ARTICLES
9 Article(s)
Document(s)
Title
Age-related variations in DNA methylation have been reported; however, the functional relevance of these differentially methylated sites (age-dMS) are unclear. Here we report potentially functional age-dMS, defined as age-and cis-gene expression-asso...
Little is known regarding the epigenetic basis of atherosclerosis. Here we present the CD14+ blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis. The transcriptome signature includes transcription coactivator, ...
Little is known regarding the epigenetic basis of atherosclerosis. Here we present the CD14+ blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis. The transcriptome signature includes transcription coactivator, ...
Feitosa, Mary F.;Kraja, Aldi T.;Chasman, Daniel I.;Sung, Yun J.;Winkler, Thomas W.;Ntalla, Ioanna;Guo, Xiuqing;Franceschini, Nora;Cheng, Ching-Yu;Sim, Xueling;Vojinovic, Dina;Marten, Jonathan;Musani, Solomon K.;Li, Changwei;Bentley, Amy R.;Brown, Michael R.;Schwander, Karen;Richard, Melissa A.;Noordam, Raymond;Aschard, Hugues;Bartz, Traci M.;Bielak, Lawrence F.;Dorajoo, Rajkumar;Fisher, Virginia;Hartwig, Fernando P.;Horimoto, Andrea R. V. R.;Lohman, Kurt K.;Manning, Alisa K.;Rankinen, Tuomo;Smith, Albert V.;Tajuddin, Salman M.;Wojczynski, Mary K.;Alver, Maris;Boissel, Mathilde;Cai, Qiuyin;Campbell, Archie;Chai, Jin Fang;Chen, Xu;Divers, Jasmin;Gao, Chuan;Goel, Anuj;Hagemeijer, Yanick;Harris, Sarah E.;He, Meian;Hsu, Fang-Chi;Jackson, Anne U.;Kähönen, Mika;Kasturiratne, Anuradhani;Komulainen, Pirjo;Kühnel, Brigitte;Laguzzi, Federica;Luan, Jian'an;Matoba, Nana;Nolte, Ilja M.;Padmanabhan, Sandosh;Riaz, Muhammad;Rueedi, Rico;Robino, Antonietta;Said, M. Abdullah;Scott, Robert A.;Sofer, Tamar;Stančáková, Alena;Takeuchi, Fumihiko;Tayo, Bamidele O.;van der Most, Peter J.;Varga, Tibor V.;Vitart, Veronique;Wang, Yajuan;Ware, Erin B.;Warren, Helen R.;Weiss, Stefan;Wen, Wanqing;Yanek, Lisa R.;Zhang, Weihua;Zhao, Jing Hua;Afaq, Saima;Amin, Najaf;Amini, Marzyeh;Arking, Dan E.;Aung, Tin;Boerwinkle, Eric;Borecki, Ingrid;Broeckel, Ulrich;Brown, Morris;Brumat, Marco;Burke, Gregory L.;Canouil, Mickaël;Chakravarti, Aravinda;Charumathi, Sabanayagam;Ida Chen, Yii-Der;Connell, John M.;Correa, Adolfo;de las Fuentes, Lisa;de Mutsert, Renée;de Silva, H. Janaka;Deng, Xuan;Ding, Jingzhong;Duan, Qing;Eaton, Charles B.;Ehret, Georg;Eppinga, Ruben N.;Evangelou, Evangelos;Faul, Jessica D.;Felix, Stephan B.;Forouhi, Nita G.;Forrester, Terrence;Franco, Oscar H.;Friedlander, Yechiel;Gandin, Ilaria;Gao, He;Ghanbari, Mohsen;Gigante, Bruna;Gu, C. Charles;Gu, Dongfeng;Hagenaars, Saskia P.;Hallmans, Göran;Harris, Tamara B.;He, Jiang;Heikkinen, Sami;Heng, Chew-Kiat;Hirata, Makoto;Howard, Barbara V.;Ikram, M. Arfan;John, Ulrich;Katsuya, Tomohiro;Khor, Chiea Chuen;Kilpeläinen, Tuomas O.;Koh, Woon-Puay;Krieger, José E.;Kritchevsky, Stephen B.;Kubo, Michiaki;Kuusisto, Johanna;Lakka, Timo A.;Langefeld, Carl D.;Langenberg, Claudia;Launer, Lenore J.;Lehne, Benjamin;Lewis, Cora E.;Li, Yize;Lin, Shiow;Liu, Jianjun;Liu, Jingmin;Loh, Marie;Louie, Tin;Mägi, Reedik;McKenzie, Colin A.;Meitinger, Thomas;Metspalu, Andres;Milaneschi, Yuri;Milani, Lili;Mohlke, Karen L.;Momozawa, Yukihide;Nalls, Mike A.;Nelson, Christopher P.;Sotoodehnia, Nona;Norris, Jill M.;O'Connell, Jeff R.;Palmer, Nicholette D.;Perls, Thomas;Pedersen, Nancy L.;Peters, Annette;Peyser, Patricia A.;Poulter, Neil;Raffel, Leslie J.;Raitakari, Olli T.;Roll, Kathryn;Rose, Lynda M.;Rosendaal, Frits R.;Rotter, Jerome I.;Schmidt, Carsten O.;Schreiner, Pamela J.;Schupf, Nicole;Scott, William R.;Sever, Peter S.;Shi, Yuan;Sidney, Stephen;Sims, Mario;Sitlani, Colleen M.;Smith, Jennifer A.;Snieder, Harold;Starr, John M.;Strauch, Konstantin;Stringham, Heather M.;Tan, Nicholas Y. Q.;Tang, Hua;Taylor, Kent D.;Teo, Yik Ying;Tham, Yih Chung;Turner, Stephen T.;Uitterlinden, André G.;Vollenweider, Peter;Waldenberger, Melanie;Wang, Lihua;Wang, Ya Xing;Wei, Wen Bin;Williams, Christine;Yao, Jie;Yu, Caizheng;Yuan, Jian-Min;Zhao, Wei;Zonderman, Alan B.;Becker, Diane M.;Boehnke, Michael;Bowden, Donald W.;Chambers, John C.;Deary, Ian J.;Esko, Tõnu;Farrall, Martin;Franks, Paul W.;Freedman, Barry I.;Froguel, Philippe;Gasparini, Paolo;Gieger, Christian;Jonas, Jost Bruno;Kamatani, Yoichiro;Kato, Norihiro;Kooner, Jaspal S.;Kutalik, Zoltán;Laakso, Markku;Laurie, Cathy C.;Leander, Karin;Lehtimäki, Terho;Study, Lifelines Cohort;Magnusson, Patrik K. E.;Oldehinkel, Albertine J.;Penninx, Brenda W. J. H.;Polasek, Ozren;Porteous, David J.;Rauramaa, Rainer;Samani, Nilesh J.;Scott, James;Shu, Xiao-Ou;van der Harst, Pim;Wagenknecht, Lynne E.;Wareham, Nicholas J.;Watkins, Hugh;Weir, David R.;Wickremasinghe, Ananda R.;Wu, Tangchun;Zheng, Wei;Bouchard, Claude;Christensen, Kaare;Evans, Michele K.;Gudnason, Vilmundur;Horta, Bernardo L.;Kardia, Sharon L. R.;Liu, Yongmei;Pereira, Alexandre C.;Psaty, Bruce M.;Ridker, Paul M.;van Dam, Rob M.;Gauderman, W. James;Zhu, Xiaofeng;Mook-Kanamori, Dennis O.;Fornage, Myriam;Rotimi, Charles N.;Cupples, L. Adrienne;Kelly, Tanika N.;Fox, Ervin R.;Hayward, Caroline;van Duijn, Cornelia M.;Tai, E Shyong;Wong, Tien Yin;Kooperberg, Charles;Palmas, Walter;Rice, Kenneth;Morrison, Alanna C.;Elliott, Paul;Caulfield, Mark J.;Munroe, Patricia B.;Rao, Dabeeru C.;Province, Michael A.;Levy, Daniel
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcoh...
Feitosa, Mary F.;Kraja, Aldi T.;Chasman, Daniel I.;Sung, Yun J.;Winkler, Thomas W.;Ntalla, Ioanna;Guo, Xiuqing;Franceschini, Nora;Cheng, Ching-Yu;Sim, Xueling;Vojinovic, Dina;Marten, Jonathan;Musani, Solomon K.;Li, Changwei;Bentley, Amy R.;Brown, Michael R.;Schwander, Karen;Richard, Melissa A.;Noordam, Raymond;Aschard, Hugues;Bartz, Traci M.;Bielak, Lawrence F.;Dorajoo, Rajkumar;Fisher, Virginia;Hartwig, Fernando P.;Horimoto, Andrea R. V. R.;Lohman, Kurt K.;Manning, Alisa K.;Rankinen, Tuomo;Smith, Albert V.;Tajuddin, Salman M.;Wojczynski, Mary K.;Alver, Maris;Boissel, Mathilde;Cai, Qiuyin;Campbell, Archie;Chai, Jin Fang;Chen, Xu;Divers, Jasmin;Gao, Chuan;Goel, Anuj;Hagemeijer, Yanick;Harris, Sarah E.;He, Meian;Hsu, Fang-Chi;Jackson, Anne U.;Kähönen, Mika;Kasturiratne, Anuradhani;Komulainen, Pirjo;Kühnel, Brigitte;Laguzzi, Federica;Luan, Jian'an;Matoba, Nana;Nolte, Ilja M.;Padmanabhan, Sandosh;Riaz, Muhammad;Rueedi, Rico;Robino, Antonietta;Said, M. Abdullah;Scott, Robert A.;Sofer, Tamar;Stančáková, Alena;Takeuchi, Fumihiko;Tayo, Bamidele O.;van der Most, Peter J.;Varga, Tibor V.;Vitart, Veronique;Wang, Yajuan;Ware, Erin B.;Warren, Helen R.;Weiss, Stefan;Wen, Wanqing;Yanek, Lisa R.;Zhang, Weihua;Zhao, Jing Hua;Afaq, Saima;Amin, Najaf;Amini, Marzyeh;Arking, Dan E.;Aung, Tin;Boerwinkle, Eric;Borecki, Ingrid;Broeckel, Ulrich;Brown, Morris;Brumat, Marco;Burke, Gregory L.;Canouil, Mickaël;Chakravarti, Aravinda;Charumathi, Sabanayagam;Ida Chen, Yii-Der;Connell, John M.;Correa, Adolfo;de las Fuentes, Lisa;de Mutsert, Renée;de Silva, H. Janaka;Deng, Xuan;Ding, Jingzhong;Duan, Qing;Eaton, Charles B.;Ehret, Georg;Eppinga, Ruben N.;Evangelou, Evangelos;Faul, Jessica D.;Felix, Stephan B.;Forouhi, Nita G.;Forrester, Terrence;Franco, Oscar H.;Friedlander, Yechiel;Gandin, Ilaria;Gao, He;Ghanbari, Mohsen;Gigante, Bruna;Gu, C. Charles;Gu, Dongfeng;Hagenaars, Saskia P.;Hallmans, Göran;Harris, Tamara B.;He, Jiang;Heikkinen, Sami;Heng, Chew-Kiat;Hirata, Makoto;Howard, Barbara V.;Ikram, M. Arfan;John, Ulrich;Katsuya, Tomohiro;Khor, Chiea Chuen;Kilpeläinen, Tuomas O.;Koh, Woon-Puay;Krieger, José E.;Kritchevsky, Stephen B.;Kubo, Michiaki;Kuusisto, Johanna;Lakka, Timo A.;Langefeld, Carl D.;Langenberg, Claudia;Launer, Lenore J.;Lehne, Benjamin;Lewis, Cora E.;Li, Yize;Lin, Shiow;Liu, Jianjun;Liu, Jingmin;Loh, Marie;Louie, Tin;Mägi, Reedik;McKenzie, Colin A.;Meitinger, Thomas;Metspalu, Andres;Milaneschi, Yuri;Milani, Lili;Mohlke, Karen L.;Momozawa, Yukihide;Nalls, Mike A.;Nelson, Christopher P.;Sotoodehnia, Nona;Norris, Jill M.;O'Connell, Jeff R.;Palmer, Nicholette D.;Perls, Thomas;Pedersen, Nancy L.;Peters, Annette;Peyser, Patricia A.;Poulter, Neil;Raffel, Leslie J.;Raitakari, Olli T.;Roll, Kathryn;Rose, Lynda M.;Rosendaal, Frits R.;Rotter, Jerome I.;Schmidt, Carsten O.;Schreiner, Pamela J.;Schupf, Nicole;Scott, William R.;Sever, Peter S.;Shi, Yuan;Sidney, Stephen;Sims, Mario;Sitlani, Colleen M.;Smith, Jennifer A.;Snieder, Harold;Starr, John M.;Strauch, Konstantin;Stringham, Heather M.;Tan, Nicholas Y. Q.;Tang, Hua;Taylor, Kent D.;Teo, Yik Ying;Tham, Yih Chung;Turner, Stephen T.;Uitterlinden, André G.;Vollenweider, Peter;Waldenberger, Melanie;Wang, Lihua;Wang, Ya Xing;Wei, Wen Bin;Williams, Christine;Yao, Jie;Yu, Caizheng;Yuan, Jian-Min;Zhao, Wei;Zonderman, Alan B.;Becker, Diane M.;Boehnke, Michael;Bowden, Donald W.;Chambers, John C.;Deary, Ian J.;Esko, Tõnu;Farrall, Martin;Franks, Paul W.;Freedman, Barry I.;Froguel, Philippe;Gasparini, Paolo;Gieger, Christian;Jonas, Jost Bruno;Kamatani, Yoichiro;Kato, Norihiro;Kooner, Jaspal S.;Kutalik, Zoltán;Laakso, Markku;Laurie, Cathy C.;Leander, Karin;Lehtimäki, Terho;Study, Lifelines Cohort;Magnusson, Patrik K. E.;Oldehinkel, Albertine J.;Penninx, Brenda W. J. H.;Polasek, Ozren;Porteous, David J.;Rauramaa, Rainer;Samani, Nilesh J.;Scott, James;Shu, Xiao-Ou;van der Harst, Pim;Wagenknecht, Lynne E.;Wareham, Nicholas J.;Watkins, Hugh;Weir, David R.;Wickremasinghe, Ananda R.;Wu, Tangchun;Zheng, Wei;Bouchard, Claude;Christensen, Kaare;Evans, Michele K.;Gudnason, Vilmundur;Horta, Bernardo L.;Kardia, Sharon L. R.;Liu, Yongmei;Pereira, Alexandre C.;Psaty, Bruce M.;Ridker, Paul M.;van Dam, Rob M.;Gauderman, W. James;Zhu, Xiaofeng;Mook-Kanamori, Dennis O.;Fornage, Myriam;Rotimi, Charles N.;Cupples, L. Adrienne;Kelly, Tanika N.;Fox, Ervin R.;Hayward, Caroline;van Duijn, Cornelia M.;Tai, E Shyong;Wong, Tien Yin;Kooperberg, Charles;Palmas, Walter;Rice, Kenneth;Morrison, Alanna C.;Elliott, Paul;Caulfield, Mark J.;Munroe, Patricia B.;Rao, Dabeeru C.;Province, Michael A.;Levy, Daniel
Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP) regulation remains unknown. We hypothesized that a genome-wide association study accounting for gene-alcoh...
Graff, Mariaelisa;Scott, Robert A.;Justice, Anne E.;Young, Kristin L.;Feitosa, Mary F.;Barata, Llilda;Winkler, Thomas W.;Chu, Audrey Y.;Mahajan, Anubha;Hadley, David;Xue, Luting;Workalemahu, Tsegaselassie;Heard-Costa, Nancy L.;den Hoed, Marcel;Ahluwalia, Tarunveer S.;Qi, Qibin;Ngwa, Julius S.;Renström, Frida;Quaye, Lydia;Eicher, John D.;Hayes, James E.;Cornelis, Marilyn;Kutalik, Zoltan;Lim, Elise;Luan, Jian’an;Huffman, Jennifer E.;Zhang, Weihua;Zhao, Wei;Griffin, Paula J.;Haller, Toomas;Ahmad, Shafqat;Marques-Vidal, Pedro M.;Bien, Stephanie;Yengo, Loic;Teumer, Alexander;Smith, Albert Vernon;Kumari, Meena;Harder, Marie Neergaard;Justesen, Johanne Marie;Kleber, Marcus E.;Hollensted, Mette;Lohman, Kurt;Rivera, Natalia V.;Whitfield, John B.;Zhao, Jing Hua;Stringham, Heather M.;Lyytikäinen, Leo-Pekka;Huppertz, Charlotte;Willemsen, Gonneke;Peyrot, Wouter J.;Wu, Ying;Kristiansson, Kati;Demirkan, Ayse;Fornage, Myriam;Hassinen, Maija;Bielak, Lawrence F.;Cadby, Gemma;Tanaka, Toshiko;Mägi, Reedik;van der Most, Peter J.;Jackson, Anne U.;Bragg-Gresham, Jennifer L.;Vitart, Veronique;Marten, Jonathan;Navarro, Pau;Bellis, Claire;Pasko, Dorota;Johansson, Åsa;Snitker, Søren;Cheng, Yu-Ching;Eriksson, Joel;Lim, Unhee;Aadahl, Mette;Adair, Linda S.;Amin, Najaf;Balkau, Beverley;Auvinen, Juha;Beilby, John;Bergman, Richard N.;Bergmann, Sven;Bertoni, Alain G.;Blangero, John;Bonnefond, Amélie;Bonnycastle, Lori L.;Borja, Judith B.;Brage, Søren;Busonero, Fabio;Buyske, Steve;Campbell, Harry;Chines, Peter S.;Collins, Francis S.;Corre, Tanguy;Smith, George Davey;Delgado, Graciela E.;Dueker, Nicole;Dörr, Marcus;Ebeling, Tapani;Eiriksdottir, Gudny;Esko, Tõnu;Faul, Jessica D.;Fu, Mao;Færch, Kristine;Gieger, Christian;Gläser, Sven;Gong, Jian;Gordon-Larsen, Penny;Grallert, Harald;Grammer, Tanja B.;Grarup, Niels;van Grootheest, Gerard;Harald, Kennet;Hastie, Nicholas D.;Havulinna, Aki S.;Hernandez, Dena;Hindorff, Lucia;Hocking, Lynne J.;Holmens, Oddgeir L.;Holzapfel, Christina;Hottenga, Jouke Jan;Huang, Jie;Huang, Tao;Hui, Jennie;Huth, Cornelia;Hutri-Kähönen, Nina;James, Alan L.;Jansson, John-Olov;Jhun, Min A.;Juonala, Markus;Kinnunen, Leena;Koistinen, Heikki A.;Kolcic, Ivana;Komulainen, Pirjo;Kuusisto, Johanna;Kvaløy, Kirsti;Kähönen, Mika;Lakka, Timo A.;Launer, Lenore J.;Lehne, Benjamin;Lindgren, Cecilia M.;Lorentzon, Mattias;Luben, Robert;Marre, Michel;Milaneschi, Yuri;Monda, Keri L.;Montgomery, Grant W.;De Moor, Marleen H. M.;Mulas, Antonella;Müller-Nurasyid, Martina;Musk, A. W.;Männikkö, Reija;Männistö, Satu;Narisu, Narisu;Nauck, Matthias;Nettleton, Jennifer A.;Nolte, Ilja M.;Oldehinkel, Albertine J.;Olden, Matthias;Ong, Ken K.;Padmanabhan, Sandosh;Paternoster, Lavinia;Perez, Jeremiah;Perola, Markus;Peters, Annette;Peters, Ulrike;Peyser, Patricia A.;Prokopenko, Inga;Puolijoki, Hannu;Raitakari, Olli T.;Rankinen, Tuomo;Rasmussen-Torvik, Laura J.;Rawal, Rajesh;Ridker, Paul M.;Rose, Lynda M.;Rudan, Igor;Sarti, Cinzia;Sarzynski, Mark A.;Savonen, Kai;Scott, William R.;Sanna, Serena;Shuldiner, Alan R.;Sidney, Steve;Silbernagel, Günther;Smith, Blair H.;Smith, Jennifer A.;Snieder, Harold;Stančáková, Alena;Sternfeld, Barbara;Swift, Amy J.;Tammelin, Tuija;Tan, Sian-Tsung;Thorand, Barbara;Thuillier, Dorothée;Vandenput, Liesbeth;Vestergaard, Henrik;van Vliet-Ostaptchouk, Jana V.;Vohl, Marie-Claude;Völker, Uwe;Waeber, Gérard;Walker, Mark;Wild, Sarah;Wong, Andrew;Wright, Alan F.;Zillikens, M. Carola;Zubair, Niha;Haiman, Christopher A.;Lemarchand, Loic;Gyllensten, Ulf;Ohlsson, Claes;Hofman, Albert;Rivadeneira, Fernando;Uitterlinden, André G.;Pérusse, Louis;Wilson, James F.;Hayward, Caroline;Polasek, Ozren;Cucca, Francesco;Hveem, Kristian;Hartman, Catharina A.;Tönjes, Anke;Bandinelli, Stefania;Palmer, Lyle J.;Kardia, Sharon L. R.;Rauramaa, Rainer;Sørensen, Thorkild I. A.;Tuomilehto, Jaakko;Salomaa, Veikko;Penninx, Brenda W. J. H.;de Geus, Eco J. C.;Boomsma, Dorret I.;Lehtimäki, Terho;Mangino, Massimo;Laakso, Markku;Bouchard, Claude;Martin, Nicholas G.;Kuh, Diana;Liu, Yongmei;Linneberg, Allan;März, Winfried;Strauch, Konstantin;Kivimäki, Mika;Harris, Tamara B.;Gudnason, Vilmundur;Völzke, Henry;Qi, Lu;Järvelin, Marjo-Riitta;Chambers, John C.;Kooner, Jaspal S.;Froguel, Philippe;Kooperberg, Charles;Vollenweider, Peter;Hallmans, Göran;Hansen, Torben;Pedersen, Oluf;Metspalu, Andres;Wareham, Nicholas J.;Langenberg, Claudia;Weir, David R.;Porteous, David J.;Boerwinkle, Eric;Chasman, Daniel I.;Abecasis, Gonçalo R.;Barroso, Inês;McCarthy, Mark I.;Frayling, Timothy M.;O’Connell, Jeffrey R.;van Duijn, Cornelia M.;Boehnke, Michael;Heid, Iris M.;Mohlke, Karen L.;Strachan, David P.;Fox, Caroline S.;Liu, Ching-Ti;Hirschhorn, Joel N.;Klein, Robert J.;Johnson, Andrew D.;Borecki, Ingrid B.;Franks, Paul W.;North, Kari E.;Cupples, L. Adrienne;Loos, Ruth J. F.;Kilpeläinen, Tuomas O.
Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumfer...
Graff, Mariaelisa;Scott, Robert A.;Justice, Anne E.;Young, Kristin L.;Feitosa, Mary F.;Barata, Llilda;Winkler, Thomas W.;Chu, Audrey Y.;Mahajan, Anubha;Hadley, David;Xue, Luting;Workalemahu, Tsegaselassie;Heard-Costa, Nancy L.;den Hoed, Marcel;Ahluwalia, Tarunveer S.;Qi, Qibin;Ngwa, Julius S.;Renström, Frida;Quaye, Lydia;Eicher, John D.;Hayes, James E.;Cornelis, Marilyn;Kutalik, Zoltan;Lim, Elise;Luan, Jian’an;Huffman, Jennifer E.;Zhang, Weihua;Zhao, Wei;Griffin, Paula J.;Haller, Toomas;Ahmad, Shafqat;Marques-Vidal, Pedro M.;Bien, Stephanie;Yengo, Loic;Teumer, Alexander;Smith, Albert Vernon;Kumari, Meena;Harder, Marie Neergaard;Justesen, Johanne Marie;Kleber, Marcus E.;Hollensted, Mette;Lohman, Kurt;Rivera, Natalia V.;Whitfield, John B.;Zhao, Jing Hua;Stringham, Heather M.;Lyytikäinen, Leo-Pekka;Huppertz, Charlotte;Willemsen, Gonneke;Peyrot, Wouter J.;Wu, Ying;Kristiansson, Kati;Demirkan, Ayse;Fornage, Myriam;Hassinen, Maija;Bielak, Lawrence F.;Cadby, Gemma;Tanaka, Toshiko;Mägi, Reedik;van der Most, Peter J.;Jackson, Anne U.;Bragg-Gresham, Jennifer L.;Vitart, Veronique;Marten, Jonathan;Navarro, Pau;Bellis, Claire;Pasko, Dorota;Johansson, Åsa;Snitker, Søren;Cheng, Yu-Ching;Eriksson, Joel;Lim, Unhee;Aadahl, Mette;Adair, Linda S.;Amin, Najaf;Balkau, Beverley;Auvinen, Juha;Beilby, John;Bergman, Richard N.;Bergmann, Sven;Bertoni, Alain G.;Blangero, John;Bonnefond, Amélie;Bonnycastle, Lori L.;Borja, Judith B.;Brage, Søren;Busonero, Fabio;Buyske, Steve;Campbell, Harry;Chines, Peter S.;Collins, Francis S.;Corre, Tanguy;Smith, George Davey;Delgado, Graciela E.;Dueker, Nicole;Dörr, Marcus;Ebeling, Tapani;Eiriksdottir, Gudny;Esko, Tõnu;Faul, Jessica D.;Fu, Mao;Færch, Kristine;Gieger, Christian;Gläser, Sven;Gong, Jian;Gordon-Larsen, Penny;Grallert, Harald;Grammer, Tanja B.;Grarup, Niels;van Grootheest, Gerard;Harald, Kennet;Hastie, Nicholas D.;Havulinna, Aki S.;Hernandez, Dena;Hindorff, Lucia;Hocking, Lynne J.;Holmens, Oddgeir L.;Holzapfel, Christina;Hottenga, Jouke Jan;Huang, Jie;Huang, Tao;Hui, Jennie;Huth, Cornelia;Hutri-Kähönen, Nina;James, Alan L.;Jansson, John-Olov;Jhun, Min A.;Juonala, Markus;Kinnunen, Leena;Koistinen, Heikki A.;Kolcic, Ivana;Komulainen, Pirjo;Kuusisto, Johanna;Kvaløy, Kirsti;Kähönen, Mika;Lakka, Timo A.;Launer, Lenore J.;Lehne, Benjamin;Lindgren, Cecilia M.;Lorentzon, Mattias;Luben, Robert;Marre, Michel;Milaneschi, Yuri;Monda, Keri L.;Montgomery, Grant W.;De Moor, Marleen H. M.;Mulas, Antonella;Müller-Nurasyid, Martina;Musk, A. W.;Männikkö, Reija;Männistö, Satu;Narisu, Narisu;Nauck, Matthias;Nettleton, Jennifer A.;Nolte, Ilja M.;Oldehinkel, Albertine J.;Olden, Matthias;Ong, Ken K.;Padmanabhan, Sandosh;Paternoster, Lavinia;Perez, Jeremiah;Perola, Markus;Peters, Annette;Peters, Ulrike;Peyser, Patricia A.;Prokopenko, Inga;Puolijoki, Hannu;Raitakari, Olli T.;Rankinen, Tuomo;Rasmussen-Torvik, Laura J.;Rawal, Rajesh;Ridker, Paul M.;Rose, Lynda M.;Rudan, Igor;Sarti, Cinzia;Sarzynski, Mark A.;Savonen, Kai;Scott, William R.;Sanna, Serena;Shuldiner, Alan R.;Sidney, Steve;Silbernagel, Günther;Smith, Blair H.;Smith, Jennifer A.;Snieder, Harold;Stančáková, Alena;Sternfeld, Barbara;Swift, Amy J.;Tammelin, Tuija;Tan, Sian-Tsung;Thorand, Barbara;Thuillier, Dorothée;Vandenput, Liesbeth;Vestergaard, Henrik;van Vliet-Ostaptchouk, Jana V.;Vohl, Marie-Claude;Völker, Uwe;Waeber, Gérard;Walker, Mark;Wild, Sarah;Wong, Andrew;Wright, Alan F.;Zillikens, M. Carola;Zubair, Niha;Haiman, Christopher A.;Lemarchand, Loic;Gyllensten, Ulf;Ohlsson, Claes;Hofman, Albert;Rivadeneira, Fernando;Uitterlinden, André G.;Pérusse, Louis;Wilson, James F.;Hayward, Caroline;Polasek, Ozren;Cucca, Francesco;Hveem, Kristian;Hartman, Catharina A.;Tönjes, Anke;Bandinelli, Stefania;Palmer, Lyle J.;Kardia, Sharon L. R.;Rauramaa, Rainer;Sørensen, Thorkild I. A.;Tuomilehto, Jaakko;Salomaa, Veikko;Penninx, Brenda W. J. H.;de Geus, Eco J. C.;Boomsma, Dorret I.;Lehtimäki, Terho;Mangino, Massimo;Laakso, Markku;Bouchard, Claude;Martin, Nicholas G.;Kuh, Diana;Liu, Yongmei;Linneberg, Allan;März, Winfried;Strauch, Konstantin;Kivimäki, Mika;Harris, Tamara B.;Gudnason, Vilmundur;Völzke, Henry;Qi, Lu;Järvelin, Marjo-Riitta;Chambers, John C.;Kooner, Jaspal S.;Froguel, Philippe;Kooperberg, Charles;Vollenweider, Peter;Hallmans, Göran;Hansen, Torben;Pedersen, Oluf;Metspalu, Andres;Wareham, Nicholas J.;Langenberg, Claudia;Weir, David R.;Porteous, David J.;Boerwinkle, Eric;Chasman, Daniel I.;Abecasis, Gonçalo R.;Barroso, Inês;McCarthy, Mark I.;Frayling, Timothy M.;O’Connell, Jeffrey R.;van Duijn, Cornelia M.;Boehnke, Michael;Heid, Iris M.;Mohlke, Karen L.;Strachan, David P.;Fox, Caroline S.;Liu, Ching-Ti;Hirschhorn, Joel N.;Klein, Robert J.;Johnson, Andrew D.;Borecki, Ingrid B.;Franks, Paul W.;North, Kari E.;Cupples, L. Adrienne;Loos, Ruth J. F.;Kilpeläinen, Tuomas O.
Physical activity (PA) may modify the genetic effects that give rise to increased risk of obesity. To identify adiposity loci whose effects are modified by PA, we performed genome-wide interaction meta-analyses of BMI and BMI-adjusted waist circumfer...
Background: Data are limited on genome-wide association studies (GWAS) for incident coronary heart disease (CHD). Moreover, it is not known whether genetic variants identified to date also associate with risk of CHD in a prospective setting. Methods:...
Vimaleswaran, Karani S;Cavadino, Alana;Berry, Diane J;Jorde, Rolf;Dieffenbach, Aida Karina;Lu, Chen;Alves, Alexessander Couto;Heerspink, Hiddo J Lambers;Tikkanen, Emmi;Eriksson, Joel;Wong, Andrew;Mangino, Massimo;Jablonski, Kathleen A;Nolte, Ilja M;Houston, Denise K;Ahluwalia, Tarunveer Singh;van der Most, Peter J;Pasko, Dorota;Zgaga, Lina;Thiering, Elisabeth;Vitart, Veronique;Fraser, Ross M;Huffman, Jennifer E;de Boer, Rudolf A;Schöttker, Ben;Saum, Kai-Uwe;McCarthy, Mark I;Dupuis, Josée;Herzig, Karl-Heinz;Sebert, Sylvain;Pouta, Anneli;Laitinen, Jaana;Kleber, Marcus E;Navis, Gerjan;Lorentzon, Mattias;Jameson, Karen;Arden, Nigel;Cooper, Jackie A;Acharya, Jayshree;Hardy, Rebecca;Raitakari, Olli;Ripatti, Samuli;Billings, Liana K;Lahti, Jari;Osmond, Clive;Penninx, Brenda W;Rejnmark, Lars;Lohman, Kurt K;Paternoster, Lavinia;Stolk, Ronald P;Hernandez, Dena G;Byberg, Liisa;Hagström, Emil;Melhus, Håkan;Ingelsson, Erik;Mellström, Dan;Ljunggren, Östen;Tzoulaki, Ioanna;McLachlan, Stela;Theodoratou, Evropi;Tiesler, Carla M T;Jula, Antti;Navarro, Pau;Wright, Alan F;Polasek, Ozren;Wilson, James F;Rudan, Igor;Salomaa, Veikko;Heinrich, Joachim;Campbell, Harry;Price, Jacqueline F;Karlsson, Magnus;Lind, Lars;Michaëlsson, Karl;Bandinelli, Stefania;Frayling, Timothy M;Hartman, Catharina A;Sørensen, Thorkild I A;Kritchevsky, Stephen B;Langdahl, Bente Lomholt;Eriksson, Johan G;Florez, Jose C;Spector, Tim D;Lehtimäki, Terho;Kuh, Diana;Humphries, Steve E;Cooper, Cyrus;Ohlsson, Claes;März, Winfried;de Borst, Martin H;Kumari, Meena;Kivimaki, Mika;Wang, Thomas J;Power, Chris;Brenner, Hermann;Grimnes, Guri;van der Harst, Pim;Snieder, Harold;Hingorani, Aroon D;Pilz, Stefan;Whittaker, John C;Järvelin, Marjo-Riitta;Hyppönen, Elina
Background Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25(...