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Parameters describing dynamic cerebral autoregulation (DCA) have limited reproducibility. In an international, multi-center study, we evaluated the influence of multiple analytical methods on the reproducibility of DCA. Fourteen participating centers...
10.1182/blood-2010-06-291641
Lango Allen, H;Estrada, K;Lettre, G;Berndt, SI;Weedon, MN;Rivadeneira, F;Willer, CJ;Jackson, AU;Vedantam, S;Raychaudhuri, S;Ferreira, T;Wood, AR;Weyant, RJ;Segrè, AV;Speliotes, EK;Wheeler, E;Soranzo, N;Park, JH;Yang, J;Gudbjartsson, D;Heard-Costa, NL;Randall, JC;Qi, L;Vernon Smith, A;Mägi, R;Pastinen, T;Liang, L;Heid, IM;Luan, J;Thorleifsson, G;Winkler, TW;Goddard, ME;Sin Lo, K;Palmer, C;Workalemahu, T;Aulchenko, YS;Johansson, A;Zillikens, MC;Feitosa, MF;Esko, T;Johnson, T;Ketkar, S;Kraft, P;Mangino, M;Prokopenko, I;Absher, D;Albrecht, E;Ernst, F;Glazer, NL;Hayward, C;Hottenga, JJ;Jacobs, KB;Knowles, JW;Kutalik, Z;Monda, KL;Polasek, O;Preuss, M;Rayner, NW;Robertson, NR;Steinthorsdottir, V;Tyrer, JP;Voight, BF;Wiklund, F;Xu, J;Zhao, JH;Nyholt, DR;Pellikka, N;Perola, M;Perry, JR;Surakka, I;Tammesoo, ML;Altmaier, EL;Amin, N;Aspelund, T;Bhangale, T;Boucher, G;Chasman, DI;Chen, C;Coin, L;Cooper, MN;Dixon, AL;Gibson, Q;Grundberg, E;Hao, K;Juhani Junttila, M;Kaplan, LM;Kettunen, J;König, IR;Kwan, T;Lawrence, RW;Levinson, DF;Lorentzon, M;McKnight, B;Morris, AP;Müller, M;Suh Ngwa, J;Purcell, S;Rafelt, S;Salem, RM;Salvi, E;Sanna, S;Shi, J;Sovio, U;Thompson, JR;Turchin, MC;Vandenput, L;Verlaan, DJ;Vitart, V;White, CC;Ziegler, A;Almgren, P;Balmforth, AJ;Campbell, H;Citterio, L;De Grandi, A;Dominiczak, A;Duan, J;Elliott, P;Elosua, R;Eriksson, JG;Freimer, NB;Geus, EJ;Glorioso, N;Haiqing, S;Hartikainen, AL;Havulinna, AS;Hicks, AA;Hui, J;Igl, W;Illig, T;Jula, A;Kajantie, E;Kilpeläinen, TO;Koiranen, M;Kolcic, I;Koskinen, S;Kovacs, P;Laitinen, J;Liu, J;Lokki, ML;Marusic, A;Maschio, A;Meitinger, T;Mulas, A;Paré, G;Parker, AN;Peden, JF;Petersmann, A;Pichler, I;Pietiläinen, KH;Pouta, A;Ridderstråle, M;Rotter, JI;Sambrook, JG;Sanders, AR;Schmidt, CO;Sinisalo, J;Smit, JH;Stringham, HM;Bragi Walters, G;Widen, E;Wild, SH;Willemsen, G;Zagato, L;Zgaga, L;Zitting, P;Alavere, H;Farrall, M;McArdle, WL;Nelis, M;Peters, MJ;Ripatti, S;van Meurs, JB;Aben, KK;Ardlie, KG;Beckmann, JS;Beilby, JP;Bergman, RN;Bergmann, S;Collins, FS;Cusi, D;den Heijer, M;Eiriksdottir, G;Gejman, PV;Hall, AS;Hamsten, A;Huikuri, HV;Iribarren, C;Kähönen, M;Kaprio, J;Kathiresan, S;Kiemeney, L;Kocher, T;Launer, LJ;Lehtimäki, T;Melander, O;Mosley, TH;Musk, AW;Nieminen, MS;O'Donnell, CJ;Ohlsson, C;Oostra, B;Palmer, LJ;Raitakari, O;Ridker, PM;Rioux, JD;Rissanen, A;Rivolta, C;Schunkert, H;Shuldiner, AR;Siscovick, DS;Stumvoll, M;Tönjes, A;Tuomilehto, J;van Ommen, GJ;Viikari, J;Heath, AC;Martin, NG;Montgomery, GW;Province, MA;Kayser, M;Arnold, AM;Atwood, LD;Boerwinkle, E;Chanock, SJ;Deloukas, P;Gieger, C;Grönberg, H;Hall, P;Hattersley, AT;Hengstenberg, C;Hoffman, W;Lathrop, GM;Salomaa, V;Schreiber, S;Uda, M;Waterworth, D;Wright, AF;Assimes, TL;Barroso, I;Hofman, A;Mohlke, KL;Boomsma, DI;Caulfield, MJ;Cupples, LA;Erdmann, J;Fox, CS;Gudnason, V;Gyllensten, U;Harris, TB;Hayes, RB;Jarvelin, MR;Mooser, V;Munroe, PB;Ouwehand, WH;Penninx, BW;Pramstaller, PP;Quertermous, T;Rudan, I;Samani, NJ;Spector, TD;Völzke, H;Watkins, H;Wilson, JF;Groop, LC;Haritunians, T;Hu, FB;Kaplan, RC;Metspalu, A;North, KE;Schlessinger, D;Wareham, NJ;Hunter, DJ;O'Connell, JR;Strachan, DP;Wichmann, HE;Borecki, IB;van Duijn, CM;Schadt, EE;Thorsteinsdottir, U;Peltonen, L;Uitterlinden, AG;Visscher, PM;Chatterjee, N;Loos, RJ;Boehnke, M;McCarthy, MI;Ingelsson, E;Lindgren, CM;Abecasis, GR;Stefansson, K;Frayling, TM;Hirschhorn, JN
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human trai...
M. Guerra acknowledges the support of the FCT, under Contract No. SFRH/BPD/92455/2013. This work was supported in part by the research center Grants No. UID/FIS/04559/2013 to LIBPhys-UNL, and No. UID/MULTI/04046/2013 to BioISI, from the FCT/MCTES/PID...
The understanding of the relationship between structure and properties of thin coatings is one of the key requirements for their further improvement. Especially for metastable TiAlN, commonly used as a protective coating for cutting applications, det...
Lango Allen, H;Estrada, K;Lettre, G;Berndt, SI;Weedon, MN;Rivadeneira, F;Willer, CJ;Jackson, AU;Vedantam, S;Raychaudhuri, S;Ferreira, T;Wood, AR;Weyant, RJ;Segrè, AV;Speliotes, EK;Wheeler, E;Soranzo, N;Park, JH;Yang, J;Gudbjartsson, D;Heard-Costa, NL;Randall, JC;Qi, L;Vernon Smith, A;Mägi, R;Pastinen, T;Liang, L;Heid, IM;Luan, J;Thorleifsson, G;Winkler, TW;Goddard, ME;Sin Lo, K;Palmer, C;Workalemahu, T;Aulchenko, YS;Johansson, A;Zillikens, MC;Feitosa, MF;Esko, T;Johnson, T;Ketkar, S;Kraft, P;Mangino, M;Prokopenko, I;Absher, D;Albrecht, E;Ernst, F;Glazer, NL;Hayward, C;Hottenga, JJ;Jacobs, KB;Knowles, JW;Kutalik, Z;Monda, KL;Polasek, O;Preuss, M;Rayner, NW;Robertson, NR;Steinthorsdottir, V;Tyrer, JP;Voight, BF;Wiklund, F;Xu, J;Zhao, JH;Nyholt, DR;Pellikka, N;Perola, M;Perry, JR;Surakka, I;Tammesoo, ML;Altmaier, EL;Amin, N;Aspelund, T;Bhangale, T;Boucher, G;Chasman, DI;Chen, C;Coin, L;Cooper, MN;Dixon, AL;Gibson, Q;Grundberg, E;Hao, K;Juhani Junttila, M;Kaplan, LM;Kettunen, J;König, IR;Kwan, T;Lawrence, RW;Levinson, DF;Lorentzon, M;McKnight, B;Morris, AP;Müller, M;Suh Ngwa, J;Purcell, S;Rafelt, S;Salem, RM;Salvi, E;Sanna, S;Shi, J;Sovio, U;Thompson, JR;Turchin, MC;Vandenput, L;Verlaan, DJ;Vitart, V;White, CC;Ziegler, A;Almgren, P;Balmforth, AJ;Campbell, H;Citterio, L;De Grandi, A;Dominiczak, A;Duan, J;Elliott, P;Elosua, R;Eriksson, JG;Freimer, NB;Geus, EJ;Glorioso, N;Haiqing, S;Hartikainen, AL;Havulinna, AS;Hicks, AA;Hui, J;Igl, W;Illig, T;Jula, A;Kajantie, E;Kilpeläinen, TO;Koiranen, M;Kolcic, I;Koskinen, S;Kovacs, P;Laitinen, J;Liu, J;Lokki, ML;Marusic, A;Maschio, A;Meitinger, T;Mulas, A;Paré, G;Parker, AN;Peden, JF;Petersmann, A;Pichler, I;Pietiläinen, KH;Pouta, A;Ridderstråle, M;Rotter, JI;Sambrook, JG;Sanders, AR;Schmidt, CO;Sinisalo, J;Smit, JH;Stringham, HM;Bragi Walters, G;Widen, E;Wild, SH;Willemsen, G;Zagato, L;Zgaga, L;Zitting, P;Alavere, H;Farrall, M;McArdle, WL;Nelis, M;Peters, MJ;Ripatti, S;van Meurs, JB;Aben, KK;Ardlie, KG;Beckmann, JS;Beilby, JP;Bergman, RN;Bergmann, S;Collins, FS;Cusi, D;den Heijer, M;Eiriksdottir, G;Gejman, PV;Hall, AS;Hamsten, A;Huikuri, HV;Iribarren, C;Kähönen, M;Kaprio, J;Kathiresan, S;Kiemeney, L;Kocher, T;Launer, LJ;Lehtimäki, T;Melander, O;Mosley, TH;Musk, AW;Nieminen, MS;O'Donnell, CJ;Ohlsson, C;Oostra, B;Palmer, LJ;Raitakari, O;Ridker, PM;Rioux, JD;Rissanen, A;Rivolta, C;Schunkert, H;Shuldiner, AR;Siscovick, DS;Stumvoll, M;Tönjes, A;Tuomilehto, J;van Ommen, GJ;Viikari, J;Heath, AC;Martin, NG;Montgomery, GW;Province, MA;Kayser, M;Arnold, AM;Atwood, LD;Boerwinkle, E;Chanock, SJ;Deloukas, P;Gieger, C;Grönberg, H;Hall, P;Hattersley, AT;Hengstenberg, C;Hoffman, W;Lathrop, GM;Salomaa, V;Schreiber, S;Uda, M;Waterworth, D;Wright, AF;Assimes, TL;Barroso, I;Hofman, A;Mohlke, KL;Boomsma, DI;Caulfield, MJ;Cupples, LA;Erdmann, J;Fox, CS;Gudnason, V;Gyllensten, U;Harris, TB;Hayes, RB;Jarvelin, MR;Mooser, V;Munroe, PB;Ouwehand, WH;Penninx, BW;Pramstaller, PP;Quertermous, T;Rudan, I;Samani, NJ;Spector, TD;Völzke, H;Watkins, H;Wilson, JF;Groop, LC;Haritunians, T;Hu, FB;Kaplan, RC;Metspalu, A;North, KE;Schlessinger, D;Wareham, NJ;Hunter, DJ;O'Connell, JR;Strachan, DP;Wichmann, HE;Borecki, IB;van Duijn, CM;Schadt, EE;Thorsteinsdottir, U;Peltonen, L;Uitterlinden, AG;Visscher, PM;Chatterjee, N;Loos, RJ;Boehnke, M;McCarthy, MI;Ingelsson, E;Lindgren, CM;Abecasis, GR;Stefansson, K;Frayling, TM;Hirschhorn, JN
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human trai...
Parameters describing dynamic cerebral autoregulation (DCA) have limited reproducibility. In an international, multi-center study, we evaluated the influence of multiple analytical methods on the reproducibility of DCA. Fourteen participating centers...