Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived sequences are more common in pathogenic than nonpathogenic taxa and are associated with changes in pathogen virulence. High abundance and mobilization of temperate p...
Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived sequences are more common in pathogenic than nonpathogenic taxa and are associated with changes in pathogen virulence. High abundance and mobilization of temperate p...
Bricio-Moreno, L;Sheridan, VH;Goodhead, I;Armstrong, S;Wong, JKL;Waters, EM;Sarsby, J;Panagiotou, S;Dunn, J;Chakraorty, A;Fang, Y;Griswold, KE;Winstanley, C;Fothergill, JL;Kadioglu, A;Neill, DR Pseudomonas aeruginosa colonises the upper airway of cystic fibrosis (CF) patients, providing a reservoir of host-adapted genotypes that subsequently establish chronic lung infection. We previously experimentally-evolved P. aeruginosa in a murine mod...
© 2017 by the authors. The ability of nitric oxide (NO)-releasing polymer coatings to prevent biofilm formation is described. NO-releasing coatings on (poly(ethylene terephthalate) (PET) and silicone elastomer (SE)) were fabricated using aminosilane ...
Hilliam, Y;Moore, MP;Lamont, IL;Bilton, D;Haworth, CS;Foweraker, J;Walshaw, MJ;Williams, D;Fothergill, JL;De Soyza, A;Winstanley, C To characterise Pseudomonas aeruginosa populations during chronic lung infections of non-cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the diversity of P. aeruginosa and the prevalence of multilineage infection...
Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived sequences are more common in pathogenic than nonpathogenic taxa and are associated with changes in pathogen virulence. High abundance and mobilization of temperate p...
Freschi, L.;Bertelli, C.;Jeukens, J.;Moore, M.P.;Kukavica-Ibrulj, I.;Emond-Rheault, J.G.;Hamel, J.;Fothergill, J.L.;Tucker, N.P.;McClean, S.;Klockgether, J.;de Soyza, A.;Brinkman, FSL;Levesque, R.C.;Winstanley, C. Pseudomonas aeruginosa is an important opportunistic pathogen, especially in the context of infections of cystic fibrosis (CF). In order to facilitate coordinated study of this pathogen, an international reference panel of P. aeruginosa isolates was ...
Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived sequences are more common in pathogenic than nonpathogenic taxa and are associated with changes in pathogen virulence. High abundance and mobilization of temperate p...
Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived sequences are more common in pathogenic than nonpathogenic taxa and are associated with changes in pathogen virulence. High abundance and mobilization of temperate p...
Hilliam, Y;Moore, MP;Lamont, IL;Bilton, D;Haworth, CS;Foweraker, J;Walshaw, MJ;Williams, D;Fothergill, JL;De Soyza, A;Winstanley, C To characterise Pseudomonas aeruginosa populations during chronic lung infections of non-cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the diversity of P. aeruginosa and the prevalence of multilineage infection...
