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During the last decade there has been a great increase in the number of noncoding RNA genes identified, including new classes such as microRNAs and piRNAs. There is also a large growth in the amount of experimental characterization of these RNA compo...
Birney, Ewan;Stamatoyannopoulos, John A.;Dutta, Anindya;Guigó, Roderic;Gingeras, Thomas R.;Margulies, Elliott H.;Weng, Zhiping;Snyder, Michael;Dermitzakis, Emmanouil T.;Thurman, Robert E.;Kuehn, Michael S.;Taylor, Christopher M.;Neph, Shane;Koch, Christoph M.;Asthana, Saurabh;Malhotra, Ankit;Adzhubei, Ivan;Greenbaum, Jason A.;Andrews, Robert M.;Flicek, Paul;Boyle, Patrick J.;Cao, Hua;Carter, Nigel P.;Clelland, Gayle K.;Davis, Sean;Day, Nathan;Dhami, Pawandeep;Dillon, Shane C.;Dorschner, Michael O.;Fiegler, Heike;Giresi, Paul G.;Goldy, Jeff;Hawrylycz, Michael;Haydock, Andrew;Humbert, Richard;James, Keith D.;Johnson, Brett E.;Johnson, Ericka M.;Frum, Tristan T.;Rosenzweig, Elizabeth R.;Karnani, Neerja;Lee, Kirsten;Lefebvre, Gregory C.;Navas, Patrick A.;Neri, Fidencio;Parker, Stephen C J;Sabo, Peter J.;Sandstrom, Richard;Shafer, Anthony;Vetrie, David;Weaver, Molly;Wilcox, Sarah;Yu, Man;Collins, Francis S.;Dekker, Job;Lieb, Jason D.;Tullius, Thomas D.;Crawford, Gregory E.;Sunyaev, Shamil;Noble, William S.;Dunham, Ian;Denoeud, France;Reymond, Alexandre;Kapranov, Philipp;Rozowsky, Joel;Zheng, Deyou;Castelo, Robert;Frankish, Adam;Harrow, Jennifer;Ghosh, Srinka;Sandelin, Albin;Hofacker, Ivo L.;Baertsch, Robert;Keefe, Damian;Dike, Sujit;Cheng, Jill;Hirsch, Heather A.;Sekinger, Edward A.;Lagarde, Julien;Abril, Josep F.;Shahab, Atif;Flamm, Christoph;Fried, Claudia;Hackermüller, Jörg;Hertel, Jana;Lindemeyer, Manja;Missal, Kristin;Tanzer, Andrea;Washietl, Stefan;Korbel, Jan;Emanuelsson, Olof;Pedersen, Jakob S.;Holroyd, Nancy;Taylor, Ruth;Swarbreck, David;Matthews, Nicholas;Dickson, Mark C.;Thomas, Daryl J.;Weirauch, Matthew T.;Gilbert, James;Drenkow, Jorg;Bell, Ian;Zhao, Xiaodong;Srinivasan, K. G.;Sung, Wing Kin;Ooi, Hong Sain;Chiu, Kuo Ping;Foissac, Sylvain;Alioto, Tyler;Brent, Michael;Pachter, Lior;Tress, Michael L.;Valencia, Alfonso;Choo, Siew Woh;Choo, Chiou Yu;Ucla, Catherine;Manzano, Caroline;Wyss, Carine;Cheung, Evelyn;Clark, Taane G.;Brown, James B.;Ganesh, Madhavan;Patel, Sandeep;Tammana, Hari;Chrast, Jacqueline;Henrichsen, Charlotte N.;Kai, Chikatoshi;Kawai, Jun;Nagalakshmi, Ugrappa;Wu, Jiaqian;Lian, Zheng;Lian, Jin;Newburger, Peter;Zhang, Xueqing;Bickel, Peter;Mattick, John S.;Carninci, Piero;Hayashizaki, Yoshihide;Weissman, Sherman;Hubbard, Tim;Myers, Richard M.;Rogers, Jane;Stadler, Peter F.;Lowe, Todd M.;Wei, Chia Lin;Ruan, Yijun;Struhl, Kevin;Gerstein, Mark;Antonarakis, Stylianos E.;Fu, Yutao;Green, Eric D.;Karaöz, Ulaş;Siepel, Adam;Taylor, James;Liefer, Laura A.;Wetterstrand, Kris A.;Good, Peter J.;Feingold, Elise A.;Guyer, Mark S.;Cooper, Gregory M.;Asimenos, George;Dewey, Colin N.;Hou, Minmei;Nikolaev, Sergey;Montoya-Burgos, Juan I.;Löytynoja, Ari;Whelan, Simon;Pardi, Fabio;Massingham, Tim;Huang, Haiyan;Zhang, Nancy R.;Holmes, Ian;Mullikin, James C.;Ureta-Vidal, Abel;Paten, Benedict;Seringhaus, Michael;Church, Deanna;Rosenbloom, Kate;Kent, W. James;Stone, Eric A.;Batzoglou, Serafim;Goldman, Nick;Hardison, Ross C.;Haussler, David;Miller, Webb;Sidow, Arend;Trinklein, Nathan D.;Zhang, Zhengdong D.;Barrera, Leah;Stuart, Rhona;King, David C.;Ameur, Adam;Enroth, Stefan;Bieda, Mark C.;Kim, Jonghwan;Bhinge, Akshay A.;Jiang, Nan;Liu, Jun;Yao, Fei;Vega, Vinsensius B.;Lee, Charlie W H;Ng, Patrick;Yang, Annie;Moqtaderi, Zarmik;Zhu, Zhou;Xu, Xiaoqin;Squazzo, Sharon;Oberley, Matthew J.;Inman, David;Singer, Michael A.;Richmond, Todd A.;Munn, Kyle J.;Rada-Iglesias, Alvaro;Wallerman, Ola;Komorowski, Jan;Fowler, Joanna C.;Couttet, Phillippe;Bruce, Alexander W.;Dovey, Oliver M.;Ellis, Peter D.;Langford, Cordelia F.;Nix, David A.;Euskirchen, Ghia;Hartman, Stephen;Urban, Alexander E.;Kraus, Peter;Van Calcar, Sara;Heintzman, Nate;Hoon Kim, Tae;Wang, Kun;Qu, Chunxu;Hon, Gary;Luna, Rosa;Glass, Christopher K.;Rosenfeld, M. Geoff;Aldred, Shelley Force;Cooper, Sara J.;Halees, Anason;Lin, Jane M.;Shulha, Hennady P.;Zhang, Xiaoling;Xu, Mousheng;Haidar, Jaafar N S;Yu, Yong;Iyer, Vishwanath R.;Green, Roland D.;Wadelius, Claes;Farnham, Peggy J.;Ren, Bing;Harte, Rachel A.;Hinrichs, Angie S.;Trumbower, Heather;Clawson, Hiram;Hillman-Jackson, Jennifer;Zweig, Ann S.;Smith, Kayla;Thakkapallayil, Archana;Barber, Galt;Kuhn, Robert M.;Karolchik, Donna;Armengol, Lluis;Bird, Christine P.;De Bakker, Paul I W;Kern, Andrew D.;Lopez-Bigas, Nuria;Martin, Joel D.;Stranger, Barbara E.;Woodroffe, Abigail;Davydov, Eugene;Dimas, Antigone;Eyras, Eduardo;Hallgrímsdóttir, Ingileif B.;Huppert, Julian;Zody, Michael C.;Abecasis, Gonçalo R.;Estivill, Xavier;Bouffard, Gerard G.;Guan, Xiaobin;Hansen, Nancy F.;Idol, Jacquelyn R.;Maduro, Valerie V B;Maskeri, Baishali;McDowell, Jennifer C.;Park, Morgan;Thomas, Pamela J.;Young, Alice C.;Blakesley, Robert W.;Muzny, Donna M.;Sodergren, Erica;Wheeler, David A.;Worley, Kim C.;Jiang, Huaiyang;Weinstock, George M.;Gibbs, Richard A.;Graves, Tina;Fulton, Robert;Mardis, Elaine R.;Wilson, Richard K.;Clamp, Michele;Cuff, James;Gnerre, Sante;Jaffe, David B.;Chang, Jean L.;Lindblad-Toh, Kerstin;Lander, Eric S.;Koriabine, Maxim;Nefedov, Mikhail;Osoegawa, Kazutoyo;Yoshinaga, Yuko;Zhu, Baoli;De Jong, Pieter J.
We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project. These data have been further integrated and augmented by a nu...
Structural characteristics are essential for the functioning of many noncoding RNAs and cis-regulatory elements of mRNAs. SNPs may disrupt these structures, interfere with their molecular function, and hence cause a phenotypic effect. RNA folding alg...
Structural characteristics are essential for the functioning of many noncoding RNAs and cis-regulatory elements of mRNAs. SNPs may disrupt these structures, interfere with their molecular function, and hence cause a phenotypic effect. RNA folding alg...