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Locke, Adam E.;Kahali, Bratati;Berndt, Sonja I.;Justice, Anne E.;Pers, Tune H.;Day, Felix R.;Powell, Corey;Vedantam, Sailaja;Buchkovich, Martin L.;Yang, Jian;Croteau-Chonka, Damien C.;Esko, Tonu;Fall, Tove;Ferreira, Teresa;Gustafsson, Stefan;Kutalik, Zoltan;Luan, Jian'an;Maegi, Reedik;Randall, Joshua C.;Winkler, Thomas W.;Wood, Andrew R.;Workalemahu, Tsegaselassie;Faul, Jessica D.;Smith, Jennifer A.;Zhao, Jing Hua;Zhao, Wei;Chen, Jin;Fehrmann, Rudolf;Hedman, Asa K.;Karjalainen, Juha;Schmidt, Ellen M.;Absher, Devin;Amin, Najaf;Anderson, Denise;Beekman, Marian;Bolton, Jennifer L.;Bragg-Gresham, L.;Buyske, Steven;Demirkan, Ayse;Deng, Guohong;Ehret, Georg B.;Feenstra, Bjarke;Feitosa, Mary F.;Fischer, Krista;Goel, Anuj;Gong, Jian;Jackson, Anne U.;Kanoni, Stavroula;Kleber, Marcus E.;Kristiansson, Kati;Lim, Unhee;Lotay, Vaneet;Mangino, Massimo;Leach, Irene Mateo;Medina-Gomez, Carolina;Medland, Sarah E.;Nalls, Michael A.;Palmer, Cameron D.;Pasko, Dorota;Pechlivanis, Sonali;Peters, Marjolein J.;Prokopenko, Inga;Shungin, Dmitry;Stancakova, Alena;Strawbridge, Rona J.;Sung, Yun Ju;Tanaka, Toshiko;Teumer, Alexander;Trompet, Stella;van der Laan, Sander W.;van Setten, Jessica;Van Vliet-Ostaptchouk, Jana V.;Wang, Zhaoming;Yengo, Loic;Zhang, Weihua;Isaacs, Aaron;Albrecht, Eva;Arnlov, Johan;Arscott, Gillian M.;Attwood, Antony P.;Bandinelli, Stefania;Barrett, Amy;Bas, Isabelita N.;Bellis, Claire;Bennett, Amanda J.;Berne, Christian;Blagieva, Roza;Blueher, Matthias;Bohringer, Stefan;Bonnycastle, Lori L.;Boettcher, Yvonne;Boyd, Heather A.;Bruinenberg, Marcel;Caspersen, Ida H.;Chen, Yii-Der Ida;Clarke, Robert;Daw, E. Warwick;de Craen, Anton J. M.;Delgado, Graciela;Dimitriou, Maria;Doney, Alex S. F.;Eklund, Niina;Estrada, Karol;Eury, Elodie;Folkersen, Lasse;Fraser, Ross M.;Garcia, Melissa E.;Geller, Frank;Giedraitis, Vilmantas;Gigante, Bruna;Go, Alan S.;Golay, Alain;Goodall, Alison H.;Gordon, Scott D.;Gorski, Mathias;Grabe, Hans-Joergen;Grallert, Harald;Grammer, Tanja B.;Graessler, Jurgen;Gronberg, Henrik;Groves, Christopher J.;Gusto, Gaeelle;Haessler, Jeffrey;Hall, Per;Haller, Toomas;Hallmans, Goran;Hartman, Catharina A.;Hassinen, Maija;Hayward, Caroline;Heard-Costa, Nancy L.;Helmer, Qinta;Hengstenberg, Christian;Holmen, Oddgeir;Hottenga, Jouke-Jan;James, Alan L.;Jeff, Janina M.;Johansson, Asa;Jolley, Jennifer;Juliusdottir, Thorhildur;Kinnunen, Leena;Koenig, Wolfgang;Koskenvuo, Markku;Kratzer, Wolfgang;Laitinen, Jaana;Lamina, Claudia;Leander, Karin;Lee, Nanette R.;Lichtner, Peter;Lind, Lars;Lindstrom, Jaana;Lo, Ken Sin;Lobbens, Stephane;Lorbeer, Roberto;Lu, Yingchang;Mach, Francois;Magnusson, Patrik K. E.;Mahajan, Anubha;McArdle, Wendy L.;McLachlan, Stela;Menni, Cristina;Merger, Sigrun;Mihailov, Evelin;Milani, Lili;Moayyeri, Alireza;Monda, Keri L.;Morken, Mario A.;Mulas, Antonella;Mueller, Gabriele;Mueller-Nurasyid, Martina;Musk, Arthur W.;Nagaraja, Ramaiah;Noethen, Markus M.;Nolte, Ilja M.;Pilz, Stefan;Rayner, Nigel W.;Renstrom, Frida;Rettig, Rainer;Ried, Janina S.;Ripke, Stephan;Robertson, Neil R.;Rose, Lynda M.;Sanna, Serena;Scharnagl, Hubert;Scholtens, Salome;Schumacher, Fredrick R.;Scott, William R.;Seufferlein, Thomas;Shi, Jianxin;Smith, Albert Vernon;Smolonska, Joanna;Stanton, Alice V.;Steinthorsdottir, Valgerdur;Stirrups, Kathleen;Stringham, Heather M.;Sundstrom, Johan;Swertz, Morris A.;Swift, Amy J.;Syvanen, Ann-Christine;Tan, Sian-Tsung;Tayo, Bamidele O.;Thorand, Barbara;Thorleifsson, Gudmar;Tyrer, Jonathan P.;Uh, Hae-Won;Vandenput, Liesbeth;Verhulst, Frank C.;Vermeulen, Sita H.;Verweij, Niek;Vonk, Judith M.;Waite, Lindsay L.;Warren, Helen R.;Waterworth, Dawn;Weedon, Michael N.;Wilkens, Lynne R.;Willenborg, Christina;Wilsgaard, Tom;Wojczynski, Mary K.;Wong, Andrew;Wrightl, Alan F.;Zhang, Qunyuan;Brennan, Eoin P.;Choi, Murim;Dastani, Zari;Drong, Alexander W.;Eriksson, Per;Franco-Cereceda, Anders;Gadin, Jesper R.;Gharavi, Ali G.;Goddard, Michael E.;Handsaker, Robert E.;Huang, Jinyan;Karpe, Fredrik;Kathiresan, Sekar;Keildson, Sarah;Kiryluk, Krzysztof;Kubo, Michiaki;Lee, Jong-Young;Liang, Liming;Lifton, Richard P.;Ma, Baoshan;McCarroll, Steven A.;McKnight, Amy J.;Min, Josine L.;Moffatt, Miriam F.;Montgomery, Grant W.;Murabito, Joanne M.;Nicholson, George;Nyholt, Dale R.;Okada, Yukinori;Perry, John R. B.;Dorajoo, Rajkumar;Reinmaa, Eva;Salem, Rany M.;Sandholm, Niina;Scott, Robert A.;Stolk, Lisette;Takahashi, Atsushi;Tanaka, Toshihiro;van 't Hooft, Ferdinand M.;Vinkhuyzen, Anna A. E.;Westra, Harm-Jan;Zheng, Wei;Zondervan, Krina T.;Heath, Andrew C.;Arveiler, Dominique;Bakker, Stephan J. L.;Beilby, John;Bergman, Richard N.;Blangero, John;Bovet, Pascal;Campbell, Harry;Caulfield, Mark J.;Cesana, Giancarlo;Chakravarti, Aravinda;Chasman, Daniel I.;Chines, Peter S.;Collins, Francis S.;Crawford, Dana C.;Cupples, L. Adrienne;Cusi, Daniele;Danesh, John;de Faire, Ulf;den Ruijter, Hester M.;Dominiczak, Anna F.;Erbel, Raimund;Erdmann, Jeanette;Eriksson, Johan G.;Farrall, Martin;Felix, Stephan B.;Ferrannini, Ele;Ferrieres, Jean;Ford, Ian;Forouhi, Nita G.;Forrester, Terrence;Franco, Oscar H.;Gansevoort, Ron T.;Gejman, Pablo V.;Gieger, Christian;Gottesman, Omri;Gudnason, Vilmundur;Gyllensten, Ulf;Hall, Alistair S.;Harris, Tamara B.;Hattersley, Andrew T.;Hicks, Andrew A.;Hindorff, Lucia A.;Hingorani, Aroon D.;Hofman, Albert;Homuth, Georg;Hovingh, G. Kees;Humphries, Steve E.;Hunt, Steven C.;Hypponen, Elina;Illig, Thomas;Jacobs, Kevin B.;Jarvelin, Marjo-Riitta;Joeckel, Karl-Heinz;Johansen, Berit;Jousilahti, Pekka;Jukema, J. Wouter;Jula, Antti M.;Kaprio, Jaakko;Kastelein, John J. P.;Keinanen-Kiukaanniemi, Sirkka M.;Kiemeney, Lambertus A.;Knekt, Paul;Kooner, Jaspal S.;Kooperberg, Charles;Kovacs, Peter;Kraja, Aldi T.;Kumari, Meena;Kuusisto, Johanna;Lakka, Timo A.;Langenberg, Claudia;Le Marchand, Laic;Lehtimaki, Terho;Lyssenko, Valeriya;Mannisto, Satu;Marette, Andre;Matise, Tara C.;McKenzie, Colin A.;McKnight, Barbara;Moll, Frans L.;Morris, Andrew D.;Morris, Andrew P.;Murray, Jeffrey C.;Nelis, Mari;Ohlsson, Claes;Oldehinkel, Albertine J.;Ong, Ken K.;Madden, Pamela A. F.;Pasterkamp, Gerard;Peden, John F.;Peters, Annette;Postma, Dirkje S.;Pramstaller, Peter P.;Price, Jackie F.;Qi, Lu;Raitakari, Olli T.;Rankinen, Tuomo;Rao, D. C.;Rice, Treva K.;Ridker, Paul M.;Rioux, John D.;Ritchie, Marylyn D.;Rudan, Igor;Salomaa, Veikko;Samani, Nilesh J.;Saramines, Jouko;Sarzynski, Mark A.;Schunkert, Heribert;Schwarz, Peter E. H.;Sever, Peter;Shuldiner, Alan R.;Sinisalo, Juha;Stolk, Ronald P.;Strauch, Konstantin;Toenjes, Anke;Tregouet, David-Alexandre;Tremblay, Angelo;Tremoli, Elena;Virtamo, Jarmo;Vohl, Marie-Claude;Voelker, Uwe;Waeber, Gerard;Willemsen, Gonneke;Witteman, Jacqueline C.;Zillikens, M. Carola;Adair, Linda S.;Amouyel, Philippe;Asselbergs, Folkert W.;Assimes, Themistocles L.;Bochud, Murielle;Boehm, Bernhard O.;Boerwinkle, Eric;Bornstein, Stefan R.;Bottinger, Erwin P.;Bouchard, Claude;Cauchi, Stephane;Chambers, John C.;Chanock, Stephen J.;Cooper, Richard S.;de Bakker, Paul I. W.;Dedoussis, George;Ferrucci, Luigi;Franks, Paul W.;Froguel, Philippe;Groop, Leif C.;Haiman, Christopher A.;Hamsten, Anders;Hui, Jennie;Hunter, David J.;Hveem, Kristian;Kaplan, Robert C.;Kivimaki, Mika;Kuh, Diana;Laakso, Markku;Liu, Yongmei;Martin, Nicholas G.;Maerz, Winfried;Melbve, Mads;Metspalu, Andres;Moebus, Susanne;Munroe, Patricia B.;Njolstad, Inger;Oostra, Ben A.;Palmer, Colin N. A.;Pedersen, Nancy L.;Perola, Markus;Perusse, Louis;Peters, Ulrike;Power, Chris;Quertermous, Thomas;Rauramaa, Rainer;Rivadeneira, Fernando;Saaristo, Timo E.;Saleheen, Danish;Sattar, Naveed;Schadt, Eric E.;Schlessinger, David;Slagboom, P. Eline;Snieder, Harold;Spector, Tim D.;Thorsteinsdottir, Unnu R.;Stumvoll, Michael;Tuomilehto, Jaakko;Uitterlinden, Andre G.;Uusitupa, Matti;van der Harst, Pim;Walker, Mark;Wallaschofski, Henri;Wareham, Nicholas J.;Watkins, Hugh;Weir, David R.;Wichmann, H-Erich;Wilson, James F.;Zanen, Pieter;Borecki, Ingrid B.;Deloukas, Panos;Fox, Caroline S.;Heid, Iris M.;O'Connell, Jeffrey R.;Strachan, David P.;Stefansson, Kari;van Duijri, Cornelia M.;Abecasis, Goncalo R.;Franke, Lude;Frayling, Timothy M.;McCarthy, Mark I.;Visscher, Peter M.;Scherag, Andre;Willer, Cristen J.;Boehnke, Michael;Mohlke, Karen L.;Lindgren, Cecilia M.;Beckmann, Jacques S.;Barroso, Ines;North, Kari E.;Ingelsson, Erik;Hirschhorn, Joel N.;Loos, Ruth J. F.;Speliotes, Elizabeth K.;Peeters, P;Broekmans, FJM;van Gils, CH;van der Schouw, YT;Fauser, BCJM;Uiterwaal, C.S.P.M.;Bots, Michael L
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity...
Winkler, Thomas W.;Justice, Anne E.;Graff, Mariaelisa;Barata, Llilda;Feitosa, Mary F.;Chu, Su;Czajkowski, Jacek;Esko, Tonu;Fall, Tove;Kilpelainen, Tuomas O.;Lu, Yingchang;Magi, Reedik;Mihailov, Evelin;Pers, Tune H.;Rueeger, Sina;Teumer, Alexander;Ehret, Georg B.;Ferreira, Teresa;Heard-Costa, Nancy L.;Karjalainen, Juha;Lagou, Vasiliki;Mahajan, Anubha;Neinast, Michael D.;Prokopenko, Inga;Simino, Jeannette;Teslovich, Tanya M.;Jansen, Rick;Westra, Harm-Jan;White, Charles C.;Absher, Devin;Ahluwalia, Tarunveer S.;Ahmad, Shafqat;Albrecht, Eva;Alves, Alexessander Couto;Bragg-Gresham, Jennifer L.;de Craen, Anton J. M.;Bis, Joshua C.;Bonnefond, Amelie;Boucher, Gabrielle;Cadby, Gemma;Cheng, Yu-Ching;Chiang, Charleston W. K.;Delgado, Graciela;Demirkan, Ayse;Dueker, Nicole;Eklund, Niina;Eiriksdottir, Gudny;Eriksson, Joel;Feenstra, Bjarke;Fischer, Krista;Frau, Francesca;Galesloot, Tessel E.;Geller, Frank;Goel, Anuj;Gorski, Mathias;Grammer, Tanja B.;Gustafsson, Stefan;Haitjema, Saskia;Hottenga, Jouke-Jan;Huffman, Jennifer E.;Jackson, Anne U.;Jacobs, Kevin B.;Johansson, Asa;Kaakinen, Marika;Kleber, Marcus E.;Lahti, Jari;Leach, Irene Mateo;Lehne, Benjamin;Liu, Youfang;Lo, Ken Sin;Lorentzon, Mattias;Luan, Jian'an;Madden, Pamela A. F.;Mangino, Massimo;McKnight, Barbara;Medina-Gomez, Carolina;Monda, Keri L.;Montasser, May E.;Mueller, Gabriele;Mueller-Nurasyid, Martina;Nolte, Ilja M.;Panoutsopoulou, Kalliope;Pascoe, Laura;Paternoster, Lavinia;Rayner, Nigel W.;Renstrom, Frida;Rizzi, Federica;Rose, Lynda M.;Ryan, Kathy A.;Salo, Perttu;Sanna, Serena;Scharnagl, Hubert;Shi, Jianxin;Smith, Albert Vernon;Southam, Lorraine;Stancakova, Alena;Steinthorsdottir, Valgerdur;Strawbridge, Rona J.;Sung, Yun Ju;Tachmazidou, Ioanna;Tanaka, Toshiko;Thorleifsson, Gudmar;Trompet, Stella;Pervjakova, Natalia;Tyrer, Jonathan P.;Vandenput, Liesbeth;van der Laan, Sander W.;van der Velde, Nathalie;van Setten, Jessica;van Vliet-Ostaptchouk, Jana V.;Verweij, Niek;Vlachopoulou, Efthymia;Waite, Lindsay L.;Wang, Sophie R.;Wang, Zhaoming;Wild, Sarah H.;Willenborg, Christina;Wilson, James F.;Wong, Andrew;Yang, Jian;Yengo, Loic;Yerges-Armstrong, Laura M.;Yu, Lei;Zhang, Weihua;Zhao, Jing Hua;Andersson, Ehm A.;Bakker, Stephan J. L.;Baldassarre, Damiano;Banasik, Karina;Barcella, Matteo;Barlassina, Cristina;Bellis, Claire;Benaglio, Paola;Blangero, John;Blueher, Matthias;Bonnet, Fabrice;Bonnycastle, Lori L.;Boyd, Heather A.;Bruinenberg, Marcel;Buchman, Aron S.;Campbell, Harry;Chen, Yii-Der Ida;Chines, Peter S.;Claudi-Boehm, Simone;Cole, John;Collins, Francis S.;de Geus, Eco J. C.;de Groot, Lisette C. P. G. M.;Dimitriou, Maria;Duan, Jubao;Enroth, Stefan;Eury, Elodie;Farmaki, Aliki-Eleni;Forouhi, Nita G.;Friedrich, Nele;Gejman, Pablo V.;Gigante, Bruna;Glorioso, Nicola;Go, Alan S.;Gottesman, Omri;Graessler, Juergen;Grallert, Harald;Grarup, Niels;Gu, Yu-Mei;Broer, Linda;Ham, Annelies C.;Hansen, Torben;Harris, Tamara B.;Hartman, Catharina A.;Hassinen, Maija;Hastie, Nicholas;Hattersley, Andrew T.;Heath, Andrew C.;Henders, Anjali K.;Hernandez, Dena;Hillege, Hans;Holmen, Oddgeir;Hovingh, Kees G.;Hui, Jennie;Husemoen, Lise L.;Hutri-Kahonen, Nina;Hysi, Pirro G.;Illig, Thomas;De Jager, Philip L.;Jalilzadeh, Shapour;Jorgensen, Torben;Jukema, J. Wouter;Juonala, Markus;Kanoni, Stavroula;Karaleftheri, Maria;Khaw, Kay Tee;Kinnunen, Leena;Kittner, Steven J.;Koenig, Wolfgang;Kolcic, Ivana;Kovacs, Peter;Krarup, Nikolaj T.;Kratzer, Wolfgang;Krueger, Janine;Kuh, Diana;Kumari, Meena;Kyriakou, Theodosios;Langenberg, Claudia;Lannfelt, Lars;Lanzani, Chiara;Lotay, Vaneet;Launer, Lenore J.;Leander, Karin;Lindstrom, Jaana;Linneberg, Allan;Liu, Yan-Ping;Lobbens, Stephane;Luben, Robert;Lyssenko, Valeriya;Mannisto, Satu;Magnusson, Patrik K.;McArdle, Wendy L.;Menni, Cristina;Merger, Sigrun;Milani, Lili;Montgomery, Grant W.;Morris, Andrew P.;Narisu, Narisu;Nelis, Mari;Ong, Ken K.;Palotie, Aarno;Perusse, Louis;Pichler, Irene;Pilia, Maria G.;Pouta, Anneli;Rheinberger, Myriam;Ribel-Madsen, Rasmus;Richards, Marcus;Rice, Kenneth M.;Rice, Treva K.;Rivolta, Carlo;Salomaa, Veikko;Sanders, Alan R.;Sarzynski, Mark A.;Scholtens, Salome;Scott, Robert A.;Scott, William R.;Sebert, Sylvain;Sengupta, Sebanti;Sennblad, Bengt;Seufferlein, Thomas;Silveira, Angela;Slagboom, P. Eline;Smit, Jan H.;Sparso, Thomas H.;Stirrups, Kathleen;Stolk, Ronald P.;Stringham, Heather M.;Swertz, Morris A.;Swift, Amy J.;Syvanen, Ann-Christine;Tan, Sian-Tsung;Thorand, Barbara;Toenjes, Anke;Tremblay, Angelo;Tsafantakis, Emmanouil;van der Most, Peter J.;Voelker, Uwe;Vohl, Marie-Claude;Vonk, Judith M.;Waldenberger, Melanie;Walker, Ryan W.;Wennauer, Roman;Widen, Elisabeth;Willemsen, Gonneke;Wilsgaard, Tom;Wright, Alan F.;Zillikens, M. Carola;van Dijk, Suzanne C.;van Schoor, Natasja M.;Asselbergs, Folkert W.;de Bakker, Paul I. W.;Beckmann, Jacques S.;Beilby, John;Bennett, David A.;Bergman, Richard N.;Bergmann, Sven;Boeger, Carsten A.;Boehm, Bernhard O.;Boerwinkle, Eric;Boomsma, Dorret I.;Bornstein, Stefan R.;Bottinger, Erwin P.;Bouchard, Claude;Chambers, John C.;Chanock, Stephen J.;Chasman, Daniel I.;Cucca, Francesco;Cusi, Daniele;Dedoussis, George;Erdmann, Jeanette;Eriksson, Johan G.;Evans, Denis A.;de Faire, Ulf;Farrall, Martin;Ferrucci, Luigi;Ford, Ian;Franke, Lude;Franks, Paul W.;Froguel, Philippe;Gansevoort, Ron T.;Gieger, Christian;Gronberg, Henrik;Gudnason, Vilmundur;Gyllensten, Ulf;Hall, Per;Hamsten, Anders;van der Harst, Pim;Hayward, Caroline;Heliovaara, Markku;Hengstenberg, Christian;Hicks, Andrew A.;Hingorani, Aroon;Hofman, Albert;Hu, Frank;Huikuri, Heikki V.;Hveem, Kristian;James, Alan L.;Jordan, Joanne M.;Jula, Antti;Kaehoenen, Mika;Kajantie, Eero;Kathiresan, Sekar;Kiemeney, Lambertus A. L. M.;Kivimaki, Mika;Knekt, Paul B.;Koistinen, Heikki A.;Kooner, Jaspal S.;Koskinen, Seppo;Kuusisto, Johanna;Maerz, Winfried;Martin, Nicholas G.;Laakso, Markku;Lakka, Timo A.;Lehtimaki, Terho;Lettre, Guillaume;Levinson, Douglas F.;Lind, Lars;Lokki, Marja-Liisa;Mantyselka, Pekka;Melbye, Mads;Metspalu, Andres;Mitchell, Braxton D.;Moll, Frans L.;Murray, Jeffrey C.;Musk, Arthur W.;Nieminen, Markku S.;Njolstad, Inger;Ohlsson, Claes;Oldehinkel, Albertine J.;Oostra, Ben A.;Palmer, Lyle J.;Pankow, James S.;Pasterkamp, Gerard;Pedersen, Nancy L.;Pedersen, Oluf;Penninx, Brenda W.;Perola, Markus;Peters, Annette;Polasek, Ozren;Pramstaller, Peter P.;Psaty, Bruce M.;Qi, Lu;Quertermous, Thomas;Raitakari, Olli T.;Rankinen, Tuomo;Rauramaa, Rainer;Ridker, Paul M.;Rioux, John D.;Rivadeneira, Fernando;Rotter, Jerome I.;Rudan, Igor;den Ruijter, Hester M.;Saltevo, Juha;Sattar, Naveed;Schunkert, Heribert;Schwarz, Peter E. H.;Shuldiner, Alan R.;Sinisalo, Juha;Snieder, Harold;Sorensen, Thorkild I. A.;Spector, Tim D.;Staessen, Jan A.;Stefania, Bandinelli;Thorsteinsdottir, Unnur;Stumvoll, Michael;Tardif, Jean-Claude;Tremoli, Elena;Tuomilehto, Jaakko;Uitterlinden, Andre G.;Uusitupa, Matti;Verbeek, Andre L. M.;Vermeulen, Sita H.;Viikari, Jorma S.;Vitart, Veronique;Voelzke, Henry;Vollenweider, Peter;Waeber, Gerard;Walker, Mark;Wallaschofski, Henri;Wareham, Nicholas J.;Watkins, Hugh;Zeggini, Eleftheria;Chakravarti, Aravinda;Clegg, Deborah J.;Cupples, L. Adrienne;Gordon-Larsen, Penny;Jaquish, Cashell E.;Rao, D. C.;Abecasis, Goncalo R.;Assimes, Themistocles L.;Barroso, Ines;Berndt, Sonja I.;Boehnke, Michael;Deloukas, Panos;Fox, Caroline S.;Groop, Leif C.;Hunter, David J.;Ingelsson, Erik;Kaplan, Robert C.;McCarthy, Mark I.;Mohlke, Karen L.;O'Connell, Jeffrey R.;Schlessinger, David;Strachan, David P.;Stefansson, Kari;van Duijn, Cornelia M.;Hirschhorn, Joel N.;Lindgren, Cecilia M.;Heid, Iris M.;North, Kari E.;Borecki, Ingrid B.;Kutalik, Zoltan;Loos, Ruth J. F.;CHARGE Consortium;DIAGRAM Consortium;GLGC Consortium;Global-BPGen Consortium;ICBP Consortium;MAGIC Consortium
Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow...
BACKGROUND : Mortality and morbidity are higher among patients with atrial fibrillation and heart failure than among those with heart failure alone. Catheter ablation for atrial fibrillation has been proposed as a means of improving outcomes among pa...
BACKGROUND : Mortality and morbidity are higher among patients with atrial fibrillation and heart failure than among those with heart failure alone. Catheter ablation for atrial fibrillation has been proposed as a means of improving outcomes among pa...
Background We previously reported association of SCARB1 SNP rs10846744 with common carotid IMT (cIMT) and cardiovascular disease (CVD) events. Since rs10846744 has been reported in association with Lp-PLA(2) mass and activity, we hypothesized that in...
Background: Aortic valve stenosis (AVS) and coronary artery disease (CAD) have a significant genetic contribution and commonly co-exist. To compare and contrast genetic determinants of the two diseases, we investigated associations of the LPA and 9p2...
Winkler, Thomas W;Justice, Anne E;Graff, Mariaelisa;Barata, Llilda;Feitosa, Mary F;Chu, Su;Czajkowski, Jacek;Esko, Tõnu;Fall, Tove;Kilpeläinen, Tuomas O;Lu, Yingchang;Mägi, Reedik;Mihailov, Evelin;Pers, Tune H;Rüeger, Sina;Teumer, Alexander;Ehret, Georg B;Ferreira, Teresa;Heard-Costa, Nancy L;Karjalainen, Juha;Lagou, Vasiliki;Mahajan, Anubha;Neinast, Michael D;Prokopenko, Inga;Simino, Jeannette;Teslovich, Tanya M;Jansen, Rick;Westra, Harm-Jan;White, Charles C;Absher, Devin;Ahluwalia, Tarunveer S;Ahmad, Shafqat;Albrecht, Eva;Alves, Alexessander Couto;Bragg-Gresham, Jennifer L;de Craen, Anton JM;Bis, Joshua C;Bonnefond, Amélie;Boucher, Gabrielle;Cadby, Gemma;Cheng, Yu-Ching;Chiang, Charleston WK;Delgado, Graciela;Demirkan, Ayse;Dueker, Nicole;Eklund, Niina;Eiriksdottir, Gudny;Eriksson, Joel;Feenstra, Bjarke;Fischer, Krista;Frau, Francesca;Galesloot, Tessel E;Geller, Frank;Goel, Anuj;Gorski, Mathias;Grammer, Tanja B;Gustafsson, Stefan;Haitjema, Saskia;Hottenga, Jouke-Jan;Huffman, Jennifer E;Jackson, Anne U;Jacobs, Kevin B;Johansson, Åsa;Kaakinen, Marika;Kleber, Marcus E;Lahti, Jari;Mateo Leach, Irene;Lehne, Benjamin;Liu, Youfang;Lo, Ken Sin;Lorentzon, Mattias;Luan, Jian'an;Madden, Pamela AF;Mangino, Massimo;McKnight, Barbara;Medina-Gomez, Carolina;Monda, Keri L;Montasser, May E;Müller, Gabriele;Müller-Nurasyid, Martina;Nolte, Ilja M;Panoutsopoulou, Kalliope;Pascoe, Laura;Paternoster, Lavinia;Rayner, Nigel W;Renström, Frida;Rizzi, Federica;Rose, Lynda M;Ryan, Kathy A;Salo, Perttu;Sanna, Serena;Scharnagl, Hubert;Shi, Jianxin;Smith, Albert Vernon;Southam, Lorraine;Stančáková, Alena;Steinthorsdottir, Valgerdur;Strawbridge, Rona J;Sung, Yun Ju;Tachmazidou, Ioanna;Tanaka, Toshiko;Thorleifsson, Gudmar;Trompet, Stella;Pervjakova, Natalia;Tyrer, Jonathan P;Vandenput, Liesbeth;van der Laan, Sander W;van der Velde, Nathalie;van Setten, Jessica;van Vliet-Ostaptchouk, Jana V;Verweij, Niek;Vlachopoulou, Efthymia;Waite, Lindsay L;Wang, Sophie R;Wang, Zhaoming;Wild, Sarah H;Willenborg, Christina;Wilson, James F;Wong, Andrew;Yang, Jian;Yengo, Loïc;Yerges-Armstrong, Laura M;Yu, Lei;Zhang, Weihua;Zhao, Jing Hua;Andersson, Ehm A;Bakker, Stephan JL;Baldassarre, Damiano;Banasik, Karina;Barcella, Matteo;Barlassina, Cristina;Bellis, Claire;Benaglio, Paola;Blangero, John;Blüher, Matthias;Bonnet, Fabrice;Bonnycastle, Lori L;Boyd, Heather A;Bruinenberg, Marcel;Buchman, Aron S;Campbell, Harry;Chen, Yii-Der Ida;Chines, Peter S;Claudi-Boehm, Simone;Cole, John;Collins, Francis S;de Geus, Eco JC;de Groot, Lisette CPGM;Dimitriou, Maria;Duan, Jubao;Enroth, Stefan;Eury, Elodie;Farmaki, Aliki-Eleni;Forouhi, Nita Gandhi;Friedrich, Nele;Gejman, Pablo V;Gigante, Bruna;Glorioso, Nicola;Go, Alan S;Gottesman, Omri;Gräßler, Jürgen;Grallert, Harald;Grarup, Niels;Gu, Yu-Mei;Broer, Linda;Ham, Annelies C;Hansen, Torben;Harris, Tamara B;Hartman, Catharina A;Hassinen, Maija;Hastie, Nicholas;Hattersley, Andrew T;Heath, Andrew C;Henders, Anjali K;Hernandez, Dena;Hillege, Hans;Holmen, Oddgeir;Hovingh, Kees G;Hui, Jennie;Husemoen, Lise L;Hutri-Kähönen, Nina;Hysi, Pirro G;Illig, Thomas;De Jager, Philip L;Jalilzadeh, Shapour;Jørgensen, Torben;Jukema, J Wouter;Juonala, Markus;Kanoni, Stavroula;Karaleftheri, Maria;Khaw, Kay-Tee;Kinnunen, Leena;Kittner, Steven J;Koenig, Wolfgang;Kolcic, Ivana;Kovacs, Peter;Krarup, Nikolaj T;Kratzer, Wolfgang;Krüger, Janine;Kuh, Diana;Kumari, Meena;Kyriakou, Theodosios;Langenberg, Claudia;Lannfelt, Lars;Lanzani, Chiara;Lotay, Vaneet;Launer, Lenore J;Leander, Karin;Lindström, Jaana;Linneberg, Allan;Liu, Yan-Ping;Lobbens, Stéphane;Luben, Robert;Lyssenko, Valeriya;Männistö, Satu;Magnusson, Patrik K;McArdle, Wendy L;Menni, Cristina;Merger, Sigrun;Milani, Lili;Montgomery, Grant W;Morris, Andrew P;Narisu, Narisu;Nelis, Mari;Ong, Ken;Palotie, Aarno;Pérusse, Louis;Pichler, Irene;Pilia, Maria G;Pouta, Anneli;Rheinberger, Myriam;Ribel-Madsen, Rasmus;Richards, Marcus;Rice, Kenneth M;Rice, Treva K;Rivolta, Carlo;Salomaa, Veikko;Sanders, Alan R;Sarzynski, Mark A;Scholtens, Salome;Scott, Robert;Scott, William R;Sebert, Sylvain;Sengupta, Sebanti;Sennblad, Bengt;Seufferlein, Thomas;Silveira, Angela;Slagboom, P Eline;Smit, Jan H;Sparsø, Thomas H;Stirrups, Kathleen Elizabeth;Stolk, Ronald P;Stringham, Heather M;Swertz, Morris A;Swift, Amy J;Syvänen, Ann-Christine;Tan, Sian-Tsung;Thorand, Barbara;Tönjes, Anke;Tremblay, Angelo;Tsafantakis, Emmanouil;van der Most, Peter J;Völker, Uwe;Vohl, Marie-Claude;Vonk, Judith M;Waldenberger, Melanie;Walker, Ryan W;Wennauer, Roman;Widén, Elisabeth;Willemsen, Gonneke;Wilsgaard, Tom;Wright, Alan F;Zillikens, M Carola;van Dijk, Suzanne C;van Schoor, Natasja M;Asselbergs, Folkert W;de Bakker, Paul IW;Beckmann, Jacques S;Beilby, John;Bennett, David A;Bergman, Richard N;Bergmann, Sven;Böger, Carsten A;Boehm, Bernhard O;Boerwinkle, Eric;Boomsma, Dorret I;Bornstein, Stefan R;Bottinger, Erwin P;Bouchard, Claude;Chambers, John C;Chanock, Stephen J;Chasman, Daniel I;Cucca, Francesco;Cusi, Daniele;Dedoussis, George;Erdmann, Jeanette;Eriksson, Johan G;Evans, Denis A;de Faire, Ulf;Farrall, Martin;Ferrucci, Luigi;Ford, Ian;Franke, Lude;Franks, Paul W;Froguel, Philippe;Gansevoort, Ron T;Gieger, Christian;Grönberg, Henrik;Gudnason, Vilmundur;Gyllensten, Ulf;Hall, Per;Hamsten, Anders;van der Harst, Pim;Hayward, Caroline;Heliövaara, Markku;Hengstenberg, Christian;Hicks, Andrew A;Hingorani, Aroon;Hofman, Albert;Hu, Frank;Huikuri, Heikki V;Hveem, Kristian;James, Alan L;Jordan, Joanne M;Jula, Antti;Kähönen, Mika;Kajantie, Eero;Kathiresan, Sekar;Kiemeney, Lambertus ALM;Kivimaki, Mika;Knekt, Paul B;Koistinen, Heikki A;Kooner, Jaspal S;Koskinen, Seppo;Kuusisto, Johanna;Maerz, Winfried;Martin, Nicholas G;Laakso, Markku;Lakka, Timo A;Lehtimäki, Terho;Lettre, Guillaume;Levinson, Douglas F;Lind, Lars;Lokki, Marja-Liisa;Mäntyselkä, Pekka;Melbye, Mads;Metspalu, Andres;Mitchell, Braxton D;Moll, Frans L;Murray, Jeffrey C;Musk, Arthur W;Nieminen, Markku S;Njølstad, Inger;Ohlsson, Claes;Oldehinkel, Albertine J;Oostra, Ben A;Palmer, Lyle J;Pankow, James S;Pasterkamp, Gerard;Pedersen, Nancy L;Pedersen, Oluf;Penninx, Brenda W;Perola, Markus;Peters, Annette;Polašek, Ozren;Pramstaller, Peter P;Psaty, Bruce M;Qi, Lu;Quertermous, Thomas;Raitakari, Olli T;Rankinen, Tuomo;Rauramaa, Rainer;Ridker, Paul M;Rioux, John D;Rivadeneira, Fernando;Rotter, Jerome I;Rudan, Igor;den Ruijter, Hester M;Saltevo, Juha;Sattar, Naveed;Schunkert, Heribert;Schwarz, Peter EH;Shuldiner, Alan R;Sinisalo, Juha;Snieder, Harold;Sørensen, Thorkild IA;Spector, Tim D;Staessen, Jan A;Stefania, Bandinelli;Thorsteinsdottir, Unnur;Stumvoll, Michael;Tardif, Jean-Claude;Tremoli, Elena;Tuomilehto, Jaakko;Uitterlinden, André G;Uusitupa, Matti;Verbeek, André LM;Vermeulen, Sita H;Viikari, Jorma S;Vitart, Veronique;Völzke, Henry;Vollenweider, Peter;Waeber, Gérard;Walker, Mark;Wallaschofski, Henri;Wareham, Nicholas John;Watkins, Hugh;Zeggini, Eleftheria;CHARGE Consortium,;DIAGRAM Consortium,;GLGC Consortium,;Global-BPGen Consortium,;ICBP Consortium,;MAGIC Consortium,;Chakravarti, Aravinda;Clegg, Deborah J;Cupples, L Adrienne;Gordon-Larsen, Penny;Jaquish, Cashell E;Rao, DC;Abecasis, Goncalo R;Assimes, Themistocles L;Barroso, Ines;Berndt, Sonja I;Boehnke, Michael;Deloukas, Panos;Fox, Caroline S;Groop, Leif C;Hunter, David J;Ingelsson, Erik;Kaplan, Robert C;McCarthy, Mark I;Mohlke, Karen L;O'Connell, Jeffrey R;Schlessinger, David;Strachan, David P;Stefansson, Kari;van Duijn, Cornelia M;Hirschhorn, Joel N;Lindgren, Cecilia M;Heid, Iris M;North, Kari E;Borecki, Ingrid B;Kutalik, Zoltán;Loos, Ruth JF
Glatiramer acetate is used therapeutically in multiple sclerosis but also known for adverse effects including elevated coronary artery disease (CAD) risk. The mechanisms underlying the cardiovascular side effects of the medication are unclear. Here, ...
Scott, Robert;Freitag, Daniel F;Li, Li;Chu, Audrey Y;Surendran, Praveen;Young, Robin;Grarup, Niels;Stancáková, Alena;Chen, Yuning;Varga, Tibor V;Yaghootkar, Hanieh;Luan, Jian'an;Zhao, Jing Hua;Willems, Sara Marie;Wessel, Jennifer;Wang, Shuai;Maruthur, Nisa;Michailidou, Kyriaki;Pirie, Ailith;van, der Lee Sven J;Gillson, Christopher;Al, Olama Ali Amin;Amouyel, Philippe;Arriola, Larraitz;Arveiler, Dominique;Aviles-Olmos, Iciar;Balkau, Beverley;Barricarte, Aurelio;Barroso, Ines;Garcia, Sara Benlloch;Bis, Joshua C;Blankenberg, Stefan;Boehnke, Michael;Boeing, Heiner;Boerwinkle, Eric;Borecki, Ingrid B;Bork-Jensen, Jette;Bowden, Sarah;Caldas, Carlos Manuel;Caslake, Muriel;Cupples, L Adrienne;Cruchaga, Carlos;Czajkowski, Jacek;den, Hoed Marcel;Dunn, Janet A;Earl, Helena Margaret;Ehret, Georg B;Ferrannini, Ele;Ferrieres, Jean;Foltynie, Thomas;Ford, Ian;Forouhi, Nita Gandhi;Gianfagna, Francesco;Gonzalez, Carlos;Grioni, Sara;Hiller, Louise;Jansson, Jan-Håkan;Jørgensen, Marit E;Jukema, J Wouter;Kaaks, Rudolf;Kee, Frank;Kerrison, Nicola D;Key, Timothy J;Kontto, Jukka;Kote-Jarai, Zsofia;Kraja, Aldi T;Kuulasmaa, Kari;Kuusisto, Johanna;Linneberg, Allan;Liu, Chunyu;Marenne, Gaëlle;Mohlke, Karen L;Morris, Andrew P;Muir, Kenneth;Müller-Nurasyid, Martina;Munroe, Patricia B;Navarro, Carmen;Nielsen, Sune F;Nilsson, Peter M;Nordestgaard, Børge G;Packard, Chris J;Palli, Domenico;Panico, Salvatore;Peloso, Gina M;Perola, Markus;Peters, Annette;Poole, Christopher J;Quirós, J Ramón;Rolandsson, Olov;Sacerdote, Carlotta;Salomaa, Veikko;Sánchez, María-José;Sattar, Naveed;Sharp, Stephen John;Sims, Rebecca;Slimani, Nadia;Smith, Jennifer A;Thompson, Deborah Jane;Trompet, Stella;Tumino, Rosario;van, der A Daphne L;van, der Schouw Yvonne T;Virtamo, Jarmo;Walker, Mark;Walter, Klaudia;Abraham, Jean Elizabeth;Amundadottir, Laufey T;Aponte, Jennifer L;Butterworth, Adam Stuart;Dupuis, Josée;Easton, Douglas Frederick;Eeles, Rosalind A;Erdmann, Jeanette;Franks, Paul W;Frayling, Timothy M;Hansen, Torben;Howson, Joanna McCammond;Jørgensen, Torben;Kooner, Jaspal;Laakso, Markku;Langenberg, Claudia;McCarthy, Mark I;Pankow, James S;Pedersen, Oluf;Riboli, Elio;Rotter, Jerome I;Saleheen, Danish;Samani, Nilesh J;Schunkert, Heribert;Vollenweider, Peter;O’Rahilly, Stephen;Deloukas, Panos;Danesh, John;Goodarzi, Mark O;Kathiresan, Sekar;Meigs, James B;Ehm, Margaret G;Wareham, Nicholas J;Waterworth, Nicholas John
Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic therapies by predicting...