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Wessel, Jennifer;Chu, Audrey Y;Willems, Sara Marie;Wang, Shuai;Yaghootkar, Hanieh;Brody, Jennifer A;Dauriz, Marco;Hivert, Marie-France;Raghavan, Sridharan;Lipovich, Leonard;Hidalgo, Bertha;Fox, Keolu;Huffman, Jennifer E;An, Ping;Lu, Yingchang;Rasmussen-Torvik, Laura J;Grarup, Niels;Ehm, Margaret G;Li, Li;Baldridge, Abigail S;Stancakova, Alena;Abrol, Ravinder;Besse, Celine;Boland, Anne;Bork-Jensen, Jette;Fornage, Myriam;Freitag, Daniel Franz;Garcia, Melissa E;Guo, Xiuqing;Hara, Kazuo;Isaacs, Aaron;Jakobsdottir, Johanna;Lange, Leslie A;Layton, Jill C;Li, Man;Hua, Zhao Jing;Meidtner, Karina;Morrison, Alanna C;Nalls, Mike A;Peters, Marjolein J;Sabater-Lleal, Maria;Schurmann, Claudia;Silveira, Angela;Smith, Albert V;Southam, Lorraine;Stoiber, Marcus H;Strawbridge, Rona J;Taylor, Kent D;Varga, Tibor V;Allin, Kristine H;Amin, Najaf;Aponte, Jennifer L;Aung, Tin;Barbieri, Caterina;Bihlmeyer, Nathan A;Boehnke, Michael;Bombieri, Cristina;Bowden, Donald W;Burns, Sean M;Chen, Yuning;Chen, Yii-DerI;Cheng, Ching-Yu;Correa, Adolfo;Czajkowski, Jacek;Dehghan, Abbas;Ehret, Georg B;Eiriksdottir, Gudny;Escher, Stefan A;Farmaki, Aliki-Eleni;Franberg, Mattias;Gambaro, Giovanni;Giulianini, Franco;Goddard, William A;Goel, Anuj;Gottesman, Omri;Grove, Megan L;Gustafsson, Stefan;Hai, Yang;Hallmans, Goran;Heo, Jiyoung;Hoffmann, Per;Ikram, Mohammad K;Jensen, Richard A;Jorgensen, Marit E;Jorgensen, Torben;Karaleftheri, Maria;Khor, Chiea C;Kirkpatrick, Andrea;Kraja, Aldi T;Kuusisto, Johanna;Lange, Ethan M;Lee, IT;Lee, Wen-Jane;Leong, Aaron;Liao, Jiemin;Liu, Chunyu;Liu, Yongmei;Lindgren, Cecilia M;Linneberg, Allan;Malerba, Giovanni;Mamakou, Vasiliki;Marouli, Eirini;Maruthur, Nisa M;Matchan, Angela;McKean-Cowdin, Roberta;McLeod, Olga;Metcalf, Ginger A;Mohlke, Karen L;Muzny, Donna M;Ntalla, Ioanna;Palmer, Nicholette D;Pasko, Dorota;Peter, Andreas;Rayner, Nigel W;Renstrom, Frida;Rice, Ken;Sala, Cinzia F;Sennblad, Bengt;Serafetinidis, Ioannis;Smith, Jennifer A;Soranzo, Nicole;Speliotes, Elizabeth K;Stahl, Eli A;Stirrups, Kathleen Elizabeth;Tentolouris, Nikos;Thanopoulou, Anastasia;Torres, Mina;Traglia, Michela;Tsafantakis, Emmanouil;Javad, Sundas;Yanek, Lisa R;Zengini, Eleni;Becker, Diane M;Bis, Joshua C;Brown, James B;Cupples, L Adrienne;Hansen, Torben;Ingelsson, Erik;Karter, Andrew J;Lorenzo, Carlos;Mathias, Rasika A;Norris, Jill M;Peloso, Gina M;Sheu, Wayne H-H;Toniolo, Daniela;Vaidya, Dhananjay;Varma, Rohit;Wagenknecht, Lynne E;Boeing, Heiner;Bottinger, Erwin P;Dedoussis, George;Deloukas, Panos;Ferrannini, Ele;Franco, Oscar H;Franks, Paul W;Gibbs, Richard A;Gudnason, Vilmundur;Hamsten, Anders;Harris, Tamara B;Hattersley, Andrew T;Hayward, Caroline;Hofman, Albert;Jansson, Jan-Hakan;Langenberg, Claudia;Launer, Lenore J;Levy, Daniel;Oostra, Ben A;O'Donnell, Christopher J;O'Rahilly, Stephen;Padmanabhan, Sandosh;Pankow, James S;Polasek, Ozren;Province, Michael A;Rich, Stephen S;Ridker, Paul M;Rudan, Igor;Schulze, Matthias B;Smith, Blair H;Uitterlinden, Andre G;Walker, Mark;Watkins, Hugh;Wong, Tien Y;Zeggini, Eleftheria;EPIC-InterAct, Consortium;Laakso, Markku;Borecki, Ingrid B;Chasman, Daniel I;Pedersen, Oluf;Psaty, Bruce M;Tai, E Shyong;Duijn, Cornelia M van;Wareham, Nicholas John;Waterworth, Dawn M;Boerwinkle, Eric;Kao, WH Linda;Florez, Jose C;Loos, Ruth;Wilson, James G;Frayling, Timothy M;Siscovick, David S;Dupuis, Josee;Rotter, Jerome I;Meigs, James B;Scott, Robert;Goodarzi, Mark O
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals and in 16,491 T2D cases and 81...
Scott, Robert A.;Freitag, Daniel F.;Li, Li;Chu, Audrey Y.;Surendran, Praveen;Young, Robin;Grarup, Niels;Stancáková, Alena;Chen, Yuning;Varga, Tibor V.;Yaghootkar, Hanieh;Luan, Jian'an;Zhao, Jing Hua;Willems, Sara M.;Wessel, Jennifer;Wang, Shuai;Maruthur, Nisa;Michailidou, Kyriaki;Pirie, Ailith;Van Der Lee, Sven J.;Gillson, Christopher;Al Olama, Ali Amin;Amouyel, Philippe;Arriola, Larraitz;Arveiler, Dominique;Aviles-Olmos, Iciar;Balkau, Beverley;Barricarte, Aurelio;Barroso, Inês;Garcia, Sara Benlloch;Bis, Joshua C.;Blankenberg, Stefan;Boehnke, Michael;Boeing, Heiner;Boerwinkle, Eric;Borecki, Ingrid B.;Bork-Jensen, Jette;Bowden, Sarah;Caldas, Carlos;Caslake, Muriel;Cupples, L. Adrienne;Cruchaga, Carlos;Czajkowski, Jacek;Den Hoed, Marcel;Dunn, Janet A.;Earl, Helena M.;Ehret, Georg B.;Ferrannini, Ele;Ferrieres, Jean;Foltynie, Thomas;Ford, Ian;Forouhi, Nita G.;Gianfagna, Francesco;Gonzalez, Carlos;Grioni, Sara;Hiller, Louise;Jansson, Jan Håkan;Jørgensen, Marit E.;Jukema, J. Wouter;Kaaks, Rudolf;Kee, Frank;Kerrison, Nicola D.;Key, Timothy J.;Kontto, Jukka;Kote-Jarai, Zsofia;Kraja, Aldi T.;Kuulasmaa, Kari;Kuusisto, Johanna;Linneberg, Allan;Liu, Chunyu;Marenne, Gaëlle;Mohlke, Karen L.;Morris, Andrew P.;Muir, Kenneth;Müller-Nurasyid, Martina;Munroe, Patricia B.;Navarro, Carmen;Nielsen, Sune F.;Nilsson, Peter M.;Nordestgaard, Børge G.;Packard, Chris J.;Palli, Domenico;Panico, Salvatore;Peloso, Gina M.;Perola, Markus;Peters, Annette;Poole, Christopher J.;Quirós, J. Ramón;Rolandsson, Olov;Sacerdote, Carlotta;Salomaa, Veikko;Sánchez, María José;Sattar, Naveed;Sharp, Stephen J.;Sims, Rebecca;Slimani, Nadia;Smith, Jennifer A.;Thompson, Deborah J.;Trompet, Stella;Tumino, Rosario;Van Der A, Daphne L.;Van Der Schouw, Yvonne T.;Virtamo, Jarmo;Walker, Mark;Walter, Klaudia;Abraham, Jean E.;Amundadottir, Laufey T.;Butterworth, Adam S.;Aponte, Jennifer L.;Dupuis, Josée;Easton, Douglas F.;Eeles, Rosalind A.;Erdmann, Jeanette;Franks, Paul W.;Frayling, Timothy M.;Hansen, Torben;Howson, Joanna M M;Jørgensen, Torben;Kooner, Jaspal;Laakso, Markku;McCarthy, Mark I.;Pankow, James S.;Pedersen, Oluf;Riboli, Elio;Rotter, Jerome I.;Saleheen, Danish;Samani, Nilesh J.;Schunkert, Heribert;Vollenweider, Peter;O'Rahilly, Stephen;Deloukas, Panos;Danesh, John;Goodarzi, Mark O.;Kathiresan, Sekar;Meigs, James B.;Ehm, Margaret G.;Wareham, Nicholas J.;Waterworth, Dawn M.
Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic therapies by predicting...
Wessel, Jennifer;Chu, Audrey Y;Willems, Sara M;Wang, Shuai;Yaghootkar, Hanieh;Brody, Jennifer A;Dauriz, Marco;Hivert, Marie-France;Raghavan, Sridharan;Lipovich, Leonard;Hidalgo, Bertha;Fox, Keolu;Huffman, Jennifer E;An, Ping;Lu, Yingchang;Rasmussen-Torvik, Laura J;Grarup, Niels;Ehm, Margaret G;Li, Li;Baldridge, Abigail S;Stančáková, Alena;Abrol, Ravinder;Besse, Céline;Boland, Anne;Bork-Jensen, Jette;Fornage, Myriam;Freitag, Daniel F;Garcia, Melissa E;Guo, Xiuqing;Hara, Kazuo;Isaacs, Aaron;Jakobsdottir, Johanna;Lange, Leslie A;Layton, Jill C;Li, Man;Hua Zhao, Jing;Meidtner, Karina;Morrison, Alanna C;Nalls, Mike A;Peters, Marjolein J;Sabater-Lleal, Maria;Schurmann, Claudia;Silveira, Angela;Smith, Albert V;Southam, Lorraine;Stoiber, Marcus H;Strawbridge, Rona J;Taylor, Kent D;V Varga, Tibor;Allin, Kristine H;Amin, Najaf;Aponte, Jennifer L;Aung, Tin;Barbieri, Caterina;Bihlmeyer, Nathan A;Boehnke, Michael;Bombieri, Cristina;Bowden, Donald W;Burns, Sean M;Chen, Yuning;Chen, Yii-DerI;Cheng, Ching-Yu;Correa, Adolfo;Czajkowski, Jacek;Dehghan, Abbas;Ehret, Georg B;Eiriksdottir, Gudny;Escher, Stefan A;Farmaki, Aliki-Eleni;Frånberg, Mattias;Gambaro, Giovanni;Giulianini, Franco;Goddard, William A;Goel, Anuj;Gottesman, Omri;Grove, Megan L;Gustafsson, Stefan;Hai, Yang;Hallmans, Göran;Heo, Jiyoung;Hoffmann, Per;Ikram, Mohammad K;Jensen, Richard A;Jørgensen, Marit E;Jørgensen, Torben;Karaleftheri, Maria;Khor, Chiea C;Kirkpatrick, Andrea;Kraja, Aldi T;Kuusisto, Johanna;Lange, Ethan M;Lee, I T;Lee, Wen-Jane;Leong, Aaron;Liao, Jiemin;Liu, Chunyu;Liu, Yongmei;Lindgren, Cecilia M;Linneberg, Allan;Malerba, Giovanni;Mamakou, Vasiliki;Marouli, Eirini;Maruthur, Nisa M;Matchan, Angela;McKean-Cowdin, Roberta;McLeod, Olga;Metcalf, Ginger A;Mohlke, Karen L;Muzny, Donna M;Ntalla, Ioanna;Palmer, Nicholette D;Pasko, Dorota;Peter, Andreas;Rayner, Nigel W;Renström, Frida;Rice, Ken;Sala, Cinzia F;Sennblad, Bengt;Serafetinidis, Ioannis;Smith, Jennifer A;Soranzo, Nicole;Speliotes, Elizabeth K;Stahl, Eli A;Stirrups, Kathleen;Tentolouris, Nikos;Thanopoulou, Anastasia;Torres, Mina;Traglia, Michela;Tsafantakis, Emmanouil;Javad, Sundas;Yanek, Lisa R;Zengini, Eleni;Becker, Diane M;Bis, Joshua C;Brown, James B;Adrienne Cupples, L;Hansen, Torben;Ingelsson, Erik;Karter, Andrew J;Lorenzo, Carlos;Mathias, Rasika A;Norris, Jill M;Peloso, Gina M;Sheu, Wayne H-H;Toniolo, Daniela;Vaidya, Dhananjay;Varma, Rohit;Wagenknecht, Lynne E;Boeing, Heiner;Bottinger, Erwin P;Dedoussis, George;Deloukas, Panos;Ferrannini, Ele;Franco, Oscar H;Franks, Paul;Gibbs, Richard A;Gudnason, Vilmundur;Hamsten, Anders;Harris, Tamara B;Hattersley, Andrew T;Hayward, Caroline;Hofman, Albert;Jansson, Jan-Håkan;Langenberg, Claudia;Launer, Lenore J;Levy, Daniel;Oostra, Ben A;O'Donnell, Christopher J;O'Rahilly, Stephen;Padmanabhan, Sandosh;Pankow, James S;Polasek, Ozren;Province, Michael A;Rich, Stephen S;Ridker, Paul M;Rudan, Igor;Schulze, Matthias B;Smith, Blair H;Uitterlinden, André G;Walker, Mark;Watkins, Hugh;Wong, Tien Y;Zeggini, Eleftheria;Laakso, Markku;Borecki, Ingrid B;Chasman, Daniel I;Pedersen, Oluf;Psaty, Bruce M;Shyong Tai, E;van Duijn, Cornelia M;Wareham, Nicholas J;Waterworth, Dawn M;Boerwinkle, Eric;Linda Kao, W H;Florez, Jose C;Loos, Ruth J F;Wilson, James G;Frayling, Timothy M;Siscovick, David S;Dupuis, Josée;Rotter, Jerome I;Meigs, James B;Scott, Robert A;Goodarzi, Mark O
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals and in 16,491 T2D cases and 81...
Wessel, Jennifer;Chu, Audrey Y;Willems, Sara M;Wang, Shuai;Yaghootkar, Hanieh;Brody, Jennifer A;Dauriz, Marco;Hivert, Marie-France;Raghavan, Sridharan;Lipovich, Leonard;Hidalgo, Bertha;Fox, Keolu;Huffman, Jennifer E;An, Ping;Lu, Yingchang;Rasmussen-Torvik, Laura J;Grarup, Niels;Ehm, Margaret G;Li, Li;Baldridge, Abigail S;Stančáková, Alena;Abrol, Ravinder;Besse, Céline;Boland, Anne;Bork-Jensen, Jette;Fornage, Myriam;Freitag, Daniel F;Garcia, Melissa E;Guo, Xiuqing;Hara, Kazuo;Isaacs, Aaron;Jakobsdottir, Johanna;Lange, Leslie A;Layton, Jill C;Li, Man;Hua Zhao, Jing;Meidtner, Karina;Morrison, Alanna C;Nalls, Mike A;Peters, Marjolein J;Sabater-Lleal, Maria;Schurmann, Claudia;Silveira, Angela;Smith, Albert V;Southam, Lorraine;Stoiber, Marcus H;Strawbridge, Rona J;Taylor, Kent D;V Varga, Tibor;Allin, Kristine H;Amin, Najaf;Aponte, Jennifer L;Aung, Tin;Barbieri, Caterina;Bihlmeyer, Nathan A;Boehnke, Michael;Bombieri, Cristina;Bowden, Donald W;Burns, Sean M;Chen, Yuning;Chen, Yii-DerI;Cheng, Ching-Yu;Correa, Adolfo;Czajkowski, Jacek;Dehghan, Abbas;Ehret, Georg B;Eiriksdottir, Gudny;Escher, Stefan A;Farmaki, Aliki-Eleni;Frånberg, Mattias;Gambaro, Giovanni;Giulianini, Franco;Goddard, William A;Goel, Anuj;Gottesman, Omri;Grove, Megan L;Gustafsson, Stefan;Hai, Yang;Hallmans, Göran;Heo, Jiyoung;Hoffmann, Per;Ikram, Mohammad K;Jensen, Richard A;Jørgensen, Marit E;Jørgensen, Torben;Karaleftheri, Maria;Khor, Chiea C;Kirkpatrick, Andrea;Kraja, Aldi T;Kuusisto, Johanna;Lange, Ethan M;Lee, I T;Lee, Wen-Jane;Leong, Aaron;Liao, Jiemin;Liu, Chunyu;Liu, Yongmei;Lindgren, Cecilia M;Linneberg, Allan;Malerba, Giovanni;Mamakou, Vasiliki;Marouli, Eirini;Maruthur, Nisa M;Matchan, Angela;McKean-Cowdin, Roberta;McLeod, Olga;Metcalf, Ginger A;Mohlke, Karen L;Muzny, Donna M;Ntalla, Ioanna;Palmer, Nicholette D;Pasko, Dorota;Peter, Andreas;Rayner, Nigel W;Renström, Frida;Rice, Ken;Sala, Cinzia F;Sennblad, Bengt;Serafetinidis, Ioannis;Smith, Jennifer A;Soranzo, Nicole;Speliotes, Elizabeth K;Stahl, Eli A;Stirrups, Kathleen;Tentolouris, Nikos;Thanopoulou, Anastasia;Torres, Mina;Traglia, Michela;Tsafantakis, Emmanouil;Javad, Sundas;Yanek, Lisa R;Zengini, Eleni;Becker, Diane M;Bis, Joshua C;Brown, James B;Adrienne Cupples, L;Hansen, Torben;Ingelsson, Erik;Karter, Andrew J;Lorenzo, Carlos;Mathias, Rasika A;Norris, Jill M;Peloso, Gina M;Sheu, Wayne H-H;Toniolo, Daniela;Vaidya, Dhananjay;Varma, Rohit;Wagenknecht, Lynne E;Boeing, Heiner;Bottinger, Erwin P;Dedoussis, George;Deloukas, Panos;Ferrannini, Ele;Franco, Oscar H;Franks, Paul;Gibbs, Richard A;Gudnason, Vilmundur;Hamsten, Anders;Harris, Tamara B;Hattersley, Andrew T;Hayward, Caroline;Hofman, Albert;Jansson, Jan-Håkan;Langenberg, Claudia;Launer, Lenore J;Levy, Daniel;Oostra, Ben A;O'Donnell, Christopher J;O'Rahilly, Stephen;Padmanabhan, Sandosh;Pankow, James S;Polasek, Ozren;Province, Michael A;Rich, Stephen S;Ridker, Paul M;Rudan, Igor;Schulze, Matthias B;Smith, Blair H;Uitterlinden, André G;Walker, Mark;Watkins, Hugh;Wong, Tien Y;Zeggini, Eleftheria;Laakso, Markku;Borecki, Ingrid B;Chasman, Daniel I;Pedersen, Oluf;Psaty, Bruce M;Shyong Tai, E;van Duijn, Cornelia M;Wareham, Nicholas J;Waterworth, Dawn M;Boerwinkle, Eric;Linda Kao, W H;Florez, Jose C;Loos, Ruth J F;Wilson, James G;Frayling, Timothy M;Siscovick, David S;Dupuis, Josée;Rotter, Jerome I;Meigs, James B;Scott, Robert A;Goodarzi, Mark O
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals and in 16,491 T2D cases and 81...
Wessel, Jennifer;Chu, Audrey Y.;Willems, Sara M.;Wang, Shuai;Yaghootkar, Hanieh;Brody, Jennifer A.;Dauriz, Marco;Hivert, Marie-France;Raghavan, Sridharan;Lipovich, Leonard;Hidalgo, Bertha;Fox, Keolu;Huffman, Jennifer E.;An, Ping;Lu, Yingchang;Rasmussen-Torvik, Laura J.;Grarup, Niels;Ehm, Margaret G.;Li, Li;Baldridge, Abigail S.;Stancakova, Alena;Abrol, Ravinder;Besse, Celine;Boland, Anne;Bork-Jensen, Jette;Fornage, Myriam;Freitag, Daniel F.;Garcia, Melissa E.;Guo, Xiuqing;Hara, Kazuo;Isaacs, Aaron;Jakobsdottir, Johanna;Lange, Leslie A.;Layton, Jill C.;Li, Man;Zhao, Jing Hua;Meidtner, Karina;Morrison, Alanna C.;Nalls, Mike A.;Peters, Marjolein J.;Sabater-Lleal, Maria;Schurmann, Claudia;Silveira, Angela;Smith, Albert V.;Southam, Lorraine;Stoiber, Marcus H.;Strawbridge, Rona J.;Taylor, Kent D.;Varga, Tibor V.;Allin, Kristine H.;Amin, Najaf;Aponte, Jennifer L.;Aung, Tin;Barbieri, Caterina;Bihlmeyer, Nathan A.;Boehnke, Michael;Bombieri, Cristina;Bowden, Donald W.;Burns, Sean M.;Chen, Yuning;Chen, Yii-Deri;Cheng, Ching-Yu;Correa, Adolfo;Czajkowski, Jacek;Dehghan, Abbas;Ehret, Georg B.;Eiriksdottir, Gudny;Andersson Escher, Stefan;Farmaki, Aliki-Eleni;Franberg, Mattias;Gambaro, Giovanni;Giulianini, Franco;Goddard, William A., III;Goel, Anuj;Gottesman, Omri;Grove, Megan L.;Gustafsson, Stefan;Hai, Yang;Hallmans, Goeran;Heo, Jiyoung;Hoffmann, Per;Ikram, Mohammad K.;Jensen, Richard A.;Jorgensen, Marit E.;Jorgensen, Torben;Karaleftheri, Maria;Khor, Chiea C.;Kirkpatrick, Andrea;Kraja, Aldi T.;Kuusisto, Johanna;Lange, Ethan M.;Lee, I. T.;Lee, Wen-Jane;Leong, Aaron;Liao, Jiemin;Liu, Chunyu;Liu, Yongmei;Lindgren, Cecilia M.;Linneberg, Allan;Malerba, Giovanni;Mamakou, Vasiliki;Marouli, Eirini;Maruthur, Nisa M.;Matchan, Angela;McKean-Cowdin, Roberta;McLeod, Olga;Metcalf, Ginger A.;Mohlke, Karen L.;Muzny, Donna M.;Ntalla, Ioanna;Palmer, Nicholette D.;Pasko, Dorota;Peter, Andreas;Rayner, Nigel W.;Renstroem, Frida;Rice, Ken;Sala, Cinzia F.;Sennblad, Bengt;Serafetinidis, Ioannis;Smith, Jennifer A.;Soranzo, Nicole;Speliotes, Elizabeth K.;Stahl, Eli A.;Stirrups, Kathleen;Tentolouris, Nikos;Thanopoulou, Anastasia;Torres, Mina;Traglia, Michela;Tsafantakis, Emmanouil;Javad, Sundas;Yanek, Lisa R.;Zengini, Eleni;Becker, Diane M.;Bis, Joshua C.;Brown, James B.;Cupples, L. Adrienne;Hansen, Torben;Ingelsson, Erik;Karter, Andrew J.;Lorenzo, Carlos;Mathias, Rasika A.;Norris, Jill M.;Peloso, Gina M.;Sheu, Wayne H. -H.;Toniolo, Daniela;Vaidya, Dhananjay;Varma, Rohit;Wagenknecht, Lynne E.;Boeing, Heiner;Bottinger, Erwin P.;Dedoussis, George;Deloukas, Panos;Ferrannini, Ele;Franco, Oscar H.;Franks, Paul W.;Gibbs, Richard A.;Gudnason, Vilmundur;Hamsten, Anders;Harris, Tamara B.;Hattersley, Andrew T.;Hayward, Caroline;Hofman, Albert;Jansson, Jan-Håkan;Langenberg, Claudia;Launer, Lenore J.;Levy, Daniel;Oostra, Ben A.;O'Donnell, Christopher J.;O'Rahilly, Stephen;Padmanabhan, Sandosh;Pankow, James S.;Polasek, Ozren;Province, Michael A.;Rich, Stephen S.;Ridker, Paul M.;Rudan, Igor;Schulze, Matthias B.;Smith, Blair H.;Uitterlinden, Andre G.;Walker, Mark;Watkins, Hugh;Wong, Tien Y.;Zeggini, Eleftheria;Laakso, Markku;Borecki, Ingrid B.;Chasman, Daniel I.;Pedersen, Oluf;Psaty, Bruce M.;Tai, E. Shyong;van Duijn, Cornelia M.;Wareham, Nicholas J.;Waterworth, Dawn M.;Boerwinkle, Eric;Kao, W. H. Linda;Florez, Jose C.;Loos, Ruth J. F.;Wilson, James G.;Frayling, Timothy M.;Siscovick, David S.;Dupuis, Josee;Rotter, Jerome I.;Meigs, James B.;Scott, Robert A.;Goodarzi, Mark O.;Sharp, Stephen J.;Forouhi, Nita G.;Kerrison, Nicola D.;Lucarelli, Debora M. E.;Sims, Matt;Barroso, Ines;McCarthy, Mark I.;Arriola, Larraitz;Balkau, Beverley;Barricarte, Aurelio;Gonzalez, Carlos;Grioni, Sara;Kaaks, Rudolf;Key, Timothy J.;Navarro, Carmen;Nilsson, Peter M.;Overvad, Kim;Palli, Domenico;Panico, Salvatore;Quiros, J. Ramon;Rolandsson, Olov;Sacerdote, Carlotta;Sanchez, Maria-Jose;Slimani, Nadia;Tjonneland, Anne;Tumino, Rosario;van der A, Daphne L.;van der Schouw, Yvonne T.;Riboli, Elio
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals and in 16,491 T2D cases and 81...
Wessel, Jennifer;Chu, Audrey Y;Willems, Sara M;Wang, Shuai;Yaghootkar, Hanieh;Brody, Jennifer A;Dauriz, Marco;Hivert, Marie-France;Raghavan, Sridharan;Lipovich, Leonard;Hidalgo, Bertha;Fox, Keolu;Huffman, Jennifer E;An, Ping;Lu, Yingchang;Rasmussen-Torvik, Laura J;Grarup, Niels;Ehm, Margaret G;Li, Li;Baldridge, Abigail S;Stančáková, Alena;Abrol, Ravinder;Besse, Céline;Boland, Anne;Bork-Jensen, Jette;Fornage, Myriam;Freitag, Daniel F;Garcia, Melissa E;Guo, Xiuqing;Hara, Kazuo;Isaacs, Aaron;Jakobsdottir, Johanna;Lange, Leslie A;Layton, Jill C;Li, Man;Hua Zhao, Jing;Meidtner, Karina;Morrison, Alanna C;Nalls, Mike A;Peters, Marjolein J;Sabater-Lleal, Maria;Schurmann, Claudia;Silveira, Angela;Smith, Albert V;Southam, Lorraine;Stoiber, Marcus H;Strawbridge, Rona J.;Taylor, Kent D;Varga, Tibor V;Allin, Kristine H;Amin, Najaf;Aponte, Jennifer L;Aung, Tin;Barbieri, Caterina;Bihlmeyer, Nathan A;Boehnke, Michael;Bombieri, Cristina;Bowden, Donald W;Burns, Sean M;Chen, Yuning;Chen, Yii-DerI;Cheng, Ching-Yu;Correa, Adolfo;Czajkowski, Jacek;Dehghan, Abbas;Ehret, Georg B;Eiriksdottir, Gudny;Escher, Stefan A;Farmaki, Aliki-Eleni;Frånberg, Mattias;Gambaro, Giovanni;Giulianini, Franco;Goddard, William A;Goel, Anuj;Gottesman, Omri;Grove, Megan L;Gustafsson, Stefan;Hai, Yang;Hallmans, Göran;Heo, Jiyoung;Hoffmann, Per;Ikram, Mohammad K;Jensen, Richard A;Jørgensen, Marit E;Jørgensen, Torben;Karaleftheri, Maria;Khor, Chiea C;Kirkpatrick, Andrea;Kraja, Aldi T;Kuusisto, Johanna;Lange, Ethan M;Lee, I T;Lee, Wen-Jane;Leong, Aaron;Liao, Jiemin;Liu, Chunyu;Liu, Yongmei;Lindgren, Cecilia M;Linneberg, Allan;Malerba, Giovanni;Mamakou, Vasiliki;Marouli, Eirini;Maruthur, Nisa M;Matchan, Angela;McKean-Cowdin, Roberta;McLeod, Olga;Metcalf, Ginger A;Mohlke, Karen L;Muzny, Donna M;Ntalla, Ioanna;Palmer, Nicholette D;Pasko, Dorota;Peter, Andreas;Rayner, Nigel W;Renström, Frida;Rice, Ken;Sala, Cinzia F;Sennblad, Bengt;Serafetinidis, Ioannis;Smith, Jennifer A;Soranzo, Nicole;Speliotes, Elizabeth K;Stahl, Eli A;Stirrups, Kathleen;Tentolouris, Nikos;Thanopoulou, Anastasia;Torres, Mina;Traglia, Michela;Tsafantakis, Emmanouil;Javad, Sundas;Yanek, Lisa R;Zengini, Eleni;Becker, Diane M;Bis, Joshua C;Brown, James B;Adrienne Cupples, L;Hansen, Torben;Ingelsson, Erik;Karter, Andrew J;Lorenzo, Carlos;Mathias, Rasika A;Norris, Jill M;Peloso, Gina M;Sheu, Wayne H.-H.;Toniolo, Daniela;Vaidya, Dhananjay;Varma, Rohit;Wagenknecht, Lynne E;Boeing, Heiner;Bottinger, Erwin P;Dedoussis, George;Deloukas, Panos;Ferrannini, Ele;Franco, Oscar H;Franks, Paul W;Gibbs, Richard A;Gudnason, Vilmundur;Hamsten, Anders;Harris, Tamara B;Hattersley, Andrew T;Hayward, Caroline;Hofman, Albert;Jansson, Jan-Håkan;Langenberg, Claudia;Launer, Lenore J;Levy, Daniel;Oostra, Ben A;O’Donnell, Christopher J;O’Rahilly, Stephen;Padmanabhan, Sandosh;Pankow, James S;Polasek, Ozren;Province, Michael A;Rich, Stephen S;Ridker, Paul M;Rudan, Igor;Schulze, Matthias B;Smith, Blair H;Uitterlinden, André G;Walker, Mark;Watkins, Hugh;Wong, Tien Y;Zeggini, Eleftheria;Sharp, Stephen J;Forouhi, Nita G;Kerrison, Nicola D;Lucarelli, Debora ME;Sims, Matt;Barroso, Inês;McCarthy, Mark I;Arriola, Larraitz;Balkau, Beverley;Barricarte, Aurelio;Gonzalez, Carlos;Grioni, Sara;Kaaks, Rudolf;Key, Timothy J;Navarro, Carmen;Nilsson, Peter M;Overvad, Kim;Palli, Domenico;Panico, Salvatore;Quirós, J. Ramón;Rolandsson, Olov;Sacerdote, Carlotta;Sánchez, María–José;Slimani, Nadia;Tjonneland, Anne;Tumino, Rosario;van der A, Daphne L;van der Schouw, Yvonne T;Riboli, Elio;Laakso, Markku;Borecki, Ingrid B;Chasman, Daniel I;Pedersen, Oluf;Psaty, Bruce M;Shyong Tai, E;van Duijn, Cornelia M;Wareham, Nicholas J;Waterworth, Dawn M;Boerwinkle, Eric;Linda Kao, W H;Florez, Jose C;Loos, Ruth J.F.;Wilson, James G;Frayling, Timothy M;Siscovick, David S;Dupuis, Josée;Rotter, Jerome I;Meigs, James B;Scott, Robert A;Goodarzi, Mark O
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals and in 16,491 T2D cases and 81...
Scott, Robert A.;Freitag, Daniel F.;Li, Li;Chu, Audrey Y.;Surendran, Praveen;Young, Robin;Grarup, Niels;Stancáková, Alena;Chen, Yuning;Varga, Tibor V.;Yaghootkar, Hanieh;Luan, Jian'an;Zhao, Jing Hua;Willems, Sara M.;Wessel, Jennifer;Wang, Shuai;Maruthur, Nisa;Michailidou, Kyriaki;Pirie, Ailith;van der Lee, Sven J.;Gillson, Christopher;Al Olama, Ali Amin;Amouyel, Philippe;Arriola, Larraitz;Arveiler, Dominique;Aviles-Olmos, Iciar;Balkau, Beverley;Barricarte, Aurelio;Barroso, Inês;Garcia, Sara Benlloch;Bis, Joshua C.;Blankenberg, Stefan;Boehnke, Michael;Boeing, Heiner;Boerwinkle, Eric;Borecki, Ingrid B.;Bork-Jensen, Jette;Bowden, Sarah;Caldas, Carlos;Caslake, Muriel;Cupples, L Adrienne;Cruchaga, Carlos;Czajkowski, Jacek;den Hoed, Marcel;Dunn, Janet A.;Earl, Helena M.;Ehret, Georg B.;Ferrannini, Ele;Ferrieres, Jean;Foltynie, Thomas;Ford, Ian;Forouhi, Nita G.;Gianfagna, Francesco;Gonzalez, Carlos;Grioni, Sara;Hiller, Louise;Jansson, Jan-Håkan;Jørgensen, Marit E.;Jukema, J Wouter;Kaaks, Rudolf;Kee, Frank;Kerrison, Nicola D.;Key, Timothy J.;Kontto, Jukka;Kote-Jarai, Zsofia;Kraja, Aldi T.;Kuulasmaa, Kari;Kuusisto, Johanna;Linneberg, Allan;Liu, Chunyu;Marenne, Gaëlle;Mohlke, Karen L.;Morris, Andrew P.;Muir, Kenneth;Müller-Nurasyid, Martina;Munroe, Patricia B.;Navarro, Carmen;Nielsen, Sune F.;Nilsson, Peter M.;Nordestgaard, Børge G.;Packard, Chris J.;Palli, Domenico;Panico, Salvatore;Peloso, Gina M.;Perola, Markus;Peters, Annette;Poole, Christopher J.;Quirós, J. Ramón;Rolandsson, Olov;Sacerdote, Carlotta;Salomaa, Veikko;Sánchez, María-José;Sattar, Naveed;Sharp, Stephen J.;Sims, Rebecca;Slimani, Nadia;Smith, Jennifer A.;Thompson, Deborah J.;Trompet, Stella;Tumino, Rosario;van der A, Daphne L.;van der Schouw, Yvonne T.;Virtamo, Jarmo;Walker, Mark;Walter, Klaudia;Abraham, Jean E.;Amundadottir, Laufey T.;Aponte, Jennifer L.;Butterworth, Adam S.;Dupuis, Josée;Easton, Douglas F.;Eeles, Rosalind A.;Erdmann, Jeanette;Franks, Paul W.;Frayling, Timothy M.;Hansen, Torben;Howson, Joanna M.M.;Jørgensen, Torben;Kooner, Jaspal;Laakso, Markku;Langenberg, Claudia;McCarthy, Mark I.;Pankow, James S.;Pedersen, Oluf;Riboli, Elio;Rotter, Jerome I.;Saleheen, Danish;Samani, Nilesh J.;Schunkert, Heribert;Vollenweider, Peter;O'Rahilly, Stephen;Deloukas, Panos;Danesh, John;Goodarzi, Mark O.;Kathiresan, Sekar;Meigs, James B.;Ehm, Margaret G.;Wareham, Nicholas J.;Waterworth, Dawn M.
Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic therapies by predicting...
Scott, Robert A.;Freitag, Daniel F.;Li, Li;Chu, Audrey Y.;Surendran, Praveen;Young, Robin;Grarup, Niels;Stanc�kov�, Alena;Chen, Yuning;Varga, Tibor V.;Yaghootkar, Hanieh;Luan, Jian'an;Zhao, Jing Hua;Willems, Sara M.;Wessel, Jennifer;Wang, Shuai;Maruthur, Nisa;Michailidou, Kyriaki;Pirie, Ailith;Van Der Lee, Sven J.;Gillson, Christopher;Al Olama, Ali Amin;Amouyel, Philippe;Arriola, Larraitz;Arveiler, Dominique;Aviles-Olmos, Iciar;Balkau, Beverley;Barricarte, Aurelio;Barroso, In�s;Garcia, Sara Benlloch;Bis, Joshua C.;Blankenberg, Stefan;Boehnke, Michael;Boeing, Heiner;Boerwinkle, Eric;Borecki, Ingrid B.;Bork-Jensen, Jette;Bowden, Sarah;Caldas, Carlos;Caslake, Muriel;Cupples, L. Adrienne;Cruchaga, Carlos;Czajkowski, Jacek;Den Hoed, Marcel;Dunn, Janet A.;Earl, Helena M.;Ehret, Georg B.;Ferrannini, Ele;Ferrieres, Jean;Foltynie, Thomas;Ford, Ian;Forouhi, Nita G.;Gianfagna, Francesco;Gonzalez, Carlos;Grioni, Sara;Hiller, Louise;Jansson, Jan-H�kan;J�rgensen, Marit E.;Jukema, J. Wouter;Kaaks, Rudolf;Kee, Frank;Kerrison, Nicola D.;Key, Timothy J.;Kontto, Jukka;Kote-Jarai, Zsofia;Kraja, Aldi T.;Kuulasmaa, Kari;Kuusisto, Johanna;Linneberg, Allan;Liu, Chunyu;Marenne, Ga�lle;Mohlke, Karen L;Morris, Andrew P.;Muir, Kenneth;M�ller-Nurasyid, Martina;Munroe, Patricia B.;Navarro, Carmen;Nielsen, Sune F.;Nilsson, Peter M.;Nordestgaard, B�rge G.;Packard, Chris J.;Palli, Domenico;Panico, Salvatore;Peloso, Gina M.;Perola, Markus;Peters, Annette;Poole, Christopher J.;Quir�s, J. Ram�n;Rolandsson, Olov;Sacerdote, Carlotta;Salomaa, Veikko;S�nchez, Mar�a-Jos�;Sattar, Naveed;Sharp, Stephen J.;Sims, Rebecca;Slimani, Nadia;Smith, Jennifer A.;Thompson, Deborah J.;Trompet, Stella;Tumino, Rosario;Van Der A, Daphne L.;Van Der Schouw, Yvonne T.;Virtamo, Jarmo;Walker, Mark;Walter, Klaudia;Abraham, Jean E.;Amundadottir, Laufey T.;Butterworth, Adam S.;Aponte, Jennifer L;Dupuis, Jos�e;Easton, Douglas F.;Eeles, Rosalind A.;Erdmann, Jeanette;Franks, Paul W.;Frayling, Timothy M.;Hansen, Torben;Howson, Joanna M.M.;J�rgensen, Torben;Kooner, Jaspal;Laakso, Markku;McCarthy, Mark I.;Pankow, James S.;Pedersen, Oluf;Riboli, Elio;Rotter, Jerome I.;Saleheen, Danish;Samani, Nilesh J.;Schunkert, Heribert;Vollenweider, Peter;O'Rahilly, Stephen;Deloukas, Panos;Danesh, John;Goodarzi, Mark O.;Kathiresan, Sekar;Meigs, James B.;Ehm, Margaret G.;Wareham, Nicholas J.;Waterworth, Dawn M.
Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic therapies by predicting...
Wessel, Jennifer;Chu, Audrey Y;Willems, Sara M;Wang, Shuai;Yaghootkar, Hanieh;Brody, Jennifer A;Dauriz, Marco;Hivert, Marie-France;Raghavan, Sridharan;Lipovich, Leonard;Hidalgo, Bertha;Fox, Keolu;Huffman, Jennifer E;An, Ping;Lu, Yingchang;Rasmussen-Torvik, Laura J;Grarup, Niels;Ehm, Margaret G;Li, Li;Baldridge, Abigail S;Stančáková, Alena;Abrol, Ravinder;Besse, Céline;Boland, Anne;Bork-Jensen, Jette;Fornage, Myriam;Freitag, Daniel F;Garcia, Melissa E;Guo, Xiuqing;Hara, Kazuo;Isaacs, Aaron;Jakobsdottir, Johanna;Lange, Leslie A;Layton, Jill C;Li, Man;Hua Zhao, Jing;Meidtner, Karina;Morrison, Alanna C;Nalls, Mike A;Peters, Marjolein J;Sabater-Lleal, Maria;Schurmann, Claudia;Silveira, Angela;Smith, Albert V;Southam, Lorraine;Stoiber, Marcus H;Strawbridge, Rona J;Taylor, Kent D;Varga, Tibor V;Allin, Kristine H;Amin, Najaf;Aponte, Jennifer L;Aung, Tin;Barbieri, Caterina;Bihlmeyer, Nathan A;Boehnke, Michael;Bombieri, Cristina;Bowden, Donald W;Burns, Sean M;Chen, Yuning;Chen, Yii-Deri;Cheng, Ching-Yu;Correa, Adolfo;Czajkowski, Jacek;Dehghan, Abbas;Ehret, Georg B;Eiriksdottir, Gudny;Escher, Stefan A;Farmaki, Aliki-Eleni;Frånberg, Mattias;Gambaro, Giovanni;Giulianini, Franco;Goddard, William A;Goel, Anuj;Gottesman, Omri;Grove, Megan L;Gustafsson, Stefan;Hai, Yang;Hallmans, Göran;Heo, Jiyoung;Hoffmann, Per;Ikram, Mohammad K;Jensen, Richard A;Jørgensen, Marit E;Jørgensen, Torben;Karaleftheri, Maria;Khor, Chiea C;Kirkpatrick, Andrea;Kraja, Aldi T;Kuusisto, Johanna;Lange, Ethan M;Lee, I. T.;Lee, Wen-Jane;Leong, Aaron;Liao, Jiemin;Liu, Chunyu;Liu, Yongmei;Lindgren, Cecilia M;Linneberg, Allan;Malerba, Giovanni;Mamakou, Vasiliki;Marouli, Eirini;Maruthur, Nisa M;Matchan, Angela;McKean-Cowdin, Roberta;McLeod, Olga;Metcalf, Ginger A;Mohlke, Karen L;Muzny, Donna M;Ntalla, Ioanna;Palmer, Nicholette D;Pasko, Dorota;Peter, Andreas;Rayner, Nigel W;Renström, Frida;Rice, Ken;Sala, Cinzia F;Sennblad, Bengt;Serafetinidis, Ioannis;Smith, Jennifer A;Soranzo, Nicole;Speliotes, Elizabeth K;Stahl, Eli A;Stirrups, Kathleen;Tentolouris, Nikos;Thanopoulou, Anastasia;Torres, Mina;Traglia, Michela;Tsafantakis, Emmanouil;Javad, Sundas;Yanek, Lisa R;Zengini, Eleni;Becker, Diane M;Bis, Joshua C;Brown, James B;Adrienne Cupples, L.;Hansen, Torben;Ingelsson, Erik;Karter, Andrew J;Lorenzo, Carlos;Mathias, Rasika A;Norris, Jill M;Peloso, Gina M;Sheu, Wayne H.-H.;Toniolo, Daniela;Vaidya, Dhananjay;Varma, Rohit;Wagenknecht, Lynne E;Boeing, Heiner;Bottinger, Erwin P;Dedoussis, George;Deloukas, Panos;Ferrannini, Ele;Franco, Oscar H;Franks, Paul W;Gibbs, Richard A;Gudnason, Vilmundur;Hamsten, Anders;Harris, Tamara B;Hattersley, Andrew T;Hayward, Caroline;Hofman, Albert;Jansson, Jan-Håkan;Langenberg, Claudia;Launer, Lenore J;Levy, Daniel;Oostra, Ben A;O'Donnell, Christopher J;O'Rahilly, Stephen;Padmanabhan, Sandosh;Pankow, James S;Polasek, Ozren;Province, Michael A;Rich, Stephen S;Ridker, Paul M;Rudan, Igor;Schulze, Matthias B;Smith, Blair H;Uitterlinden, André G;Walker, Mark;Watkins, Hugh;Wong, Tien Y;Zeggini, Eleftheria;Laakso, Markku;Borecki, Ingrid B;Chasman, Daniel I;Pedersen, Oluf;Psaty, Bruce M;Shyong Tai, E.;Van Duijn, Cornelia M;Wareham, Nicholas J;Waterworth, Dawn M;Boerwinkle, Eric;Linda Kao, W. H.;Florez, Jose C;Loos, Ruth J.F.;Wilson, James G;Frayling, Timothy M;Siscovick, David S;Dupuis, Josée;Rotter, Jerome I;Meigs, James B;Scott, Robert A.;Goodarzi, Mark O.
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants on the HumanExome BeadChip in 60,564 non-diabetic individuals and in 16,491 T2D cases and 81...