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Wolpin, Brian M;Rizzato, Cosmeri;Kraft, Peter;Kooperberg, Charles;Petersen, Gloria M;Wang, Zhaoming;Arslan, Alan A;Beane-Freeman, Laura;Bracci, Paige M;Buring, Julie;Canzian, Federico;Duell, Eric J;Gallinger, Steven;Giles, Graham G;Goodman, Gary E;Goodman, Phyllis J;Jacobs, Eric J;Kamineni, Aruna;Klein, Alison P;Kolonel, Laurence N;Kulke, Matthew H;Li, Donghui;Malats, Núria;Olson, Sara H;Risch, Harvey A;Sesso, Howard D;Visvanathan, Kala;White, Emily;Zheng, Wei;Abnet, Christian C;Albanes, Demetrius;Andreotti, Gabriella;Austin, Melissa A;Barfield, Richard;Basso, Daniela;Berndt, Sonja I;Boutron-Ruault, Marie-Christine;Brotzman, Michelle;Büchler, Markus W;Bueno-de-Mesquita, H Bas;Bugert, Peter;Burdette, Laurie;Campa, Daniele;Caporaso, Neil E;Capurso, Gabriele;Chung, Charles;Cotterchio, Michelle;Costello, Eithne;Elena, Joanne;Funel, Niccola;Gaziano, J Michael;Giese, Nathalia A;Giovannucci, Edward L;Goggins, Michael;Gorman, Megan J;Gross, Myron;Haiman, Christopher A;Hassan, Manal;Helzlsouer, Kathy J;Henderson, Brian E;Holly, Elizabeth A;Hu, Nan;Hunter, David J;Innocenti, Federico;Jenab, Mazda;Kaaks, Rudolf;Key, Timothy J;Khaw, Kay-Tee;Klein, Eric A;Kogevinas, Manolis;Krogh, Vittorio;Kupcinskas, Juozas;Kurtz, Robert C;LaCroix, Andrea;Landi, Maria T;Landi, Stefano;Le Marchand, Loic;Mambrini, Andrea;Mannisto, Satu;Milne, Roger L;Nakamura, Yusuke;Oberg, Ann L;Owzar, Kouros;Patel, Alpa V;Peeters, Petra HM;Peters, Ulrike;Pezzilli, Raffaele;Piepoli, Ada;Porta, Miquel;Real, Francisco X;Riboli, Elio;Rothman, Nathaniel;Scarpa, Aldo;Shu, Xiao-Ou;Silverman, Debra T;Soucek, Pavel;Sund, Malin;Talar-Wojnarowska, Renata;Taylor, Philip R;Theodoropoulos, George E;Thornquist, Mark;Tjønneland, Anne;Tobias, Geoffrey S;Trichopoulos, Dimitrios;Vodicka, Pavel;Wactawski-Wende, Jean;Wentzensen, Nicolas;Wu, Chen;Yu, Herbert;Yu, Kai;Zeleniuch-Jacquotte, Anne;Hoover, Robert;Hartge, Patricia;Fuchs, Charles;Chanock, Stephen J;Stolzenberg-Solomon, Rachael S;Amundadottir, Laufey T
We performed a multistage genome-wide association study including 7,683 individuals with pancreatic cancer and 14,397 controls of European descent. Four new loci reached genome-wide significance: rs6971499 at 7q32.3 (LINC-PINT, per-allele odds ratio ...
Pancreatic cancer is the fourth leading cause of cancer death in the developed world. Both inherited high-penetrance mutations in BRCA2 (ref. 2), ATM, PALB2 (ref. 4), BRCA1 (ref. 5), STK11 (ref. 6), CDKN2A and mismatch-repair genes and low-penetrance...
Machiela, Mitchell J;Zhou, Weiyin;Sampson, Joshua N;Dean, Michael C;Jacobs, Kevin B;Black, Amanda;Brinton, Louise A;Chang, I-Shou;Chen, Chu;Chen, Constance;Chen, Kexin;Cook, Linda S;Crous Bou, Marta;De Vivo, Immaculata;Doherty, Jennifer;Friedenreich, Christine M;Gaudet, Mia M;Haiman, Christopher A;Hankinson, Susan E;Hartge, Patricia;Henderson, Brian E;Hong, Yun-Chul;Hosgood, H Dean;Hsiung, Chao A;Hu, Wei;Hunter, David J;Jessop, Lea;Kim, Hee Nam;Kim, Yeul Hong;Kim, Young Tae;Klein, Robert;Kraft, Peter;Lan, Qing;Lin, Dongxin;Liu, Jianjun;Le Marchand, Loic;Liang, Xiaolin;Lissowska, Jolanta;Lu, Lingeng;Magliocco, Anthony M;Matsuo, Keitaro;Olson, Sara H;Orlow, Irene;Park, Jae Yong;Pooler, Loreall;Prescott, Jennifer;Rastogi, Radhai;Risch, Harvey A;Schumacher, Fredrick;Seow, Adeline;Setiawan, Veronica Wendy;Shen, Hongbing;Sheng, Xin;Shin, Min-Ho;Shu, Xiao-Ou;VanDen Berg, David;Wang, Jiu-Cun;Wentzensen, Nicolas;Wong, Maria Pik;Wu, Chen;Wu, Tangchun;Wu, Yi-Long;Xia, Lucy;Yang, Hannah P;Yang, Pan-Chyr;Zheng, Wei;Zhou, Baosen;Abnet, Christian C;Albanes, Demetrius;Aldrich, Melinda C;Amos, Christopher;Amundadottir, Laufey T;Berndt, Sonja I;Blot, William J;Bock, Cathryn H;Bracci, Paige M;Burdett, Laurie;Buring, Julie E;Butler, Mary A;Carreón, Tania;Chatterjee, Nilanjan;Chung, Charles C;Cook, Michael B;Cullen, Michael;Davis, Faith G;Ding, Ti;Duell, Eric J;Epstein, Caroline G;Fan, Jin-Hu;Figueroa, Jonine D;Fraumeni, Joseph F;Freedman, Neal D;Fuchs, Charles S;Gao, Yu-Tang;Gapstur, Susan M;Patiño-Garcia, Ana;Garcia-Closas, Montserrat;Gaziano, J Michael;Giles, Graham G;Gillanders, Elizabeth M;Giovannucci, Edward L;Goldin, Lynn;Goldstein, Alisa M;Greene, Mark H;Hallmans, Goran;Harris, Curtis C;Henriksson, Roger;Holly, Elizabeth A;Hoover, Robert N;Hu, Nan;Hutchinson, Amy;Jenab, Mazda;Johansen, Christoffer;Khaw, Kay-Tee;Koh, Woon-Puay;Kolonel, Laurence N;Kooperberg, Charles;Krogh, Vittorio;Kurtz, Robert C;LaCroix, Andrea;Landgren, Annelie;Landi, Maria Teresa;Li, Donghui;Liao, Linda M;Malats, Nuria;McGlynn, Katherine A;McNeill, Lorna H;McWilliams, Robert R;Melin, Beatrice S;Mirabello, Lisa;Peplonska, Beata;Peters, Ulrike;Petersen, Gloria M;Prokunina-Olsson, Ludmila;Purdue, Mark;Qiao, You-Lin;Rabe, Kari G;Rajaraman, Preetha;Real, Francisco X;Riboli, Elio;Rodríguez-Santiago, Benjamín;Rothman, Nathaniel;Ruder, Avima M;Savage, Sharon A;Schwartz, Ann G;Schwartz, Kendra L;Sesso, Howard D;Severi, Gianluca;Silverman, Debra T;Spitz, Margaret R;Stevens, Victoria L;Stolzenberg-Solomon, Rachael;Stram, Daniel;Tang, Ze-Zhong;Taylor, Philip R;Teras, Lauren R;Tobias, Geoffrey S;Viswanathan, Kala;Wacholder, Sholom;Wang, Zhaoming;Weinstein, Stephanie J;Wheeler, William;White, Emily;Wiencke, John K;Wolpin, Brian M;Wu, Xifeng;Wunder, Jay S;Yu, Kai;Zanetti, Krista A;Zeleniuch-Jacquotte, Anne;Ziegler, Regina G;de Andrade, Mariza;Barnes, Kathleen C;Beaty, Terri H;Bierut, Laura J;Desch, Karl C;Doheny, Kimberly F;Feenstra, Bjarke;Ginsburg, David;Heit, John A;Kang, Jae H;Laurie, Cecilia A;Li, Jun Z;Lowe, William L;Marazita, Mary L;Melbye, Mads;Mirel, Daniel B;Murray, Jeffrey C;Nelson, Sarah C;Pasquale, Louis R;Rice, Kenneth;Wiggs, Janey L;Wise, Anastasia;Tucker, Margaret;Pérez-Jurado, Luis A;Laurie, Cathy C;Caporaso, Neil E;Yeager, Meredith;Chanock, Stephen J
Analyses of genome-wide association study (GWAS) data have revealed that detectable genetic mosaicism involving large (>2 Mb) structural autosomal alterations occurs in a fraction of individuals. We present results for a set of 24,849 genotyped indiv...
Sampson, Joshua N;Wheeler, William A;Yeager, Meredith;Panagiotou, Orestis;Wang, Zhaoming;Berndt, Sonja I;Lan, Qing;Abnet, Christian C;Amundadottir, Laufey T;Figueroa, Jonine D;Landi, Maria Teresa;Mirabello, Lisa;Savage, Sharon A;Taylor, Philip R;De Vivo, Immaculata;McGlynn, Katherine A;Purdue, Mark P;Rajaraman, Preetha;Adami, Hans-Olov;Ahlbom, Anders;Albanes, Demetrius;Amary, Maria Fernanda;An, She-Juan;Andersson, Ulrika;Andriole, Gerald;Andrulis, Irene L;Angelucci, Emanuele;Ansell, Stephen M;Arici, Cecilia;Armstrong, Bruce K;Arslan, Alan A;Austin, Melissa A;Baris, Dalsu;Barkauskas, Donald A;Bassig, Bryan A;Becker, Nikolaus;Benavente, Yolanda;Benhamou, Simone;Berg, Christine;Van Den Berg, David;Bernstein, Leslie;Bertrand, Kimberly A;Birmann, Brenda M;Black, Amanda;Boeing, Heiner;Boffetta, Paolo;Boutron-Ruault, Marie-Christine;Bracci, Paige M;Brinton, Louise;Brooks-Wilson, Angela R;Bueno-de-Mesquita, H Bas;Burdett, Laurie;Buring, Julie;Butler, Mary Ann;Cai, Qiuyin;Cancel-Tassin, Geraldine;Canzian, Federico;Carrato, Alfredo;Carreon, Tania;Carta, Angela;Chan, John KC;Chang, Ellen T;Chang, Gee-Chen;Chang, I-Shou;Chang, Jiang;Chang-Claude, Jenny;Chen, Chien-Jen;Chen, Chih-Yi;Chen, Chu;Chen, Chung-Hsing;Chen, Constance;Chen, Hongyan;Chen, Kexin;Chen, Kuan-Yu;Chen, Kun-Chieh;Chen, Ying;Chen, Ying-Hsiang;Chen, Yi-Song;Chen, Yuh-Min;Chien, Li-Hsin;Chirlaque, María-Dolores;Choi, Jin Eun;Choi, Yi Young;Chow, Wong-Ho;Chung, Charles C;Clavel, Jacqueline;Clavel-Chapelon, Françoise;Cocco, Pierluigi;Colt, Joanne S;Comperat, Eva;Conde, Lucia;Connors, Joseph M;Conti, David;Cortessis, Victoria K;Cotterchio, Michelle;Cozen, Wendy;Crouch, Simon;Crous-Bou, Marta;Cussenot, Olivier;Davis, Faith G;Ding, Ti;Diver, W Ryan;Dorronsoro, Miren;Dossus, Laure;Duell, Eric J;Ennas, Maria Grazia;Erickson, Ralph L;Feychting, Maria;Flanagan, Adrienne M;Foretova, Lenka;Fraumeni, Joseph F;Freedman, Neal D;Beane Freeman, Laura E;Fuchs, Charles;Gago-Dominguez, Manuela;Gallinger, Steven;Gao, Yu-Tang;Gapstur, Susan M;Garcia-Closas, Montserrat;García-Closas, Reina;Gascoyne, Randy D;Gastier-Foster, Julie;Gaudet, Mia M;Gaziano, J Michael;Giffen, Carol;Giles, Graham G;Giovannucci, Edward;Glimelius, Bengt;Goggins, Michael;Gokgoz, Nalan;Goldstein, Alisa M;Gorlick, Richard;Gross, Myron;Grubb, Robert;Gu, Jian;Guan, Peng;Gunter, Marc;Guo, Huan;Habermann, Thomas M;Haiman, Christopher A;Halai, Dina;Hallmans, Goran;Hassan, Manal;Hattinger, Claudia;He, Qincheng;He, Xingzhou;Helzlsouer, Kathy;Henderson, Brian;Henriksson, Roger;Hjalgrim, Henrik;Hoffman-Bolton, Judith;Hohensee, Chancellor;Holford, Theodore R;Holly, Elizabeth A;Hong, Yun-Chul;Hoover, Robert N;Horn-Ross, Pamela L;Hosain, GM Monawar;Hosgood, H Dean;Hsiao, Chin-Fu;Hu, Nan;Hu, Wei;Hu, Zhibin;Huang, Ming-Shyan;Huerta, Jose-Maria;Hung, Jen-Yu;Hutchinson, Amy;Inskip, Peter D;Jackson, Rebecca D;Jacobs, Eric J;Jenab, Mazda;Jeon, Hyo-Sung;Ji, Bu-Tian;Jin, Guangfu;Jin, Li;Johansen, Christoffer;Johnson, Alison;Jung, Yoo Jin;Kaaks, Rudolph;Kamineni, Aruna;Kane, Eleanor;Kang, Chang Hyun;Karagas, Margaret R;Kelly, Rachel S;Khaw, Kay-Tee;Kim, Christopher;Kim, Hee Nam;Kim, Jin Hee;Kim, Jun Suk;Kim, Yeul Hong;Kim, Young Tae;Kim, Young-Chul;Kitahara, Cari M;Klein, Alison P;Klein, Robert J;Kogevinas, Manolis;Kohno, Takashi;Kolonel, Laurence N;Kooperberg, Charles;Kricker, Anne;Krogh, Vittorio;Kunitoh, Hideo;Kurtz, Robert C;Kweon, Sun-Seog;LaCroix, Andrea;Lawrence, Charles;Lecanda, Fernando;Lee, Victor Ho Fun;Li, Donghui;Li, Haixin;Li, Jihua;Li, Yao-Jen;Li, Yuqing;Liao, Linda M;Liebow, Mark;Lightfoot, Tracy;Lim, Wei-Yen;Lin, Chien-Chung;Lin, Dongxin;Lindstrom, Sara;Linet, Martha S;Link, Brian K;Liu, Chenwei;Liu, Jianjun;Liu, Li;Ljungberg, Börje;Lloreta, Josep;Di Lollo, Simonetta;Lu, Daru;Lund, Eiluv;Malats, Nuria;Mannisto, Satu;Le Marchand, Loic;Marina, Neyssa;Masala, Giovanna;Mastrangelo, Giuseppe;Matsuo, Keitaro;Maynadie, Marc;McKay, James;McKean-Cowdin, Roberta;Melbye, Mads;Melin, Beatrice S;Michaud, Dominique S;Mitsudomi, Tetsuya;Monnereau, Alain;Montalvan, Rebecca;Moore, Lee E;Mortensen, Lotte Maxild;Nieters, Alexandra;North, Kari E;Novak, Anne J;Oberg, Ann L;Offit, Kenneth;Oh, In-Jae;Olson, Sara H;Palli, Domenico;Pao, William;Park, In Kyu;Park, Jae Yong;Park, Kyong Hwa;Patiño-Garcia, Ana;Pavanello, Sofia;Peeters, Petra HM;Perng, Reury-Perng;Peters, Ulrike;Petersen, Gloria M;Picci, Piero;Pike, Malcolm C;Porru, Stefano;Prescott, Jennifer;Prokunina-Olsson, Ludmila;Qian, Biyun;Qiao, You-Lin;Rais, Marco;Riboli, Elio;Riby, Jacques;Risch, Harvey A;Rizzato, Cosmeri;Rodabough, Rebecca;Roman, Eve;Roupret, Morgan;Ruder, Avima M;Sanjose, Silvia de;Scelo, Ghislaine;Schned, Alan;Schumacher, Fredrick;Schwartz, Kendra;Schwenn, Molly;Scotlandi, Katia;Seow, Adeline;Serra, Consol;Serra, Massimo;Sesso, Howard D;Setiawan, Veronica Wendy;Severi, Gianluca;Severson, Richard K;Shanafelt, Tait D;Shen, Hongbing;Shen, Wei;Shin, Min-Ho;Shiraishi, Kouya;Shu, Xiao-Ou;Siddiq, Afshan;Sierrasesúmaga, Luis;Sihoe, Alan Dart Loon;Skibola, Christine F;Smith, Alex;Smith, Martyn T;Southey, Melissa C;Spinelli, John J;Staines, Anthony;Stampfer, Meir;Stern, Marianna C;Stevens, Victoria L;Stolzenberg-Solomon, Rachael S;Su, Jian;Su, Wu-Chou;Sund, Malin;Sung, Jae Sook;Sung, Sook Whan;Tan, Wen;Tang, Wei;Tardón, Adonina;Thomas, David;Thompson, Carrie A;Tinker, Lesley F;Tirabosco, Roberto;Tjønneland, Anne;Travis, Ruth C;Trichopoulos, Dimitrios;Tsai, Fang-Yu;Tsai, Ying-Huang;Tucker, Margaret;Turner, Jenny;Vajdic, Claire M;Vermeulen, Roel CH;Villano, Danylo J;Vineis, Paolo;Virtamo, Jarmo;Visvanathan, Kala;Wactawski-Wende, Jean;Wang, Chaoyu;Wang, Chih-Liang;Wang, Jiu-Cun;Wang, Junwen;Wei, Fusheng;Weiderpass, Elisabete;Weiner, George J;Weinstein, Stephanie;Wentzensen, Nicolas;White, Emily;Witzig, Thomas E;Wolpin, Brian M;Wong, Maria Pik;Wu, Chen;Wu, Guoping;Wu, Junjie;Wu, Tangchun;Wu, Wei;Wu, Xifeng;Wu, Yi-Long;Wunder, Jay S;Xiang, Yong-Bing;Xu, Jun;Xu, Ping;Yang, Pan-Chyr;Yang, Tsung-Ying;Ye, Yuanqing;Yin, Zhihua;Yokota, Jun;Yoon, Ho-Il;Yu, Chong-Jen;Yu, Herbert;Yu, Kai;Yuan, Jian-Min;Zelenetz, Andrew;Zeleniuch-Jacquotte, Anne;Zhang, Xu-Chao;Zhang, Yawei;Zhao, Xueying;Zhao, Zhenhong;Zheng, Hong;Zheng, Tongzhang;Zheng, Wei;Zhou, Baosen;Zhu, Meng;Zucca, Mariagrazia;Boca, Simina M;Cerhan, James R;Ferri, Giovanni M;Hartge, Patricia;Hsiung, Chao Agnes;Magnani, Corrado;Miligi, Lucia;Morton, Lindsay M;Smedby, Karin E;Teras, Lauren R;Vijai, Joseph;Wang, Sophia S;Brennan, Paul;Caporaso, Neil E;Hunter, David J;Kraft, Peter;Rothman, Nathaniel;Silverman, Debra T;Slager, Susan L;Chanock, Stephen J;Chatterjee, Nilanjan
Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and genetic correlation attributable to the additive effects of common single-nucleotide polymorphisms (SNPs) fo...
Sampson, Joshua N;Wheeler, William A;Yeager, Meredith;Panagiotou, Orestis;Wang, Zhaoming;Berndt, Sonja I;Lan, Qing;Abnet, Christian C;Amundadottir, Laufey T;Figueroa, Jonine D;Landi, Maria Teresa;Mirabello, Lisa;Savage, Sharon A;Taylor, Philip R;De Vivo, Immaculata;McGlynn, Katherine A;Purdue, Mark P;Rajaraman, Preetha;Adami, Hans-Olov;Ahlbom, Anders;Albanes, Demetrius;Amary, Maria Fernanda;An, She-Juan;Andersson, Ulrika;Andriole, Gerald;Andrulis, Irene L;Angelucci, Emanuele;Ansell, Stephen M;Arici, Cecilia;Armstrong, Bruce K;Arslan, Alan A;Austin, Melissa A;Baris, Dalsu;Barkauskas, Donald A;Bassig, Bryan A;Becker, Nikolaus;Benavente, Yolanda;Benhamou, Simone;Berg, Christine;Van Den Berg, David;Bernstein, Leslie;Bertrand, Kimberly A;Birmann, Brenda M;Black, Amanda;Boeing, Heiner;Boffetta, Paolo;Boutron-Ruault, Marie-Christine;Bracci, Paige M;Brinton, Louise;Brooks-Wilson, Angela R;Bueno-de-Mesquita, H Bas;Burdett, Laurie;Buring, Julie;Butler, Mary Ann;Cai, Qiuyin;Cancel-Tassin, Geraldine;Canzian, Federico;Carrato, Alfredo;Carreon, Tania;Carta, Angela;Chan, John K C;Chang, Ellen T;Chang, Gee-Chen;Chang, I-Shou;Chang, Jiang;Chang-Claude, Jenny;Chen, Chien-Jen;Chen, Chih-Yi;Chen, Chu;Chen, Chung-Hsing;Chen, Constance;Chen, Hongyan;Chen, Kexin;Chen, Kuan-Yu;Chen, Kun-Chieh;Chen, Ying;Chen, Ying-Hsiang;Chen, Yi-Song;Chen, Yuh-Min;Chien, Li-Hsin;Chirlaque, María-Dolores;Choi, Jin Eun;Choi, Yi Young;Chow, Wong-Ho;Chung, Charles C;Clavel, Jacqueline;Clavel-Chapelon, Françoise;Cocco, Pierluigi;Colt, Joanne S;Comperat, Eva;Conde, Lucia;Connors, Joseph M;Conti, David;Cortessis, Victoria K;Cotterchio, Michelle;Cozen, Wendy;Crouch, Simon;Crous-Bou, Marta;Cussenot, Olivier;Davis, Faith G;Ding, Ti;Diver, W Ryan;Dorronsoro, Miren;Dossus, Laure;Duell, Eric J;Ennas, Maria Grazia;Erickson, Ralph L;Feychting, Maria;Flanagan, Adrienne M;Foretova, Lenka;Fraumeni, Joseph F;Freedman, Neal D;Beane Freeman, Laura E;Fuchs, Charles;Gago-Dominguez, Manuela;Gallinger, Steven;Gao, Yu-Tang;Gapstur, Susan M;Garcia-Closas, Montserrat;García-Closas, Reina;Gascoyne, Randy D;Gastier-Foster, Julie;Gaudet, Mia M;Gaziano, J Michael;Giffen, Carol;Giles, Graham G;Giovannucci, Edward;Glimelius, Bengt;Goggins, Michael;Gokgoz, Nalan;Goldstein, Alisa M;Gorlick, Richard;Gross, Myron;Grubb, Robert;Gu, Jian;Guan, Peng;Gunter, Marc;Guo, Huan;Habermann, Thomas M;Haiman, Christopher A;Halai, Dina;Hallmans, Goran;Hassan, Manal;Hattinger, Claudia;He, Qincheng;He, Xingzhou;Helzlsouer, Kathy;Henderson, Brian;Henriksson, Roger;Hjalgrim, Henrik;Hoffman-Bolton, Judith;Hohensee, Chancellor;Holford, Theodore R;Holly, Elizabeth A;Hong, Yun-Chul;Hoover, Robert N;Horn-Ross, Pamela L;Hosain, G M Monawar;Hosgood, H Dean;Hsiao, Chin-Fu;Hu, Nan;Hu, Wei;Hu, Zhibin;Huang, Ming-Shyan;Huerta, Jose-Maria;Hung, Jen-Yu;Hutchinson, Amy;Inskip, Peter D;Jackson, Rebecca D;Jacobs, Eric J;Jenab, Mazda;Jeon, Hyo-Sung;Ji, Bu-Tian;Jin, Guangfu;Jin, Li;Johansen, Christoffer;Johnson, Alison;Jung, Yoo Jin;Kaaks, Rudolph;Kamineni, Aruna;Kane, Eleanor;Kang, Chang Hyun;Karagas, Margaret R;Kelly, Rachel S;Khaw, Kay-Tee;Kim, Christopher;Kim, Hee Nam;Kim, Jin Hee;Kim, Jun Suk;Kim, Yeul Hong;Kim, Young Tae;Kim, Young-Chul;Kitahara, Cari M;Klein, Alison P;Klein, Robert J;Kogevinas, Manolis;Kohno, Takashi;Kolonel, Laurence N;Kooperberg, Charles;Kricker, Anne;Krogh, Vittorio;Kunitoh, Hideo;Kurtz, Robert C;Kweon, Sun-Seog;LaCroix, Andrea;Lawrence, Charles;Lecanda, Fernando;Lee, Victor Ho Fun;Li, Donghui;Li, Haixin;Li, Jihua;Li, Yao-Jen;Li, Yuqing;Liao, Linda M;Liebow, Mark;Lightfoot, Tracy;Lim, Wei-Yen;Lin, Chien-Chung;Lin, Dongxin;Lindstrom, Sara;Linet, Martha S;Link, Brian K;Liu, Chenwei;Liu, Jianjun;Liu, Li;Ljungberg, Börje;Lloreta, Josep;Di Lollo, Simonetta;Lu, Daru;Lund, Eiluv;Malats, Nuria;Mannisto, Satu;Le Marchand, Loic;Marina, Neyssa;Masala, Giovanna;Mastrangelo, Giuseppe;Matsuo, Keitaro;Maynadie, Marc;McKay, James;McKean-Cowdin, Roberta;Melbye, Mads;Melin, Beatrice S;Michaud, Dominique S;Mitsudomi, Tetsuya;Monnereau, Alain;Montalvan, Rebecca;Moore, Lee E;Mortensen, Lotte Maxild;Nieters, Alexandra;North, Kari E;Novak, Anne J;Oberg, Ann L;Offit, Kenneth;Oh, In-Jae;Olson, Sara H;Palli, Domenico;Pao, William;Park, In Kyu;Park, Jae Yong;Park, Kyong Hwa;Patiño-Garcia, Ana;Pavanello, Sofia;Peeters, Petra H M;Perng, Reury-Perng;Peters, Ulrike;Petersen, Gloria M;Picci, Piero;Pike, Malcolm C;Porru, Stefano;Prescott, Jennifer;Prokunina-Olsson, Ludmila;Qian, Biyun;Qiao, You-Lin;Rais, Marco;Riboli, Elio;Riby, Jacques;Risch, Harvey A;Rizzato, Cosmeri;Rodabough, Rebecca;Roman, Eve;Roupret, Morgan;Ruder, Avima M;Sanjose, Silvia de;Scelo, Ghislaine;Schned, Alan;Schumacher, Fredrick;Schwartz, Kendra;Schwenn, Molly;Scotlandi, Katia;Seow, Adeline;Serra, Consol;Serra, Massimo;Sesso, Howard D;Setiawan, Veronica Wendy;Severi, Gianluca;Severson, Richard K;Shanafelt, Tait D;Shen, Hongbing;Shen, Wei;Shin, Min-Ho;Shiraishi, Kouya;Shu, Xiao-Ou;Siddiq, Afshan;Sierrasesúmaga, Luis;Sihoe, Alan Dart Loon;Skibola, Christine F;Smith, Alex;Smith, Martyn T;Southey, Melissa C;Spinelli, John J;Staines, Anthony;Stampfer, Meir;Stern, Marianna C;Stevens, Victoria L;Stolzenberg-Solomon, Rachael S;Su, Jian;Su, Wu-Chou;Sund, Malin;Sung, Jae Sook;Sung, Sook Whan;Tan, Wen;Tang, Wei;Tardón, Adonina;Thomas, David;Thompson, Carrie A;Tinker, Lesley F;Tirabosco, Roberto;Tjønneland, Anne;Travis, Ruth C;Trichopoulos, Dimitrios;Tsai, Fang-Yu;Tsai, Ying-Huang;Tucker, Margaret;Turner, Jenny;Vajdic, Claire M;Vermeulen, Roel C H;Villano, Danylo J;Vineis, Paolo;Virtamo, Jarmo;Visvanathan, Kala;Wactawski-Wende, Jean;Wang, Chaoyu;Wang, Chih-Liang;Wang, Jiu-Cun;Wang, Junwen;Wei, Fusheng;Weiderpass, Elisabete;Weiner, George J;Weinstein, Stephanie;Wentzensen, Nicolas;White, Emily;Witzig, Thomas E;Wolpin, Brian M;Wong, Maria Pik;Wu, Chen;Wu, Guoping;Wu, Junjie;Wu, Tangchun;Wu, Wei;Wu, Xifeng;Wu, Yi-Long;Wunder, Jay S;Xiang, Yong-Bing;Xu, Jun;Xu, Ping;Yang, Pan-Chyr;Yang, Tsung-Ying;Ye, Yuanqing;Yin, Zhihua;Yokota, Jun;Yoon, Ho-Il;Yu, Chong-Jen;Yu, Herbert;Yu, Kai;Yuan, Jian-Min;Zelenetz, Andrew;Zeleniuch-Jacquotte, Anne;Zhang, Xu-Chao;Zhang, Yawei;Zhao, Xueying;Zhao, Zhenhong;Zheng, Hong;Zheng, Tongzhang;Zheng, Wei;Zhou, Baosen;Zhu, Meng;Zucca, Mariagrazia;Boca, Simina M;Cerhan, James R;Ferri, Giovanni M;Hartge, Patricia;Hsiung, Chao Agnes;Magnani, Corrado;Miligi, Lucia;Morton, Lindsay M;Smedby, Karin E;Teras, Lauren R;Vijai, Joseph;Wang, Sophia S;Brennan, Paul;Caporaso, Neil E;Hunter, David J;Kraft, Peter;Rothman, Nathaniel;Silverman, Debra T;Slager, Susan L;Chanock, Stephen J;Chatterjee, Nilanjan
Machiela, Mitchell J;Zhou, Weiyin;Karlins, Eric;Sampson, Joshua N.;Freedman, Neal D;Yang, Qi;Hicks, Belynda D;Dagnall, Casey;Hautman, Christopher;Jacobs, Kevin B;Abnet, Christian C;Aldrich, Melinda C.;Amos, Christopher I;Amundadottir, Laufey T.;Arslan, Alan A.;Beane-Freeman, Laura E.;Berndt, Sonja I;Black, Amanda;Blot, William J;Bock, Cathryn H.;Bracci, Paige M.;Brinton, Louise A;Bueno-de-Mesquita, H Bas;Burdett, Laurie;Buring, Julie E;Butler, Mary Ann;Canzian, Federico;Carreón, Tania;Chaffee, Kari G.;Chang, I-Shou;Chatterjee, Nilanjan;Chen, Chu;Chen, Constance;Chen, Kexin;Chung, Charles C;Cook, Linda S;Crous Bou, Marta;Cullen, Michael;Davis, Faith G;De Vivo, Immaculata;Ding, Ti;Doherty, Jennifer;Duell, Eric J;Epstein, Caroline G.;Fan, Jin Hu;Figueroa, Jonine D;Fraumeni, Joseph F.;Friedenreich, Christine M.;Fuchs, Charles S.;Gallinger, Steven;Gao, Yu Tang;Gapstur, Susan M;García-Closas, Montserrat;Gaudet, Mia;Gaziano, J Michael;Giles, Graham;Gillanders, Elizabeth M;Giovannucci, Edward L;Goldin, Lynn;Goldstein, Alisa M;Haiman, Christopher A;Hallmans, Goran;Hankinson, Susan E;Harris, Curtis C;Henriksson, Roger;Holly, Elizabeth A.;Hong, Yun Chul;Hoover, Robert N;Hsiung, Chao A;Hu, Nan;Hu, Zhuo-Wei;Hunter, David J;Hutchinson, Amy;Jenab, Mazda;Johansen, Christoffer;Khaw, Kay-Tee;Kim, Hee Nam;Kim, Yeul Hong;Kim, Young Tae;Klein, Alison P.;Klein, Robert J;Koh, Woon-Puay;Kolonel, Laurence N;Kooperberg, Charles;Kraft, Peter;Krogh, Vittorio;Kurtz, Robert C.;LaCroix, Andrea Z;Lan, Qing;Landi, Maria Teresa;Marchand, Loic Le;Li, Donghui;Liang, Xiaolin;Liao, Linda M.;Lin, Dongxin;Liu, Jianjun;Lissowska, Jolanta;Lu, Lingeng;Magliocco, Anthony M;Malats, Núria;Matsuo, Keitaro;McNeill, Lorna H.;McWilliams, Robert R.;Melin, Beatrice S;Mirabello, Lisa;Moore, Lee;Olson, Sara H;Orlow, Irene;Park, Jae Yong;Patinõ-Garcia, Ana;Peplonska, Beata;Peters, Ulrike;Petersen, Gloria M.;Pooler, Loreall C;Prescott, Jennifer;Prokunina-Olsson, Ludmila;Purdue, Mark P.;Qiao, You Lin;Rajaraman, Preetha;Real, Francisco X.;Riboli, Elio;Risch, Harvey A;Rodríguez-Santiago, Benjamín;Ruder, Avima M;Savage, Sharon A;Schumacher, Fredrick;Schwartz, Ann G.;Schwartz, Kendra L.;Seow, Adeline;Wendy Setiawan, Veronica;Severi, Gianluca;Shen, Hongbing;Sheng, Xin;Shin, Min Ho;Shu, Xiao-Ou;Silverman, Debra T.;Spitz, Margaret R;Stevens, Victoria L;Stolzenberg-Solomon, Rachael;Stram, Daniel O;Tang, Ze Zhong;Taylor, Philip R.;Teras, Lauren R.;Tobias, Geoffrey S.;Van Den Berg, David;Visvanathan, Kala;Wacholder, Sholom;Wang, Jiu Cun;Wang, Zhaoming;Wentzensen, Nicolas;Wheeler, William;White, Emily;Wiencke, John K;Wolpin, Brian M.;Wong, Maria Pik;Wu, Chen;Wu, Tangchun;Wu, Xifeng;Wu, Yi Long;Wunder, Jay S.;Xia, Lucy;Yang, Hannah P;Yang, Pan Chyr;Yu, Kai;Zanetti, Krista A.;Zeleniuch-Jacquotte, Anne;Zheng, Wei;Zhou, Baosen;Ziegler, Regina G;Perez-Jurado, Luis A.;Caporaso, Neil E.;Rothman, Nathaniel;Tucker, Margaret A;Dean, Michael C.;Yeager, Meredith;Chanock, Stephen J
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Scott, Robert A;Freitag, Daniel F;Li, Li;Chu, Audrey Y;Surendran, Praveen;Young, Robin;Grarup, Niels;Stancakova, Alena;Chen, Yuning;Varga, Tibor V;Yaghootkar, Hanieh;Luan, Jian'an;Zhao, Jing Hua;Willems, Sara M;Wessel, Jennifer;Wang, Shuai;Maruthur, Nisa;Michailidou, Kyriaki;Pirie, Ailith;van der Lee, Sven J;Gillson, Christopher;Al Olama, Ali Amin;Amouyel, Philippe;Arriola, Larraitz;Arveiler, Dominique;Aviles-Olmos, Iciar;Balkau, Beverley;Barricarte, Aurelio;Barroso, Ines;Garcia, Sara Benlloch;Bis, Joshua C;Blankenberg, Stefan;Boehnke, Michael;Boeing, Heiner;Boerwinkle, Eric;Borecki, Ingrid B;Bork-Jensen, Jette;Bowden, Sarah;Caldas, Carlos;Caslake, Muriel;Cupples, L Adrienne;Cruchaga, Carlos;Czajkowski, Jacek;den Hoed, Marcel;Dunn, Janet A;Earl, Helena M;Ehret, Georg B;Ferrannini, Ele;Ferrieres, Jean;Foltynie, Thomas;Ford, Ian;Forouhi, Nita G;Gianfagna, Francesco;Gonzalez, Carlos;Grioni, Sara;Hiller, Louise;Jansson, Jan-Hakan;Jorgensen, Marit E;Jukema, J Wouter;Kaaks, Rudolf;Kee, Frank;Kerrison, Nicola D;Key, Timothy J;Kontto, Jukka;Kote-Jarai, Zsofia;Kraja, Aldi T;Kuulasmaa, Kari;Kuusisto, Johanna;Linneberg, Allan;Liu, Chunyu;Marenne, Galle;Mohlke, Karen L;Morris, Andrew P;Muir, Kenneth;Mueller-Nurasyid, Martina;Munroe, Patricia B;Navarro, Carmen;Nielsen, Sune F;Nilsson, Peter M;Nordestgaard, Borge G;Packard, Chris J;Palli, Domenico;Panico, Salvatore;Peloso, Gina M;Perola, Markus;Peters, Annette;Poole, Christopher J;Quiros, J Ramn;Rolandsson, Olov;Sacerdote, Carlotta;Salomaa, Veikko;Sanchez, Mara-Jose;Sattar, Naveed;Sharp, Stephen J;Sims, Rebecca;Slimani, Nadia;Smith, Jennifer A;Thompson, Deborah J;Trompet, Stella;Tumino, Rosario;van der A, Daphne L;van der Schouw, Yvonne T;Virtamo, Jarmo;Walker, Mark;Walter, Klaudia;Abraham, Jean E;Amundadottir, Laufey T;Aponte, Jennifer L;Butterworth, Adams;Dupuis, Josee;Easton, Douglas F;Eeles, Rosalind A;Erdmann, Jeanette;Franks, Paul W;Frayling, Timothy M;Hansen, Torben;Howson, Joanna MM;Jorgensen, Torben;Kooner, Jaspal;Laakso, Markku;Langenberg, Claudia;McCarthy, Mark I;Pankow, James S;Pedersen, Oluf;Riboli, Elio;Rotter, Jerome I;Saleheen, Danish;Samani, Nilesh J;Schunkert, Heribert;Vollenweider, Peter;O'Rahilly, Stephen;Deloukas, Panos;Danesh, John;Goodarzi, Mark O;Kathiresan, Sekar;Meigs, James B;Ehm, Margaret G;Wareham, Nicholas J;Waterworth, Dawn M;Consortium, CVD50;Consortium, GERAD-EC;Grp, Neurology Working;CHARGE,;Consortiu, Alzheimer's Dis Genetics;Consortium, Pancreatic Canc Cohort;European, Prospective Invest Into C;EPIC-InterAct,;Consortium, CHARGE;Consortium, CHD Exome;Consortium, CARDIOGRAM Exome
Scott, Robert;Freitag, Daniel F;Li, Li;Chu, Audrey Y;Surendran, Praveen;Young, Robin;Grarup, Niels;Stancáková, Alena;Chen, Yuning;Varga, Tibor V;Yaghootkar, Hanieh;Luan, Jian'an;Zhao, Jing Hua;Willems, Sara;Wessel, Jennifer;Wang, Shuai;Maruthur, Nisa;Michailidou, Kyriaki;Pirie, Ailith;van, der Lee Sven J;Gillson, Christopher;Al, Olama Ali Amin;Amouyel, Philippe;Arriola, Larraitz;Arveiler, Dominique;Aviles-Olmos, Iciar;Balkau, Beverley;Barricarte, Aurelio;Barroso, Maria;Garcia, Sara Benlloch;Bis, Joshua C;Blankenberg, Stefan;Boehnke, Michael;Boeing, Heiner;Boerwinkle, Eric;Borecki, Ingrid B;Bork-Jensen, Jette;Bowden, Sarah;Caldas, Carlos;Caslake, Muriel;Cupples, L Adrienne;Cruchaga, Carlos;Czajkowski, Jacek;den, Hoed Marcel;Dunn, Janet A;Earl, Helena;Ehret, Georg B;Ferrannini, Ele;Ferrieres, Jean;Foltynie, Thomas;Ford, Ian;Forouhi, Nita;Gianfagna, Francesco;Gonzalez, Carlos;Grioni, Sara;Hiller, Louise;Jansson, Jan-Håkan;Jørgensen, Marit E;Jukema, J Wouter;Kaaks, Rudolf;Kee, Frank;Kerrison, Nicola D;Key, Timothy J;Kontto, Jukka;Kote-Jarai, Zsofia;Kraja, Aldi T;Kuulasmaa, Kari;Kuusisto, Johanna;Linneberg, Allan;Liu, Chunyu;Marenne, Gaëlle;Mohlke, Karen L;Morris, Andrew P;Muir, Kenneth;Müller-Nurasyid, Martina;Munroe, Patricia B;Navarro, Carmen;Nielsen, Sune F;Nilsson, Peter M;Nordestgaard, Børge G;Packard, Chris J;Palli, Domenico;Panico, Salvatore;Peloso, Gina M;Perola, Markus;Peters, Annette;Poole, Christopher J;Quirós, J Ramón;Rolandsson, Olov;Sacerdote, Carlotta;Salomaa, Veikko;Sánchez, María-José;Sattar, Naveed;Sharp, Stephen;Sims, Rebecca;Slimani, Nadia;Smith, Jennifer A;Thompson, Deborah;Trompet, Stella;Tumino, Rosario;van, der A Daphne L;van, der Schouw Yvonne T;Virtamo, Jarmo;Walker, Mark;Walter, Klaudia;Abraham, Jean;Amundadottir, Laufey T;Aponte, Jennifer L;Butterworth, Adam;Dupuis, Josée;Easton, Douglas;Eeles, Rosalind A;Erdmann, Jeanette;Franks, Paul W;Frayling, Timothy M;Hansen, Torben;Howson, Joanna;Jørgensen, Torben;Kooner, Jaspal;Laakso, Markku;Langenberg, Claudia;McCarthy, Mark I;Pankow, James S;Pedersen, Oluf;Riboli, Elio;Rotter, Jerome I;Saleheen, Danish;Samani, Nilesh J;Schunkert, Heribert;Vollenweider, Peter;O’Rahilly, Stephen;Deloukas, Panos;Danesh, John;Goodarzi, Mark O;Kathiresan, Sekar;Meigs, James B;Ehm, Margaret G;Wareham, Nicholas;Waterworth, Dawn M
Regulatory authorities have indicated that new drugs to treat type 2 diabetes (T2D) should not be associated with an unacceptable increase in cardiovascular risk. Human genetics may be able to guide development of antidiabetic therapies by predicting...
Walsh, Naomi;Zhang, Han;Hyland, Paula L;Yang, Qi;Mocci, Evelina;Zhang, Mingfeng;Childs, Erica J;Collins, Irene;Wang, Zhaoming;Arslan, Alan A;Beane-Freeman, Laura;Bracci, Paige M;Brennan, Paul;Canzian, Federico;Duell, Eric J;Gallinger, Steven;Giles, Graham G;Goggins, Michael;Goodman, Gary E;Goodman, Phyllis J;Hung, Rayjean J;Kooperberg, Charles;Kurtz, Robert C;Malats, Núria;LeMarchand, Loic;Neale, Rachel E;Olson, Sara H;Scelo, Ghislaine;Shu, Xiao O;Van Den Eeden, Stephen K;Visvanathan, Kala;White, Emily;Zheng, Wei;Albanes, Demetrius;Andreotti, Gabriella;Babic, Ana;Bamlet, William R;Berndt, Sonja I;Borgida, Ayelet;Boutron-Ruault, Marie-Christine;Brais, Lauren;Brennan, Paul;Bueno-de-Mesquita, Bas;Buring, Julie;Chaffee, Kari G;Chanock, Stephen;Cleary, Sean;Cotterchio, Michelle;Foretova, Lenka;Fuchs, Charles;M Gaziano, J Michael;Giovannucci, Edward;Goggins, Michael;Hackert, Thilo;Haiman, Christopher;Hartge, Patricia;Hasan, Manal;Helzlsouer, Kathy J;Herman, Joseph;Holcatova, Ivana;Holly, Elizabeth A;Hoover, Robert;Hung, Rayjean J;Janout, Vladimir;Klein, Eric A;Kurtz, Robert C;Laheru, Daniel;Lee, I-Min;Lu, Lingeng;Malats, Núria;Mannisto, Satu;Milne, Roger L;Oberg, Ann L;Orlow, Irene;Patel, Alpa V;Peters, Ulrike;Porta, Miquel;Real, Francisco X;Rothman, Nathaniel;Sesso, Howard D;Severi, Gianluca;Silverman, Debra;Strobel, Oliver;Sund, Malin;Thornquist, Mark D;Tobias, Geoffrey S;Wactawski-Wende, Jean;Wareham, Nick;Weiderpass, Elisabete;Wentzensen, Nicolas;Wheeler, William;Yu, Herbert;Zeleniuch-Jacquotte, Anne;Kraft, Peter;Li, Donghui;Jacobs, Eric J;Petersen, Gloria M;Wolpin, Brian M;Risch, Harvey A;Amundadottir, Laufey T;Yu, Kai;Klein, Alison P;Stolzenberg-Solomon, Rachael Z
Genome-wide association studies (GWAS) identify associations of individual single-nucleotide polymorphisms (SNPs) with cancer risk but usually only explain a fraction of the inherited variability. Pathway analysis of genetic variants is a powerful to...