Chlorella variabilis, a symbiotic alga, is usually present in the cytoplasm of Paramecium bursaria, although it can be cultured in host-free conditions. Morphological and chemical properties of its cell wall were compared between its free-living and ...
We are pushing forward with the GRAINE project, a 10-MeV to 100-GeV cosmic γ-ray observation project that uses an emulsion telescope with high angular resolution (0.08° at 1–2 GeV) and polarization sensitivity, and a large aperture area (∼10 m(2)), b...
Yatabe, Tomoaki;Inoue, Shigeaki;Sakamoto, So;Sumi, Yuka;Nishida, Osamu;Hayashida, Kei;Hara, Yoshitaka;Fukuda, Tatsuma;Matsushima, Asako;Matsuda, Akihisa;Yasuda, Hideto;Yamashita, Kazuto;Egi, Moritoki Introduction: The benefits and harm caused by anticoagulant treatments for sepsis induced disseminated intravascular coagulation (DIC) remain unclear. Therefore, we performed a network meta-analysis to assess the effect of available anticoagulant tre...
Relationship lending is broadly interpreted as a strong partnership between a lender and a borrower. Nevertheless, we still lack consensus regarding how to quantify the strength of a lending relationship, while simple statistics such as the frequency...
Tahara, Makoto;Schlumberger, Martin;Elisei, Rossella;Habra, Mouhammed Amir;Kiyota, Naomi;Paschke, Ralf;Dutcus, Corina E.;Hihara, Taro;McGrath, Shannon;Matijevic, Mark;Kadowaki, Tadashi;Funahashi, Yasuhiro;Sherman, Steven I. Background: Lenvatinib significantly prolonged progression-free survival (PFS) versus placebo in the phase III Study of (E7080) LEnvatinib in differentiated Cancer of the Thyroid (SELECT) of patients with radioiodine-refractory differentiated thyroid...
Namikawa, Kenjiro;Kiyohara, Yoshio;Takenouchi, Tatsuya;Uhara, Hisashi;Uchi, Hiroshi;Yoshikawa, Shusuke;Takatsuka, Sumiko;Koga, Hiroshi;Wada, Naoko;Minami, Hironobu;Hatsumichi, Masahiro;Asada, Suguru;Namba, Yoshinobu;Yamazaki, Naoya Aim: The aim of the study was to evaluate the efficacy and safety of nivolumab combined with ipilimumab in treatment-naive Japanese patients with advanced melanoma. Methods: In this multicentre, single-arm study, treatment-naive Japanese patients wit...
Cancer cells rapidly consume glutamine as a carbon and nitrogen source to support proliferation, but the cell number continues to increase exponentially after glutamine is nearly depleted from the medium. In contrast, cell proliferation rates are str...
This study aims to examine an expected role of public transportation services in suburban housing development areas of Kobe City in Japan, through calculation of accessibility to the city center using a utility-based measure. The calculation results ...
Goto, Hideaki;Kiyota, Naomi;Otsuki, Naoki;Imamura, Yoshinori;Chayahara, Naoko;Suto, Hirotaka;Nagatani, Yoshiaki;Toyoda, Masanori;Mukohara, Toru;Nibu, Ken-ichi;Kasahara, Toshihiko;Ito, Yasuhiro;Miya, Akihiro;Hirokawa, Mitsuyoshi;Miyauchi, Akira;Minami, Hironobu Sorafenib and lenvatinib showed efficacy for patients with radioactive iodine (RAI)-refractory differentiated thyroid cancer (DTC) in pivotal phase 3 clinical trials. Although the efficacy of lenvatinib in patients who received previous treatment wit...
The ecosystem concept is of increasing significance in the field of the management of technology and innovation. This paper provides an overview of 90 previous studies using the ecosystem concept in this field, all published in leading academic journ...
