Selected Article


Forward Problem Model Neighborhood Relations Based on the Monte Carlo (MC) Simulation Photon Fluence Distributions


Forwardproblem model was created for the continuous wave (CW) biomedical diffuse opticimaging (DOI) modality. Forward problem model weight matrix functions werecalculated based on the photon’s Monte Carlo (MC) particle simulation model.Photon was thought as a particle, scattering and absorption events were actedinside the imaging tissue model. Doing this work has two main parts, the firstpart is running MC simulation program, the second part is transferring MCphoton fluencies from ANSI Standard C programming environment to the imagereconstruction platform, then translating or interpolating the photon fluencedistributions based on the imaging tissue mesh grid geometry, finally buildingthe forward problem model weight matrix by multiplying photon fluencies undereach source and detector positions. MC photon propagation code was run forseven-layer head model in ANSI standard C programming compiler under the Cygwinprompt. Absorption (µa), and scattering (µs) tissue opticcoefficients were selected as tough to mimic human head. Multi sources anddetectors were placed on imaging tissue, which is slab back-reflected geometry.Between each source and detector positions, calculated MC photon fluencedistributions were transferred from ANSI standard C code output data andtranslated by mathematical interpolation method to image reconstruction programmesh grid geometry. In order to do that, multi-source and detector matches weregrouped into sub-classes. Each class has different source-detector distance(SDS) group. Forward problem model weight matrix functions were calculated anddrawn in xy bird-eye and yz side-view. They were observed as they were predicted,successfully. This work involves grouping the same neighborhood weightfunctions appropriately.