ARTICLES
5 Article(s)
Document(s)
Title
Nejentsev, Sergey;Howson, Joanna M. M.;Walker, Neil M.;Szeszko, Jeffrey;Field, Sarah F.;Stevens, Helen E.;Reynolds, Pamela;Hardy, Matthew;King, Erna;Masters, Jennifer;Hulme, John;Maier, Lisa M.;Smyth, Deborah;Bailey, Rebecca;Cooper, Jason D.;Ribas, Gloria;Campbell, R. Duncan;Clayton, David G.;Todd, John A.;Burton, Paul R.;Clayton, David G.;Cardon, Lon R.;Craddock, Nick;Deloukas, Panos;Duncanson, Audrey;Kwiatkowski, Dominic P.;McCarthy, Mark I.;Ouwehand, Willem H.;Samani, Nilesh J.;Todd, John A.;Donnelly, Peter;Barrett, Jeffrey C.;Burton, Paul R.;Davison, Dan;Donnelly, Peter;Easton, Doug;Evans, David;Leung, Hin-Tak;Marchini, Jonathan L.;Morris, Andrew P.;Spencer, Chris C. A.;Tobin, Martin D.;Cardon, Lon R.;Clayton, David G.;Attwood, Antony P.;Boorman, James P.;Cant, Barbara;Everson, Ursula;Hussey, Judith M.;Jolley, Jennifer D.;Knight, Alexandra S.;Koch, Kerstin;Meech, Elizabeth;Nutland, Sarah;Prowse, Christopher V.;Stevens, Helen E.;Taylor, Niall C.;Walters, Graham R.;Walker, Neil M.;Watkins, Nicholas A.;Winzer, Thilo;Todd, John A.;Ouwehand, Willem H.;Jones, Richard W.;McArdle, Wendy L.;Ring, Susan M.;Strachan, David P.;Pembrey, Marcus;Breen, Gerome;St Clair, David;Caesar, Sian;Gordon-Smith, Katherine;Jones, Lisa;Fraser, Christine;Green, Elaine K.;Grozeva, Detelina;Hamshere, Marian L.;Holmans, Peter A.;Jones, Ian R.;Kirov, George;Moskvina, Valentina;Nikolov, Ivan;O’Donovan, Michael C.;Owen, Michael J.;Craddock, Nick;Collier, David A.;Elkin, Amanda;Farmer, Anne;Williamson, Richard;McGuffin, Peter;Young, Allan H.;Nicol Ferrier, I.;Ball, Stephen G.;Balmforth, Anthony J.;Barrett, Jennifer H.;Bishop, D. Timothy;Iles, Mark M.;Maqbool, Azhar;Yuldasheva, Nadira;Hall, Alistair S.;Braund, Peter S.;Burton, Paul R.;Dixon, Richard J.;Mangino, Massimo;Stevens, Suzanne;Tobin, Martin D.;Thompson, John R.;Samani, Nilesh J.;Bredin, Francesca;Tremelling, Mark;Parkes, Miles;Drummond, Hazel;Lees, Charles W.;Nimmo, Elaine R.;Satsangi, Jack;Fisher, Sheila A.;Forbes, Alastair;Lewis, Cathryn M.;Onnie, Clive M.;Prescott, Natalie J.;Sanderson, Jeremy;Mathew, Christopher G.;Barbour, Jamie;Khalid Mohiuddin, M.;Todhunter, Catherine E.;Mansfield, John C.;Ahmad, Tariq;Cummings, Fraser R.;Jewell, Derek P.;Webster, John;Brown, Morris J.;Clayton, David G.;Lathrop, G. Mark;Connell, John;Dominiczak, Anna;Samani, Nilesh J.;Braga, Carolina A.;Burke, Beverley;Dobson, Richard;Gungadoo, Johannie;Lee, Kate L.;Munroe, Patricia B.;Newhouse, Stephen J.;Onipinla, Abiodun;Wallace, Chris;Xue, Mingzhan;Caulfield, Mark;Farrall, Martin;Barton, Anne;Bruce, Ian N.;Donovan, Hannah;Eyre, Steve;Gilbert, Paul D.;Hider, Samantha L.;Hinks, Anne M.;John, Sally L.;Potter, Catherine;Silman, Alan J.;Symmons, Deborah P. M.;Thomson, Wendy;Worthington, Jane;Clayton, David G.;Dunger, David B.;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Widmer, Barry;Todd, John A.;Frayling, Timothy M.;Freathy, Rachel M.;Lango, Hana;Perry, John R. B.;Shields, Beverley M.;Weedon, Michael N.;Hattersley, Andrew T.;Hitman, Graham A.;Walker, Mark;Elliott, Kate S.;Groves, Christopher J.;Lindgren, Cecilia M.;Rayner, Nigel W.;Timpson, Nicholas J.;Zeggini, Eleftheria;McCarthy, Mark I.;Newport, Melanie;Sirugo, Giorgio;Lyons, Emily;Vannberg, Fredrik;Hill, Adrian V. S.;Bradbury, Linda A.;Farrar, Claire;Pointon, Jennifer J.;Wordsworth, Paul;Brown, Matthew A.;Franklyn, Jayne A.;Heward, Joanne M.;Simmonds, Matthew J.;Gough, Stephen C. L.;Seal, Sheila;Stratton, Michael R.;Rahman, Nazneen;Ban, Maria;Goris, An;Sawcer, Stephen J.;Compston, Alastair;Conway, David;Jallow, Muminatou;Newport, Melanie;Sirugo, Giorgio;Rockett, Kirk A.;Kwiatkowski, Dominic P.;Bryan, Claire;Bumpstead, Suzannah J.;Chaney, Amy;Downes, Kate;Ghori, Jilur;Gwilliam, Rhian;Hunt, Sarah E.;Inouye, Michael;Keniry, Andrew;King, Emma;McGinnis, Ralph;Potter, Simon;Ravindrarajah, Rathi;Whittaker, Pamela;Withers, David;Deloukas, Panos;Leung, Hin-Tak;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Todd, John A.;Easton, Doug;Clayton, David G.;Burton, Paul R.;Tobin, Martin D.;Barrett, Jeffrey C.;Evans, David;Morris, Andrew P.;Cardon, Lon R.;Cardin, Niall J.;Davison, Dan;Ferreira, Teresa;Pereira-Gale, Joanne;Hallgrimsdóttir, Ingeleif B.;Howie, Bryan N.;Marchini, Jonathan L.;Spencer, Chris C. A.;Su, Zhan;Ying Teo, Yik;Vukcevic, Damjan;Donnelly, Peter;Bentley, David;Brown, Matthew A.;Cardon, Lon R.;Caulfield, Mark;Clayton, David G.;Compston, Alistair;Craddock, Nick;Deloukas, Panos;Donnelly, Peter;Farrall, Martin;Gough, Stephen C. L.;Hall, Alistair S.;Hattersley, Andrew T.;Hill, Adrian V. S.;Kwiatkowski, Dominic P.;Mathew, Christopher G.;McCarthy, Mark I.;Ouwehand, Willem H.;Parkes, Miles;Pembrey, Marcus;Rahman, Nazneen;Samani, Nilesh J.;Stratton, Michael R.;Todd, John A.;Worthington, Jane
The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. In type 1 diabetes the major gene...
Nejentsev, Sergey;Howson, Joanna M. M.;Walker, Neil M.;Szeszko, Jeffrey;Field, Sarah F.;Stevens, Helen E.;Reynolds, Pamela;Hardy, Matthew;King, Erna;Masters, Jennifer;Hulme, John;Maier, Lisa M.;Smyth, Deborah;Bailey, Rebecca;Cooper, Jason D.;Ribas, Gloria;Campbell, R. Duncan;Clayton, David G.;Todd, John A.;Burton, Paul R.;Clayton, David G.;Cardon, Lon R.;Craddock, Nick;Deloukas, Panos;Duncanson, Audrey;Kwiatkowski, Dominic P.;McCarthy, Mark I.;Ouwehand, Willem H.;Samani, Nilesh J.;Todd, John A.;Donnelly, Peter;Barrett, Jeffrey C.;Burton, Paul R.;Davison, Dan;Donnelly, Peter;Easton, Doug;Evans, David;Leung, Hin-Tak;Marchini, Jonathan L.;Morris, Andrew P.;Spencer, Chris C. A.;Tobin, Martin D.;Cardon, Lon R.;Clayton, David G.;Attwood, Antony P.;Boorman, James P.;Cant, Barbara;Everson, Ursula;Hussey, Judith M.;Jolley, Jennifer D.;Knight, Alexandra S.;Koch, Kerstin;Meech, Elizabeth;Nutland, Sarah;Prowse, Christopher V.;Stevens, Helen E.;Taylor, Niall C.;Walters, Graham R.;Walker, Neil M.;Watkins, Nicholas A.;Winzer, Thilo;Todd, John A.;Ouwehand, Willem H.;Jones, Richard W.;McArdle, Wendy L.;Ring, Susan M.;Strachan, David P.;Pembrey, Marcus;Breen, Gerome;St Clair, David;Caesar, Sian;Gordon-Smith, Katherine;Jones, Lisa;Fraser, Christine;Green, Elaine K.;Grozeva, Detelina;Hamshere, Marian L.;Holmans, Peter A.;Jones, Ian R.;Kirov, George;Moskvina, Valentina;Nikolov, Ivan;O’Donovan, Michael C.;Owen, Michael J.;Craddock, Nick;Collier, David A.;Elkin, Amanda;Farmer, Anne;Williamson, Richard;McGuffin, Peter;Young, Allan H.;Nicol Ferrier, I.;Ball, Stephen G.;Balmforth, Anthony J.;Barrett, Jennifer H.;Bishop, D. Timothy;Iles, Mark M.;Maqbool, Azhar;Yuldasheva, Nadira;Hall, Alistair S.;Braund, Peter S.;Burton, Paul R.;Dixon, Richard J.;Mangino, Massimo;Stevens, Suzanne;Tobin, Martin D.;Thompson, John R.;Samani, Nilesh J.;Bredin, Francesca;Tremelling, Mark;Parkes, Miles;Drummond, Hazel;Lees, Charles W.;Nimmo, Elaine R.;Satsangi, Jack;Fisher, Sheila A.;Forbes, Alastair;Lewis, Cathryn M.;Onnie, Clive M.;Prescott, Natalie J.;Sanderson, Jeremy;Mathew, Christopher G.;Barbour, Jamie;Khalid Mohiuddin, M.;Todhunter, Catherine E.;Mansfield, John C.;Ahmad, Tariq;Cummings, Fraser R.;Jewell, Derek P.;Webster, John;Brown, Morris J.;Clayton, David G.;Lathrop, G. Mark;Connell, John;Dominiczak, Anna;Samani, Nilesh J.;Braga, Carolina A.;Burke, Beverley;Dobson, Richard;Gungadoo, Johannie;Lee, Kate L.;Munroe, Patricia B.;Newhouse, Stephen J.;Onipinla, Abiodun;Wallace, Chris;Xue, Mingzhan;Caulfield, Mark;Farrall, Martin;Barton, Anne;Bruce, Ian N.;Donovan, Hannah;Eyre, Steve;Gilbert, Paul D.;Hider, Samantha L.;Hinks, Anne M.;John, Sally L.;Potter, Catherine;Silman, Alan J.;Symmons, Deborah P. M.;Thomson, Wendy;Worthington, Jane;Clayton, David G.;Dunger, David B.;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Widmer, Barry;Todd, John A.;Frayling, Timothy M.;Freathy, Rachel M.;Lango, Hana;Perry, John R. B.;Shields, Beverley M.;Weedon, Michael N.;Hattersley, Andrew T.;Hitman, Graham A.;Walker, Mark;Elliott, Kate S.;Groves, Christopher J.;Lindgren, Cecilia M.;Rayner, Nigel W.;Timpson, Nicholas J.;Zeggini, Eleftheria;McCarthy, Mark I.;Newport, Melanie;Sirugo, Giorgio;Lyons, Emily;Vannberg, Fredrik;Hill, Adrian V. S.;Bradbury, Linda A.;Farrar, Claire;Pointon, Jennifer J.;Wordsworth, Paul;Brown, Matthew A.;Franklyn, Jayne A.;Heward, Joanne M.;Simmonds, Matthew J.;Gough, Stephen C. L.;Seal, Sheila;Stratton, Michael R.;Rahman, Nazneen;Ban, Maria;Goris, An;Sawcer, Stephen J.;Compston, Alastair;Conway, David;Jallow, Muminatou;Newport, Melanie;Sirugo, Giorgio;Rockett, Kirk A.;Kwiatkowski, Dominic P.;Bryan, Claire;Bumpstead, Suzannah J.;Chaney, Amy;Downes, Kate;Ghori, Jilur;Gwilliam, Rhian;Hunt, Sarah E.;Inouye, Michael;Keniry, Andrew;King, Emma;McGinnis, Ralph;Potter, Simon;Ravindrarajah, Rathi;Whittaker, Pamela;Withers, David;Deloukas, Panos;Leung, Hin-Tak;Nutland, Sarah;Stevens, Helen E.;Walker, Neil M.;Todd, John A.;Easton, Doug;Clayton, David G.;Burton, Paul R.;Tobin, Martin D.;Barrett, Jeffrey C.;Evans, David;Morris, Andrew P.;Cardon, Lon R.;Cardin, Niall J.;Davison, Dan;Ferreira, Teresa;Pereira-Gale, Joanne;Hallgrimsdóttir, Ingeleif B.;Howie, Bryan N.;Marchini, Jonathan L.;Spencer, Chris C. A.;Su, Zhan;Ying Teo, Yik;Vukcevic, Damjan;Donnelly, Peter;Bentley, David;Brown, Matthew A.;Cardon, Lon R.;Caulfield, Mark;Clayton, David G.;Compston, Alistair;Craddock, Nick;Deloukas, Panos;Donnelly, Peter;Farrall, Martin;Gough, Stephen C. L.;Hall, Alistair S.;Hattersley, Andrew T.;Hill, Adrian V. S.;Kwiatkowski, Dominic P.;Mathew, Christopher G.;McCarthy, Mark I.;Ouwehand, Willem H.;Parkes, Miles;Pembrey, Marcus;Rahman, Nazneen;Samani, Nilesh J.;Stratton, Michael R.;Todd, John A.;Worthington, Jane
The major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more common diseases than any other region of the human genome, including almost all disorders classified as autoimmune. In type 1 diabetes the major gene...
BACKGROUND Understanding of the genetic basis of type 2 diabetes (T2D) has progressed rapidly, but the interactions between common genetic variants and lifestyle risk factors have not been systematically investigated in studies with adequate statisti...
Genome-wide association studies have identified hundreds of loci for type 2 diabetes, coronary artery disease and myocardial infarction, as well as for related traits such as body mass index, glucose and insulin levels, lipid levels, and blood pressu...