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Flannick, Jason;Fuchsberger, Christian;Mahajan, Anubha;Teslovich, Tanya M.;Agarwala, Vineeta;Gaulton, Kyle J.;Caulkins, Lizz;Koesterer, Ryan;Ma, Clement;Moutsianas, Loukas;McCarthy, Davis J.;Rivas, Manuel A.;Perry, John R.B.;Sim, Xueling;Blackwell, Thomas W.;Robertson, Neil R.;Rayner, N. William;Cingolani, Pablo;Locke, Adam E.;Tajes, Juan Fernandez;Highland, Heather M.;Dupuis, Josée;Chines, Peter S.;Lindgren, Cecilia M.;Hartl, Christopher;Jackson, Anne U.;Chen, Han;Huyghe, Jeroen R.;Van De Bunt, Martijn;Pearson, Richard D.;Kumar, Ashish;Müller-Nurasyid, Martina;Grarup, Niels;Stringham, Heather M.;Gamazon, Eric R.;Lee, Jaehoon;Chen, Yuhui;Scott, Robert A.;Below, Jennifer E.;Chen, Peng;Huang, Jinyan;Go, Min Jin;Stitzel, Michael L.;Pasko, Dorota;Parker, Stephen C.J.;Varga, Tibor V.;Green, Todd;Beer, Nicola L.;Day-Williams, Aaron G.;Ferreira, Teresa;Fingerlin, Tasha;Horikoshi, Momoko;Hu, Cheng;Huh, Iksoo;Ikram, Mohammad Kamran;Kim, Bong-Jo;Kim, Yongkang;Kim, Young Jin;Kwon, Min-Seok;Lee, Juyoung;Lee, Selyeong;Lin, Keng-Han;Maxwell, Taylor J.;Nagai, Yoshihiko;Wang, Xu;Welch, Ryan P.;Yoon, Joon;Zhang, Weihua;Barzilai, Nir;Voight, Benjamin F.;Han, Bok-Ghee;Jenkinson, Christopher P.;Kuulasmaa, Teemu;Kuusisto, Johanna;Manning, Alisa;Ng, Maggie C.Y.;Palmer, Nicholette D.;Balkau, Beverley;Stančáková, Alena;Abboud, Hanna E.;Boeing, Heiner;Giedraitis, Vilmantas;Prabhakaran, Dorairaj;Gottesman, Omri;Scott, James;Carey, Jason;Kwan, Phoenix;Grant, George;Smith, Joshua D.;Neale, Benjamin M.;Purcell, Shaun;Butterworth, Adam S.;Howson, Joanna M.M.;Lee, Heung Man;Lu, Yingchang;Kwak, Soo-Heon;Zhao, Wei;Danesh, John;Lam, Vincent K.L.;Park, Kyong Soo;Saleheen, Danish;So, Wing Yee;Tam, Claudia H.T.;Afzal, Uzma;Aguilar, David;Arya, Rector;Aung, Tin;Chan, Edmund;Navarro, Carmen;Cheng, Ching-Yu;Palli, Domenico;Correa, Adolfo;Curran, Joanne E.;Rybin, Dennis;Farook, Vidya S.;Fowler, Sharon P.;Freedman, Barry I.;Griswold, Michael;Hale, Daniel Esten;Hicks, Pamela J.;Khor, Chiea-Chuen;Kumar, Satish;Lehne, Benjamin;Thuillier, Dorothée;Lim, Wei Yen;Liu, Jianjun;Loh, Marie;Musani, Solomon K.;Puppala, Sobha;Scott, William R.;Yengo, Loïc;Tan, Sian-Tsung;Taylor, Herman A.;Thameem, Farook;Wilson, Gregory;Wong, Tien Yin;Njølstad, Pål Rasmus;Levy, Jonathan C.;Mangino, Massimo;Bonnycastle, Lori L.;Schwarzmayr, Thomas;Fadista, João;Surdulescu, Gabriela L.;Herder, Christian;Groves, Christopher J.;Wieland, Thomas;Bork-Jensen, Jette;Brandslund, Ivan;Christensen, Cramer;Koistinen, Heikki A.;Doney, Alex S.F.;Kinnunen, Leena;Esko, Tõnu;Farmer, Andrew J.;Hakaste, Liisa;Hodgkiss, Dylan;Kravic, Jasmina;Lyssenko, Valeriya;Hollensted, Mette;Jørgensen, Marit E.;Jørgensen, Torben;Ladenvall, Claes;Justesen, Johanne Marie;Käräjämäki, Annemari;Kriebel, Jennifer;Rathmann, Wolfgang;Lannfelt, Lars;Lauritzen, Torsten;Narisu, Narisu;Linneberg, Allan;Melander, Olle;Milani, Lili;Neville, Matt;Orho-Melander, Marju;Qi, Lu;Qi, Qibin;Roden, Michael;Rolandsson, Olov;Swift, Amy;Rosengren, Anders H.;Stirrups, Kathleen;Wood, Andrew R.;Mihailov, Evelin;Blancher, Christine;Carneiro, Mauricio O.;Maguire, Jared;Poplin, Ryan;Shakir, Khalid;Fennell, Timothy;DePristo, Mark;De Angelis, Martin Hrabé;Deloukas, Panos;Gjesing, Anette P.;Jun, Goo;Nilsson, Peter M.;Murphy, Jacquelyn;Onofrio, Robert;Thorand, Barbara;Hansen, Torben;Meisinger, Christa;Hu, Frank B.;Isomaa, Bo;Karpe, Fredrik;Liang, Liming;Peters, Annette;Huth, Cornelia;O'Rahilly, Stephen P.;Palmer, Colin N.A.;Pedersen, Oluf;Rauramaa, Rainer;Tuomilehto, Jaakko;Salomaa, Veikko;Watanabe, Richard M.;Syvänen, Ann-Christine;Bergman, Richard N.;Bharadwaj, Dwaipayan;Bottinger, Erwin P.;Cho, Yoon Shin;Chandak, Giriraj R.;Chan, Juliana C.N.;Chia, Kee Seng;Daly, Mark J.;Ebrahim, Shah B.;Langenberg, Claudia;Elliott, Paul;Jablonski, Kathleen A.;Lehman, Donna M.;Jia, Weiping;Ma, Ronald C.W.;Pollin, Toni I.;Sandhu, Manjinder;Tandon, Nikhil;Froguel, Philippe;Barroso, Inês;Teo, Yik Ying;Zeggini, Eleftheria;Loos, Ruth J.F.;Small, Kerrin S.;Ried, Janina S.;DeFronzo, Ralph A.;Grallert, Harald;Glaser, Benjamin;Metspalu, Andres;Wareham, Nicholas J.;Walker, Mark;Banks, Eric;Gieger, Christian;Ingelsson, Erik;Im, Hae Kyung;Illig, Thomas;Franks, Paul W.;Buck, Gemma;Trakalo, Joseph;Buck, David;Prokopenko, Inga;Mägi, Reedik;Lind, Lars;Farjoun, Yossi;Owen, Katharine R.;Gloyn, Anna L.;Strauch, Konstantin;Tuomi, Tiinamaija;Kooner, Jaspal Singh;Lee, Jong-Young;Park, Taesung;Donnelly, Peter;Morris, Andrew D.;Hattersley, Andrew T.;Bowden, Donald W.;Collins, Francis S.;Atzmon, Gil;Chambers, John C.;Spector, Timothy D.;Laakso, Markku;Strom, Tim M.;Bell, Graeme I.;Blangero, John;Duggirala, Ravindranath;Tai, Eshyong;McVean, Gilean;Hanis, Craig L.;Wilson, James G.;Seielstad, Mark;Frayling, Timothy M.;Meigs, James B.;Cox, Nancy J.;Sladek, Rob;Lander, Eric S.;Gabriel, Stacey;Mohlke, Karen L.;Meitinger, Thomas;Groop, Leif;Abecasis, Goncalo;Scott, Laura J.;Morris, Andrew P.;Kang, Hyun Min;Altshuler, David;Burtt, Noël P.;Florez, Jose C.;Boehnke, Michael;McCarthy, Mark I.
To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 12,940 individuals of multiple anc...
Flannick, Jason;Fuchsberger, Christian;Mahajan, Anubha;Teslovich, Tanya M.;Agarwala, Vineeta;Gaulton, Kyle J.;Caulkins, Lizz;Koesterer, Ryan;Ma, Clement;Moutsianas, Loukas;McCarthy, Davis J.;Rivas, Manuel A.;Perry, John R.B.;Sim, Xueling;Blackwell, Thomas W.;Robertson, Neil R.;Rayner, N. William;Cingolani, Pablo;Locke, Adam E.;Tajes, Juan Fernandez;Highland, Heather M.;Dupuis, Josée;Chines, Peter S.;Lindgren, Cecilia M.;Hartl, Christopher;Jackson, Anne U.;Chen, Han;Huyghe, Jeroen R.;Van De Bunt, Martijn;Pearson, Richard D.;Kumar, Ashish;Müller-Nurasyid, Martina;Grarup, Niels;Stringham, Heather M.;Gamazon, Eric R.;Lee, Jaehoon;Chen, Yuhui;Scott, Robert A.;Below, Jennifer E.;Chen, Peng;Huang, Jinyan;Go, Min Jin;Stitzel, Michael L.;Pasko, Dorota;Parker, Stephen C.J.;Varga, Tibor V.;Green, Todd;Beer, Nicola L.;Day-Williams, Aaron G.;Ferreira, Teresa;Fingerlin, Tasha;Horikoshi, Momoko;Hu, Cheng;Huh, Iksoo;Ikram, Mohammad Kamran;Kim, Bong-Jo;Kim, Yongkang;Kim, Young Jin;Kwon, Min-Seok;Lee, Juyoung;Lee, Selyeong;Lin, Keng-Han;Maxwell, Taylor J.;Nagai, Yoshihiko;Wang, Xu;Welch, Ryan P.;Yoon, Joon;Zhang, Weihua;Barzilai, Nir;Voight, Benjamin F.;Han, Bok-Ghee;Jenkinson, Christopher P.;Kuulasmaa, Teemu;Kuusisto, Johanna;Manning, Alisa;Ng, Maggie C.Y.;Palmer, Nicholette D.;Balkau, Beverley;Stančáková, Alena;Abboud, Hanna E.;Boeing, Heiner;Giedraitis, Vilmantas;Prabhakaran, Dorairaj;Gottesman, Omri;Scott, James;Carey, Jason;Kwan, Phoenix;Grant, George;Smith, Joshua D.;Neale, Benjamin M.;Purcell, Shaun;Butterworth, Adam S.;Howson, Joanna M.M.;Lee, Heung Man;Lu, Yingchang;Kwak, Soo-Heon;Zhao, Wei;Danesh, John;Lam, Vincent K.L.;Park, Kyong Soo;Saleheen, Danish;So, Wing Yee;Tam, Claudia H.T.;Afzal, Uzma;Aguilar, David;Arya, Rector;Aung, Tin;Chan, Edmund;Navarro, Carmen;Cheng, Ching-Yu;Palli, Domenico;Correa, Adolfo;Curran, Joanne E.;Rybin, Dennis;Farook, Vidya S.;Fowler, Sharon P.;Freedman, Barry I.;Griswold, Michael;Hale, Daniel Esten;Hicks, Pamela J.;Khor, Chiea-Chuen;Kumar, Satish;Lehne, Benjamin;Thuillier, Dorothée;Lim, Wei Yen;Liu, Jianjun;Loh, Marie;Musani, Solomon K.;Puppala, Sobha;Scott, William R.;Yengo, Loïc;Tan, Sian-Tsung;Taylor, Herman A.;Thameem, Farook;Wilson, Gregory;Wong, Tien Yin;Njølstad, Pål Rasmus;Levy, Jonathan C.;Mangino, Massimo;Bonnycastle, Lori L.;Schwarzmayr, Thomas;Fadista, João;Surdulescu, Gabriela L.;Herder, Christian;Groves, Christopher J.;Wieland, Thomas;Bork-Jensen, Jette;Brandslund, Ivan;Christensen, Cramer;Koistinen, Heikki A.;Doney, Alex S.F.;Kinnunen, Leena;Esko, Tõnu;Farmer, Andrew J.;Hakaste, Liisa;Hodgkiss, Dylan;Kravic, Jasmina;Lyssenko, Valeriya;Hollensted, Mette;Jørgensen, Marit E.;Jørgensen, Torben;Ladenvall, Claes;Justesen, Johanne Marie;Käräjämäki, Annemari;Kriebel, Jennifer;Rathmann, Wolfgang;Lannfelt, Lars;Lauritzen, Torsten;Narisu, Narisu;Linneberg, Allan;Melander, Olle;Milani, Lili;Neville, Matt;Orho-Melander, Marju;Qi, Lu;Qi, Qibin;Roden, Michael;Rolandsson, Olov;Swift, Amy;Rosengren, Anders H.;Stirrups, Kathleen;Wood, Andrew R.;Mihailov, Evelin;Blancher, Christine;Carneiro, Mauricio O.;Maguire, Jared;Poplin, Ryan;Shakir, Khalid;Fennell, Timothy;DePristo, Mark;De Angelis, Martin Hrabé;Deloukas, Panos;Gjesing, Anette P.;Jun, Goo;Nilsson, Peter M.;Murphy, Jacquelyn;Onofrio, Robert;Thorand, Barbara;Hansen, Torben;Meisinger, Christa;Hu, Frank B.;Isomaa, Bo;Karpe, Fredrik;Liang, Liming;Peters, Annette;Huth, Cornelia;O'Rahilly, Stephen P.;Palmer, Colin N.A.;Pedersen, Oluf;Rauramaa, Rainer;Tuomilehto, Jaakko;Salomaa, Veikko;Watanabe, Richard M.;Syvänen, Ann-Christine;Bergman, Richard N.;Bharadwaj, Dwaipayan;Bottinger, Erwin P.;Cho, Yoon Shin;Chandak, Giriraj R.;Chan, Juliana C.N.;Chia, Kee Seng;Daly, Mark J.;Ebrahim, Shah B.;Langenberg, Claudia;Elliott, Paul;Jablonski, Kathleen A.;Lehman, Donna M.;Jia, Weiping;Ma, Ronald C.W.;Pollin, Toni I.;Sandhu, Manjinder;Tandon, Nikhil;Froguel, Philippe;Barroso, Inês;Teo, Yik Ying;Zeggini, Eleftheria;Loos, Ruth J.F.;Small, Kerrin S.;Ried, Janina S.;DeFronzo, Ralph A.;Grallert, Harald;Glaser, Benjamin;Metspalu, Andres;Wareham, Nicholas J.;Walker, Mark;Banks, Eric;Gieger, Christian;Ingelsson, Erik;Im, Hae Kyung;Illig, Thomas;Franks, Paul W.;Buck, Gemma;Trakalo, Joseph;Buck, David;Prokopenko, Inga;Mägi, Reedik;Lind, Lars;Farjoun, Yossi;Owen, Katharine R.;Gloyn, Anna L.;Strauch, Konstantin;Tuomi, Tiinamaija;Kooner, Jaspal Singh;Lee, Jong-Young;Park, Taesung;Donnelly, Peter;Morris, Andrew D.;Hattersley, Andrew T.;Bowden, Donald W.;Collins, Francis S.;Atzmon, Gil;Chambers, John C.;Spector, Timothy D.;Laakso, Markku;Strom, Tim M.;Bell, Graeme I.;Blangero, John;Duggirala, Ravindranath;Tai, Eshyong;McVean, Gilean;Hanis, Craig L.;Wilson, James G.;Seielstad, Mark;Frayling, Timothy M.;Meigs, James B.;Cox, Nancy J.;Sladek, Rob;Lander, Eric S.;Gabriel, Stacey;Mohlke, Karen L.;Meitinger, Thomas;Groop, Leif;Abecasis, Goncalo;Scott, Laura J.;Morris, Andrew P.;Kang, Hyun Min;Altshuler, David;Burtt, Noël P.;Florez, Jose C.;Boehnke, Michael;McCarthy, Mark I.
To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 12,940 individuals of multiple anc...
Flannick, Jason;Fuchsberger, Christian;Mahajan, Anubha;Teslovich, Tanya M.;Agarwala, Vineeta;Gaulton, Kyle J.;Caulkins, Lizz;Koesterer, Ryan;Ma, Clement;Moutsianas, Loukas;McCarthy, Davis J.;Rivas, Manuel A.;Perry, John R.B.;Sim, Xueling;Blackwell, Thomas W.;Robertson, Neil R.;Rayner, N. William;Cingolani, Pablo;Locke, Adam E.;Tajes, Juan Fernandez;Highland, Heather M.;Dupuis, Josée;Chines, Peter S.;Lindgren, Cecilia M.;Hartl, Christopher;Jackson, Anne U.;Chen, Han;Huyghe, Jeroen R.;Van De Bunt, Martijn;Pearson, Richard D.;Kumar, Ashish;Müller-Nurasyid, Martina;Grarup, Niels;Stringham, Heather M.;Gamazon, Eric R.;Lee, Jaehoon;Chen, Yuhui;Scott, Robert A.;Below, Jennifer E.;Chen, Peng;Huang, Jinyan;Go, Min Jin;Stitzel, Michael L.;Pasko, Dorota;Parker, Stephen C.J.;Varga, Tibor V.;Green, Todd;Beer, Nicola L.;Day-Williams, Aaron G.;Ferreira, Teresa;Fingerlin, Tasha;Horikoshi, Momoko;Hu, Cheng;Huh, Iksoo;Ikram, Mohammad Kamran;Kim, Bong-Jo;Kim, Yongkang;Kim, Young Jin;Kwon, Min-Seok;Lee, Juyoung;Lee, Selyeong;Lin, Keng-Han;Maxwell, Taylor J.;Nagai, Yoshihiko;Wang, Xu;Welch, Ryan P.;Yoon, Joon;Zhang, Weihua;Barzilai, Nir;Voight, Benjamin F.;Han, Bok-Ghee;Jenkinson, Christopher P.;Kuulasmaa, Teemu;Kuusisto, Johanna;Manning, Alisa;Ng, Maggie C.Y.;Palmer, Nicholette D.;Balkau, Beverley;Stančáková, Alena;Abboud, Hanna E.;Boeing, Heiner;Giedraitis, Vilmantas;Prabhakaran, Dorairaj;Gottesman, Omri;Scott, James;Carey, Jason;Kwan, Phoenix;Grant, George;Smith, Joshua D.;Neale, Benjamin M.;Purcell, Shaun;Butterworth, Adam S.;Howson, Joanna M.M.;Lee, Heung Man;Lu, Yingchang;Kwak, Soo-Heon;Zhao, Wei;Danesh, John;Lam, Vincent K.L.;Park, Kyong Soo;Saleheen, Danish;So, Wing Yee;Tam, Claudia H.T.;Afzal, Uzma;Aguilar, David;Arya, Rector;Aung, Tin;Chan, Edmund;Navarro, Carmen;Cheng, Ching-Yu;Palli, Domenico;Correa, Adolfo;Curran, Joanne E.;Rybin, Dennis;Farook, Vidya S.;Fowler, Sharon P.;Freedman, Barry I.;Griswold, Michael;Hale, Daniel Esten;Hicks, Pamela J.;Khor, Chiea-Chuen;Kumar, Satish;Lehne, Benjamin;Thuillier, Dorothée;Lim, Wei Yen;Liu, Jianjun;Loh, Marie;Musani, Solomon K.;Puppala, Sobha;Scott, William R.;Yengo, Loïc;Tan, Sian-Tsung;Taylor, Herman A.;Thameem, Farook;Wilson, Gregory;Wong, Tien Yin;Njølstad, Pål Rasmus;Levy, Jonathan C.;Mangino, Massimo;Bonnycastle, Lori L.;Schwarzmayr, Thomas;Fadista, João;Surdulescu, Gabriela L.;Herder, Christian;Groves, Christopher J.;Wieland, Thomas;Bork-Jensen, Jette;Brandslund, Ivan;Christensen, Cramer;Koistinen, Heikki A.;Doney, Alex S.F.;Kinnunen, Leena;Esko, Tõnu;Farmer, Andrew J.;Hakaste, Liisa;Hodgkiss, Dylan;Kravic, Jasmina;Lyssenko, Valeriya;Hollensted, Mette;Jørgensen, Marit E.;Jørgensen, Torben;Ladenvall, Claes;Justesen, Johanne Marie;Käräjämäki, Annemari;Kriebel, Jennifer;Rathmann, Wolfgang;Lannfelt, Lars;Lauritzen, Torsten;Narisu, Narisu;Linneberg, Allan;Melander, Olle;Milani, Lili;Neville, Matt;Orho-Melander, Marju;Qi, Lu;Qi, Qibin;Roden, Michael;Rolandsson, Olov;Swift, Amy;Rosengren, Anders H.;Stirrups, Kathleen;Wood, Andrew R.;Mihailov, Evelin;Blancher, Christine;Carneiro, Mauricio O.;Maguire, Jared;Poplin, Ryan;Shakir, Khalid;Fennell, Timothy;DePristo, Mark;De Angelis, Martin Hrabé;Deloukas, Panos;Gjesing, Anette P.;Jun, Goo;Nilsson, Peter M.;Murphy, Jacquelyn;Onofrio, Robert;Thorand, Barbara;Hansen, Torben;Meisinger, Christa;Hu, Frank B.;Isomaa, Bo;Karpe, Fredrik;Liang, Liming;Peters, Annette;Huth, Cornelia;O'Rahilly, Stephen P.;Palmer, Colin N.A.;Pedersen, Oluf;Rauramaa, Rainer;Tuomilehto, Jaakko;Salomaa, Veikko;Watanabe, Richard M.;Syvänen, Ann-Christine;Bergman, Richard N.;Bharadwaj, Dwaipayan;Bottinger, Erwin P.;Cho, Yoon Shin;Chandak, Giriraj R.;Chan, Juliana C.N.;Chia, Kee Seng;Daly, Mark J.;Ebrahim, Shah B.;Langenberg, Claudia;Elliott, Paul;Jablonski, Kathleen A.;Lehman, Donna M.;Jia, Weiping;Ma, Ronald C.W.;Pollin, Toni I.;Sandhu, Manjinder;Tandon, Nikhil;Froguel, Philippe;Barroso, Inês;Teo, Yik Ying;Zeggini, Eleftheria;Loos, Ruth J.F.;Small, Kerrin S.;Ried, Janina S.;DeFronzo, Ralph A.;Grallert, Harald;Glaser, Benjamin;Metspalu, Andres;Wareham, Nicholas J.;Walker, Mark;Banks, Eric;Gieger, Christian;Ingelsson, Erik;Im, Hae Kyung;Illig, Thomas;Franks, Paul W.;Buck, Gemma;Trakalo, Joseph;Buck, David;Prokopenko, Inga;Mägi, Reedik;Lind, Lars;Farjoun, Yossi;Owen, Katharine R.;Gloyn, Anna L.;Strauch, Konstantin;Tuomi, Tiinamaija;Kooner, Jaspal Singh;Lee, Jong-Young;Park, Taesung;Donnelly, Peter;Morris, Andrew D.;Hattersley, Andrew T.;Bowden, Donald W.;Collins, Francis S.;Atzmon, Gil;Chambers, John C.;Spector, Timothy D.;Laakso, Markku;Strom, Tim M.;Bell, Graeme I.;Blangero, John;Duggirala, Ravindranath;Tai, Eshyong;McVean, Gilean;Hanis, Craig L.;Wilson, James G.;Seielstad, Mark;Frayling, Timothy M.;Meigs, James B.;Cox, Nancy J.;Sladek, Rob;Lander, Eric S.;Gabriel, Stacey;Mohlke, Karen L.;Meitinger, Thomas;Groop, Leif;Abecasis, Goncalo;Scott, Laura J.;Morris, Andrew P.;Kang, Hyun Min;Altshuler, David;Burtt, Noël P.;Florez, Jose C.;Boehnke, Michael;McCarthy, Mark I.
To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 12,940 individuals of multiple anc...
Wheeler, Eleanor;Leong, Aaron;Liu, Ching-Ti;Hivert, Marie-France;Strawbridge, Rona J.;Podmore, Clara;Li, Man;Yao, Jie;Sim, Xueling;Hong, Jaeyoung;Chu, Audrey Y.;Zhang, Weihua;Wang, Xu;Chen, Peng;Maruthur, Nisa M.;Porneala, Bianca C.;Sharp, Stephen J.;Jia, Yucheng;Kabagambe, Edmond K.;Chang, Li-Ching;Chen, Wei-Min;Elks, Cathy E.;Evans, Daniel S.;Fan, Qiao;Giulianini, Franco;Go, Min Jin;Hottenga, Jouke-Jan;Hu, Yao;Jackson, Anne U.;Kanoni, Stavroula;Kim, Young Jin;Kleber, Marcus E.;Ladenvall, Claes;Lecoeur, Cecile;Lim, Sing-Hui;Lu, Yingchang;Mahajan, Anubha;Marzi, Carola;Nalls, Mike A.;Navarro, Pau;Nolte, Ilja M.;Rose, Lynda M.;Rybin, Denis V.;Sanna, Serena;Shi, Yuan;Stram, Daniel O.;Takeuchi, Fumihiko;Tan, Shu Pei;van der Most, Peter J.;Van Vliet-Ostaptchouk, Jana V.;Wong, Andrew;Yengo, Loic;Zhao, Wanting;Goel, Anuj;Martinez Larrad, Maria Teresa;Radke, Dörte;Salo, Perttu;Tanaka, Toshiko;van Iperen, Erik P. A.;Abecasis, Goncalo;Afaq, Saima;Alizadeh, Behrooz Z.;Bertoni, Alain G.;Bonnefond, Amelie;Böttcher, Yvonne;Bottinger, Erwin P.;Campbell, Harry;Carlson, Olga D.;Chen, Chien-Hsiun;Cho, Yoon Shin;Garvey, W. Timothy;Gieger, Christian;Goodarzi, Mark O.;Grallert, Harald;Hamsten, Anders;Hartman, Catharina A.;Herder, Christian;Hsiung, Chao Agnes;Huang, Jie;Igase, Michiya;Isono, Masato;Katsuya, Tomohiro;Khor, Chiea-Chuen;Kiess, Wieland;Kohara, Katsuhiko;Kovacs, Peter;Lee, Juyoung;Lee, Wen-Jane;Lehne, Benjamin;Li, Huaixing;Liu, Jianjun;Lobbens, Stephane;Luan, Jian'an;Lyssenko, Valeriya;Meitinger, Thomas;Miki, Tetsuro;Miljkovic, Iva;Moon, Sanghoon;Mulas, Antonella;Müller, Gabriele;Müller-Nurasyid, Martina;Nagaraja, Ramaiah;Nauck, Matthias;Pankow, James S.;Polasek, Ozren;Prokopenko, Inga;Ramos, Paula S.;Rasmussen-Torvik, Laura;Rathmann, Wolfgang;Rich, Stephen S.;Robertson, Neil R.;Roden, Michael;Roussel, Ronan;Rudan, Igor;Scott, Robert A.;Scott, William R.;Sennblad, Bengt;Siscovick, David S.;Strauch, Konstantin;Sun, Liang;Swertz, Morris;Tajuddin, Salman M.;Taylor, Kent D.;Teo, Yik-Ying;Tham, Yih Chung;Tönjes, Anke;Wareham, Nicholas J.;Willemsen, Gonneke;Wilsgaard, Tom;Hingorani, Aroon D.;Egan, Josephine;Ferrucci, Luigi;Hovingh, G. Kees;Jula, Antti;Kivimaki, Mika;Kumari, Meena;Njølstad, Inger;Palmer, Colin N. A.;Serrano Ríos, Manuel;Stumvoll, Michael;Watkins, Hugh;Aung, Tin;Blüher, Matthias;Boehnke, Michael;Boomsma, Dorret I.;Bornstein, Stefan R.;Chambers, John C.;Chasman, Daniel I.;Chen, Yii-Der Ida;Chen, Yduan-Tsong;Cheng, Ching-Yu;Cucca, Francesco;de Geus, Eco J. C.;Deloukas, Panos;Evans, Michele K.;Fornage, Myriam;Friedlander, Yechiel;Froguel, Philippe;Groop, Leif;Gross, Myron D.;Harris, Tamara B.;Hayward, Caroline;Heng, Chew-Kiat;Ingelsson, Erik;Kato, Norihiro;Kim, Bong-Jo;Koh, Woon-Puay;Kooner, Jaspal S.;Körner, Antje;Kuh, Diana;Kuusisto, Johanna;Laakso, Markku;Lin, Xu;Liu, Yongmei;Loos, Ruth J. F.;Magnusson, Patrik K. E.;März, Winfried;McCarthy, Mark I.;Oldehinkel, Albertine J.;Ong, Ken K.;Pedersen, Nancy L.;Pereira, Mark A.;Peters, Annette;Ridker, Paul M.;Sabanayagam, Charumathi;Sale, Michele;Saleheen, Danish;Saltevo, Juha;Schwarz, Peter EH.;Sheu, Wayne H. H.;Snieder, Harold;Spector, Timothy D.;Tabara, Yasuharu;Tuomilehto, Jaakko;van Dam, Rob M.;Wilson, James G.;Wilson, James F.;Wolffenbuttel, Bruce H. R.;Wong, Tien Yin;Wu, Jer-Yuarn;Yuan, Jian-Min;Zonderman, Alan B.;Soranzo, Nicole;Guo, Xiuqing;Roberts, David J.;Florez, Jose C.;Sladek, Robert;Dupuis, Josée;Morris, Andrew P.;Tai, E-Shyong;Selvin, Elizabeth;Rotter, Jerome I.;Langenberg, Claudia;Barroso, Inês;Meigs, James B.
Background: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These varia...
Graff, Mariaelisa;Scott, Robert A.;Justice, Anne E.;Young, Kristin L.;Feitosa, Mary F.;Barata, Llilda;Winkler, Thomas W.;Chu, Audrey Y.;Mahajan, Anubha;Hadley, David;Xue, Luting;Workalemahu, Tsegaselassie;Heard-Costa, Nancy L.;den Hoed, Marcel;Ahluwalia, Tarunveer S.;Qi, Qibin;Ngwa, Julius S.;Renström, Frida;Quaye, Lydia;Eicher, John D.;Hayes, James E.;Cornelis, Marilyn;Kutalik, Zoltan;Lim, Elise;Luan, Jian’an;Huffman, Jennifer E.;Zhang, Weihua;Zhao, Wei;Griffin, Paula J.;Haller, Toomas;Ahmad, Shafqat;Marques-Vidal, Pedro M.;Bien, Stephanie;Yengo, Loic;Teumer, Alexander;Smith, Albert Vernon;Kumari, Meena;Harder, Marie Neergaard;Justesen, Johanne Marie;Kleber, Marcus E.;Hollensted, Mette;Lohman, Kurt;Rivera, Natalia V.;Whitfield, John B.;Zhao, Jing Hua;Stringham, Heather M.;Lyytikäinen, Leo-Pekka;Huppertz, Charlotte;Willemsen, Gonneke;Peyrot, Wouter J.;Wu, Ying;Kristiansson, Kati;Demirkan, Ayse;Fornage, Myriam;Hassinen, Maija;Bielak, Lawrence F.;Cadby, Gemma;Tanaka, Toshiko;Mägi, Reedik;van der Most, Peter J.;Jackson, Anne U.;Bragg-Gresham, Jennifer L.;Vitart, Veronique;Marten, Jonathan;Navarro, Pau;Bellis, Claire;Pasko, Dorota;Johansson, Åsa;Snitker, Søren;Cheng, Yu-Ching;Eriksson, Joel;Lim, Unhee;Aadahl, Mette;Adair, Linda S.;Amin, Najaf;Balkau, Beverley;Auvinen, Juha;Beilby, John;Bergman, Richard N.;Bergmann, Sven;Bertoni, Alain G.;Blangero, John;Bonnefond, Amélie;Bonnycastle, Lori L.;Borja, Judith B.;Brage, Søren;Busonero, Fabio;Buyske, Steve;Campbell, Harry;Chines, Peter S.;Collins, Francis S.;Corre, Tanguy;Smith, George Davey;Delgado, Graciela E.;Dueker, Nicole;Dörr, Marcus;Ebeling, Tapani;Eiriksdottir, Gudny;Esko, Tõnu;Faul, Jessica D.;Fu, Mao;Færch, Kristine;Gieger, Christian;Gläser, Sven;Gong, Jian;Gordon-Larsen, Penny;Grallert, Harald;Grammer, Tanja B.;Grarup, Niels;van Grootheest, Gerard;Harald, Kennet;Hastie, Nicholas D.;Havulinna, Aki S.;Hernandez, Dena;Hindorff, Lucia;Hocking, Lynne J.;Holmens, Oddgeir L.;Holzapfel, Christina;Hottenga, Jouke Jan;Huang, Jie;Huang, Tao;Hui, Jennie;Huth, Cornelia;Hutri-Kähönen, Nina;James, Alan L.;Jansson, John-Olov;Jhun, Min A.;Juonala, Markus;Kinnunen, Leena;Koistinen, Heikki A.;Kolcic, Ivana;Komulainen, Pirjo;Kuusisto, Johanna;Kvaløy, Kirsti;Kähönen, Mika;Lakka, Timo A.;Launer, Lenore J.;Lehne, Benjamin;Lindgren, Cecilia M.;Lorentzon, Mattias;Luben, Robert;Marre, Michel;Milaneschi, Yuri;Monda, Keri L.;Montgomery, Grant W.;De Moor, Marleen H. M.;Mulas, Antonella;Müller-Nurasyid, Martina;Musk, A. W.;Männikkö, Reija;Männistö, Satu;Narisu, Narisu;Nauck, Matthias;Nettleton, Jennifer A.;Nolte, Ilja M.;Oldehinkel, Albertine J.;Olden, Matthias;Ong, Ken K.;Padmanabhan, Sandosh;Paternoster, Lavinia;Perez, Jeremiah;Perola, Markus;Peters, Annette;Peters, Ulrike;Peyser, Patricia A.;Prokopenko, Inga;Puolijoki, Hannu;Raitakari, Olli T.;Rankinen, Tuomo;Rasmussen-Torvik, Laura J.;Rawal, Rajesh;Ridker, Paul M.;Rose, Lynda M.;Rudan, Igor;Sarti, Cinzia;Sarzynski, Mark A.;Savonen, Kai;Scott, William R.;Sanna, Serena;Shuldiner, Alan R.;Sidney, Steve;Silbernagel, Günther;Smith, Blair H.;Smith, Jennifer A.;Snieder, Harold;Stančáková, Alena;Sternfeld, Barbara;Swift, Amy J.;Tammelin, Tuija;Tan, Sian-Tsung;Thorand, Barbara;Thuillier, Dorothée;Vandenput, Liesbeth;Vestergaard, Henrik;van Vliet-Ostaptchouk, Jana V.;Vohl, Marie-Claude;Völker, Uwe;Waeber, Gérard;Walker, Mark;Wild, Sarah;Wong, Andrew;Wright, Alan F.;Zillikens, M. Carola;Zubair, Niha;Haiman, Christopher A.;Lemarchand, Loic;Gyllensten, Ulf;Ohlsson, Claes;Hofman, Albert;Rivadeneira, Fernando;Uitterlinden, André G.;Pérusse, Louis;Wilson, James F.;Hayward, Caroline;Polasek, Ozren;Cucca, Francesco;Hveem, Kristian;Hartman, Catharina A.;Tönjes, Anke;Bandinelli, Stefania;Palmer, Lyle J.;Kardia, Sharon L. R.;Rauramaa, Rainer;Sørensen, Thorkild I. A.;Tuomilehto, Jaakko;Salomaa, Veikko;Penninx, Brenda W. J. H.;de Geus, Eco J. C.;Boomsma, Dorret I.;Lehtimäki, Terho;Mangino, Massimo;Laakso, Markku;Bouchard, Claude;Martin, Nicholas G.;Kuh, Diana;Liu, Yongmei;Linneberg, Allan;März, Winfried;Strauch, Konstantin;Kivimäki, Mika;Harris, Tamara B.;Gudnason, Vilmundur;Völzke, Henry;Qi, Lu;Järvelin, Marjo-Riitta;Chambers, John C.;Kooner, Jaspal S.;Froguel, Philippe;Kooperberg, Charles;Vollenweider, Peter;Hallmans, Göran;Hansen, Torben;Pedersen, Oluf;Metspalu, Andres;Wareham, Nicholas J.;Langenberg, Claudia;Weir, David R.;Porteous, David J.;Boerwinkle, Eric;Chasman, Daniel I.;Abecasis, Gonçalo R.;Barroso, Inês;McCarthy, Mark I.;Frayling, Timothy M.;O’Connell, Jeffrey R.;van Duijn, Cornelia M.;Boehnke, Michael;Heid, Iris M.;Mohlke, Karen L.;Strachan, David P.;Fox, Caroline S.;Liu, Ching-Ti;Hirschhorn, Joel N.;Klein, Robert J.;Johnson, Andrew D.;Borecki, Ingrid B.;Franks, Paul W.;North, Kari E.;Cupples, L. Adrienne;Loos, Ruth J. F.;Kilpeläinen, Tuomas O.
Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumfer...
Ng, Maggie C. Y.;Graff, Mariaelisa;Lu, Yingchang;Justice, Anne E.;Mudgal, Poorva;Liu, Ching-Ti;Young, Kristin;Yanek, Lisa R.;Feitosa, Mary F.;Wojczynski, Mary K.;Rand, Kristin;Brody, Jennifer A.;Cade, Brian E.;Dimitrov, Latchezar;Duan, Qing;Guo, Xiuqing;Lange, Leslie A.;Nalls, Michael A.;Okut, Hayrettin;Tajuddin, Salman M.;Tayo, Bamidele O.;Vedantam, Sailaja;Bradfield, Jonathan P.;Chen, Guanjie;Chen, Wei-Min;Chesi, Alessandra;Irvin, Marguerite R.;Padhukasahasram, Badri;Smith, Jennifer A.;Zheng, Wei;Allison, Matthew A.;Ambrosone, Christine B.;Bandera, Elisa V.;Bartz, Traci M.;Berndt, Sonja I.;Bernstein, Leslie;Blot, William J.;Bottinger, Erwin P.;Carpten, John;Chanock, Stephen J.;Chen, Yii-Der Ida;Conti, David V.;Cooper, Richard S.;Fornage, Myriam;Freedman, Barry I.;Garcia, Melissa;Goodman, Phyllis J.;Hsu, Yu-Han H.;Hu, Jennifer;Huff, Chad D.;Ingles, Sue A.;John, Esther M.;Kittles, Rick;Klein, Eric;Li, Jin;McKnight, Barbara;Nayak, Uma;Nemesure, Barbara;Ogunniyi, Adesola;Olshan, Andrew;Press, Michael F.;Rohde, Rebecca;Rybicki, Benjamin A.;Salako, Babatunde;Sanderson, Maureen;Shao, Yaming;Siscovick, David S.;Stanford, Janet L.;Stevens, Victoria L.;Stram, Alex;Strom, Sara S.;Vaidya, Dhananjay;Witte, John S.;Yao, Jie;Zhu, Xiaofeng;Ziegler, Regina G.;Zonderman, Alan B.;Adeyemo, Adebowale;Ambs, Stefan;Cushman, Mary;Faul, Jessica D.;Hakonarson, Hakon;Levin, Albert M.;Nathanson, Katherine L.;Ware, Erin B.;Weir, David R.;Zhao, Wei;Zhi, Degui;Arnett, Donna K.;Grant, Struan F. A.;Kardia, Sharon L. R.;Oloapde, Olufunmilayo I.;Rao, D. C.;Rotimi, Charles N.;Sale, Michele M.;Williams, L. Keoki;Zemel, Babette S.;Becker, Diane M.;Borecki, Ingrid B.;Evans, Michele K.;Harris, Tamara B.;Hirschhorn, Joel N.;Li, Yun;Patel, Sanjay R.;Psaty, Bruce M.;Rotter, Jerome I.;Wilson, James G.;Bowden, Donald W.;Cupples, L. Adrienne;Haiman, Christopher A.;Loos, Ruth J. F.;North, Kari E.
Genome-wide association studies (GWAS) have identified >300 loci associated with measures of adiposity including body mass index (BMI) and waist-to-hip ratio (adjusted for BMI, WHRadjBMI), but few have been identified through screening of the African...
Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify...
Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify...