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Title
Background: Methotrexate (MTX) remains the cornerstone for therapy for rheumatoid arthritis yet research shows that non-adherence is significant and correlates with response to therapy.
Objective: In order to develop interventions to optimise methotrexate (MTX) use for the treatment of rheumatoid arthritis (RA) we evaluated the rate of, reasons for and predictors of MTX non-adherence during the first six months of therapy.