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Wood, Andrew R.;Esko, Tonu;Yang, Jian;Vedantam, Sailaja;Pers, Tune H.;Gustafsson, Stefan;Chun, Audrey Y.;Estrada, Karol;Luan, Jian'An;Kutalik, Zoltan;Amin, Najaf;Buchkovich, Martin L.;Croteau-Chonka, Damien C.;Day, Felix R.;Duan, Yanan;Fall, Tove;Fehrmann, Rudolf;Ferreira, Teresa;Jackson, Anne U.;Karjalainen, Juha;Lo, Ken Sin;Locke, Adam E.;Maegi, Reedik;Mihailov, Evelin;Porcu, Eleonora;Randall, Joshua C.;Scherag, Andre;Vinkhuyzen, Anna A. E.;Westra, Harm-Jan;Winkler, Thomas W.;Workalemahu, Tsegaselassie;Zhao, Jing Hua;Absher, Devin;Albrecht, Eva;Anderson, Denise;Baron, Jeffrey;Beekman, Marian;Demirkan, Ayse;Ehret, Georg B.;Feenstra, Bjarke;Feitosa, Mary F.;Fischer, Krista;Fraser, Ross M.;Goel, Anuj;Gong, Jian;Justice, Anne E.;Kanoni, Stavroula;Kleber, Marcus E.;Kristiansson, Kati;Lim, Unhee;Lotay, Vaneet;Lui, Julian C.;Mangino, Massimo;Leach, Irene Mateo;Medina-Gomez, Carolina;Nalls, Michael A.;Nyholt, Dale R.;Palmer, Cameron D.;Pasko, Dorota;Pechlivanis, Sonali;Prokopenko, Inga;Ried, Janina S.;Ripke, Stephan;Shungin, Dmitry;Stancakova, Alena;Strawbridge, Rona J.;Sung, Yun Ju;Tanaka, Toshiko;Teumer, Alexander;Trompet, Stella;Van Der Laan, Sander W.;Van Setten, Jessica;Van Vliet-Ostaptchouk, Jana V.;Wang, Zhaoming;Yengo, Loic;Zhang, Weihua;Afzal, Uzma;Arnloev, Johan;Arscott, Gillian M.;Bandinelli, Stefania;Barrett, Amy;Bellis, Claire;Bennett, Amanda J.;Berne, Christian;Blueher, Matthias;Bolton, Jennifer L.;Boettcher, Yvonne;Boyd, Heather A.;Bruinenberg, Marcel;Buckley, Brendan M.;Buyske, Steven;Caspersen, Ida H.;Chines, Peter S.;Clarke, Robert;Claudi-Boehm, Simone;Cooper, Matthew;Daw, E. Warwick;De Jong, Pim A.;Deelen, Joris;Delgado, Graciela;Denny, Josh C.;Dhonukshe-Rutten, Rosalie;Dimitriou, Maria;Doney, Alex S. F.;Doerr, Marcus;Eklund, Niina;Eury, Elodie;Folkersen, Lasse;Garcia, Melissa E.;Geller, Frank;Giedraitis, Vilmantas;Go, Alan S.;Grallert, Harald;Grammer, Tanja B.;Graessler, Juergen;Groenberg, Henrik;De Groot, Lisette C. P. G. M.;Groves, Christopher J.;Haessler, Jeffrey;Hall, Per;Haller, Toomas;Hallmans, Goran;Hannemann, Anke;Hartman, Catharina A.;Hassinen, Maija;Hayward, Caroline;Heard-Costa, Nancy L.;Helmer, Quinta;Hemani, Gibran;Henders, Anjali K.;Hillege, Hans L.;Hlatky, Mark A.;Hoffmann, Wolfgang;Hoffmann, Per;Holmen, Oddgeir;Houwing-Duistermaat, Jeanine J.;Illig, Thomas;Isaacs, Aaron;James, Alan L.;Jeff, Janina;Johansen, Bent;Johansson, Asa;Jolley, Jennifer;Juliusdottir, Thorhildur;Junttila, Juhani;Kho, Abel N.;Kinnunen, Leena;Klopp, Norman;Kocher, Thomas;Kratzer, Wolfgang;Lichtner, Peter;Lind, Lars;Lindstroem, Jaana;Lobbens, Stephane;Lorentzon, Mattias;Lu, Yingchang;Lyssenko, Valeriya;Magnusson, Patrik K. E.;Mahajan, Anubha;Maillard, Marc;Mcardle, Wendy L.;Mckenzie, Colin A.;Mclachlan, Stela;Mclaren, Paul J.;Menni, Cristina;Merger, Sigrun;Milani, Lili;Moayyeri, Alireza;Monda, Keri L.;Morken, Mario A.;Mueller, Gabriele;Mueller-Nurasyid, Martina;Musk, Arthur W.;Narisu, Narisu;Nauck, Matthias;Nolte, Ilja M.;Noethen, Markus M.;Oozageer, Laticia;Pilz, Stefan;Rayner, Nigel W.;Renstrom, Frida;Robertson, Neil R.;Rose, Lynda M.;Roussel, Ronan;Sanna, Serena;Scharnagl, Hubert;Scholtens, Salome;Schumacher, Fredrick R.;Schunkert, Heribert;Scott, Robert A.;Sehmi, Joban;Seufferlein, Thomas;Shin, Jianxin;Silventoinen, Karri;Smit, Johannes H.;Smith, Albert Vernon;Smolonska, Joanna;Stanton, Alice V.;Stirrups, Kathleen;Stott, David J.;Stringham, Heather M.;Sundstrom, Johan;Swertz, Morris A.;Syvanen, Ann-Christine;Tayo, Bamidele O.;Thorleifsson, Gudmar;Tyrer, Jonathan P.;Van Dijk, Suzanne;Van Schoor, Natasja M.;Van Der Velde, Nathalie;Van Heemst, Diana;Van Oort, Floor V. A.;Vermeulen, Sita H.;Verweij, Niek;Vonk, Judith M.;Waite, Lindsay L.;Waldenberger, Melanie;Wennauer, Roman;Wilkens, Lynne R.;Willenborg, Christina;Wilsgaard, Tom;Wojczynski, Mary K.;Wong, Andrew;Wright, Alan F.;Zhang, Qunyuan;Arveiler, Dominique;Bakker, Stephan J. L.;Beilby, John;Bergman, Richard N.;Bergmann, Sven;Biffar, Reiner;Blangero, John;Boomsma, Dorret I.;Bornstein, Stefan R.;Bovet, Pascal;Brambilla, Paolo;Brown, Morris J.;Campbell, Harry;Caulfield, Mark J.;Chakravarti, Aravinda;Collins, Rory;Collins, Francis S.;Crawford, Dana C.;Cupples, L. Adrienne;Danesh, John;De Faire, Ulf;Den Ruijter, Hester M.;Erbel, Raimund;Erdmann, Jeanette;Eriksson, Johan G.;Farrall, Martin;Ferrannini, Ele;Ferrieres, Jean;Ford, Ian;Forouhi, Nita G.;Forrester, Terrence;Gansevoort, Ron T.;Gejman, Pablo V.;Gieger, Christian;Golay, Alain;Gottesman, Omri;Gudnason, Vilmundur;Gyllensten, Ulf;Haas, David W.;Hall, Alistair S.;Harris, Tamara B.;Hattersley, Andrew T.;Heath, Andrew C.;Hengstenberg, Christian;Hicks, Andrew A.;Hindorff, Lucia A.;Hingorani, Aroon D.;Hofman, Albert;Hovingh, G. Kees;Humphries, Steve E.;Hunt, Steven C.;Hypponen, Elina;Jacobs, Kevin B.;Jarvelin, Marjo-Riitta;Jousilahti, Pekka;Jula, Antti M.;Kaprio, Jaakko;Kastelein, John J. P.;Kayser, Manfred;Kee, Frank;Keinanen-Kiukaanniemi, Sirkka M.;Kiemeney, Lambertus A.;Kooner, Jaspal S.;Kooperberg, Charles;Koskinen, Seppo;Kovacs, Peter;Kraja, Aldi T.;Kumari, Meena;Kuusisto, Johanna;Lakka, Timo A.;Langenberg, Claudia;Le Marchand, Loic;Lehtimaki, Terho;Lupoli, Sara;Madden, Pamela A. F.;Mannisto, Satu;Manunta, Paolo;Marette, Andre;Matise, Tara C.;Mcknight, Barbara;Meitinger, Thomas;Moll, Frans L.;Montgomery, Grant W.;Morris, Andrew D.;Morris, Andrew P.;Murray, Jeffrey C.;Nelis, Mari;Ohlsson, Claes;Oldehinkel, Albertine J.;Ong, Ken K.;Ouwehand, Willem H.;Pasterkamp, Gerard;Peters, Annette;Pramstaller, Peter P.;Price, Jackie F.;Qi, Lu;Raitakari, Olli T.;Rankinen, Tuomo;Rao, D. C.;Rice, Treva K.;Ritchie, Marylyn;Rudan, Igor;Salomaa, Veikko;Samani, Nilesh J.;Saramies, Jouko;Sarzynski, Mark A.;Schwarz, Peter E. H.;Sebert, Sylvain;Sever, Peter;Shuldiner, Alan R.;Sinisalo, Juha;Steinthorsdottir, Valgerdur;Stolk, Ronald P.;Tardif, Jean-Claude;Toenjes, Anke;Tremblay, Angelo;Tremoli, Elena;Virtamo, Jarmo;Vohl, Marie-Claude;Amouyel, Philippe;Asselbergs, Folkert W.;Assimes, Themistocles L.;Bochud, Murielle;Boehm, Bernhard O.;Boerwinkle, Eric;Bottinger, Erwin P.;Bouchard, Claude;Cauchi, Stephane;Chambers, John C.;Chanock, Stephen J.;Cooper, Richard S.;De Bakker, Paul I. W.;Dedoussis, George;Ferrucci, Luigi;Franks, Paul W.;Froguel, Philippe;Groop, Leif C.;Haiman, Christopher A.;Hamsten, Anders;Hayes, M. Geoffrey;Hui, Jennie;Hunter, David J.;Hveem, Kristian;Jukema, J. Wouter;Kaplan, Robert C.;Kivimaki, Mika;Kuh, Diana;Laakso, Markku;Liu, Yongmei;Martin, Nicholas G.;Maerz, Winfried;Melbye, Mads;Moebus, Susanne;Munroe, Patricia B.;Njolstad, Inger;Oostra, Ben A.;Palmer, Colin N. A.;Pedersen, Nancy L.;Perola, Markus;Perusse, Louis;Peters, Ulrike;Powell, Joseph E.;Power, Chris;Quertermous, Thomas;Rauramaa, Rainer;Reinmaa, Eva;Ridker, Paul M.;Rivadeneira, Fernando;Rotter, Jerome I.;Saaristo, Timo E.;Saleheen, Danish;Schlessinger, David;Slagboom, P. Eline;Snieder, Harold;Spector, Tim D.;Strauch, Konstantin;Stumvoll, Michael;Tuomilehto, Jaakko;Uusitupa, Matti;Van Der Harst, Pim;Voelzke, Henry;Walker, Mark;Wareham, Nicholas J.;Watkins, Hugh;Wichmann, H-Erich;Wilson, James F.;Zanen, Pieter;Deloukas, Panos;Heid, Iris M.;Lindgren, Cecilia M.;Mohlke, Karen L.;Speliotes, Elizabeth K.;Thorsteinsdottir, Unnur;Barroso, Ines;Fox, Caroline S.;North, Kari E.;Strachan, David P.;Beckmann, Jacques S.;Berndt, Sonja I.;Boehnke, Michael;Borecki, Ingrid B.;Mccarthy, Mark I.;Metspalu, Andres;Stefansson, Kari;Uitterlinden, Andre G.;Van Duijn, Cornelia M.;Franke, Lude;Willer, Cristen J.;Price, Alkes L.;Lettre, Guillaume;Loos, Ruth J. F.;Weedon, Michael N.;Ingelsson, Erik;O'Connell, Jeffrey R.;Abecasis, Goncalo R.;Chasman, Daniel I.;Goddard, Michael E.;Visscher, Peter M.;Hirschhorn, Joel N.;Frayling, Timothy M.
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show t...
Aim: We investigated the long-term impact of adjunctive systemic antibiotics on periodontal disease progression. Periodontal therapy is frequently supplemented by systemic antibiotics, although its impact on the course of disease is still unclear. Ma...
Marouli, Eirini;Graff, Mariaelisa;Medina-Gomez, Carolina;Lo, Ken Sin;Wood, Andrew R.;Kjaer, Troels R.;Fine, Rebecca S.;Lu, Yingchang;Schurmann, Claudia;Highland, Heather M.;Rüeger, Sina;Thorleifsson, Gudmar;Justice, Anne E.;Lamparter, David;Stirrups, Kathleen E.;Turcot, Valérie;Young, Kristin L.;Winkler, Thomas W.;Esko, Tõnu;Karaderi, Tugce;Locke, Adam E.;Masca, Nicholas G.D.;Ng, Maggie C.Y.;Mudgal, Poorva;Rivas, Manuel A.;Vedantam, Sailaja;Mahajan, Anubha;Guo, Xiuqing;Abecasis, Goncalo;Aben, Katja K.;Adair, Linda S.;Alam, Dewan S.;Albrecht, Eva;Allin, Kristine H.;Allison, Matthew;Amouyel, Philippe;Appel, Emil V.;Arveiler, Dominique;Asselbergs, Folkert W.;Auer, Paul L.;Balkau, Beverley;Banas, Bernhard;Bang, Lia E.;Benn, Marianne;Bergmann, Sven;Bielak, Lawrence F.;Blüher, Matthias;Boeing, Heiner;Boerwinkle, Eric;Böger, Carsten A.;Bonnycastle, Lori L.;Bork-Jensen, Jette;Bots, Michiel L.;Bottinger, Erwin P.;Bowden, Donald W.;Brandslund, Ivan;Breen, Gerome;Brilliant, Murray H.;Broer, Linda;Burt, Amber A.;Butterworth, Adam S.;Carey, David J.;Caulfield, Mark J.;Chambers, John C.;Chasman, Daniel I.;Chen, Yii-Der Ida;Chowdhury, Rajiv;Christensen, Cramer;Chu, Audrey Y.;Cocca, Massimiliano;Collins, Francis S.;Cook, James P.;Corley, Janie;Galbany, Jordi Corominas;Cox, Amanda J.;Cuellar-Partida, Gabriel;Danesh, John;Davies, Gail;de Bakker, Paul I.W.;de Borst, Gert J.;de Denus, Simon;de Groot, Mark C.H.;de Mutsert, Renée;Deary, Ian J.;Dedoussis, George;Demerath, Ellen W;den Hollander, Anneke I.;Dennis, Joe G.;Di Angelantonio, Emanuele;Drenos, Fotios;Du, Mengmeng;Dunning, Alison M.;Easton, Douglas F.;Ebeling, Tapani;Edwards, Todd L.;Ellinor, Patrick T.;Elliott, Paul;Evangelou, Evangelos;Farmaki, Aliki-Eleni;Faul, Jessica D.;Feitosa, Mary F.;Feng, Shuang;Ferrannini, Ele;Ferrario, Marco M.;Ferrieres, Jean;Florez, Jose C.;Ford, Ian;Fornage, Myriam;Franks, Paul W.;Frikke-Schmidt, Ruth;Galesloot, Tessel E.;Gan, Wei;Gandin, Ilaria;Gasparini, Paolo;Giedraitis, Vilmantas;Giri, Ayush;Girotto, Giorgia;Gordon, Scott D.;Gordon-Larsen, Penny;Gorski, Mathias;Grarup, Niels;Grove, Megan L.;Gudnason, Vilmundur;Gustafsson, Stefan;Hansen, Torben;Harris, Kathleen Mullan;Harris, Tamara B.;Hattersley, Andrew T.;Hayward, Caroline;He, Liang;Heid, Iris M.;Heikkilä, Kauko;Helgeland, Øyvind;Hernesniemi, Jussi;Hewitt, Alex W.;Hocking, Lynne J.;Hollensted, Mette;Holmen, Oddgeir L.;Hovingh, G. Kees;Howson, Joanna M.M.;Hoyng, Carel B.;Huang, Paul L.;Hveem, Kristian;Ikram, M. Arfan;Ingelsson, Erik;Jackson, Anne U.;Jansson, Jan-Håkan;Jarvik, Gail P.;Jensen, Gorm B.;Jhun, Min A.;Jia, Yucheng;Jiang, Xuejuan;Johansson, Stefan;Jørgensen, Marit E.;Jørgensen, Torben;Jousilahti, Pekka;Jukema, J. Wouter;Kahali, Bratati;Kahn, René S.;Kähönen, Mika;Kamstrup, Pia R.;Kanoni, Stavroula;Kaprio, Jaakko;Karaleftheri, Maria;Kardia, Sharon L.R.;Karpe, Fredrik;Kee, Frank;Keeman, Renske;Kiemeney, Lambertus A.;Kitajima, Hidetoshi;Kluivers, Kirsten B.;Kocher, Thomas;Komulainen, Pirjo;Kontto, Jukka;Kooner, Jaspal S.;Kooperberg, Charles;Kovacs, Peter;Kriebel, Jennifer;Kuivaniemi, Helena;Küry, Sébastien;Kuusisto, Johanna;La Bianca, Martina;Laakso, Markku;Lakka, Timo A.;Lange, Ethan M.;Lange, Leslie A.;Langefeld, Carl D.;Langenberg, Claudia;Larson, Eric B.;Lee, I-Te;Lehtimäki, Terho;Lewis, Cora E.;Li, Huaixing;Li, Jin;Li-Gao, Ruifang;Lin, Honghuang;Lin, Li-An;Lin, Xu;Lind, Lars;Lindström, Jaana;Linneberg, Allan;Liu, Yeheng;Liu, Yongmei;Lophatananon, Artitaya;Luan, Jian'an;Lubitz, Steven A.;Lyytikäinen, Leo-Pekka;Mackey, David A.;Madden, Pamela A.F.;Manning, Alisa K;Männistö, Satu;Marenne, Gaëlle;Marten, Jonathan;Martin, Nicholas G.;Mazul, Angela L.;Meidtner, Karina;Metspalu, Andres;Mitchell, Paul;Mohlke, Karen L.;Mook-Kanamori, Dennis O.;Morgan, Anna;Morris, Andrew D.;Morris, Andrew P.;Müller-Nurasyid, Martina;Munroe, Patricia B.;Nalls, Mike A.;Nauck, Matthias;Nelson, Christopher P.;Neville, Matt;Nielsen, Sune F.;Nikus, Kjell;Njølstad, Pål R.;Nordestgaard, Børge G.;Ntalla, Ioanna;O'Connel, Jeffrey R.;Oksa, Heikki;Loohuis, Loes M Olde;Ophoff, Roel A.;Owen, Katharine R.;Packard, Chris J.;Padmanabhan, Sandosh;Palmer, Colin N.A.;Pasterkamp, Gerard;Patel, Aniruddh P.;Pattie, Alison;Pedersen, Oluf;Peissig, Peggy L.;Peloso, Gina M.;Pennell, Craig E.;Perola, Markus;Perry, James A.;Perry, John R.B.;Person, Thomas N.;Pirie, Ailith;Polasek, Ozren;Posthuma, Danielle;Raitakari, Olli T.;Rasheed, Asif;Rauramaa, Rainer;Reilly, Dermot F.;Reiner, Alex P.;Renström, Frida;Ridker, Paul M.;Rioux, John D.;Robertson, Neil;Robino, Antonietta;Rolandsson, Olov;Rudan, Igor;Ruth, Katherine S.;Saleheen, Danish;Salomaa, Veikko;Samani, Nilesh J.;Sandow, Kevin;Sapkota, Yadav;Sattar, Naveed;Schmidt, Marjanka K.;Schreiner, Pamela J.;Schulze, Matthias B.;Scott, Robert A.;Segura-Lepe, Marcelo P.;Shah, Svati;Sim, Xueling;Sivapalaratnam, Suthesh;Small, Kerrin S.;Smith, Albert Vernon;Smith, Jennifer A.;Southam, Lorraine;Spector, Timothy D.;Speliotes, Elizabeth K.;Starr, John M.;Steinthorsdottir, Valgerdur;Stringham, Heather M.;Stumvoll, Michael;Surendran, Praveen;'t Hart, Leen M.;Tansey, Katherine E.;Tardif, Jean-Claude;Taylor, Kent D.;Teumer, Alexander;Thompson, Deborah J.;Thorsteinsdottir, Unnur;Thuesen, Betina H.;Tönjes, Anke;Tromp, Gerard;Trompet, Stella;Tsafantakis, Emmanouil;Tuomilehto, Jaakko;Tybjaerg-Hansen, Anne;Tyrer, Jonathan P.;Uher, Rudolf;Uitterlinden, André G.;Ulivi, Sheila;van der Laan, Sander W.;Van Der Leij, Andries R.;van Duijn, Cornelia M.;van Schoor, Natasja M.;van Setten, Jessica;Varbo, Anette;Varga, Tibor V.;Varma, Rohit;Velez Edwards, Digna R.;Vermeulen, Sita H.;Vestergaard, Henrik;Vitart, Veronique;Vogt, Thomas F.;Vozzi, Diego;Walker, Mark;Wang, Feijie;Wang, Carol A.;Wang, Shuai;Wang, Yiqin;Wareham, Nicholas J.;Warren, Helen R.;Wessel, Jennifer;Willems, Sara M.;Wilson, James G.;Witte, Daniel R.;Woods, Michael O.;Wu, Ying;Yaghootkar, Hanieh;Yao, Jie;Yao, Pang;Yerges-Armstrong, Laura M.;Young, Robin;Zeggini, Eleftheria;Zhan, Xiaowei;Zhang, Weihua;Zhao, Jing Hua;Zhao, Wei;Zhao, Wei;Zheng, He;Zhou, Wei;Rotter, Jerome I.;Boehnke, Michael;Kathiresan, Sekar;McCarthy, Mark I.;Willer, Cristen J.;Stefansson, Kari;Borecki, Ingrid B.;Liu, Dajiang J.;North, Kari E.;Heard-Costa, Nancy L.;Pers, Tune H.;Lindgren, Cecilia M.;Oxvig, Claus;Kutalik, Zoltán;Rivadeneira, Fernando;Loos, Ruth J.F.;Frayling, Timothy M.;Hirschhorn, Joel N.;Deloukas, Panos;Lettre, Guillaume
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencie...
Aim: We investigated the long-term impact of adjunctive systemic antibiotics on periodontal disease progression. Periodontal therapy is frequently supplemented by systemic antibiotics, although its impact on the course of disease is still unclear. Ma...
Allen, Hana Lango;Estrada, Karol;Lettre, Guillaume;Berndt, Sonja I.;Weedon, Michael N.;Rivadeneira, Fernando;Willer, Cristen J.;Jackson, Anne U.;Vedantam, Sailaja;Raychaudhuri, Soumya;Ferreira, Teresa;Wood, Andrew R.;Weyant, Robert J.;Segre, Ayellet V.;Speliotes, Elizabeth K.;Wheeler, Eleanor;Soranzo, Nicole;Park, Ju-Hyun;Yang, Jian;Gudbjartsson, Daniel;Heard-Costa, Nancy L.;Randall, Joshua C.;Qi, Lu;Smith, Albert Vernon;Maegi, Reedik;Pastinen, Tomi;Liang, Liming;Heid, Iris M.;Luan, Jian'an;Thorleifsson, Gudmar;Winkler, Thomas W.;Goddard, Michael E.;Lo, Ken Sin;Palmer, Cameron;Workalemahu, Tsegaselassie;Aulchenko, Yurii S.;Johansson, Asa;Zillikens, M. Carola;Feitosa, Mary F.;Esko, Tonu;Johnson, Toby;Ketkar, Shamika;Kraft, Peter;Mangino, Massimo;Prokopenko, Inga;Absher, Devin;Albrecht, Eva;Ernst, Florian;Glazer, Nicole L.;Hayward, Caroline;Hottenga, Jouke-Jan;Jacobs, Kevin B.;Knowles, Joshua W.;Kutalik, Zoltan;Monda, Keri L.;Polasek, Ozren;Preuss, Michael;Rayner, Nigel W.;Robertson, Neil R.;Steinthorsdottir, Valgerdur;Tyrer, Jonathan P.;Voight, Benjamin F.;Wiklund, Fredrik;Xu, Jianfeng;Zhao, Jing Hua;Nyholt, Dale R.;Pellikka, Niina;Perola, Markus;Perry, John R. B.;Surakka, Ida;Tammesoo, Mari-Liis;Altmaier, Elizabeth L.;Amin, Najaf;Aspelund, Thor;Bhangale, Tushar;Boucher, Gabrielle;Chasman, Daniel I.;Chen, Constance;Coin, Lachlan;Cooper, Matthew N.;Dixon, Anna L.;Gibson, Quince;Grundberg, Elin;Hao, Ke;Junttila, M. Juhani;Kaplan, Lee M.;Kettunen, Johannes;Koenig, Inke R.;Kwan, Tony;Lawrence, Robert W.;Levinson, Douglas F.;Lorentzon, Mattias;McKnight, Barbara;Morris, Andrew P.;Mueller, Martina;Ngwa, Julius Suh;Purcell, Shaun;Rafelt, Suzanne;Salem, Rany M.;Salvi, Erika;Sanna, Serena;Shi, Jianxin;Sovio, Ulla;Thompson, John R.;Turchin, Michael C.;Vandenput, Liesbeth;Verlaan, Dominique J.;Vitart, Veronique;White, Charles C.;Ziegler, Andreas;Almgren, Peter;Balmforth, Anthony J.;Campbell, Harry;Citterio, Lorena;De Grandi, Alessandro;Dominiczak, Anna;Duan, Jubao;Elliott, Paul;Elosua, Roberto;Eriksson, Johan G.;Freimer, Nelson B.;Geus, Eco J. C.;Glorioso, Nicola;Haiqing, Shen;Hartikainen, Anna-Liisa;Havulinna, Aki S.;Hicks, Andrew A.;Hui, Jennie;Igl, Wilmar;Illig, Thomas;Jula, Antti;Kajantie, Eero;Kilpelaeinen, Tuomas O.;Koiranen, Markku;Kolcic, Ivana;Koskinen, Seppo;Kovacs, Peter;Laitinen, Jaana;Liu, Jianjun;Lokki, Marja-Liisa;Marusic, Ana;Maschio, Andrea;Meitinger, Thomas;Mulas, Antonella;Pare, Guillaume;Parker, Alex N.;Peden, John F.;Petersmann, Astrid;Pichler, Irene;Pietilainen, Kirsi H.;Pouta, Anneli;Riddertrale, Martin;Rotter, Jerome I.;Sambrook, Jennifer G.;Sanders, Alan R.;Schmidt, Carsten Oliver;Sinisalo, Juha;Smit, Jan H.;Stringham, Heather M.;Walters, G. Bragi;Widen, Elisabeth;Wild, Sarah H.;Willemsen, Gonneke;Zagato, Laura;Zgaga, Lina;Zitting, Paavo;Alavere, Helene;Farrall, Martin;McArdle, Wendy L.;Nelis, Mari;Peters, Marjolein J.;Ripatti, Samuli;vVan Meurs, Joyce B. J.;Aben, Katja K.;Ardlie, Kristin G.;Beckmann, Jacques S.;Beilby, John P.;Bergman, Richard N.;Bergmann, Sven;Collins, Francis S.;Cusi, Daniele;den Heijer, Martin;Eiriksdottir, Gudny;Gejman, Pablo V.;Hall, Alistair S.;Hamsten, Anders;Huikuri, Heikki V.;Iribarren, Carlos;Kahonen, Mika;Kaprio, Jaakko;Kathiresan, Sekar;Kiemeney, Lambertus;Kocher, Thomas;Launer, Lenore J.;Lehtimaki, Terho;Melander, Olle;Mosley, Tom H., Jr.;Musk, Arthur W.;Nieminen, Markku S.;O'Donnell, Christopher J.;Ohlsson, Claes;Oostra, Ben;Palmer, Lyle J.;Raitakari, Olli;Ridker, Paul M.;Rioux, John D.;Rissanen, Aila;Rivolta, Carlo;Schunkert, Heribert;Shuldiner, Alan R.;Siscovick, David S.;Stumvoll, Michael;Toenjes, Anke;Tuomilehto, Jaakko;van Ommen, Gert-Jan;Viikari, Jorma;Heath, Andrew C.;Martin, Nicholas G.;Montgomery, Grant W.;Province, Michael A.;Kayser, Manfred;Arnold, Alice M.;Atwood, Larry D.;Boerwinkle, Eric;Chanock, Stephen J.;Deloukas, Panos;Gieger, Christian;Gronberg, Henrik;Hall, Per;Hattersley, Andrew T.;Hengstenberg, Christian;Hoffman, Wolfgang;Lathrop, G. Mark;Salomaa, Veikko;Schreiber, Stefan;Uda, Manuela;Waterworth, Dawn;Wright, Alan F.;Assimes, Themistocles L.;Barroso, Ines;Hofman, Albert;Mohlke, Karen L.;Boomsma, Dorret I.;Caulfield, Mark J.;Cupples, L. Adrienne;Erdmann, Jeanette;Fox, Caroline S.;Gudnason, Vilmundur;Gyllensten, Ulf;Harris, Tamara B.;Hayes, Richard B.;Jarvelin, Marjo-Ritta;Mooser, Vincent;Munroe, Patricia B.;Ouwehand, Willem H.;Penninx, Brenda W.;Pramstaller, Peter P.;Quertermous, Thomas;Rudan, Igor;Samani, Nilesh J.;Spector, Timothy D.;Voelzke, Henry;Watkins, Hugh;Wilson, James F.;Groop, Leif;Haritunians, Talin;Hu, Frank B.;Kaplan, Robert C.;Metspalu, Andres;North, Kari E.;Schlessinger, David;Wareham, Nicholas J.;Hunter, David J.;O'Connell, Jeffrey R.;Strachan, David P.;Schadt, H. -Erich;Thorsteinsdottir, Unnur;Peltonen, Leena;Uitterlinden, Andre G.;Visscher, Peter M.;Chatterjee, Nilanjan;Loos, Ruth J. F.;Boehnke, Michael;McCarthy, Mark I.;Ingelsson, Erik;Lindgren, Cecilia M.;Abecasis, Goncalo R.;Stefansson, Kari;Frayling, Timothy M.;Hirschhorn, Joel N.
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human trai...
The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI).
Marouli, Eirini;Graff, Mariaelisa;Medina-Gomez, Carolina;Lo, Ken Sin;Wood, Andrew R;Kjaer, Troels R.;Fine, Rebecca S.;Lu, Yingchang;Schurmann, Claudia;Highland, Heather M;Rüeger, Sina;Thorleifsson, Gudmar;Justice, Anne E;Lamparter, David;Stirrups, Kathleen E.;Turcot, Valérie;Young, Kristin L.;Winkler, Thomas W;Esko, Tõnu;Karaderi, Tugce;Locke, Adam E.;Masca, Nicholas G D;Ng, Maggie C. Y.;Mudgal, Poorva;Rivas, Manuel A;Vedantam, Sailaja;Mahajan, Anubha;Guo, Xiuqing;Abecasis, Goncalo;Aben, Katja K;Adair, Linda S.;Alam, Dewan S.;Albrecht, Eva;Allin, Kristine H.;Allison, Matthew;Amouyel, Philippe;Appel, Emil V.;Arveiler, Dominique;Asselbergs, Folkert W;Auer, Paul L.;Balkau, Beverley;Banas, Bernhard;Bang, Lia E;Benn, Marianne;Bergmann, Sven;Bielak, Lawrence F.;Blüher, Matthias;Boeing, Heiner;Boerwinkle, Eric;Böger, Carsten A;Bonnycastle, Lori;Bork-Jensen, Jette;Bots, Michiel L.;Bottinger, Erwin P;Bowden, Donald W.;Brandslund, Ivan;Breen, Gerome;Brilliant, Murray H.;Broer, Linda;Burt, Amber;Butterworth, Adam S.;Carey, David J.;Caulfield, Mark J.;Chambers, John C;Chasman, Daniel I.;Chen, Yii-Der Ida;Chowdhury, Rajiv;Christensen, Cramer;Chu, Audrey Y.;Cocca, Massimiliano;Collins, Francis S.;Cook, James P.;Corley, Janie;Galbany, Jordi Corominas;Cox, Amanda J.;Cuellar-Partida, Gabriel;Danesh, John;Davies, Gail;De Bakker, Paul I.W.;de Borst, Gert J.;de Denus, Simon;de Groot, Mark C. H.;De Mutsert, Renée;Deary, Ian J;Dedoussis, George;Demerath, Ellen W.;den Hollander, Anneke I.;Dennis, Joe G.;Di Angelantonio, Emanuele;Drenos, Fotios;Du, Mengmeng;Dunning, Alison M.;Easton, Douglas F;Ebeling, Tapani;Edwards, Todd L;Ellinor, Patrick T;Elliott, Paul;Evangelou, Evangelos;Farmaki, Aliki-Eleni;Faul, Jessica D;Feitosa, Mary F;Feng, Shuang;Ferrannini, Ele;Ferrario, Marco;Ferrieres, Jean;Florez, Jose C.;Ford, Ian;Fornage, Myriam;Franks, Paul W.;Frikke-Schmidt, Ruth;Galesloot, Tessel E;Gan, Wei;Gandin, Ilaria;Gasparini, Paolo;Giedraitis, Vilmantas;Giri, Ayush;Girotto, Giorgia;Gordon, Scott D;Gordon-Larsen, Penny;Gorski, Mathias;Grarup, Niels;Grove, Megan L;Gudnason, Vilmundur;Gustafsson, Stefan;Hansen, Torben;Harris, Kathleen Mullan;Harris, Tamara B.;Hattersley, Andrew T.;Hayward, Caroline;He, Liang;Heid, Iris M;Heikkilä, Kauko;Helgeland, Øyvind;Hernesniemi, Jussi;Hewitt, Alex W;Hocking, Lynne J.;Hollensted, Mette;Holmen, Oddgeir L.;Hovingh, G. Kees;Howson, Joanna M. M.;Hoyng, Carel B.;Huang, Paul L.;Hveem, Kristian;Ikram, M. Arfan;Ingelsson, Erik;Jackson, Anne U.;Jansson, Jan-Håkan;Jarvik, Gail P;Jensen, Gorm B.;Jhun, Min A.;Jia, Yucheng;Jiang, Xuejuan;Johansson, Stefan;Jørgensen, Marit E;Jørgensen, Torben;Jousilahti, Pekka;Jukema, J. Wouter;Kahali, Bratati;Kahn, René S;Kähönen, Mika;Kamstrup, Pia R.;Kanoni, Stavroula;Kaprio, Jaakko;Karaleftheri, Maria;Kardia, Sharon L. R.;Karpe, Fredrik;Kee, Frank;Keeman, Renske;Kiemeney, Lambertus A.;Kitajima, Hidetoshi;Kluivers, Kirsten B.;Kocher, Thomas;Komulainen, Pirjo;Kontto, Jukka;Kooner, Jaspal S;Kooperberg, Charles;Kovacs, Peter;Kriebel, Jennifer;Kuivaniemi, Helena;Küry, Sébastien;Kuusisto, Johanna;La Bianca, Martina;Laakso, Markku;Lakka, Timo A.;Lange, Ethan M;Lange, Leslie A.;Langefeld, Carl D.;Langenberg, Claudia;Larson, Eric B.;Lee, I. Te;Lehtimäki, Terho;Lewis, Cora E;Li, Huaixing;Li, Jin-Ping;Li-Gao, Ruifang;Lin, Honghuang;Lin, Li An;Lin, Xu;Lind, Lars;Lindström, Jaana;Linneberg, Allan;Liu, Yeheng;Liu, Yongmei;Lophatananon, Artitaya;Luan, Jian'an;Lubitz, Steven A;Lyytikäinen, Leo-Pekka;MacKey, David A.;Madden, Pamela A F;Manning, Alisa K.;Männistö, Satu;Marenne, Gaëlle;Marten, Jonathan;Martin, Nicholas G;Mazul, Angela L.;Meidtner, Karina;Metspalu, Andres;Mitchell, Paul D;Mohlke, Karen L.;Mook-Kanamori, Dennis O.;Morgan, Anna;Morris, Andrew D.;Morris, Andrew P.;Müller-Nurasyid, Martina;Munroe, Patricia B.;Nalls, Mike A;Nauck, Matthias;Nelson, Christopher P;Neville, Matt;Nielsen, Sune F;Nikus, Kjell;Njølstad, Pål R;Nordestgaard, Børge G;Ntalla, Ioanna;O'Connel, Jeffrey R.;Oksa, Heikki;Loohuis, Loes M Olde;Ophoff, Roel A.;Owen, Katharine R;Packard, Chris J.;Padmanabhan, Sandosh;Palmer, Colin N. A.;Pasterkamp, Gerard;Patel, Aniruddh P;Pattie, Alison;Pedersen, Oluf;Peissig, Peggy L.;Peloso, Gina M.;Pennell, Craig E.;Perola, Markus;Perry, James A.;Perry, John R. B.;Person, Thomas N.;Pirie, Ailith;Polasek, Ozren;Posthuma, Danielle;Raitakari, Olli T;Rasheed, Asif;Rauramaa, Rainer;Reilly, Dermot F;Reiner, Alex P;Renström, Frida;Ridker, Paul M.;Rioux, John D.;Robertson, Neil;Robino, Antonietta;Rolandsson, Olov;Rudan, Igor;Ruth, Katherine S.;Saleheen, Danish;Salomaa, Veikko;Samani, Nilesh J.;Sandow, Kevin;Sapkota, Yadav;Sattar, Naveed;Schmidt, Marjanka K;Schreiner, Pamela J;Schulze, Matthias B.;Scott, Robert A.;Segura-Lepe, Marcelo P.;Shah, Svati;Sim, Xueling;Sivapalaratnam, Suthesh;Small, Kerrin S.;Smith, Albert Vernon;Smith, Jennifer A;Southam, Lorraine;Spector, Timothy D;Speliotes, Elizabeth K;Starr, John M;Steinthorsdottir, Valgerdur;Stringham, Heather M.;Stumvoll, Michael;Surendran, Praveen;Hart't, Leen M.;Tansey, Katherine E.;Tardif, Jean-Claude;Taylor, Kent D;Teumer, Alexander;Thompson, Deborah J.;Thorsteinsdottir, Unnur;Thuesen, Betina H.;Tönjes, Anke;Tromp, Gerard;Trompet, Stella;Tsafantakis, Emmanouil;Tuomilehto, Jaakko;Tybjaerg-Hansen, Anne;Tyrer, Jonathan P;Uher, Rudolf;Uitterlinden, André G;Ulivi, Sheila;van der Laan, Sander W;Van Der Leij, Andries R.;van Duijn, Cornelia M;van Schoor, Natasja M.;van Setten, Jessica;Varbo, Anette;Varga, Tibor V.;Varma, Rohit;Velez Edwards, Digna R.;Vermeulen, Sita H;Vestergaard, Henrik;Vitart, Veronique;Vogt, Thomas F.;Vozzi, Diego;Walker, Mark;Wang, Feijie;Wang, Carol A.;Wang, Shuai;Wang, Yiqin;Wareham, Nicholas J;Warren, Helen R;Wessel, Jennifer;Willems, Sara M;Wilson, James G;Witte, Daniel R;Woods, Michael O;Wu, Ying;Yaghootkar, Hanieh;Yao, Jie;Yao, Tso-Pang;Yerges-Armstrong, Laura M.;Young, Robin;Zeggini, Eleftheria;Zhan, Xiaowei;Zhang, Weihua;Zhao, Jing Hua;Zhao, Wei;Zheng, He;Zhou, Wei;Rotter, Jerome I.;Boehnke, Michael;Kathiresan, Sekar;McCarthy, Mark I.;Willer, Cristen J.;Stefansson, Kari;Borecki, Ingrid B;Liu, Dajiang J;North, Kari E.;Heard-Costa, Nancy L;Pers, Tune H;Lindgren, Cecilia M.;Oxvig, Claus;Kutalik, Zoltán;Rivadeneira, Fernando;Loos, Ruth J F;Frayling, Timothy M.;Hirschhorn, Joel N.;Deloukas, Panos;Lettre, Guillaume;,;,;,;,;,;,;,;,;,
Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report 83 height-associated coding variants with lower minor-allele frequencie...
BACKGROUND: The non-communicable diseases dental caries and periodontal diseases pose an enormous burden on mankind. The dental biofilm is a major biological determinant common to the development of both diseases, and they share common risk factors a...