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Milne, Roger L.;Burwinkel, Barbara;Michailidou, Kyriaki;Arias-Perez, Jose-Ignacio;Zamora, M. Pilar;Menéndez-Rodríguez, Primitiva;Hardisson, David;Mendiola, Marta;González-Neira, Anna;Pita, Guillermo;Alonso, M. Rosario;Dennis, Joe;Wang, Qin;Bolla, Manjeet K.;Swerdlow, Anthony;Ashworth, Alan;Orr, Nick;Schoemaker, Minouk;Ko, Yon-Dschun;Brauch, Hiltrud;Hamann, Ute;Andrulis, Irene L.;Knight, Julia A.;Glendon, Gord;Tchatchou, Sandrine;Matsuo, Keitaro;Ito, Hidemi;Iwata, Hiroji;Tajima, Kazuo;Li, Jingmei;Brand, Judith S.;Brenner, Hermann;Dieffenbach, Aida Karina;Arndt, Volker;Stegmaier, Christa;Lambrechts, Diether;Peuteman, Gilian;Christiaens, Marie-Rose;Smeets, Ann;Jakubowska, Anna;Lubinski, Jan;Jaworska-Bieniek, Katarzyna;Durda, Katazyna;Hartman, Mikael;Hui, Miao;Yen Lim, Wei;Wan Chan, Ching;Marme, Federick;Yang, Rongxi;Bugert, Peter;Lindblom, Annika;Margolin, Sara;García-Closas, Montserrat;Chanock, Stephen J.;Lissowska, Jolanta;Figueroa, Jonine D.;Bojesen, Stig E.;Nordestgaard, Børge G.;Flyger, Henrik;Hooning, Maartje J.;Kriege, Mieke;van den Ouweland, Ans M.W.;Koppert, Linetta B.;Fletcher, Olivia;Johnson, Nichola;dos-Santos-Silva, Isabel;Peto, Julian;Zheng, Wei;Deming-Halverson, Sandra;Shrubsole, Martha J.;Long, Jirong;Chang-Claude, Jenny;Rudolph, Anja;Seibold, Petra;Flesch-Janys, Dieter;Winqvist, Robert;Pylkäs, Katri;Jukkola-Vuorinen, Arja;Grip, Mervi;Cox, Angela;Cross, Simon S.;Reed, Malcolm W.R.;Schmidt, Marjanka K.;Broeks, Annegien;Cornelissen, Sten;Braaf, Linde;Kang, Daehee;Choi, Ji-Yeob;Park, Sue K.;Noh, Dong-Young;Simard, Jacques;Dumont, Martine;Goldberg, Mark S.;Labrèche, France;Fasching, Peter A.;Hein, Alexander;Ekici, Arif B.;Beckmann, Matthias W.;Radice, Paolo;Peterlongo, Paolo;Azzollini, Jacopo;Barile, Monica;Sawyer, Elinor;Tomlinson, Ian;Kerin, Michael;Miller, Nicola;Hopper, John L.;Schmidt, Daniel F.;Makalic, Enes;Southey, Melissa C.;Hwang Teo, Soo;Har Yip, Cheng;Sivanandan, Kavitta;Tay, Wan-Ting;Shen, Chen-Yang;Hsiung, Chia-Ni;Yu, Jyh-Cherng;Hou, Ming-Feng;Guénel, Pascal;Truong, Therese;Sanchez, Marie;Mulot, Claire;Blot, William;Cai, Qiuyin;Nevanlinna, Heli;Muranen, Taru A.;Aittomäki, Kristiina;Blomqvist, Carl;Wu, Anna H.;Tseng, Chiu-Chen;Van Den Berg, David;Stram, Daniel O.;Bogdanova, Natalia;Dörk, Thilo;Muir, Kenneth;Lophatananon, Artitaya;Stewart-Brown, Sarah;Siriwanarangsan, Pornthep;Mannermaa, Arto;Kataja, Vesa;Kosma, Veli-Matti;Hartikainen, Jaana M.;Shu, Xiao-Ou;Lu, Wei;Gao, Yu-Tang;Zhang, Ben;Couch, Fergus J.;Toland, Amanda E.;Yannoukakos, Drakoulis;Sangrajrang, Suleeporn;McKay, James;Wang, Xianshu;Olson, Janet E.;Vachon, Celine;Purrington, Kristen;Severi, Gianluca;Baglietto, Laura;Haiman, Christopher A.;Henderson, Brian E.;Schumacher, Fredrick;Le Marchand, Loic;Devilee, Peter;Tollenaar, Robert A.E.M.;Seynaeve, Caroline;Czene, Kamila;Eriksson, Mikael;Humphreys, Keith;Darabi, Hatef;Ahmed, Shahana;Shah, Mitul;Pharoah, Paul D.P.;Hall, Per;Giles, Graham G.;Benítez, Javier;Dunning, Alison M.;Chenevix-Trench, Georgia;Easton, Douglas F.;Berchuck, Andrew;Eeles, Rosalind A.;Olama, Ali Amin Al;Kote-Jarai, Zsofia;Benlloch, Sara;Antoniou, Antonis;McGuffog, Lesley;Offit, Ken;Lee, Andrew;Dicks, Ed;Luccarini, Craig;Tessier, Daniel C.;Bacot, Francois;Vincent, Daniel;LaBoissière, Sylvie;Robidoux, Frederic;Nielsen, Sune F.;Cunningham, Julie M.;Windebank, Sharon A.;Hilker, Christopher A.;Meyer, Jeffrey;Angelakos, Maggie;Maskiell, Judi;Schoot, Ellen van der;Rutgers, Emiel;Verhoef, Senno;Hogervorst, Frans;Boonyawongviroj, Prat;Siriwanarungsan, Pornthep;Schrauder, Michael;Rübner, Matthias;Oeser, Sonja;Landrith, Silke;Williams, Eileen;Ryder-Mills, Elaine;Sargus, Kara;McInerney, Niall;Colleran, Gabrielle;Rowan, Andrew;Jones, Angela;Sohn, Christof;Schneeweiß, Andeas;Bugert, Peter;Álvarez, Núria;Lacey, James;Wang, Sophia;Ma, Huiyan;Lu, Yani;Deapen, Dennis;Pinder, Rich;Lee, Eunjung;Schumacher, Fred;Horn-Ross, Pam;Reynolds, Peggy;Nelson, David;Ziegler, Hartwig;Wolf, Sonja;Hermann, Volker;Lo, Wing-Yee;Justenhoven, Christina;Baisch, Christian;Fischer, Hans-Peter;Brüning, Thomas;Pesch, Beate;Rabstein, Sylvia;Lotz, Anne;Harth, Volker;Heikkinen, Tuomas;Erkkilä, Irja;Aaltonen, Kirsimari;Smitten, Karl von;Antonenkova, Natalia;Hillemanns, Peter;Christiansen, Hans;Myöhänen, Eija;Kemiläinen, Helena;Thorne, Heather;Niedermayr, Eveline;Bowtell, D;Chenevix-Trench, G;deFazio, A;Gertig, D;Green, A;Webb, P;Green, A.;Parsons, P.;Hayward, N.;Webb, P.;Whiteman, D.;Fung, Annie;Yashiki, June;Peuteman, Gilian;Smeets, Dominiek;Brussel, Thomas Van;Corthouts, Kathleen;Obi, Nadia;Heinz, Judith;Behrens, Sabine;Eilber, Ursula;Celik, Muhabbet;Olchers, Til;Manoukian, Siranoush;Peissel, Bernard;Scuvera, Giulietta;Zaffaroni, Daniela;Bonanni, Bernardo;Feroce, Irene;Maniscalco, Angela;Rossi, Alessandra;Bernard, Loris;Tranchant, Martine;Valois, Marie-France;Turgeon, Annie;Heguy, Lea;Sze Yee, Phuah;Kang, Peter;Nee, Kang In;Mariapun, Shivaani;Sook-Yee, Yoon;Lee, Daphne;Ching, Teh Yew;Taib, Nur Aishah Mohd;Otsukka, Meeri;Mononen, Kari;Selander, Teresa;Weerasooriya, Nayana;staff, OFBCR;Krol-Warmerdam, E.;Molenaar, J.;Blom, J.;Brinton, Louise;Szeszenia-Dabrowska, Neonila;Peplonska, Beata;Zatonski, Witold;Chao, Pei;Stagner, Michael;Bos, Petra;Blom, Jannet;Crepin, Ellen;Nieuwlaat, Anja;Heemskerk, Annette;Higham, Sue;Cross, Simon;Cramp, Helen;Connley, Dan;Balasubramanian, Sabapathy;Brock, Ian;Luccarini, Craig;Conroy, Don;Baynes, Caroline;Chua, Kimberley
Candidate variant association studies have been largely unsuccessful in identifying common breast cancer susceptibility variants, although most studies have been underpowered to detect associations of a realistic magnitude. We assessed 41 common non-...
Southey, Melissa C;Goldgar, David E;Winqvist, Robert;Pylkäs, Katri;Couch, Fergus;Tischkowitz, Marc;Foulkes, William D;Dennis, Joe;Michailidou, Kyriaki;van Rensburg, Elizabeth J;Heikkinen, Tuomas;Nevanlinna, Heli;Hopper, John L;Dörk, Thilo;Claes, Kathleen BM;Reis-Filho, Jorge;Teo, Zhi Ling;Radice, Paolo;Catucci, Irene;Peterlongo, Paolo;Tsimiklis, Helen;Odefrey, Fabrice A;Dowty, James G;Schmidt, Marjanka K;Broeks, Annegien;Hogervorst, Frans B;Verhoef, Senno;Carpenter, Jane;Clarke, Christine;Scott, Rodney J;Fasching, Peter A;Haeberle, Lothar;Ekici, Arif B;Beckmann, Matthias W;Peto, Julian;dos-Santos-Silva, Isabel;Fletcher, Olivia;Johnson, Nichola;Bolla, Manjeet K;Sawyer, Elinor J;Tomlinson, Ian;Kerin, Michael J;Miller, Nicola;Marme, Federik;Burwinkel, Barbara;Yang, Rongxi;Guénel, Pascal;Truong, Thérèse;Menegaux, Florence;Sanchez, Marie;Bojesen, Stig;Nielsen, Sune F;Flyger, Henrik;Benitez, Javier;Zamora, M Pilar;Perez, Jose Ignacio Arias;Menéndez, Primitiva;Anton-Culver, Hoda;Neuhausen, Susan;Ziogas, Argyrios;Clarke, Christina A;Brenner, Hermann;Arndt, Volker;Stegmaier, Christa;Brauch, Hiltrud;Brüning, Thomas;Ko, Yon-Dschun;Muranen, Taru A;Aittomäki, Kristiina;Blomqvist, Carl;Bogdanova, Natalia V;Antonenkova, Natalia N;Lindblom, Annika;Margolin, Sara;Mannermaa, Arto;Kataja, Vesa;Kosma, Veli-Matti;Hartikainen, Jaana M;Spurdle, Amanda B;Investigators, kConFab;Wauters, Els;Smeets, Dominiek;Beuselinck, Benoit;Floris, Giuseppe;Chang-Claude, Jenny;Rudolph, Anja;Seibold, Petra;Flesch-Janys, Dieter;Olson, Janet E;Vachon, Celine;Pankratz, Vernon S;McLean, Catriona;Haiman, Christopher A;Henderson, Brian E;Schumacher, Fredrick;Le Marchand, Loic;Kristensen, Vessela;Alnæs, Grethe Grenaker;Zheng, Wei;Hunter, David J;Lindstrom, Sara;Hankinson, Susan E;Kraft, Peter;Andrulis, Irene;Knight, Julia A;Glendon, Gord;Mulligan, Anna Marie;Jukkola-Vuorinen, Arja;Grip, Mervi;Kauppila, Saila;Devilee, Peter;Tollenaar, Robert A E M;Seynaeve, Caroline;Hollestelle, Antoinette;Garcia-Closas, Montserrat;Figueroa, Jonine;Chanock, Stephen J;Lissowska, Jolanta;Czene, Kamila;Darabi, Hatef;Eriksson, Mikael;Eccles, Diana M;Rafiq, Sajjad;Tapper, William J;Gerty, Sue M;Hooning, Maartje J;Martens, John W M;Collée, J Margriet;Tilanus-Linthorst, Madeleine;Hall, Per;Li, Jingmei;Brand, Judith S;Humphreys, Keith;Cox, Angela;Reed, Malcolm W R;Luccarini, Craig;Baynes, Caroline;Dunning, Alison M;Hamann, Ute;Torres, Diana;Ulmer, Hans Ulrich;Rüdiger, Thomas;Jakubowska, Anna;Lubinski, Jan;Jaworska, Katarzyna;Durda, Katarzyna;Slager, Susan;Toland, Amanda E;Ambrosone, Christine B;Yannoukakos, Drakoulis;Swerdlow, Anthony;Ashworth, Alan;Orr, Nick;Jones, Michael;González-Neira, Anna;Pita, Guillermo;Alonso, M Rosario;Álvarez, Nuria;Herrero, Daniel;Tessier, Daniel C;Vincent, Daniel;Bacot, Francois;Simard, Jacques;Dumont, Martine;Soucy, Penny;Eeles, Rosalind;Muir, Kenneth;Wiklund, Fredrik;Gronberg, Henrik;Schleutker, Johanna;Nordestgaard, Børge G;Weischer, Maren;Travis, Ruth C;Neal, David;Donovan, Jenny L;Hamdy, Freddie C;Khaw, Kay-Tee;Stanford, Janet L;Blot, William J;Thibodeau, Stephen;Schaid, Daniel J;Kelley, Joseph L;Maier, Christiane;Kibel, Adam S;Cybulski, Cezary;Cannon-Albright, Lisa;Butterbach, Katja;Park, Jong;Kaneva, Radka;Batra, Jyotsna;Teixeira, Manuel R;Kote-Jarai, Zsofia;Olama, Ali Amin Al;Benlloch, Sara;Renner, Stefan P;Hartmann, Arndt;Hein, Alexander;Ruebner, Matthias;Lambrechts, Diether;Van Nieuwenhuysen, Els;Vergote, Ignace;Lambretchs, Sandrina;Doherty, Jennifer A;Rossing, Mary Anne;Nickels, Stefan;Eilber, Ursula;Wang-Gohrke, Shan;Odunsi, Kunle;Sucheston-Campbell, Lara E;Friel, Grace;Lurie, Galina;Killeen, Jeffrey L;Wilkens, Lynne R;Goodman, Marc T;Runnebaum, Ingo;Hillemanns, Peter A;Pelttari, Liisa M;Butzow, Ralf;Modugno, Francesmary;Edwards, Robert P;Ness, Roberta B;Moysich, Kirsten B;du Bois, Andreas;Heitz, Florian;Harter, Philipp;Kommoss, Stefan;Karlan, Beth Y;Walsh, Christine;Lester, Jenny;Jensen, Allan;Kjaer, Susanne Krüger;Høgdall, Estrid;Peissel, Bernard;Bonanni, Bernardo;Bernard, Loris;Goode, Ellen L;Fridley, Brooke L;Vierkant, Robert A;Cunningham, Julie M;Larson, Melissa C;Fogarty, Zachary C;Kalli, Kimberly R;Liang, Dong;Lu, Karen H;Hildebrandt, Michelle A T;Wu, Xifeng;Levine, Douglas A;Dao, Fanny;Bisogna, Maria;Berchuck, Andrew;Iversen, Edwin S;Marks, Jeffrey R;Akushevich, Lucy;Cramer, Daniel W;Schildkraut, Joellen;Terry, Kathryn L;Poole, Elizabeth M;Stampfer, Meir;Tworoger, Shelley S;Bandera, Elisa V;Orlow, Irene;Olson, Sara H;Bjorge, Line;Salvesen, Helga B;van Altena, Anne M;Aben, Katja K H;Kiemeney, Lambertus A;Massuger, Leon F A G;Pejovic, Tanja;Bean, Yukie;Brooks-Wilson, Angela;Kelemen, Linda E;Cook, Linda S;Le, Nhu D;Górski, Bohdan;Gronwald, Jacek;Menkiszak, Janusz;Høgdall, Claus K;Lundvall, Lene;Nedergaard, Lotte;Engelholm, Svend Aage;Dicks, Ed;Tyrer, Jonathan;Campbell, Ian;McNeish, Iain;Paul, James;Siddiqui, Nadeem;Glasspool, Rosalind;Whittemore, Alice S;Rothstein, Joseph H;McGuire, Valerie;Sieh, Weiva;Cai, Hui;Shu, Xiao-Ou;Teten, Rachel T;Sutphen, Rebecca;McLaughlin, John R;Narod, Steven A;Phelan, Catherine M;Monteiro, Alvaro N;Fenstermacher, David;Lin, Hui-Yi;Permuth, Jennifer B;Sellers, Thomas A;Chen, Y Ann;Tsai, Ya-Yu;Chen, Zhihua;Gentry-Maharaj, Aleksandra;Gayther, Simon A;Ramus, Susan J;Menon, Usha;Wu, Anna H;Pearce, Celeste L;Van Den Berg, David;Pike, Malcolm C;Dansonka-Mieszkowska, Agnieszka;Plisiecka-Halasa, Joanna;Moes-Sosnowska, Joanna;Kupryjanczyk, Jolanta;Pharoah, Paul DP;Song, Honglin;Winship, Ingrid;Chenevix-Trench, Georgia;Giles, Graham G;Tavtigian, Sean V;Easton, Doug F;Milne, Roger L;,
Background The rarity of mutations in PALB2, CHEK2 and ATM make it difficult to estimate precisely associated cancer risks. Population-based family studies have provided evidence that at least some of these mutations are associated with breast cancer...
Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series,...
To integrate the mapping of ERG alterations with the collection of expression microarray (EMA) data, as previous EMA analyses have failed to consider the genetic heterogeneity and complex patterns of ERG alteration frequently found in cancerous prost...
Several susceptibility loci for classical Hodgkin lymphoma have been reported. However, much of the heritable risk is unknown. Here, we perform a meta-analysis of two existing genome-wide association studies, a new genome-wide association study, and ...
Schumacher, Fredrick R.;Al Olama, Ali Amin;Berndt, Sonja I.;Benlloch, Sara;Ahmed, Mahbubl;Saunders, Edward J.;Dadaev, Tokhir;Leongamornlert, Daniel;Anokian, Ezequiel;Cieza-Borrella, Clara;Goh, Chee;Brook, Mark N.;Sheng, Xin;Fachal, Laura;Dennis, Joe;Tyrer, Jonathan;Muir, Kenneth;Lophatananon, Artitaya;Stevens, Victoria L.;Gapstur, Susan M.;Carter, Brian D.;Tangen, Catherine M.;Goodman, Phyllis J.;Thompson, Ian M.;Batra, Jyotsna;Chambers, Suzanne;Moya, Leire;Clements, Judith;Horvath, Lisa;Tilley, Wayne;Risbridger, Gail P.;Gronberg, Henrik;Aly, Markus;Nordström, Tobias;Pharoah, Paul;Pashayan, Nora;Schleutker, Johanna;Tammela, Teuvo L.J.;Sipeky, Csilla;Auvinen, Anssi;Albanes, Demetrius;Weinstein, Stephanie;Wolk, Alicja;Håkansson, Niclas;West, Catharine M.L.;Dunning, Alison M.;Burnet, Neil;Mucci, Lorelei A.;Giovannucci, Edward;Andriole, Gerald L.;Cussenot, Olivier;Cancel-Tassin, Géraldine;Koutros, Stella;Beane Freeman, Laura E.;Sorensen, Karina Dalsgaard;Orntoft, Torben Falck;Borre, Michael;Maehle, Lovise;Grindedal, Eli Marie;Neal, David E.;Donovan, Jenny L.;Hamdy, Freddie C.;Martin, Richard M.;Travis, Ruth C.;Key, Tim J.;Hamilton, Robert J.;Fleshner, Neil E.;Finelli, Antonio;Ingles, Sue Ann;Stern, Mariana C.;Rosenstein, Barry S.;Kerns, Sarah L.;Ostrer, Harry;Lu, Yong Jie;Zhang, Hong Wei;Feng, Ninghan;Mao, Xueying;Guo, Xin;Wang, Guomin;Sun, Zan;Giles, Graham G.;Southey, Melissa C.;MacInnis, Robert J.;FitzGerald, Liesel M.;Kibel, Adam S.;Drake, Bettina F.;Vega, Ana;Gómez-Caamaño, Antonio;Szulkin, Robert;Eklund, Martin;Kogevinas, Manolis;Llorca, Javier;Castaño-Vinyals, Gemma;Penney, Kathryn L.;Stampfer, Meir;Park, Jong Y.;Sellers, Thomas A.;Lin, Hui Yi;Stanford, Janet L.;Cybulski, Cezary;Wokolorczyk, Dominika;Lubinski, Jan;Ostrander, Elaine A.;Geybels, Milan S.;Nordestgaard, Børge G.;Nielsen, Sune F.;Weischer, Maren;Bisbjerg, Rasmus;Røder, Martin Andreas;Iversen, Peter;Brenner, Hermann;Cuk, Katarina;Holleczek, Bernd;Maier, Christiane;Luedeke, Manuel;Schnoeller, Thomas;Kim, Jeri;Logothetis, Christopher J.;John, Esther M.;Teixeira, Manuel R.;Paulo, Paula;Cardoso, Marta;Neuhausen, Susan L.;Steele, Linda;Ding, Yuan Chun;de Ruyck, Kim;de Meerleer, Gert;Ost, Piet;Razack, Azad;Lim, Jasmine;Teo, Soo Hwang;Lin, Daniel W.;Newcomb, Lisa F.;Lessel, Davor;Gamulin, Marija;Kulis, Tomislav;Kaneva, Radka;Usmani, Nawaid;Singhal, Sandeep;Slavov, Chavdar;Mitev, Vanio;Parliament, Matthew;Claessens, Frank;Joniau, Steven;van Den Broeck, Thomas;Larkin, Samantha;Townsend, Paul A.;Aukim-Hastie, Claire;Dominguez, Manuela Gago;Castelao, Jose Esteban;Martinez, Maria Elena;Roobol, Monique J.;Jenster, Guido;van Schaik, Ron H.N.;Menegaux, Florence;Truong, Thérèse;Koudou, Yves Akoli;Xu, Jianfeng;Khaw, Kay Tee;Cannon-Albright, Lisa;Pandha, Hardev;Michael, Agnieszka;Thibodeau, Stephen N.;McDonnell, Shannon K.;Schaid, Daniel J.;Lindstrom, Sara;Turman, Constance;Ma, Jing;Hunter, David J.;Riboli, Elio;Siddiq, Afshan;Canzian, Federico;Kolonel, Laurence N.;Le Marchand, Loic;Hoover, Robert N.;Machiela, Mitchell J.;Cui, Zuxi;Kraft, Peter;Amos, Christopher I.;Conti, David V.;Easton, Douglas F.;Wiklund, Fredrik;Chanock, Stephen J.;Henderson, Brian E.;Kote-Jarai, Zsofia;Haiman, Christopher A.;Eeles, Rosalind A.
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data from a custom high-density array of 46,939 PrCa cases and 27,910 controls...
Circulating insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are associated with prostate cancer. Using genetic variants as instruments for IGF peptides, we investigated whether these associations are likely to be causal. We ide...