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Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Motivation: Fine mapping is a widely used approach for identifying the causal variant(s) at disease-associated loci. Standard methods (e.g. multiple regression) require individual level genotypes. Recent fine mapping methods using summary-level data ...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Motivation: Fine mapping is a widely used approach for identifying the causal variant(s) at disease-associated loci. Standard methods (e.g. multiple regression) require individual level genotypes. Recent fine mapping methods using summary-level data ...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Wheeler, Eleanor;Leong, Aaron;Liu, Ching-Ti;Hivert, Marie-France;Strawbridge, Rona J.;Podmore, Clara;Li, Man;Yao, Jie;Sim, Xueling;Hong, Jaeyoung;Chu, Audrey Y.;Zhang, Weihua;Wang, Xu;Chen, Peng;Maruthur, Nisa M.;Porneala, Bianca C.;Sharp, Stephen J.;Jia, Yucheng;Kabagambe, Edmond K.;Chang, Li-Ching;Chen, Wei-Min;Elks, Cathy E.;Evans, Daniel S.;Fan, Qiao;Giulianini, Franco;Go, Min Jin;Hottenga, Jouke-Jan;Hu, Yao;Jackson, Anne U.;Kanoni, Stavroula;Kim, Young Jin;Kleber, Marcus E.;Ladenvall, Claes;Lecoeur, Cecile;Lim, Sing-Hui;Lu, Yingchang;Mahajan, Anubha;Marzi, Carola;Nalls, Mike A.;Navarro, Pau;Nolte, Ilja M.;Rose, Lynda M.;Rybin, Denis V.;Sanna, Serena;Shi, Yuan;Stram, Daniel O.;Takeuchi, Fumihiko;Tan, Shu Pei;van der Most, Peter J.;Van Vliet-Ostaptchouk, Jana V.;Wong, Andrew;Yengo, Loic;Zhao, Wanting;Goel, Anuj;Martinez Larrad, Maria Teresa;Radke, Dörte;Salo, Perttu;Tanaka, Toshiko;van Iperen, Erik P. A.;Abecasis, Goncalo;Afaq, Saima;Alizadeh, Behrooz Z.;Bertoni, Alain G.;Bonnefond, Amelie;Böttcher, Yvonne;Bottinger, Erwin P.;Campbell, Harry;Carlson, Olga D.;Chen, Chien-Hsiun;Cho, Yoon Shin;Garvey, W. Timothy;Gieger, Christian;Goodarzi, Mark O.;Grallert, Harald;Hamsten, Anders;Hartman, Catharina A.;Herder, Christian;Hsiung, Chao Agnes;Huang, Jie;Igase, Michiya;Isono, Masato;Katsuya, Tomohiro;Khor, Chiea-Chuen;Kiess, Wieland;Kohara, Katsuhiko;Kovacs, Peter;Lee, Juyoung;Lee, Wen-Jane;Lehne, Benjamin;Li, Huaixing;Liu, Jianjun;Lobbens, Stephane;Luan, Jian'an;Lyssenko, Valeriya;Meitinger, Thomas;Miki, Tetsuro;Miljkovic, Iva;Moon, Sanghoon;Mulas, Antonella;Müller, Gabriele;Müller-Nurasyid, Martina;Nagaraja, Ramaiah;Nauck, Matthias;Pankow, James S.;Polasek, Ozren;Prokopenko, Inga;Ramos, Paula S.;Rasmussen-Torvik, Laura;Rathmann, Wolfgang;Rich, Stephen S.;Robertson, Neil R.;Roden, Michael;Roussel, Ronan;Rudan, Igor;Scott, Robert A.;Scott, William R.;Sennblad, Bengt;Siscovick, David S.;Strauch, Konstantin;Sun, Liang;Swertz, Morris;Tajuddin, Salman M.;Taylor, Kent D.;Teo, Yik-Ying;Tham, Yih Chung;Tönjes, Anke;Wareham, Nicholas J.;Willemsen, Gonneke;Wilsgaard, Tom;Hingorani, Aroon D.;Egan, Josephine;Ferrucci, Luigi;Hovingh, G. Kees;Jula, Antti;Kivimaki, Mika;Kumari, Meena;Njølstad, Inger;Palmer, Colin N. A.;Serrano Ríos, Manuel;Stumvoll, Michael;Watkins, Hugh;Aung, Tin;Blüher, Matthias;Boehnke, Michael;Boomsma, Dorret I.;Bornstein, Stefan R.;Chambers, John C.;Chasman, Daniel I.;Chen, Yii-Der Ida;Chen, Yduan-Tsong;Cheng, Ching-Yu;Cucca, Francesco;de Geus, Eco J. C.;Deloukas, Panos;Evans, Michele K.;Fornage, Myriam;Friedlander, Yechiel;Froguel, Philippe;Groop, Leif;Gross, Myron D.;Harris, Tamara B.;Hayward, Caroline;Heng, Chew-Kiat;Ingelsson, Erik;Kato, Norihiro;Kim, Bong-Jo;Koh, Woon-Puay;Kooner, Jaspal S.;Körner, Antje;Kuh, Diana;Kuusisto, Johanna;Laakso, Markku;Lin, Xu;Liu, Yongmei;Loos, Ruth J. F.;Magnusson, Patrik K. E.;März, Winfried;McCarthy, Mark I.;Oldehinkel, Albertine J.;Ong, Ken K.;Pedersen, Nancy L.;Pereira, Mark A.;Peters, Annette;Ridker, Paul M.;Sabanayagam, Charumathi;Sale, Michele;Saleheen, Danish;Saltevo, Juha;Schwarz, Peter EH.;Sheu, Wayne H. H.;Snieder, Harold;Spector, Timothy D.;Tabara, Yasuharu;Tuomilehto, Jaakko;van Dam, Rob M.;Wilson, James G.;Wilson, James F.;Wolffenbuttel, Bruce H. R.;Wong, Tien Yin;Wu, Jer-Yuarn;Yuan, Jian-Min;Zonderman, Alan B.;Soranzo, Nicole;Guo, Xiuqing;Roberts, David J.;Florez, Jose C.;Sladek, Robert;Dupuis, Josée;Morris, Andrew P.;Tai, E-Shyong;Selvin, Elizabeth;Rotter, Jerome I.;Langenberg, Claudia;Barroso, Inês;Meigs, James B.
Background: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These varia...