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29 Article(s)
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Document(s)
Title
Motivation Fine mapping is a widely used approach for identifying the causal variant(s) at disease-associated loci. Standard methods (e.g. multiple regression) require individual level genotypes. Recent fine mapping methods using summary-level data r...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic variants as markers of exposure...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Asselbergs, Folkert W.;Guo, Yiran;van Iperen, Erik P. A.;Sivapalaratnam, Suthesh;Tragante, Vinicius;Lanktree, Matthew B.;Lange, Leslie A.;Almoguera, Berta;Appelman, Yolande E.;Barnard, John;Baumert, Jens;Beitelshees, Amber L.;Bhangale, Tushar R.;Chen, Yii-Der Ida;Gaunt, Tom R.;Gong, Yan;Hopewell, Jemma C.;Johnson, Toby;Kleber, Marcus E.;Langaee, Taimour Y.;Li, Mingyao;Li, Yun R.;Liu, Kiang;McDonough, Caitrin W.;Meijs, Matthijs El.;Middelberg, Rita P. S.;Musunuru, Kiran;Nelson, Christopher P.;O'Connell, Jeffery R.;Padmanabhan, Sandosh;Pankow, James S.;Pankratz, Nathan;Rafelt, Suzanne;Rajagopalan, Ramakrishnan;Romaine, Simon P. R.;Schork, Nicholas J.;Shaffer, Jonathan;Shen, Haiqing;Smith, Erin N.;Tischfield, Sam E.;van der Most, Peter J.;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Volcik, Kelly A.;Zhang, Li;Bailey, Kent R.;Bailey, Kristian M.;Bauer, Florianne;Boer, Jolanda M. A.;Braund, Peter S.;Burt, Amber;Burton, Paul R.;Buxbaum, Sarah G.;Chen, Wei;Cooper-DeHoff, Rhonda M.;Cupples, L. Adrienne;deJong, Jonas S.;Delles, Christian;Duggan, David;Fornage, Myriam;Furlong, Clement E.;Glazer, Nicole;Gums, John G.;Hastie, Claire;Holmes, Michael V.;Illig, Thomas;Kirkland, Susan A.;Kivimaki, Mika;Klein, Ronald;Klein, Barbara E.;Kooperberg, Charles;Kottke-Marchant, Kandice;Kumari, Meena;LaCroix, Andrea Z.;Mallela, Laya;Murugesan, Gurunathan;Ordovas, Jose;Ouwehand, Willem H.;Post, Wendy S.;Saxena, Richa;Scharnagl, Hubert;Schreiner, Pamela J.;Shah, Tina;Shields, Denis C.;Shimbo, Daichi;Srinivasan, Sathanur R.;Stolk, Ronald P.;Swerdlow, Daniel I.;Taylor, Herman A.;Topo, Eric J.;Toskala, Elina;van Pelt, Joost L.;van Setten, Jessica;Yusuf, Salim;Whittaker, John C.;Zwinderman, A. H.;Anand, Sonia S.;Balmforth, Anthony J.;Berenson, Gerald S.;Bezzina, Connie R.;Boehm, Bernhard O.;Boerwinkle, Eric;Casas, Juan P.;Caulfield, Mark J.;Clarke, Robert;Connell, John M.;Cruickshanks, Karen J.;Davidson, Karina W.;Day, Ian N. M.;de Bakker, Paul I. W.;Doevendans, Pieter A.;Dominiczak, Anna E.;Hall, Alistair S.;Hartman, Catharina A.;Hengstenberg, Christian;Hillege, Hans L.;Hofker, Marten H.;Humphries, Steve E.;Jarvik, Gail P.;Johnson, Julie A.;Kaess, Bernhard M.;Kathiresan, Sekar;Koenig, Wolfgang;Lawlor, Debbie A.;Maerz, Winfried;Melander, Olle;Mitchell, Braxton D.;Montgomery, Grant W.;Munroe, Patricia B.;Murray, Sarah S.;Newhouse, Stephen J.;Onland-Moret, N. Charlotte;Poulter, Neil;Psaty, Bruce;Redline, Susan;Rich, Stephen S.;Rotter, Jerome I.;Schunkert, Heribert;Sever, Peter;Shuldiner, Alan R.;Silverstein, Roy L.;Stanton, Alice;Thorand, Barbara;Trip, Mieke D.;Tsai, Michael Y.;van der Harst, Pim;van der Schoot, Ellen;van der Schouw, Yvonne T.;Verschuren, W. M. Monique;Watkins, Hugh;Wilde, Arthur A. M.;Wolffenbuttel, Bruce H. R.;Whitfield, John B.;Hovingh, G. Kees;Ballantyne, Christie M.;Wijmenga, Cisca;Reilly, Muredach P.;Martin, Nicholas G.;Wilson, James G.;Rader, Daniel J.;Samani, Nilesh J.;Reiner, Alex P.;Hegele, Robert A.;Kastelein, John J. P.;Hingorani, Aroon D.;Talmud, Philippa J.;Hakonarson, Hakon;Elbers, Clara C.;Keating, Brendan J.;Drenos, Fotios
Genome-wide association studies (GWASs) have identified many SNPs underlying variations in plasma-lipid levels. We explore whether additional loci associated with plasma-lipid phenotypes, such as high-density lipoprotein cholesterol (HDL-C), low-dens...
Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic variants as markers of exposure...
Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic variants as markers of exposure...