nöthen, Markus M.;Graff, Caroline;Psaty, Bruce M.;Haines, Jonathan L.;Lathrop, Mark;Pericak-Vance, Margaret A.;Launer, Lenore J.;Van Broeckhoven, Christine;Farrer, Lindsay A.;van Duijn, Cornelia M.;Ramirez, Alfredo;Seshadri, Sudha;Schellenberg, Gerard D.;Amouyel, Philippe;Williams, Julie
Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, usi...