van Houte, S;Ekroth, AKE;Broniewski, JM;Chabas, H;Ashby, B;Bondy-Denomy, J;Gandon, S;Boots, M;Paterson, S;Buckling, AJ;Westra, ER Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity1,2. This frequently results in high within-population spacer diversity3,4,5,6, ...
van Houte, S;Ekroth, AKE;Broniewski, JM;Chabas, H;Ashby, B;Bondy-Denomy, J;Gandon, S;Boots, M;Paterson, S;Buckling, AJ;Westra, ER Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity1,2. This frequently results in high within-population spacer diversity3,4,5,6, ...
Local adaptation of a species can affect community composition, yet the importance of local adaptation compared with species presence per se is unknown. Here we determine how a compost bacterial community exposed to elevated temperature changes over ...
King, KC;Brockhurst, MA;Vasieva, O;Paterson, S;Betts, A;Ford, SA;Frost, CL;Horsburgh, MJ;Haldenby, S;Hurst, GDD Microbes can defend their host against virulent infections, but direct evidence for the adaptive origin of microbe-mediated protection is lacking. Using experimental evolution of a novel, tripartite interaction, we demonstrate that mildly pathogenic ...
van Houte, S;Ekroth, AKE;Broniewski, JM;Chabas, H;Ashby, B;Bondy-Denomy, J;Gandon, S;Boots, M;Paterson, S;Buckling, AJ;Westra, ER Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity1,2. This frequently results in high within-population spacer diversity3,4,5,6, ...
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Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived sequences are more common in pathogenic than nonpathogenic taxa and are associated with changes in pathogen virulence. High abundance and mobilization of temperate p...
van Houte, S;Ekroth, AKE;Broniewski, JM;Chabas, H;Ashby, B;Bondy-Denomy, J;Gandon, S;Boots, M;Paterson, S;Buckling, AJ;Westra, ER Prokaryotic CRISPR-Cas adaptive immune systems insert spacers derived from viruses and other parasitic DNA elements into CRISPR loci to provide sequence-specific immunity1,2. This frequently results in high within-population spacer diversity3,4,5,6, ...
