ARTICLES
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Document(s)
Title
We developed comprehensive models to determine risk of Barrett's esophagus (BE) or esophageal adenocarcinoma (EAC) based on genetic and non-genetic factors.We used pooled data from 3288 patients with BE, 2511 patients with EAC, and 2177 individuals w...
Circular RNAs (circRNAs) are a class of RNAs that is under increasing scrutiny, although their functional roles are debated. We analyzed RNA-seq data of 348 primary breast cancers and developed a method to identify circRNAs that does not rely on unma...
BACKGROUND:
Circular RNAs (circRNAs) are a class of RNAs that is under increasing scrutiny, although their functional roles are debated. We analyzed RNA-seq data of 348 primary breast cancers and developed a method to identify circRNAs that does not rely on unma...
The rates and routes of lethal systemic spread in breast cancer are poorly understood due to the lack of molecularly characterized cohorts with long-term, detailed follow-up. Long-term follow-up is especially essential for ER-positive (ER+) breast ca...
Background: Adjuvant trastuzumab significantly improves outcomes in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer (EBC). The standard duration is 12 months but shorter treatment could provide similar efficacy whilst red...
Circular RNAs (circRNAs) are a class of RNAs that is under increasing scrutiny, although their functional roles are debated. We analyzed RNA-seq data of 348 primary breast cancers and developed a method to identify circRNAs that does not rely on unma...
Objective Oesophageal adenocarcinoma (OA) incidence has risen sharply in Western countries over recent decades. Local and systemic inflammation is considered an important contributor to OA pathogenesis. Established risk factors for OA and its precurs...