Adsorption-mediated self-assembly of ethyl cellulose (EC) nanoparticles at fluid interfaces, driven by reduction in interfacial energy, is shown to lead to stabilization of emulsions and foams. A multiscale approach is followed to address a number of...
Integration across decision levels of a supply chain is a key point in improving returns on investment. For example, planning and scheduling are usually carried out separately although they are interdependent of each other. Integration of planning an...
‘Bioinspiration’—using phenomena in biology to stimulate research in non-biological science and technology—is a strategy that suggests new areas for research. Beyond its potential to nucleate new ideas, bioinspiration has two other interesting charac...
Understanding dietary patterns is vital to reducing the number of people experiencing hunger (about 795 million), micronutrient deficiencies (2 billion), and overweight or obesity (2.1 billion). We characterize global trends in dietary quality by est...
Background: Low back pain is a highly prevalent health problem around the world, affecting 50% to 85% of people at some point in life. The purpose of this systematic review is to summarize the previous proton magnetic resonance spectroscopy studies o...
Pettengill, Matthew;Matute, Juan D.;Tresenriter, Megan;Hibbert, Julie;Burgner, David;Richmond, Peter;Luis Millán, José;Ozonoff, Al;Strunk, Tobias;Currie, Andrew;Levy, Ofer Background: A host defense function for Alkaline phosphatases (ALPs) is suggested by the contribution of intestinal ALP to detoxifying bacterial lipopolysaccharide (endotoxin) in animal models in vivo and the elevation of ALP activity following treat...
A major rate-limiting step for Aβ generation and deposition in Alzheimer’s disease brains is BACE1-mediated cleavage (β-cleavage) of the amyloid precursor protein (APP). We previously reported that APP undergoes palmitoylation at two cysteine residue...
Laíns, Inês;Duarte, Daniela;Barros, António S.;Martins, Ana Sofia;Gil, João;Miller, John B.;Marques, Marco;Mesquita, Tânia;Kim, Ivana K.;Cachulo, Maria da Luz;Vavvas, Demetrios;Carreira, Isabel M.;Murta, Joaquim N.;Silva, Rufino;Miller, Joan W.;Husain, Deeba;Gil, Ana M. Purpose To differentiate the plasma metabolomic profile of patients with age related macular degeneration (AMD) from that of controls, by Nuclear Magnetic Resonance (NMR) spectroscopy. Methods: Two cohorts (total of 396 subjects) representative of ce...
Mutations in the renal sodium-dependent phosphate co-transporters NPT2a and NPT2c have been reported in patients with renal stone disease and nephrocalcinosis, but the relative contribution of genotype, dietary calcium and phosphate to the formation ...
In single-particle cryo-electron microscopy (cryo-EM), K-means clustering algorithm is widely used in unsupervised 2D classification of projection images of biological macromolecules. 3D ab initio reconstruction requires accurate unsupervised classif...
