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Title
BACKGROUND: Despite increasing numbers of human immunodeficiency virus (HIV)–infected South Africans receiving antiretroviral therapy (ART), tuberculosis (TB) remains the leading cause of mortality. Approximately 25% of patients treated for TB have m...
Cryptococcal meningitis accounts for 15% of all HIV-related deaths [1]. The overall number of cryptococcal meningitis cases has remained relatively stable in many low-to-middle income countries (LMICs) despite increasing roll-out of antiretroviral th...
Background The clinical and epidemiological significance of HIV-associated Mycobacterium tuberculosis bloodstream infection (BSI) is incompletely understood. We hypothesised that M tuberculosis BSI prevalence has been underestimated, that it independ...
Background Most tuberculosis-related deaths in people with HIV could be prevented with earlier diagnosis and treatment. The only commercially available tuberculosis point-of-care test (Alere Determine TB LAM Ag [AlereLAM]) has suboptimal sensitivity,...
Background In high-burden settings, case fatality rates are reported to be between 11% and 32% in hospitalized patients with HIV-associated tuberculosis, yet the underlying causes of mortality remain poorly characterized. Understanding causes of mort...
Brown, Gordon D;Meintjes, Graeme;Kolls, Jay K;Gray, Clive;Horsnell, William;Working Group from the EMBO-AIDS Related Mycoses Workshop,;Achan, Beatrice;Alber, Gottfried;Aloisi, Maria;Armstrong-James, Darius;Beale, Mathew;Bicanic, Tihana;Black, John;Bohjanen, Paul;Botes, Angela;Boulware, David R;Brown, Gordon;Bunjun, Rubina;Carr, William;Casadevall, Arturo;Chang, Christina;Chivero, Ernest;Corcoran, Craig;Cross, Anna;Dawood, Halima;Day, Jeremy;De Bernardis, Flavia;De Jager, Veronique;De Repentigny, Louis;Denning, David;Eschke, Maria;Finkelman, Malcolm;Govender, Nelesh;Gow, Neil;Graham, Lisa;Gryschek, Ronaldo;Hammond-Aryee, Kenneth;Harrison, Tom;Heard, Neil;Hill, Melanie;Hoving, J Claire;Janoff, Edward;Jarvis, Joseph;Kayuni, Sekeleghe;King, Karin;Kolls, Jay;Kullberg, Bart-Jan;Lalloo, David G;Letang, Emilio;Levitz, Stuart;Limper, Andrew;Longley, Nicky;Machiridza, Tendai Rodney;Mahabeer, Yesholata;Martinsons, Neil;Meiring, Susan;Meya, David;Miller, Robert;Molloy, Sile;Morris, Lynn;Mukaremera, Liliane;Musubire, Abdu K;Muzoora, Conrad;Nair, Amy;Nakiwala Kimbowa, Justine;Netea, Mihai;Nielsen, Kirsten;O'hern, Jennifer;Okurut, Samuel;Parker, Arifa;Patterson, Tom;Pennap, Grace;Perfect, John;Prinsloo, Chrisna;Rhein, Joshua;Rolfes, Melissa A;Samuel, Catherine;Schutz, Charlotte;Scriven, James;Sebolai, Olihile M;Sojane, Katlego;Sriruttan, Charlotte;Stead, David;Steyn, Annica;Thawer, Narjis K;Thienemann, Friedrich;Von Hohenberg, Maximilian;Vreulink, Jo-marie;Wessels, Jeannette;Wood, Kathryn;Yang, Yun-liang
The contribution of fungal infections to the morbidity and mortality of HIV-infected individuals is largely unrecognized. A recent meeting highlighted several priorities that need to be urgently addressed, including improved epidemiological surveilla...